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Items: 1 to 20 of 71

1.
A germline SNP in BRMS1 predisposes patients with lung adenocarcinoma to metastasis and can be ameliorated by targeting c-fos
Yuan Liu, Neel Chudgar, Brooke Mastrogiacomo, Di He, Manendra B. Lankadasari, Samhita Bapat, Gregory D. Jones, Francisco Sanchez-Vega, Kay See Tan, Nikolaus Schultz, Semanti Mukherjee, Kenneth Offit, Yongde Bao, Matthew J. Bott, Natasha Rekhtman, Prasad S. Adusumilli, Bob T. Li, Marty W. Mayo, David R. Jones
Sci Transl Med. Author manuscript; available in PMC 2023 Feb 14.
Published in final edited form as: Sci Transl Med. 2022 Oct 5; 14(665): eabo1050. Published online 2022 Oct 5. doi: 10.1126/scitranslmed.abo1050
PMCID:
PMC9926934
AbstractArticlePDF–1.3M
2.
SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk
Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird
Cancer Discov. 2022 Sep 2; 12(9): 2158–2179. Published online 2022 Jul 12. doi: 10.1158/2159-8290.CD-21-0205
PMCID:
PMC9437563
AbstractArticlePDF–9.5M
3.
A Hypoxia-Induced SCFFBXL1 E3 Ligase Ubiquitinates and Degrades the MEN1 Tumor Suppressor to Promote Colorectal Cancer Tumorigenesis
Jun Zeng, Xiao-qing Xiao, Zhi-yong Zhou
Cancer Res Treat. 2022 Apr; 54(2): 525–540. Published online 2021 Jun 29. doi: 10.4143/crt.2021.373
PMCID:
PMC9016320
AbstractArticlePDF–3.0M
4.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner
Lauriane Vélot, Frédéric Lessard, Félix-Antoine Bérubé-Simard, Christophe Tav, Bertrand Neveu, Valentine Teyssier, Imène Boudaoud, Ugo Dionne, Noémie Lavoie, Steve Bilodeau, Frédéric Pouliot, Nicolas Bisson
Mol Cell Proteomics. 2021; 20: 100064. Published online 2021 Feb 26. doi: 10.1016/j.mcpro.2021.100064
PMCID:
PMC8050775
AbstractArticlePDF–3.6M
7.
miR-346 Promotes HCC Progression by Suppressing Breast Cancer Metastasis Suppressor 1 Expression
Zhixian Guo, Jingjing Li, Jihong Sun, Lu Sun, Yubing Zhou, Zujiang Yu
Oncol Res. 2018; 26(7): 1073–1081. Published online 2018 Aug 23. doi: 10.3727/096504017X15145088802439
PMCID:
PMC7844707
AbstractArticlePDF–23M
8.
N6-Methyladenosine modification of the TRIM7 positively regulates tumorigenesis and chemoresistance in osteosarcoma through ubiquitination of BRMS1
Chenliang Zhou, Zhichang Zhang, Xiaoshi Zhu, Guowei Qian, Yan Zhou, Yong Sun, Wenxi Yu, Jiahui Wang, Haiyang Lu, Feng Lin, Zan Shen, Shuier Zheng
EBioMedicine. 2020 Sep; 59: 102955. Published online 2020 Aug 24. doi: 10.1016/j.ebiom.2020.102955
PMCID:
PMC7452680
AbstractArticlePDF–5.1M
9.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
10.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
11.
The isolated C-terminal nuclear localization sequence of the breast cancer metastasis suppressor 1 is disordered
David Pantoja-Uceda, José L. Neira, Lellys M. Contreras, Christa A. Manton, Danny R. Welch, Bruno Rizzuti
Arch Biochem Biophys. Author manuscript; available in PMC 2020 Mar 30.
Published in final edited form as: Arch Biochem Biophys. 2019 Mar 30; 664: 95–101. Published online 2019 Jan 30. doi: 10.1016/j.abb.2019.01.035
PMCID:
PMC6532052
AbstractArticlePDF–940K
12.
H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination in sister chromatids
Kyosuke Nakamura, Giulia Saredi, Jordan R. Becker, Benjamin M. Foster, Nhuong V. Nguyen, Tracey Beyer, Laura C. Cesa, Peter A. Faull, Saulius Lukauskas, Thomas Frimurer, J. Ross Chapman, Till Bartke, Anja Groth
Nat Cell Biol. Author manuscript; available in PMC 2019 Aug 25.
Published in final edited form as: Nat Cell Biol. 2019 Mar; 21(3): 311–318. Published online 2019 Feb 25. doi: 10.1038/s41556-019-0282-9
PMCID:
PMC6420097
ArticlePDF–1.7M
13.
rec-YnH enables simultaneous many-by-many detection of direct protein–protein and protein–RNA interactions
Jae-Seong Yang, Mireia Garriga-Canut, Nele Link, Carlo Carolis, Katrina Broadbent, Violeta Beltran-Sastre, Luis Serrano, Sebastian P. Maurer
Nat Commun. 2018; 9: 3747. Published online 2018 Sep 14. doi: 10.1038/s41467-018-06128-x
PMCID:
PMC6138660
AbstractArticlePDF–1.9M
14.
The tumor suppressor CIC directly regulates MAPK pathway genes via histone deacetylation
Simon Weissmann, Paul A. Cloos, Simone Sidoli, Ole N. Jensen, Steven Pollard, Kristian Helin
Cancer Res. Author manuscript; available in PMC 2019 Feb 1.
Published in final edited form as: Cancer Res. 2018 Aug 1; 78(15): 4114–4125. Published online 2018 May 29. doi: 10.1158/0008-5472.CAN-18-0342
PMCID:
PMC6076439
AbstractArticlePDF–2.5M
15.
The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation
Fabienne Lampert, Diana Stafa, Algera Goga, Martin Varis Soste, Samuel Gilberto, Natacha Olieric, Paola Picotti, Markus Stoffel, Matthias Peter
eLife. 2018; 7: e35528. Published online 2018 Jun 18. doi: 10.7554/eLife.35528
PMCID:
PMC6037477
AbstractArticlePDF–1.5M
16.
MicroRNA-3200-5p Promotes Osteosarcoma Cell Invasion via Suppression of BRMS1
Gen Li, Li Li, Qi Sun, Jiezhou Wu, Wei Ge, Guanghua Lu, Ming Cai
Mol Cells. 2018 Jun 30; 41(6): 523–531. Published online 2018 Jun 11. doi: 10.14348/molcells.2018.2200
PMCID:
PMC6030248
AbstractArticlePDF–3.7M
17.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M
18.
BRMS1 Expression in Surgically Resected Lung Adenocarcinoma Predicts Future Metastases and Is Associated with a Poor Prognosis
Peter R. Bucciarelli, Kay See Tan, Neel P. Chudgar, Whitney Brandt, Joseph Montecalvo, Takashi Eguchi, Yuan Liu, Rania Aly, William D. Travis, Prasad S. Adusumilli, David R. Jones
J Thorac Oncol. Author manuscript; available in PMC 2019 Jan 1.
Published in final edited form as: J Thorac Oncol. 2018 Jan; 13(1): 73–84. Published online 2017 Oct 31. doi: 10.1016/j.jtho.2017.10.006
PMCID:
PMC5738269
AbstractArticlePDF–920K
19.
BRMS1 gene expression may be associated with clinico-pathological features of breast cancer
Li-Zhong Lin, Miao-Guo Cai, Yue-Chu Dai, Zhi-Bao Zheng, Fang-Fang Jiang, Li-Li Shi, Yin Pan, Han-Bing Song
Biosci Rep. 2017 Aug 31; 37(4): BSR20170672. Prepublished online 2017 May 22. Published online 2017 Aug 21. doi: 10.1042/BSR20170672
PMCID:
PMC5563535
AbstractArticlePDF–782K
20.
Fam60a defines a variant Sin3a‐Hdac complex in embryonic stem cells required for self‐renewal
Gundula Streubel, Darren J Fitzpatrick, Giorgio Oliviero, Andrea Scelfo, Bruce Moran, Sudipto Das, Nayla Munawar, Ariane Watson, Kieran Wynne, Gian Luca Negri, Eugene T Dillon, SriGanesh Jammula, Karsten Hokamp, Darran P O'Connor, Diego Pasini, Gerard Cagney, Adrian P Bracken
EMBO J. 2017 Aug 1; 36(15): 2216–2232. Published online 2017 May 29. doi: 10.15252/embj.201696307
PMCID:
PMC5538769
AbstractArticlePDF–1.1M

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