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Items: 1 to 20 of 335

1.
Interaction of antiproliferative protein Tob with the CCR4‐NOT deadenylase complex
Takashi Miyasaka, Masahiro Morita, Kentaro Ito, Toru Suzuki, Hiroyuki Fukuda, Shizu Takeda, Jun‐Ichiro Inoue, Kentaro Semba, Tadashi Yamamoto
Cancer Sci. 2008 Apr; 99(4): 755–761. Published online 2008 Mar 28. doi: 10.1111/j.1349-7006.2008.00746.x
PMCID:
PMC11158977
AbstractArticlePDF–210K
2.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
PMCID:
PMC11148184
AbstractArticlePDF–8.1M
3.
TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence
Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang
Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6
PMCID:
PMC10764958
AbstractArticlePDF–4.4M
4.
AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer
Wenwen Tian, Yuhui Tang, Yongzhou Luo, Jindong Xie, Shaoquan Zheng, Yutian Zou, Xiaojia Huang, Linyu Wu, Junsheng Zhang, Yuying Sun, Hailin Tang, Wei Du, Xing Li, Xiaoming Xie
Cell Death Dis. 2023 Dec; 14(12): 790. Published online 2023 Dec 1. doi: 10.1038/s41419-023-06115-1
PMCID:
PMC10692340
AbstractArticlePDF–5.0M
5.
The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg
Science. Author manuscript; available in PMC 2023 Oct 31.
Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021
PMCID:
PMC10617673
AbstractArticlePDF–3.6M
6.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
7.
P68 RNA Helicase (DDX5) Required for the Formation of Various Specific and Mature miRNA Active RISC Complexes
Mariette Kokolo, Montse Bach-Elias
Microrna. 2022 Jul 29; 11(1): 36–44. Published online 2022 Jul 29. doi: 10.2174/2211536611666220218121640
PMCID:
PMC10556402
AbstractArticlePDF–3.0M
8.
Role of the DEAD-box RNA helicase DDX5 (p68) in cancer DNA repair, immune suppression, cancer metabolic control, virus infection promotion, and human microbiome (microbiota) negative influence
Fengzhi Li, Xiang Ling, Sayan Chakraborty, Christos Fountzilas, Jianmin Wang, Anmbreen Jamroze, Xiaozhuo Liu, Pawel Kalinski, Dean G. Tang
J Exp Clin Cancer Res. 2023; 42: 213. Published online 2023 Aug 19. doi: 10.1186/s13046-023-02787-x
PMCID:
PMC10439624
AbstractArticlePDF–3.3M
9.
Hypoxia‐mediated regulation of DDX5 through decreased chromatin accessibility and post‐translational targeting restricts R‐loop accumulation
Katarzyna B. Leszczynska, Monika Dzwigonska, Hala Estephan, Jutta Moehlenbrink, Elizabeth Bowler, Amato J. Giaccia, Jakub Mieczkowski, Bozena Kaminska, Ester M. Hammond
Mol Oncol. 2023 Jul; 17(7): 1173–1191. Published online 2023 Apr 22. doi: 10.1002/1878-0261.13431
PMCID:
PMC10323886
AbstractArticlePDF–2.6M
10.
Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry
Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang
Anal Chem. Author manuscript; available in PMC 2023 Jun 21.
Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986
PMCID:
PMC10284117
AbstractArticlePDF–2.5M
11.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
12.
The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing
Yingxiao Chen, Yanping Li, Roselyn S Dai, Jonathan C Savage, Ujwal Shinde, John Klimek, Larry L David, Emma A Young, Markus Hafner, Rosalie C Sears, Xiao-Xin Sun, Mu-Shui Dai
Nucleic Acids Res. 2023 May 8; 51(8): 3934–3949. Published online 2023 Mar 13. doi: 10.1093/nar/gkad140
PMCID:
PMC10164564
AbstractArticlePDF–3.8M
13.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
14.
Study of FOXO1-interacting proteins using TurboID-based proximity labeling technology
Yanting Su, Yuanyuan Guo, Jieyu Guo, Ting Zeng, Ting Wang, Wu Liu
BMC Genomics. 2023; 24: 146. Published online 2023 Mar 24. doi: 10.1186/s12864-023-09238-z
PMCID:
PMC10039511
AbstractArticlePDF–2.0M
15.
USP35 promotes cell proliferation and chemotherapeutic resistance through stabilizing FUCA1 in colorectal cancer
Yi Xiao, Xiaoyu Jiang, Ke Yin, Tianshu Miao, Hanlin Lu, Wenqing Wang, Lijuan Ma, Yinghui Zhao, Chunyan Liu, Yun Qiao, Pengju Zhang
Oncogenesis. 2023 Dec; 12(1): 12. Published online 2023 Mar 3. doi: 10.1038/s41389-023-00458-2
PMCID:
PMC9981583
AbstractArticlePDF–3.9M
16.
Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma
Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li
Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x
PMCID:
PMC9950447
AbstractArticlePDF–8.4M
17.
The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain
Lisa Marie Weber, Yulin Jia, Bastian Stielow, Stephen S Gisselbrecht, Yinghua Cao, Yanpeng Ren, Iris Rohner, Jessica King, Elisabeth Rothman, Sabrina Fischer, Clara Simon, Ignasi Forné, Andrea Nist, Thorsten Stiewe, Martha L Bulyk, Zhanxin Wang, Robert Liefke
Nucleic Acids Res. 2023 Jan 25; 51(2): 574–594. Published online 2022 Dec 20. doi: 10.1093/nar/gkac1188
PMCID:
PMC9881136
AbstractArticlePDF–4.4M
18.
Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth
David J. Wisniewski, Mariya S. Liyasova, Soumya Korrapati, Xu Zhang, Shashikala Ratnayake, Qingrong Chen, Samuel F. Gilbert, Alexis Catalano, Donna Voeller, Daoud Meerzaman, Udayan Guha, Natalie Porat-Shliom, Christina M. Annunziata, Stanley Lipkowitz
J Biol Chem. 2023 Jan; 299(1): 102766. Published online 2022 Dec 5. doi: 10.1016/j.jbc.2022.102766
PMCID:
PMC9823131
AbstractArticlePDF–2.5M
19.
TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1
Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel
J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144
PMCID:
PMC9797988
AbstractArticlePDF–6.9M
20.
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia
Qi Jin, Blanca Gutierrez Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Von Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L. Safgren, Yi-Chien Tsai, Beat Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D. Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos
Sci Adv. 2022 Dec; 8(49): eabq8437. Published online 2022 Dec 9. doi: 10.1126/sciadv.abq8437
PMCID:
PMC9733937
AbstractArticlePDF–2.2M

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