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Select item 107863921.

AGO2-RIP-Seq reveals miR-34/miR-449 cluster targetome in sinonasal cancers

Marco Tomasetti, Federica Monaco, Corrado Rubini, Marzia Rossato, Concetta De Quattro, Cristina Beltrami, Giacomo Sollini, Ernesto Pasquini, Monica Amati, Gaia Goteri, Lory Santarelli, Massimo Re

PLoS One. 2024; 19(1): e0295997. Published online 2024 Jan 12. doi: 10.1371/journal.pone.0295997

PMCID:: PMC10786392

Abstract Article PDF–2.3M

Select item 92929732.

MiRNome analysis identifying miR‐205 and miR‐449a as biomarkers of disease progression in intestinal‐type sinonasal adenocarcinoma

Massimo Re, Marco Tomasetti, Federica Monaco, Monica Amati, Corrado Rubini, Giacomo Sollini, Arisa Bajraktari, Federico Maria Gioacchini, Lory Santarelli, Ernesto Pasquini

Head Neck. 2022 Jan; 44(1): 18–33. Published online 2021 Oct 14. doi: 10.1002/hed.26894

PMCID:: PMC9292973

Abstract Article PDF–3.1M

Select item 91023083.

MicroRNA-449a Inhibits Triple Negative Breast Cancer by Disturbing DNA Repair and Chromatid Separation

Beate Vajen, Rahul Bhowmick, Luisa Greiwe, Vera Schäffer, Marlies Eilers, Thea Reinkens, Amelie Stalke, Gunnar Schmidt, Jan Fiedler, Thomas Thum, David S. DeLuca, Ian D. Hickson, Brigitte Schlegelberger, Thomas Illig, Britta Skawran

Int J Mol Sci. 2022 May; 23(9): 5131. Published online 2022 May 4. doi: 10.3390/ijms23095131

PMCID:: PMC9102308

Abstract Article PDF–2.4M

Select item 89740524.

Circular RNA CDK6 suppresses cervical cancer proliferation and metastasis by sponging miR-449a

Peilin Zhong, Aihua Guo, Linhua Wang, Xiurong Lin, Mei Feng

Bioengineered. 2022; 13(3): 4885–4897. Published online 2022 Feb 13. doi: 10.1080/21655979.2022.2036898

PMCID:: PMC8974052

Abstract Article PDF–4.1M

Select item 89736105.

Silencing of long chain noncoding RNA paternally expressed gene (PEG10) inhibits the progression of neuroblastoma by regulating microRNA-449a (miR-449a)/ribosomal protein S2 (RPS2) axis

Jian Zhang, Wei Liu, Ping Ji, Yan Zhang

Bioengineered. 2022; 13(3): 6309–6322. Published online 2022 Feb 25. doi: 10.1080/21655979.2022.2042999

PMCID:: PMC8973610

Abstract Article PDF–3.5M

Select item 81574366.

MicroRNA-449a delays lung cancer development through inhibiting KDM3A/HIF-1α axis

Shan Hu, Peng Cao, Kangle Kong, Peng Han, Yu Deng, Fan Li, Bo Zhao

J Transl Med. 2021; 19: 224. Published online 2021 May 27. doi: 10.1186/s12967-021-02881-8

PMCID:: PMC8157436

Abstract Article PDF–3.4M

Select item 78639117.

Dysregulation of hsa-miR-34a and hsa-miR-449a leads to overexpression of PACS-1 and loss of DNA damage response (DDR) in cervical cancer

Mysore S. Veena, Santanu Raychaudhuri, Saroj K. Basak, Natarajan Venkatesan, Parameet Kumar, Roopa Biswas, Rita Chakrabarti, Jing Lu, Trent Su, Marcus Gallagher-Jones, Marco Morselli, Haiqing Fu, Matteo Pellegrini, Theodore Goldstein, Mirit I. Aladjem, Matthew B. Rettig, Sharon P. Wilczynski, Daniel Sanghoon Shin, Eri S. Srivatsan

J Biol Chem. 2020 Dec 11; 295(50): 17169–17186. Published online 2020 Oct 7. doi: 10.1074/jbc.RA120.014048

PMCID:: PMC7863911

Abstract Article PDF–6.4M

Select item 78484038.

miR-449a Suppresses Tumor Growth, Migration, and Invasion in Non-Small Cell Lung Cancer by Targeting a HMGB1-Mediated NF-κB Signaling Pathway

Dandan Wu, Jun Liu, Jianliang Chen, Haiyan He, Hang Ma, Xuedong Lv

Oncol Res. 2019; 27(2): 227–235. Published online 2019 Feb 5. doi: 10.3727/096504018X15213089759999

PMCID:: PMC7848403

Abstract Article PDF–16M

Select item 78099029.

Melatonin inhibits proliferation and viability and promotes apoptosis in colorectal cancer cells via upregulation of the microRNA-34a/449a cluster

Guangyu Ji, Wenjuan Zhou, Xian Li, Jingyi Du, Xinyue Li, Hongbo Hao

Mol Med Rep. 2021 Mar; 23(3): 187. Published online 2021 Jan 5. doi: 10.3892/mmr.2021.11826

PMCID:: PMC7809902

Abstract Article PDF–11M

Select item 779524210.

S-Adenosylmethionine Inhibits Cell Growth and Migration of Triple Negative Breast Cancer Cells through Upregulating MiRNA-34c and MiRNA-449a

Alessandra Coppola, Concetta Paola Ilisso, Antonietta Stellavato, Chiara Schiraldi, Michele Caraglia, Laura Mosca, Giovanna Cacciapuoti, Marina Porcelli

Int J Mol Sci. 2021 Jan; 22(1): 286. Published online 2020 Dec 30. doi: 10.3390/ijms22010286

PMCID:: PMC7795242

Abstract Article PDF–2.2M

Select item 778041411.

CDK13 upregulation-induced formation of the positive feedback loop among circCDK13, miR-212-5p/miR-449a and E2F5 contributes to prostate carcinogenesis

Jin-Chun Qi, Zhan Yang, Tao Lin, Long Ma, Ya-Xuan Wang, Yong Zhang, Chun-Cheng Gao, Kai-Long Liu, Wei Li, An-Ning Zhao, Bei Shi, Hong Zhang, Dan-Dan Wang, Xiao-Lu Wang, Jin-Kun Wen, Chang-Bao Qu

J Exp Clin Cancer Res. 2021; 40: 2. Published online 2021 Jan 4. doi: 10.1186/s13046-020-01814-5

PMCID:: PMC7780414

Abstract Article PDF–4.0M

Select item 749423312.

LncRNA SNHG4 Attenuates Inflammatory Responses by Sponging miR-449c-5p and Up-Regulating STAT6 in Microglial During Cerebral Ischemia-Reperfusion Injury

Shuo Zhang, Wen-chong Sun, Zuo-di Liang, Xiu-ru Yin, Zhen-rong Ji, Xiao-huan Chen, Min-jie Wei, Ling Pei

Drug Des Devel Ther. 2020; 14: 3683–3695. Published online 2020 Sep 11. doi: 10.2147/DDDT.S245445

PMCID:: PMC7494233

Abstract Article PDF–6.2M

Select item 743234613.

Role of miR-96/EVI1/miR-449a Axis in the Nasopharyngeal Carcinoma Cell Migration and Tumor Sphere Formation

Lai-Sheung Chan, Hong-Lok Lung, Roger Kai-Cheong Ngan, Anne Wing-Mui Lee, Sai Wah Tsao, Kwok-Wai Lo, Michael Kahn, Maria Li Lung, Rotraud Wieser, Nai-Ki Mak

Int J Mol Sci. 2020 Aug; 21(15): 5495. Published online 2020 Jul 31. doi: 10.3390/ijms21155495