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Select item 112110201.

Dominant role for pigment epithelial CRALBP in supplying visual chromophore to photoreceptors

Marco Bassetto, Alexander V. Kolesnikov, Dominik Lewandowski, Jianying Z. Kiser, Maximilian Halabi, David E. Einstein, Elliot H. Choi, Krzysztof Palczewski, Vladimir J. Kefalov, Philip D. Kiser

Cell Rep. Author manuscript; available in PMC 2024 Jun 27.

Published in final edited form as: Cell Rep. 2024 May 28; 43(5): 114143. Published online 2024 Apr 25. doi: 10.1016/j.celrep.2024.114143

PMCID:: PMC11211020

Abstract Article PDF–1.8M

Select item 111057702.

Bardet–Biedl Syndrome proteins regulate cilia disassembly during tissue maturation

Sarita Rani Patnaik, Viola Kretschmer, Lena Brücker, Sandra Schneider, Ann-Kathrin Volz, Liliana del Rocio Oancea-Castillo, Helen Louise May-Simera

Cell Mol Life Sci. 2019 Feb; 76(4): 757–775. Published online 2018 Nov 16. doi: 10.1007/s00018-018-2966-x

PMCID:: PMC11105770

Abstract Article PDF–3.0M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107562124.

A simple, rapid fluorescent reporter-based method for detection of ectopic Cre recombinase expression in presumed retinal cell type-targeted mouse lines

Sriganesh Ramachandra Rao, Steven J. Fliesler

Exp Eye Res. Author manuscript; available in PMC 2023 Dec 29.

Published in final edited form as: Exp Eye Res. 2023 Oct; 235: 109637. Published online 2023 Aug 31. doi: 10.1016/j.exer.2023.109637

PMCID:: PMC10756212

Abstract Article PDF–1.3M

Select item 105304945.

Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia

Aleksander Tworak, Alexander V. Kolesnikov, John D. Hong, Elliot H. Choi, Jennings C. Luu, Grazyna Palczewska, Zhiqian Dong, Dominik Lewandowski, Matthew J. Brooks, Laura Campello, Anand Swaroop, Philip D. Kiser, Vladimir J. Kefalov, Krzysztof Palczewski

Cell Rep. Author manuscript; available in PMC 2023 Sep 27.

Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112982. Published online 2023 Aug 15. doi: 10.1016/j.celrep.2023.112982

PMCID:: PMC10530494

Abstract Article PDF–3.2M

Select item 103547296.

Gene Supplementation in Mice Heterozygous for the D477G RPE65 Variant Implicated in Autosomal Dominant Retinitis Pigmentosa

Kecia L. Feathers, Lin Jia, Naheed W. Khan, Alexander J. Smith, Jian-Xing Ma, Robin R. Ali, Debra A. Thompson

Hum Gene Ther. July 2023; 34(13-14): 639–648. Published online 2023 Jul 17. doi: 10.1089/hum.2022.240

PMCID:: PMC10354729

Abstract Article PDF–956K

Select item 102660387.

Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models

Yunlu Xue, Xiaomei Sun, Sean K. Wang, Gayle B. Collin, Vladimir J. Kefalov, Constance L. Cepko

Proc Natl Acad Sci U S A. 2023 Jun 6; 120(23): e2217885120. Published online 2023 May 30. doi: 10.1073/pnas.2217885120

PMCID:: PMC10266038

Abstract Article PDF–5.5M

Select item 101742928.

Mouse all-cone retina models of Cav1.4 synaptopathy

Joseph G. Laird, Ariel Kopel, Colten K. Lankford, Sheila A. Baker

Front Mol Neurosci. 2023; 16: 1155955. Published online 2023 Apr 27. doi: 10.3389/fnmol.2023.1155955

PMCID:: PMC10174292

Abstract Article PDF–2.8M

Select item 99187199.

Galanin receptor 3 - a new pharmacological target in retina degeneration

Joseph T. Ortega, Tanu Parmar, Beata Jastrzebska

Pharmacol Res. Author manuscript; available in PMC 2024 Feb 1.

Published in final edited form as: Pharmacol Res. 2023 Jan 21; 188: 106675. Published online 2023 Jan 21. doi: 10.1016/j.phrs.2023.106675

PMCID:: PMC9918719

Abstract Article PDF–2.8M

Select item 898373410.

In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration

Elliot H. Choi, Susie Suh, Andrzej T. Foik, Henri Leinonen, Gregory A. Newby, Xin D. Gao, Samagya Banskota, Thanh Hoang, Samuel W. Du, Zhiqian Dong, Aditya Raguram, Sajeev Kohli, Seth Blackshaw, David C. Lyon, David R. Liu, Krzysztof Palczewski

Nat Commun. 2022; 13: 1830. Published online 2022 Apr 5. doi: 10.1038/s41467-022-29490-3

PMCID:: PMC8983734

Abstract Article PDF–5.7M

Select item 893121211.

The interplay of environmental luminance and genetics in the retinal dystrophy induced by the dominant RPE65 mutation

Wenjing Wu, Yusuke Takahashi, Henry Younghwa Shin, Xiang Ma, Gennadiy Moiseyev, Jian-Xing Ma

Proc Natl Acad Sci U S A. 2022 Mar 15; 119(11): e2115202119. Published online 2022 Mar 10. doi: 10.1073/pnas.2115202119

PMCID:: PMC8931212

Abstract Article PDF–2.6M

Select item 875979512.

In vivo imaging of the human eye using a 2-photon-excited fluorescence scanning laser ophthalmoscope

Jakub Boguslawski, Grazyna Palczewska, Slawomir Tomczewski, Jadwiga Milkiewicz, Piotr Kasprzycki, Dorota Stachowiak, Katarzyna Komar, Marcin J. Marzejon, Bartosz L. Sikorski, Arkadiusz Hudzikowski, Aleksander Głuszek, Zbigniew Łaszczych, Karol Karnowski, Grzegorz Soboń, Krzysztof Palczewski, Maciej Wojtkowski

J Clin Invest. 2022 Jan 18; 132(2): e154218. Published online 2022 Jan 18. doi: 10.1172/JCI154218

PMCID:: PMC8759795

Abstract Article PDF–1.7M

Select item 857784913.

mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia

Soyeon Lim, You-Joung Kim, Sooyeon Park, Ji-heon Choi, Young Hoon Sung, Katsuhiko Nishimori, Zbynek Kozmik, Han-Woong Lee, Jin Woo Kim

eLife. 2021; 10: e70079. Published online 2021 Oct 22. doi: 10.7554/eLife.70079

PMCID:: PMC8577849

Abstract Article PDF–10M

Select item 826234314.

An inducible Cre mouse for studying roles of the RPE in retinal physiology and disease

Elliot H. Choi, Susie Suh, David E. Einstein, Henri Leinonen, Zhiqian Dong, Sriganesh Ramachandra Rao, Steven J. Fliesler, Seth Blackshaw, Minzhong Yu, Neal S. Peachey, Krzysztof Palczewski, Philip D. Kiser

JCI Insight. 2021 May 10; 6(9): e146604. Published online 2021 May 10. doi: 10.1172/jci.insight.146604

PMCID:: PMC8262343

Abstract Article PDF–11M

Select item 801959615.

Tsg101 Is Necessary for the Establishment and Maintenance of Mouse Retinal Pigment Epithelial Cell Polarity

Dai Le, Soyeon Lim, Kwang Wook Min, Joon Woo Park, Youjoung Kim, Taejeong Ha, Kyeong Hwan Moon, Kay-Uwe Wagner, Jin Woo Kim

Mol Cells. 2021 Mar 31; 44(3): 168–178. Published online 2021 Mar 28. doi: 10.14348/molcells.2021.0027

PMCID:: PMC8019596

Abstract Article PDF–34M

Select item 793698316.

Prolonged melanopsin-based photoresponses depend in part on RPE65 and cellular retinaldehyde-binding protein (CRALBP)

Krystal R. Harrison, Aaron N. Reifler, Andrew P. Chervenak, Kwoon Y. Wong

Curr Eye Res. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: Curr Eye Res. 2021 Apr; 46(4): 515–523. Published online 2020 Sep 7. doi: 10.1080/02713683.2020.1815793

PMCID:: PMC7936983

Abstract Article PDF–1.2M

Select item 789166317.

A Comparative Analysis of Reactive Müller Glia Gene Expression After Light Damage and microRNA-Depleted Müller Glia—Focus on microRNAs

Seoyoung Kang, Daniel Larbi, Monica Andrade, Sara Reardon, Thomas A. Reh, Stefanie G. Wohl

Front Cell Dev Biol. 2020; 8: 620459. Published online 2021 Jan 26. doi: 10.3389/fcell.2020.620459

PMCID:: PMC7891663

Abstract Article PDF–4.9M

Select item 782026118.

A new mouse model for retinal degeneration due to Fam161a deficiency

Avigail Beryozkin, Chen Matsevich, Alexey Obolensky, Corinne Kostic, Yvan Arsenijevic, Uwe Wolfrum, Eyal Banin, Dror Sharon

Sci Rep. 2021; 11: 2030. Published online 2021 Jan 21. doi: 10.1038/s41598-021-81414-1

PMCID:: PMC7820261

Abstract Article PDF–3.3M

Select item 774932519.

Inverse correlation between fatty acid transport protein 4 and vision in Leber congenital amaurosis associated with RPE65 mutation

Songhua Li, William C. Gordon, Nicolas G. Bazan, Minghao Jin

Proc Natl Acad Sci U S A. 2020 Dec 15; 117(50): 32114–32123. Published online 2020 Nov 30. doi: 10.1073/pnas.2012623117

PMCID:: PMC7749325

Abstract Article PDF–2.2M

Select item 772583920.

Renin–angiotensin system impairs macrophage lipid metabolism to promote age-related macular degeneration in mouse models

Norihiro Nagai, Hirohiko Kawashima, Eriko Toda, Kohei Homma, Hideto Osada, Naymel A. Guzman, Shinsuke Shibata, Yasuo Uchiyama, Hideyuki Okano, Kazuo Tsubota, Yoko Ozawa

Commun Biol. 2020; 3: 767. Published online 2020 Dec 9. doi: 10.1038/s42003-020-01483-2

PMCID:: PMC7725839

Abstract Article PDF–3.5M

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