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Select item 100729061.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 99150672.

Identification and characterization of Aurora kinase B and C variants associated with maternal aneuploidy

Alexandra L. Nguyen, Diego Marin, Anbo Zhou, Amanda S. Gentilello, Evan M. Smoak, Zubing Cao, Anastasia Fedick, Yujue Wang, Deanne Taylor, Richard T. Scott, Jr, Jinchuan Xing, Nathan Treff, Karen Schindler

Mol Hum Reprod. 2017 Jun; 23(6): 406–416. Published online 2017 Apr 13. doi: 10.1093/molehr/gax018

PMCID:: PMC9915067

Abstract Article PDF–1.0M

Select item 85005383.

Aurora Kinase mRNA expression is reduced with increasing gestational age and in severe early onset fetal growth restriction

Sally Beard, Natasha Pritchard, Natalie Binder, Karen Schindler, Natasha De Alwis, Tu’uhevaha J. Kaitu’u-Lino, Stephen Tong, Natalie J. Hannan

Placenta. Author manuscript; available in PMC 2021 Oct 8.

Published in final edited form as: Placenta. 2020 Jun; 95: 53–61. Published online 2020 Apr 26. doi: 10.1016/j.placenta.2020.04.012

PMCID:: PMC8500538

Abstract Article PDF–829K

Select item 84082694.

Genetic variations in AURORA cell cycle kinases are associated with glioblastoma multiforme

Aner Mesic, Marija Rogar, Petra Hudler, Nurija Bilalovic, Izet Eminovic, Radovan Komel

Sci Rep. 2021; 11: 17444. Published online 2021 Aug 31. doi: 10.1038/s41598-021-96935-y

PMCID:: PMC8408269

Abstract Article PDF–1.4M

Select item 82669645.

Purging human ovarian cortex of contaminating leukaemic cells by targeting the mitotic catastrophe signalling pathway

Lotte Eijkenboom, Callista Mulder, Bert van der Reijden, Norah van Mello, Julia van Leersum, Thessa Koorenhof-Scheele, Didi Braat, Catharina Beerendonk, Ronald Peek

J Assist Reprod Genet. 2021 Jun; 38(6): 1571–1588. Published online 2021 Mar 16. doi: 10.1007/s10815-021-02081-9

PMCID:: PMC8266964

Abstract Article PDF–29M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81470417.

Co-relation with novel phosphorylation sites of IκBα and necroptosis in breast cancer cells

Sung Hoon Choi, Hee-Sub Yoon, Shin-Ae Yoo, Sung Ho Yun, Joo-Hee Park, Eun Hee Han, Sung-Gil Chi, Young-Ho Chung

BMC Cancer. 2021; 21: 596. Published online 2021 May 24. doi: 10.1186/s12885-021-08304-7

Correction in:: BMC Cancer. 2021; 21: 1198.

PMCID:: PMC8147041

Abstract Article PDF–1.6M

Select item 77256018.

Aurora B and C kinases regulate chromosome desynapsis and segregation during mouse and human spermatogenesis

Stephen R. Wellard, Karen Schindler, Philip W. Jordan

J Cell Sci. 2020 Dec 1; 133(23): jcs248831. Published online 2020 Dec 4. doi: 10.1242/jcs.248831

PMCID:: PMC7725601

Abstract Article

Select item 75668819.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 742732710.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 716998311.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 694204412.

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity

Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller

Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119

PMCID:: PMC6942044

Abstract Article PDF–10M

Select item 677813713.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 674470914.

Characterization and risk association of polymorphisms in Aurora kinases A, B and C with genetic susceptibility to gastric cancer development

Aner Mesic, Marija Rogar, Petra Hudler, Nurija Bilalovic, Izet Eminovic, Radovan Komel

BMC Cancer. 2019; 19: 919. Published online 2019 Sep 14. doi: 10.1186/s12885-019-6133-z

PMCID:: PMC6744709

Abstract Article PDF–948K

Select item 643909115.

Whole-exome sequencing identified a novel mutation of AURKC in a Chinese family with macrozoospermia

Juan Hua, Yang-yang Wan

J Assist Reprod Genet. 2019 Mar; 36(3): 529–534. Published online 2018 Dec 29. doi: 10.1007/s10815-018-1374-3

PMCID:: PMC6439091

Abstract Article PDF–752K

Select item 621963316.

ΔNp63α Suppresses TGFB2 Expression and RHOA Activity to Drive Cell Proliferation in Squamous Cell Carcinomas

Christopher G. Abraham, Michael P. Ludwig, Zdenek Andrysik, Ahwan Pandey, Molishree Joshi, Matthew D. Galbraith, Kelly D. Sullivan, Joaquin M. Espinosa

Cell Rep. Author manuscript; available in PMC 2018 Nov 6.

Published in final edited form as: Cell Rep. 2018 Sep 18; 24(12): 3224–3236. doi: 10.1016/j.celrep.2018.08.058

PMCID:: PMC6219633

Abstract Article PDF–1.1M

Select item 579602217.

Differential Selective Pressures Experienced by the Aurora Kinase Gene Family

Joni M. Seeling, Alexis A. Farmer, Adam Mansfield, Hyuk Cho, Madhusudan Choudhary

Int J Mol Sci. 2018 Jan; 19(1): 72. Published online 2017 Dec 28. doi: 10.3390/ijms19010072

PMCID:: PMC5796022

Abstract Article PDF–8.9M

Select item 558672518.

Gene Expression of Aurora Kinases in Prostate Cancer and Nodular Hyperplasia Tissues

Emmanuel Nna, Jonathan Madukwe, Ejike Egbujo, Chris Obiorah, Charles Okolie, Godwin Echejoh, Amina Yahaya, James Adisa, Ijeoma Uzoma

Med Princ Pract. 2013 Jan; 22(2): 138–143. Published online 2012 Oct 13. doi: 10.1159/000342679

PMCID:: PMC5586725

Abstract Article PDF–444K

Select item 553161119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 491724120.

Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex

Kaori Sasai, Hiroshi Katayama, David H. Hawke, Subrata Sen

PLoS One. 2016; 11(6): e0157305. Published online 2016 Jun 22. doi: 10.1371/journal.pone.0157305

PMCID:: PMC4917241

Abstract Article PDF–6.1M

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