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Select item 107561201.

Has-miR-300—GADD45B promotes melanoma growth via cell cycle

Long Chen, Chenglong Fang, Xiaoxue Yuan, Mengqi Liu, Ping Wu, Li Zhong, Zhiyong Chen

Aging (Albany NY) 2023 Dec 15; 15(23): 13920–13943. Published online 2023 Dec 7. doi: 10.18632/aging.205276

Correction in:: Aging (Albany NY). 2024 Jan 15; 16(1): 983.

PMCID:: PMC10756120

Abstract Article PDF–3.7M

Select item 104714512.

Key Roles of p53 Signaling Pathway-Related Factors GADD45B and SERPINE1 in the Occurrence and Development of Gastric Cancer

Yaoqing Li, Liyijing Shen, Kelong Tao, Guangen Xu, Kewei Ji

Mediators Inflamm. 2023; 2023: 6368893. Published online 2023 Aug 24. doi: 10.1155/2023/6368893

PMCID:: PMC10471451

Abstract Article PDF–5.7M

Select item 104417933.

GADD45B regulates the carcinogenesis process of chronic atrophic gastritis and the metabolic pathways of gastric cancer

Wei Xu, Tianxiao Jiang, Kanger Shen, Dongxu Zhao, Man Zhang, Wenxin Zhu, Yunfei Liu, Chunfang Xu

Front Endocrinol (Lausanne) 2023; 14: 1224832. Published online 2023 Aug 7. doi: 10.3389/fendo.2023.1224832

PMCID:: PMC10441793

Abstract Article PDF–30M

Select item 92626144.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 88421655.

CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system

Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar

Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629

PMCID:: PMC8842165

Abstract Article PDF–3.0M

Select item 88116356.

Single‐cell transcriptomics identifies Gadd45b as a regulator of herpesvirus‐reactivating neurons

Hui‐Lan Hu, Kalanghad P Srinivas, Shuoshuo Wang, Moses V Chao, Timothee Lionnet, Ian Mohr, Angus C Wilson, Daniel P Depledge, Tony T Huang

EMBO Rep. 2022 Feb 3; 23(2): e53543. Published online 2021 Nov 29. doi: 10.15252/embr.202153543

PMCID:: PMC8811635

Abstract Article PDF–5.5M

Select item 82855127.

Growth arrest and DNA damage-inducible proteins (GADD45) in psoriasis

Pedro Rodríguez-Jiménez, Lola Fernández-Messina, María C. Ovejero-Benito, Pablo Chicharro, Paula Vera-Tomé, Alicia Vara, Danay Cibrian, Pedro Martínez-Fleta, María Jiménez-Fernández, Inés Sánchez-García, Mar Llamas-Velasco, Francisco Abad-Santos, Francisco Sánchez-Madrid, Esteban Dauden, Hortensia de la Fuente

Sci Rep. 2021; 11: 14579. Published online 2021 Jul 16. doi: 10.1038/s41598-021-93780-x

PMCID:: PMC8285512

Abstract Article PDF–3.1M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 72037429.

GADD45B Transcript Is a Prognostic Marker in Papillary Thyroid Carcinoma Patients Treated With Total Thyroidectomy and Radioiodine Therapy

Mateus C. Barros-Filho, Julia B. H. de Mello, Fabio A. Marchi, Clóvis A. L. Pinto, Igor C. da Silva, Patricia K. F. Damasceno, Milena B. P. Soares, Luiz P. Kowalski, Silvia R. Rogatto

Front Endocrinol (Lausanne) 2020; 11: 269. Published online 2020 Apr 30. doi: 10.3389/fendo.2020.00269

PMCID:: PMC7203742

Abstract Article PDF–887K

Select item 716998310.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 632529611.

Fluorescent labeling of CRISPR/Cas9 RNP for gene knockout in HSPCs and iPSCs reveals an essential role for GADD45b in stress response

Masoud Nasri, Perihan Mir, Benjamin Dannenmann, Diana Amend, Tessa Skroblyn, Yun Xu, Klaus Schulze-Osthoff, Maksim Klimiankou, Karl Welte, Julia Skokowa

Blood Adv. 2019 Jan 8; 3(1): 63–71. Published online 2019 Jan 8. doi: 10.1182/bloodadvances.2017015511

PMCID:: PMC6325296

Abstract Article PDF–1.3M

Select item 598100212.

Probing the interaction interface of the GADD45β/MKK7 and MKK7/DTP3 complexes by chemical cross-linking mass spectrometry

Camilla Rega, Rosita Russo, Annalia Focà, Annamaria Sandomenico, Emanuela Iaccarino, Domenico Raimondo, Edoardo Milanetti, Laura Tornatore, Guido Franzoso, Paolo Vincenzo Pedone, Menotti Ruvo, Angela Chambery

Int J Biol Macromol. 2018 Jul 15; 114: 114–123. doi: 10.1016/j.ijbiomac.2018.03.090

PMCID:: PMC5981002

Abstract Article

Select item 593559513.

GADD45β loss ablates innate immunosuppression in cancer

Daniela Verzella, Jason Bennett, Mariafausta Fischietti, Anil K. Thotakura, Camilla Recordati, Fabio Pasqualini, Daria Capece, Davide Vecchiotti, Daniel D’Andrea, Barbara Di Francesco, Marcella De Maglie, Federica Begalli, Laura Tornatore, Salvatore Papa, Toby Lawrence, Stuart J. Forbes, Antonio Sica, Edoardo Alesse, Francesca Zazzeroni, Guido Franzoso

Cancer Res. Author manuscript; available in PMC 2018 Sep 1.

Published in final edited form as: Cancer Res. 2018 Mar 1; 78(5): 1275–1292. Published online 2017 Dec 26. doi: 10.1158/0008-5472.CAN-17-1833

PMCID:: PMC5935595

Abstract Article PDF–3.1M

Select item 553161114.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 534271315.

A signaling cascade including ARID1A, GADD45B and DUSP1 induces apoptosis and affects the cell cycle of germ cell cancers after romidepsin treatment

Daniel Nettersheim, Sina Jostes, Martin Fabry, Friedemann Honecker, Valerie Schumacher, Jutta Kirfel, Glen Kristiansen, Hubert Schorle

Oncotarget. 2016 Nov 15; 7(46): 74931–74946. Published online 2016 Aug 27. doi: 10.18632/oncotarget.11647

PMCID:: PMC5342713

Abstract Article PDF–6.5M

Select item 524435216.

Kaposi's Sarcoma-Associated Herpesvirus MicroRNAs Target GADD45B To Protect Infected Cells from Cell Cycle Arrest and Apoptosis

Xiaoyan Liu, Christine Happel, Joseph M. Ziegelbauer

J Virol. 2017 Feb 1; 91(3): e02045-16. Prepublished online 2016 Nov 16. Published online 2017 Jan 18. doi: 10.1128/JVI.02045-16

PMCID:: PMC5244352

Abstract Article PDF–3.2M

Select item 504190417.

Genetic variants of GADD45A, GADD45B and MAPK14 predict platinum-based chemotherapy-induced toxicities in Chinese patients with non-small cell lung cancer

Ming Jia, Meiling Zhu, Mengyun Wang, Menghong Sun, Ji Qian, Fei Ding, Jianhua Chang, Qingyi Wei

Oncotarget. 2016 May 3; 7(18): 25291–25303. Published online 2016 Mar 14. doi: 10.18632/oncotarget.8052

PMCID:: PMC5041904

Abstract Article PDF–2.9M

Select item 492468418.

GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration

Rodrigo E. Tamura, Juliano D. Paccez, Kristal C. Duncan, Mirian G. Morale, Fernando M. Simabuco, Simon Dillon, Ricardo G. Correa, Xuesong Gu, Towia A. Libermann, Luiz F. Zerbini

Oncotarget. 2016 Mar 22; 7(12): 13865–13879. Published online 2016 Feb 12. doi: 10.18632/oncotarget.7355

PMCID:: PMC4924684

Abstract Article PDF–3.0M

Select item 471464719.

Identification of Growth Arrest and DNA-Damage-Inducible Gene β (GADD45β) as a Novel Tumor Suppressor in Pituitary Gonadotrope Tumors

Katherine A. Michaelis, Aaron J. Knox, Mei Xu, Katja Kiseljak-Vassiliades, Michael G. Edwards, Mark Geraci, B. K. Kleinschmidt-DeMasters, Kevin O. Lillehei, Margaret E. Wierman

Endocrinology. 2011 Oct; 152(10): 3603–3613. Published online 2011 Aug 2. doi: 10.1210/en.2011-0109

PMCID:: PMC4714647

Abstract Article

Select item 419733520.

Cancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitors

Laura Tornatore, Annamaria Sandomenico, Domenico Raimondo, Caroline Low, Alberto Rocci, Cathy Tralau-Stewart, Daria Capece, Daniel D’Andrea, Marco Bua, Eileen Boyle, Mark van Duin, Pietro Zoppoli, Albert Jaxa-Chamiec, Anil K. Thotakura, Julian Dyson, Brian A. Walker, Antonio Leonardi, Angela Chambery, Christoph Driessen, Pieter Sonneveld, Gareth Morgan, Antonio Palumbo, Anna Tramontano, Amin Rahemtulla, Menotti Ruvo, Guido Franzoso

Cancer Cell. 2014 Oct 13; 26(4): 495–508. doi: 10.1016/j.ccr.2014.07.027

Correction in:: Cancer Cell. 2014 Dec 8; 26(6): 938.

PMCID:: PMC4197335

Abstract Article

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