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Select item 112585701.

New insights into the role of tetraspanin 6, 7, and 8 in physiology and pathology

Monika Mrozowska, Tomasz Górnicki, Mateusz Olbromski, Aleksandra Izabela Partyńska, Piotr Dzięgiel, Agnieszka Rusak

Cancer Med. 2024 Jul; 13(14): e7390. Published online 2024 Jul 19. doi: 10.1002/cam4.7390

PMCID:: PMC11258570

Abstract Article PDF–1.3M

Select item 98281092.

Loss of tetraspanin‐7 expression reduces pancreatic β‐cell exocytosis Ca²⁺ sensitivity but has limited effect on systemic metabolism

Kerry McLaughlin, Samuel Acreman, Sameena Nawaz, Joseph Cutteridge, Anne Clark, Jakob G. Knudsen, Geoffrey Denwood, Aliya F. Spigelman, Jocelyn E. Manning Fox, Sumeet Pal Singh, Patrick E. MacDonald, Benoit Hastoy, Quan Zhang

Diabet Med. 2022 Dec; 39(12): e14984. Published online 2022 Oct 31. doi: 10.1111/dme.14984

PMCID:: PMC9828109

Abstract Article PDF–5.6M

Select item 93485763.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 73950105.

Autoimmunity to tetraspanin-7 in type 1 diabetes

Kerry A. McLaughlin, Melissa A. Tombs, Michael R. Christie

Med Microbiol Immunol. 2020; 209(4): 437–445. Published online 2020 Apr 20. doi: 10.1007/s00430-020-00674-2

PMCID:: PMC7395010

Abstract Article PDF–679K

Select item 71699836.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 71001767.

Strategies for Targeting Tetraspanin Proteins: Potential Therapeutic Applications in Microbial Infections

Noha Hassuna, Peter N. Monk, Gregory W. Moseley, Lynda J. Partridge

BioDrugs. 2009; 23(6): 341–359. Published online 2012 Aug 22. doi: 10.2165/11315650-000000000-00000

PMCID:: PMC7100176

Abstract Article PDF–563K

Select item 70591798.

Dendritic Cell Maturation Regulates TSPAN7 Function in HIV-1 Transfer to CD4⁺ T Lymphocytes

Brieuc P. Perot, Victor García-Paredes, Marine Luka, Mickaël M. Ménager

Front Cell Infect Microbiol. 2020; 10: 70. Published online 2020 Feb 28. doi: 10.3389/fcimb.2020.00070

PMCID:: PMC7059179

Abstract Article PDF–2.5M

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 537173010.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 483319211.

Targeted Next‐Generation Sequencing Analysis of 1,000 Individuals with Intellectual Disability

Detelina Grozeva, Keren Carss, Olivera Spasic‐Boskovic, Maria‐Isabel Tejada, Jozef Gecz, Marie Shaw, Mark Corbett, Eric Haan, Elizabeth Thompson, Kathryn Friend, Zaamin Hussain, Anna Hackett, Michael Field, Alessandra Renieri, Roger Stevenson, Charles Schwartz, James A.B. Floyd, Jamie Bentham, Catherine Cosgrove, Bernard Keavney, Shoumo Bhattacharya, Italian X‐linked Mental Retardation Project, UK10K Consortium, GOLD Consortium, Matthew Hurles, F. Lucy Raymond

Hum Mutat. 2015 Dec; 36(12): 1197–1204. Published online 2015 Sep 30. doi: 10.1002/humu.22901

PMCID:: PMC4833192

Abstract Article PDF–230K

Select item 475289412.

Actin dynamics regulates dendritic cell-mediated transfer of HIV-1 to T cells

Mickaël M. Ménager, Dan R. Littman

Cell. Author manuscript; available in PMC 2017 Feb 11.

Published in final edited form as: Cell. 2016 Feb 11; 164(4): 695–709. Published online 2016 Jan 28. doi: 10.1016/j.cell.2015.12.036

PMCID:: PMC4752894

Abstract Article PDF–1.7M

Select item 460899713.

Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef

Nicholas J. Matheson, Jonathan Sumner, Kim Wals, Radu Rapiteanu, Michael P. Weekes, Raphael Vigan, Julia Weinelt, Michael Schindler, Robin Antrobus, Ana S.H. Costa, Christian Frezza, Clary B. Clish, Stuart J.D. Neil, Paul J. Lehner

Cell Host Microbe. 2015 Oct 14; 18(4): 409–423. doi: 10.1016/j.chom.2015.09.003

PMCID:: PMC4608997

Abstract Article PDF–3.8M

Select item 424911314.

HIV-1 Nef and Vpu Are Functionally Redundant Broad-Spectrum Modulators of Cell Surface Receptors, Including Tetraspanins

Claudia Haller, Birthe Müller, Joëlle V. Fritz, Miguel Lamas-Murua, Bettina Stolp, François M. Pujol, Oliver T. Keppler, Oliver T. Fackler

J Virol. 2014 Dec; 88(24): 14241–14257. doi: 10.1128/JVI.02333-14

PMCID:: PMC4249113

Abstract Article PDF–1.6M

Select item 400459815.

Systematic identification of pathological lamin A interactors

Travis A. Dittmer, Nidhi Sahni, Nard Kubben, David E. Hill, Marc Vidal, Rebecca C. Burgess, Vassilis Roukos, Tom Misteli

Mol Biol Cell. 2014 May 1; 25(9): 1493–1510. doi: 10.1091/mbc.E14-02-0733

PMCID:: PMC4004598

Abstract Article PDF–3.5M

Select item 352423916.

Brain Transcriptome-Wide Screen for HIV-1 Nef Protein Interaction Partners Reveals Various Membrane-Associated Proteins

Ellen C. Kammula, Jessica Mötter, Alexandra Gorgels, Esther Jonas, Silke Hoffmann, Dieter Willbold

PLoS One. 2012; 7(12): e51578. Published online 2012 Dec 17. doi: 10.1371/journal.pone.0051578

PMCID:: PMC3524239

Abstract Article PDF–705K

Select item 331499717.

The X-Linked Intellectual Disability Protein TSPAN7 Regulates Excitatory Synapse Development and AMPAR Trafficking

Silvia Bassani, Lorenzo A. Cingolani, Pamela Valnegri, Alessandra Folci, Jonathan Zapata, Antonella Gianfelice, Carlo Sala, Yukiko Goda, Maria Passafaro

Neuron. 2012 Mar 22; 73(6): 1143–1158. doi: 10.1016/j.neuron.2012.01.021

PMCID:: PMC3314997

Abstract Article

Select item 328913918.

Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia

A Piton, J Gauthier, FF Hamdan, RG Lafrenière, Y Yang, E Henrion, S Laurent, A Noreau, P Thibodeau, L Karemera, D Spiegelman, F Kuku, J Duguay, L Destroismaisons, P Jolivet, M Côté, K Lachapelle, O Diallo, A Raymond, C Marineau, N Champagne, L Xiong, C Gaspar, J-B Rivière, J Tarabeux, P Cossette, M-O Krebs, JL Rapoport, A Addington, LE DeLisi, L Mottron, R Joober, E Fombonne, P Drapeau, GA Rouleau

Mol Psychiatry. Author manuscript; available in PMC 2012 Feb 28.

Published in final edited form as: Mol Psychiatry. 2011 Aug; 16(8): 867–880. Published online 2010 May 18. doi: 10.1038/mp.2010.54

PMCID:: PMC3289139

Abstract Article PDF–1.2M

Select item 318838819.

Leveraging the power of next-generation sequencing to generate interactome datasets

Haiyuan Yu, Leah Tardivo, Stanley Tam, Evan Weiner, Fana Gebreab, Changyu Fan, Nenad Svrzikapa, Tomoko Hirozane-Kishikawa, Edward Rietman, Xinping Yang, Julie Sahalie, Kourosh Salehi-Ashtiani, Tong Hao, Michael E. Cusick, David E. Hill, Frederick P. Roth, Pascal Braun, Marc Vidal

Nat Methods. Author manuscript; available in PMC 2011 Dec 1.

Published in final edited form as: Nat Methods. 2011 Jun; 8(6): 478–480. Published online 2011 Apr 24. doi: 10.1038/nmeth.1597

PMCID:: PMC3188388

Abstract Article PDF–932K

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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