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Select item 110293291.

Identification of novel MAGE-A6- and MAGE-A12-derived HLA-A24-restricted cytotoxic T lymphocyte epitopes using an in silico peptide-docking assay

Yasuto Akiyama, Masaru Komiyama, Yoji Nakamura, Akira Iizuka, Chie Oshita, Akiko Kume, Masahiro Nogami, Haruo Miyata, Tadashi Ashizawa, Shusuke Yoshikawa, Yoshio Kiyohara, Ken Yamaguchi

Cancer Immunol Immunother. 2012 Dec; 61(12): 2311–2319. Published online 2012 Jun 16. doi: 10.1007/s00262-012-1298-1

PMCID:: PMC11029329

Abstract Article PDF–656K

Select item 110285302.

Immunogenicity of dendritic cells pulsed with MAGE3, Survivin and B-cell maturation antigen mRNA for vaccination of multiple myeloma patients

Willemijn Hobo, Leonie Strobbe, Frans Maas, Hanny Fredrix, Annelies Greupink-Draaisma, Ben Esendam, Theo de Witte, Frank Preijers, Henriëtte Levenga, Bas van Rees, Reinier Raymakers, Nicolaas Schaap, Harry Dolstra

Cancer Immunol Immunother. 2013 Aug; 62(8): 1381–1392. Published online 2013 Jun 2. doi: 10.1007/s00262-013-1438-2

PMCID:: PMC11028530

Abstract Article PDF–335K

Select item 97922003.

MAGE-A3 regulates tumor stemness in gastric cancer through the PI3K/AKT pathway

Qi-Ying Yu, Zhi-Wen Wang, Meng-Ying Zhou, Shang-Fu Li, Xing-Hua Liao

Aging (Albany NY) 2022 Dec 15; 14(23): 9579–9598. Published online 2022 Nov 8. doi: 10.18632/aging.204373

PMCID:: PMC9792200

Abstract Article PDF–3.4M

Select item 87557134.

Co-expression of cancer-testis antigens of MAGE-A6 and MAGE-A11 is associated with tumor aggressiveness in patients with bladder cancer

Monireh Mohsenzadegan, Mahdieh Razmi, Somayeh Vafaei, Maryam Abolhasani, Zahra Madjd, Leili Saeednejad Zanjani, Laleh Sharifi

Sci Rep. 2022; 12: 599. Published online 2022 Jan 12. doi: 10.1038/s41598-021-04510-2

Correction in:: Sci Rep. 2022; 12: 2330.

PMCID:: PMC8755713

Abstract Article PDF–2.9M

Select item 82248605.

Transcriptomic characterization of cancer-testis antigens identifies MAGEA3 as a driver of tumor progression in hepatocellular carcinoma

Amanda J. Craig, Teresa Garcia-Lezana, Marina Ruiz de Galarreta, Carlos Villacorta-Martin, Edgar G. Kozlova, Sebastiao N. Martins-Filho, Johann von Felden, Mehmet Eren Ahsen, Erin Bresnahan, Gabriela Hernandez-Meza, Ismail Labgaa, Delia D’Avola, Myron Schwartz, Josep M. Llovet, Daniela Sia, Swan Thung, Bojan Losic, Amaia Lujambio, Augusto Villanueva

PLoS Genet. 2021 Jun; 17(6): e1009589. Published online 2021 Jun 24. doi: 10.1371/journal.pgen.1009589

PMCID:: PMC8224860

Abstract Article PDF–3.7M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79463527.

Re-examination of MAGE-A3 as a T-cell Therapeutic Target

Aaron D. Martin, Xueyin Wang, Mark L. Sandberg, Kathleen R. Negri, Ming L. Wu, Dora Toledo Warshaviak, Grant B. Gabrelow, Michele E. McElvain, Bella Lee, Mark E. Daris, Han Xu, Alexander Kamb

J Immunother. 2021 Apr; 44(3): 95–105. Published online 2020 Dec 4. doi: 10.1097/CJI.0000000000000348

PMCID:: PMC7946352

Abstract Article PDF–1.5M

Select item 78065088.

IGF2BP1 is the first positive marker for anaplastic thyroid carcinoma diagnosis

Jacob Haase, Danny Misiak, Marcus Bauer, Nikolaos Pazaitis, Juliane Braun, Rebecca Pötschke, Alexander Mensch, Jessica Lilian Bell, Henning Dralle, Udo Siebolts, Claudia Wickenhauser, Kerstin Lorenz, Stefan Hüttelmaier

Mod Pathol. 2021; 34(1): 32–41. Published online 2020 Jul 27. doi: 10.1038/s41379-020-0630-0

PMCID:: PMC7806508

Abstract Article PDF–2.0M

Select item 76828619.

MAGE-A3 is a prognostic biomarker for poor clinical outcome in cutaneous squamous cell carcinoma with perineural invasion via modulation of cell proliferation

Aaron Chen, Alexis L. Santana, Nicole Doudican, Nazanin Roudiani, Kristian Laursen, Jean-Philippe Therrien, James Lee, Diane Felsen, John A. Carucci

PLoS One. 2020; 15(11): e0241551. Published online 2020 Nov 23. doi: 10.1371/journal.pone.0241551

PMCID:: PMC7682861

Abstract Article PDF–1.8M

Select item 716998310.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 716495311.

Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression

Yiu Huen Tsang, Yumeng Wang, Kathleen Kong, Caitlin Grzeskowiak, Oksana Zagorodna, Turgut Dogruluk, Hengyu Lu, Nicole Villafane, Venkata Hemanjani Bhavana, Daniela Moreno, Sarah H Elsea, Han Liang, Gordon B Mills, Kenneth L Scott

eLife. 2020; 9: e48963. Published online 2020 Apr 9. doi: 10.7554/eLife.48963

PMCID:: PMC7164953

Abstract Article PDF–1.9M

Select item 685635812.

Lnc-THOR silencing inhibits human glioma cell survival by activating MAGEA6-AMPK signaling

Jun Xue, Shan Zhong, Bo-min Sun, Qing-Fang Sun, Liang-Yun Hu, Si-Jian Pan

Cell Death Dis. 2019 Nov; 10(11): 866. Published online 2019 Nov 14. doi: 10.1038/s41419-019-2093-0

PMCID:: PMC6856358

Abstract Article PDF–1.8M

Select item 674264613.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 660700714.

Regulation of MAGE‐A3/6 by the CRL4‐DCAF12 ubiquitin ligase and nutrient availability

Ramya Ravichandran, Kiran Kodali, Junmin Peng, Patrick Ryan Potts

EMBO Rep. 2019 Jul; 20(7): e47352. Published online 2019 May 24. doi: 10.15252/embr.201847352

PMCID:: PMC6607007

Abstract Article PDF–2.7M

Select item 642409815.

PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBPβ

Gunnar Dittmar, Daniel Perez Hernandez, Elisabeth Kowenz-Leutz, Marieluise Kirchner, Günther Kahlert, Radoslaw Wesolowski, Katharina Baum, Maria Knoblich, Maria Hofstätter, Arnaud Muller, Jana Wolf, Ulf Reimer, Achim Leutz

iScience. 2019 Mar 29; 13: 351–370. Published online 2019 Mar 1. doi: 10.1016/j.isci.2019.02.026

PMCID:: PMC6424098

Abstract Article PDF–11M

Select item 629942216.

Cancer/testis Antigen MAGEA3 Interacts with STAT1 and Remodels the Tumor Microenvironment

Ying Wang, Xiao Song, Yutian Zheng, Zeyu Liu, Yan Li, Xiaoping Qian, Xuewen Pang, Yu Zhang, Yanhui Yin

Int J Med Sci. 2018; 15(14): 1702–1712. Published online 2018 Nov 22. doi: 10.7150/ijms.27643

PMCID:: PMC6299422

Abstract Article PDF–1.6M

Select item 565239717.

Treatment of Patients With Metastatic Cancer Using a Major Histocompatibility Complex Class II–Restricted T-Cell Receptor Targeting the Cancer Germline Antigen MAGE-A3

Yong-Chen Lu, Linda L. Parker, Tangying Lu, Zhili Zheng, Mary Ann Toomey, Donald E. White, Xin Yao, Yong F. Li, Paul F. Robbins, Steven A. Feldman, Pierre van der Bruggen, Christopher A. Klebanoff, Stephanie L. Goff, Richard M. Sherry, Udai S. Kammula, James C. Yang, Steven A. Rosenberg

J Clin Oncol. 2017 Oct 10; 35(29): 3322–3329. Published online 2017 Aug 15. doi: 10.1200/JCO.2017.74.5463

PMCID:: PMC5652397

Abstract Article PDF–1.4M

Select item 562991318.

Degradation of AMPK by a Cancer-Specific Ubiquitin Ligase

Carlos T. Pineda, Saumya Ramanathan, Klementina Fon Tacer, Jenny L. Weon, Malia B. Potts, Yi-Hung Ou, Michael A. White, Patrick Ryan Potts

Cell. Author manuscript; available in PMC 2017 Oct 6.

Published in final edited form as: Cell. 2015 Feb 12; 160(4): 715–728. doi: 10.1016/j.cell.2015.01.034

PMCID:: PMC5629913

Abstract Article PDF–2.5M

Select item 552049819.

MAGE-TRIM28 complex promotes the Warburg effect and hepatocellular carcinoma progression by targeting FBP1 for degradation

X Jin, Y Pan, L Wang, L Zhang, R Ravichandran, P R Potts, J Jiang, H Wu, H Huang

Oncogenesis. 2017 Apr; 6(4): e312. Published online 2017 Apr 10. doi: 10.1038/oncsis.2017.21

PMCID:: PMC5520498

Abstract Article PDF–4.7M

Select item 544356920.

Functional interaction between co-expressed MAGE-A proteins

Julieta E. Laiseca, María F. Ladelfa, Javier Cotignola, Leticia Y. Peche, Franco A. Pascucci, Bryan A. Castaño, Mario D. Galigniana, Claudio Schneider, Martin Monte

PLoS One. 2017; 12(5): e0178370. Published online 2017 May 24. doi: 10.1371/journal.pone.0178370

PMCID:: PMC5443569

Abstract Article PDF–3.7M

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