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Items: 1 to 20 of 33

1.
Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification
Camila M. Aprosoff, Boris J.A. Dyakov, Vivian H.W. Cheung, Cassandra J. Wong, Mikaela Palandra, Anne-Claude Gingras, Haley D.M. Wyatt
J Proteome Res. 2023 Jun 2; 22(6): 1660–1681. Published online 2023 Apr 18. doi: 10.1021/acs.jproteome.2c00706
PMCID:
PMC10243116
AbstractArticlePDF–13M
2.
Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling
Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser
Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151
PMCID:
PMC9105235
AbstractArticlePDF–5.8M
3.
PCNA activates the MutLγ endonuclease to promote meiotic crossing over
Dhananjaya S. Kulkarni, Shannon N. Owens, Masayoshi Honda, Masaru Ito, Ye Yang, Mary W. Corrigan, Lan Chen, Aric L. Quan, Neil Hunter
Nature. Author manuscript; available in PMC 2021 Jul 16.
Published in final edited form as: Nature. 2020 Oct; 586(7830): 623–627. Published online 2020 Aug 19. doi: 10.1038/s41586-020-2645-6
Correction in:
Nature. 2021 Jan 19
PMCID:
PMC8284803
AbstractArticlePDF–4.8M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Genetic evidence for the involvement of mismatch repair proteins, PMS2 and MLH3, in a late step of homologous recombination
Md Maminur Rahman, Mohiuddin Mohiuddin, Islam Shamima Keka, Kousei Yamada, Masataka Tsuda, Hiroyuki Sasanuma, Jessica Andreani, Raphael Guerois, Valerie Borde, Jean-Baptiste Charbonnier, Shunichi Takeda
J Biol Chem. 2020 Dec 18; 295(51): 17460–17475. Published online 2020 Oct 2. doi: 10.1074/jbc.RA120.013521
PMCID:
PMC7762965
AbstractArticlePDF–2.9M
6.
Human MutLγ, the MLH1–MLH3 heterodimer, is an endonuclease that promotes DNA expansion
Lyudmila Y. Kadyrova, Vaibhavi Gujar, Vickers Burdett, Paul L. Modrich, Farid A. Kadyrov
Proc Natl Acad Sci U S A. 2020 Feb 18; 117(7): 3535–3542. Published online 2020 Feb 3. doi: 10.1073/pnas.1914718117
PMCID:
PMC7035508
AbstractArticlePDF–1.1M
7.
Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity
Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller
Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119
PMCID:
PMC6942044
AbstractArticlePDF–10M
8.
Biallelic germline nonsense variant of MLH3 underlies polyposis predisposition
Alisa Olkinuora, Taina T. Nieminen, Emma Mårtensson, Anna Rohlin, Ari Ristimäki, Laura Koskenvuo, Anna Lepistö, Swedish Extended Genetic Analysis of Colorectal Neoplasia (SWEN) Study Group, Samuel Gebre-Medhin, Margareta Nordling, Päivi Peltomäki
Genet Med. 2019; 21(8): 1868–1873. Published online 2018 Dec 21. doi: 10.1038/s41436-018-0405-x
PMCID:
PMC6752675
AbstractArticlePDF–596K
9.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
10.
GAA•TTC repeat expansion in human cells is mediated by mismatch repair complex MutLγ and depends upon the endonuclease domain in MLH3 isoform one
Anasheh Halabi, Kayla T B Fuselier, Ed Grabczyk
Nucleic Acids Res. 2018 May 4; 46(8): 4022–4032. Published online 2018 Feb 26. doi: 10.1093/nar/gky143
PMCID:
PMC5934671
AbstractArticlePDF–2.6M
11.
Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients
Andrea Mann, Estrid Hogdall, Susan J. Ramus, Richard A. DiCioccio, Claus Hogdall, Lydia Quaye, Valerie McGuire, Alice S. Whittemore, Mitul Shah, David Greenberg, Douglas F. Easton, Bruce A.J. Ponder, Susanne Krüger Kjaer, Simon A. Gayther, Deborah J. Thompson, Paul D.P. Pharoah, Honglin Song
Eur J Cancer. Author manuscript; available in PMC 2017 Sep 21.
Published in final edited form as: Eur J Cancer. 2008 Oct; 44(15): 2259–2265. Published online 2008 Aug 22. doi: 10.1016/j.ejca.2008.07.010
PMCID:
PMC5608075
AbstractArticlePDF–312K
12.
Functional Screening of FxxLF-Like Peptide Motifs Identifies SMARCD1/BAF60a as an Androgen Receptor Cofactor that Modulates TMPRSS2 Expression
Dennis J. van de Wijngaart, Hendrikus J. Dubbink, Michel Molier, Carola de Vos, Jan Trapman, Guido Jenster
Mol Endocrinol. November 1, 2009; 23(11): 1776–1786. doi: 10.1210/me.2008-0280
PMCID:
PMC5419170
AbstractArticle
13.
Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor
Sarah Daakour, Leon Juvenal Hajingabo, Despoina Kerselidou, Aurelie Devresse, Richard Kettmann, Nicolas Simonis, Franck Dequiedt, Jean-Claude Twizere
BMC Cancer. 2016; 16: 335. Published online 2016 May 26. doi: 10.1186/s12885-016-2374-2
PMCID:
PMC4882867
AbstractArticlePDF–1.8M
14.
Single-nucleotide polymorphism rs 175080 in the MLH3 gene and its relation to male infertility
Ourania Markandona, Konstantinos Dafopoulos, George Anifandis, Christina I. Messini, Marina. Dimitraki, Aspasia Tsezou, Panagiotis Georgoulias, Ioannis E. Messinis
J Assist Reprod Genet. 2015 Dec; 32(12): 1795–1799. Published online 2015 Oct 31. doi: 10.1007/s10815-015-0594-z
PMCID:
PMC4681734
AbstractArticlePDF–553K
15.
Mutation screening of mismatch repair gene Mlh3 in familial esophageal cancer
Hong-Xu Liu, Yu Li, Xue-Dong Jiang, Hong-Nian Yin, Lin Zhang, Yu Wang, Jun Yang
World J Gastroenterol. 2006 Sep 7; 12(33): 5281–5286. Published online 2006 Sep 7. doi: 10.3748/wjg.v12.i33.5281
PMCID:
PMC4088192
AbstractArticlePDF–795K
16.
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease
Stefanie L. Butland, Shaun S. Sanders, Mandi E. Schmidt, Sean-Patrick Riechers, David T.S. Lin, Dale D.O. Martin, Kuljeet Vaid, Rona K. Graham, Roshni R. Singaraja, Erich E. Wanker, Elizabeth Conibear, Michael R. Hayden
Hum Mol Genet. 2014 Aug 1; 23(15): 4142–4160. Published online 2014 Apr 4. doi: 10.1093/hmg/ddu137
PMCID:
PMC4082372
AbstractArticlePDF–1.7M
17.
Mismatch Repair Gene MLH3 Pro844Leu and Thr942Ile Polymorphisms and the Susceptibility to Cervical Carcinoma and HPV Infection: A Case-Control Study in a Chinese Population
Feng Ye, Qi Cheng, Jiajie Shen, Caiyun Zhou, Huaizeng Chen
PLoS One. 2014; 9(4): e96224. Published online 2014 Apr 23. doi: 10.1371/journal.pone.0096224
PMCID:
PMC3997526
AbstractArticlePDF–441K
18.
The Saccharomyces cerevisiae Mlh1-Mlh3 Heterodimer Is an Endonuclease That Preferentially Binds to Holliday Junctions
Lepakshi Ranjha, Roopesh Anand, Petr Cejka
J Biol Chem. 2014 Feb 28; 289(9): 5674–5686. Published online 2014 Jan 17. doi: 10.1074/jbc.M113.533810
PMCID:
PMC3937642
AbstractArticlePDF–3.0M
19.
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins, Stephan Ripke, Rinse K Weersma, Richard H Duerr, Dermot P McGovern, Ken Y Hui, James C Lee, L Philip Schumm, Yashoda Sharma, Carl A Anderson, Jonah Essers, Mitja Mitrovic, Kaida Ning, Isabelle Cleynen, Emilie Theatre, Sarah L Spain, Soumya Raychaudhuri, Philippe Goyette, Zhi Wei, Clara Abraham, Jean-Paul Achkar, Tariq Ahmad, Leila Amininejad, Ashwin N Ananthakrishnan, Vibeke Andersen, Jane M Andrews, Leonard Baidoo, Tobias Balschun, Peter A Bampton, Alain Bitton, Gabrielle Boucher, Stephan Brand, Carsten Büning, Ariella Cohain, Sven Cichon, Mauro D’Amato, Dirk De Jong, Kathy L Devaney, Marla Dubinsky, Cathryn Edwards, David Ellinghaus, Lynnette R Ferguson, Denis Franchimont, Karin Fransen, Richard Gearry, Michel Georges, Christian Gieger, Jürgen Glas, Talin Haritunians, Ailsa Hart, Chris Hawkey, Matija Hedl, Xinli Hu, Tom H Karlsen, Limas Kupcinskas, Subra Kugathasan, Anna Latiano, Debby Laukens, Ian C Lawrance, Charlie W Lees, Edouard Louis, Gillian Mahy, John Mansfield, Angharad R Morgan, Craig Mowat, William Newman, Orazio Palmieri, Cyriel Y Ponsioen, Uros Potocnik, Natalie J Prescott, Miguel Regueiro, Jerome I Rotter, Richard K Russell, Jeremy D Sanderson, Miquel Sans, Jack Satsangi, Stefan Schreiber, Lisa A Simms, Jurgita Sventoraityte, Stephan R Targan, Kent D Taylor, Mark Tremelling, Hein W Verspaget, Martine De Vos, Cisca Wijmenga, David C Wilson, Juliane Winkelmann, Ramnik J Xavier, Sebastian Zeissig, Bin Zhang, Clarence K Zhang, Hongyu Zhao, The International IBD Genetics Consortium, Mark S Silverberg, Vito Annese, Hakon Hakonarson, Steven R Brant, Graham Radford-Smith, Christopher G Mathew, John D Rioux, Eric E Schadt, Mark J Daly, Andre Franke, Miles Parkes, Severine Vermeire, Jeffrey C Barrett, Judy H Cho
Nature. Author manuscript; available in PMC 2013 May 1.
Published in final edited form as: Nature. 2012 Nov 1; 491(7422): 119–124. doi: 10.1038/nature11582
PMCID:
PMC3491803
AbstractArticlePDF–706K
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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