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Select item 109332671.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 105917732.

EGR1/LINC00839/SOX5 axis modulates migration, invasion and Gemcitabine resistance of bladder cancer cells

Zunxian Wang, Bo Wei, Shuxia Ma

Cancer Biol Ther. 2023; 24(1): 2270106. Published online 2023 Oct 20. doi: 10.1080/15384047.2023.2270106

PMCID:: PMC10591773

Abstract Article PDF–4.9M

Select item 101917883.

circ-LDLRAD3 Knockdown Reduces Cisplatin Chemoresistance and Inhibits the Development of Gastric Cancer with Cisplatin Resistance through miR-588 Enrichment-Mediated SOX5 Inhibition

Qianping Liang, Feifei Chu, Lei Zhang, Yuanyuan Jiang, Lu Li, Huili Wu

Gut Liver. 2023 May 15; 17(3): 389–403. Published online 2022 Aug 17. doi: 10.5009/gnl210195

PMCID:: PMC10191788

Abstract Article PDF–6.4M

Select item 99093224.

SOX5 promotes cell growth and migration through modulating DNMT1/p21 pathway in bladder cancer: SOX5/DNMT1/p21 pathway in BC

Longxiang Wu, Zhongqing Yang, Guoyu Dai, Benyi Fan, Junbin Yuan, Yalin Liu, Peihua Liu, Zhenyu Ou

Acta Biochim Biophys Sin (Shanghai) 2022 Jul; 54(7): 987–998. Published online 2022 Jun 21. doi: 10.3724/abbs.2022075

PMCID:: PMC9909322

Abstract Article PDF–15M

Select item 90636785.

Widening of the genetic and clinical spectrum of Lamb–Shaffer syndrome, a neurodevelopmental disorder due to SOX5 haploinsufficiency

Ash Zawerton, Cyril Mignot, Ashley Sigafoos, Patrick R. Blackburn, Abdul Haseeb, Kirsty McWalter, Shoji Ichikawa, Caroline Nava, Boris Keren, Perrine Charles, Isabelle Marey, Anne-Claude Tabet, Jonathan Levy, Laurence Perrin, Andreas Hartmann, Gaetan Lesca, Caroline Schluth-Bolard, Pauline Monin, Sophie Dupuis-Girod, Maria J. Guillen Sacoto, Rhonda E. Schnur, Zehua Zhu, Alice Poisson, Salima El Chehadeh, Yves Alembik, Ange-Line Bruel, Daphné Lehalle, Sophie Nambot, Sébastien Moutton, Sylvie Odent, Sylvie Jaillard, Christèle Dubourg, Yvonne Hilhorst-Hofstee, Tina Barbaro-Dieber, Lucia Ortega, Elizabeth J. Bhoj, Diane Masser-Frye, Lynne M. Bird, Kristin Lindstrom, Keri M. Ramsey, Vinodh Narayanan, Emily Fassi, Marcia Willing, Trevor Cole, Claire G. Salter, Rhoda Akilapa, Anthony Vandersteen, Natalie Canham, Patrick Rump, Erica H. Gerkes, Klein Jolien S. Wassink-Ruiter, Emilia Bijlsma, Mariëtte J. V. Hoffer, Marcelo Vargas, Antonina Wojcik, Florian Cherik, Christine Francannet, Jill A. Rosenfeld, Keren Machol, Daryl A. Scott, Carlos A. Bacino, Xia Wang, Gary D. Clark, Marta Bertoli, Simon Zwolinski, Rhys H. Thomas, Ela Akay, Richard C. Chang, Rebekah Bressi, Rossana Sanchez Russo, Myriam Srour, Laura Russell, Anne-Marie E. Goyette, Lucie Dupuis, Roberto Mendoza-Londono, Catherine Karimov, Maries Joseph, Mathilde Nizon, Benjamin Cogné, Alma Kuechler, Amélie Piton, Deciphering Developmental Disorder Study, Eric W. Klee, Véronique Lefebvre, Karl J. Clark, Christel Depienne

Genet Med. Author manuscript; available in PMC 2022 May 3.

Published in final edited form as: Genet Med. 2020 Mar; 22(3): 524–537. Published online 2019 Oct 3. doi: 10.1038/s41436-019-0657-0

PMCID:: PMC9063678

Abstract Article PDF–1.5M

Select item 88288956.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 74254718.

MicroRNA-15a/16/SOX5 axis promotes migration, invasion and inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes

Hua Wei, Qin Wu, Yumeng Shi, Aishu Luo, Shiyu Lin, Xiaoke Feng, Jintao Jiang, Miaojia Zhang, Fang Wang, Wenfeng Tan

Aging (Albany NY) 2020 Jul 31; 12(14): 14376–14390. Published online 2020 Jul 17. doi: 10.18632/aging.103480

PMCID:: PMC7425471

Abstract Article PDF–2.0M

Select item 73505579.

Transactivation of SOX5 by Brachyury promotes breast cancer bone metastasis

Ming Chen, Shitao Zou, Chao He, Jundong Zhou, Suoyuan Li, Minghong Shen, Rulei Cheng, Donglai Wang, Tianming Zou, Xueqi Yan, Ying Huang, Jun Shen

Carcinogenesis. 2020 Jul; 41(5): 551–560. Published online 2019 Nov 12. doi: 10.1093/carcin/bgz142

PMCID:: PMC7350557

Abstract Article PDF–91M

Select item 733940510.

High expression levels and localization of Sox5 in dilated cardiomyopathy

Yafeng Liu, Ben Jiang, Yide Cao, Wen Chen, Li Yin, Yueyue Xu, Zhibing Qiu

Mol Med Rep. 2020 Aug; 22(2): 948–956. Published online 2020 May 22. doi: 10.3892/mmr.2020.11180

PMCID:: PMC7339405

Abstract Article PDF–1.0M

Select item 716998311.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 677813712.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 674264613.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 669119314.

MicroRNA-539 inhibits the proliferation and migration of gastric cancer cells by targeting SRY-box 5 gene

Shi Ding, Yanping Zhang

Mol Med Rep. 2019 Sep; 20(3): 2533–2540. Published online 2019 Jul 11. doi: 10.3892/mmr.2019.10486

PMCID:: PMC6691193

Abstract Article PDF–1.2M

Select item 666896815.

Circular RNA DOCK1 promotes bladder carcinoma progression via modulating circDOCK1/hsa‐miR‐132‐3p/Sox5 signalling pathway

Peihua Liu, Xiaozhou Li, Xi Guo, Jinbo Chen, Chao Li, Minfeng Chen, Longfei Liu, Xiangyang Zhang, Xiongbing Zu

Cell Prolif. 2019 Jul; 52(4): e12614. Published online 2019 Apr 14. doi: 10.1111/cpr.12614

PMCID:: PMC6668968

Abstract Article PDF–2.4M

Select item 650501716.

PEX10, SIRPA-SIRPG, and SOX5 gene polymorphisms are strongly associated with nonobstructive azoospermia susceptibility

Xiuli Gu, Honggang Li, Xi Chen, Xue Zhang, Fen Mei, Mingzhu Jia, Chengliang Xiong

J Assist Reprod Genet. 2019 Apr; 36(4): 759–768. Published online 2019 Mar 13. doi: 10.1007/s10815-019-01417-w

PMCID:: PMC6505017

Abstract Article PDF–445K

Select item 615985717.

Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain

Pradeep Suri, Melody R. Palmer, Yakov A. Tsepilov, Maxim B. Freidin, Cindy G. Boer, Michelle S. Yau, Daniel S. Evans, Andrea Gelemanovic, Traci M. Bartz, Maria Nethander, Liubov Arbeeva, Lennart Karssen, Tuhina Neogi, Archie Campbell, Dan Mellstrom, Claes Ohlsson, Lynn M. Marshall, Eric Orwoll, Andre Uitterlinden, Jerome I. Rotter, Gordan Lauc, Bruce M. Psaty, Magnus K. Karlsson, Nancy E. Lane, Gail P. Jarvik, Ozren Polasek, Marc Hochberg, Joanne M. Jordan, Joyce B. J. Van Meurs, Rebecca Jackson, Carrie M. Nielson, Braxton D. Mitchell, Blair H. Smith, Caroline Hayward, Nicholas L. Smith, Yurii S. Aulchenko, Frances M. K. Williams

PLoS Genet. 2018 Sep; 14(9): e1007601. Published online 2018 Sep 27. doi: 10.1371/journal.pgen.1007601

PMCID:: PMC6159857

Abstract Article PDF–1.6M

Select item 607546318.

Silencing of the Drosophila ortholog of SOX5 leads to abnormal neuronal development and behavioral impairment

Airong Li, Basavaraj Hooli, Kristina Mullin, Rebecca E. Tate, Adele Bubnys, Rory Kirchner, Brad Chapman, Oliver Hofmann, Winston Hide, Rudolph E. Tanzi

Hum Mol Genet. 2017 Apr 15; 26(8): 1472–1482. Published online 2017 Feb 10. doi: 10.1093/hmg/ddx051

PMCID:: PMC6075463

Abstract Article PDF–712K

Select item 603024519.

TNF-α-Induced SOX5 Upregulation Is Involved in the Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells Through KLF4 Signal Pathway

Lijun Xu, Lili Zheng, Zhifang Wang, Chong Li, Shan Li, Xuedi Xia, Pengyan Zhang, Li Li, Lixia Zhang

Mol Cells. 2018 Jun 30; 41(6): 575–581. Published online 2018 Jun 12. doi: 10.14348/molcells.2018.2359

PMCID:: PMC6030245

Abstract Article PDF–750K

Select item 575610020.

Psychiatric Genomics: An Update and an Agenda

Patrick F Sullivan, Arpana Agrawal, Cynthia M Bulik, Ole A Andreassen, Anders D Børglum, Gerome Breen, Sven Cichon, Howard J Edenberg, Stephen V Faraone, Joel Gelernter, Carol A Mathews, Caroline M Nievergelt, Jordan W Smoller, Michael C O’Donovan, for the Psychiatric Genomics Consortium

Am J Psychiatry. Author manuscript; available in PMC 2018 Jul 1.

Published in final edited form as: Am J Psychiatry. 2018 Jan 1; 175(1): 15–27. Published online 2017 Oct 3. doi: 10.1176/appi.ajp.2017.17030283

PMCID:: PMC5756100

Abstract Article PDF–1.7M

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