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Select item 83529641.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 82360782.

Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs

Katherine M. Almasy, Jonathan P. Davies, Lars Plate

Mol Cell Proteomics. 2021; 20: 100120. Published online 2021 Jun 27. doi: 10.1016/j.mcpro.2021.100120

PMCID:: PMC8236078

Abstract Article PDF–4.6M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77581854.

NFAT5 promotes oral squamous cell carcinoma progression in a hyperosmotic environment

Shohei Yoshimoto, Hiromitsu Morita, Miho Matsuda, Yoshinori Katakura, Masato Hirata, Shuichi Hashimoto

Lab Invest. 2021; 101(1): 38–50. Published online 2020 Sep 8. doi: 10.1038/s41374-020-00486-1

PMCID:: PMC7758185

Abstract Article PDF–6.9M

Select item 73923345.

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells

Seung W. Ryu, Rose Stewart, D. Chase Pectol, Nicolette A. Ender, Oshadi Wimalarathne, Ji-Hoon Lee, Carlos P. Zanini, Antony Harvey, Jon M. Huibregtse, Peter Mueller, Tanya T. Paull

PLoS Biol. 2020 Jul; 18(7): e3000606. Published online 2020 Jul 20. doi: 10.1371/journal.pbio.3000606

PMCID:: PMC7392334

Abstract Article PDF–2.7M

Select item 60444266.

Clinical features of congenital myasthenic syndrome due to mutations in DPAGT1

Sarah Finlayson, Jacqueline Palace, Katsiaryna Belaya, Timothy J Walls, Fiona Norwood, Georgina Burke, Janice L Holton, Samuel I Pascual-Pascual, Judith Cossins, David Beeson

J Neurol Neurosurg Psychiatry. Author manuscript; available in PMC 2018 Jul 13.

Published in final edited form as: J Neurol Neurosurg Psychiatry. 2013 Oct; 84(10): 1119–1125. Published online 2013 Feb 27. doi: 10.1136/jnnp-2012-304716

PMCID:: PMC6044426

Abstract Article PDF–522K

Select item 60444257.

Identification of DPAGT1 as a new gene in which mutations cause a congenital myasthenic syndrome

Katsiaryna Belaya, Sarah Finlayson, Judith Cossins, Wei Wei Liu, Susan Maxwell, Jacqueline Palace, David Beeson

Ann N Y Acad Sci. Author manuscript; available in PMC 2018 Jul 13.

Published in final edited form as: Ann N Y Acad Sci. 2012 Dec; 1275: 29–35. doi: 10.1111/j.1749-6632.2012.06790.x

PMCID:: PMC6044425

Abstract Article PDF–751K

Select item 58400188.

GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation

Jiho Yoo, Ellene H. Mashalidis, Alvin C. Y. Kuk, Kazuki Yamamoto, Benjamin Kaeser, Satoshi Ichikawa, Seok-Yong Lee

Nat Struct Mol Biol. Author manuscript; available in PMC 2018 Aug 19.

Published in final edited form as: Nat Struct Mol Biol. 2018 Mar; 25(3): 217–224. Published online 2018 Feb 19. doi: 10.1038/s41594-018-0031-y

PMCID:: PMC5840018

Abstract Article PDF–1.7M

Select item 56306009.

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism

Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell

Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8

PMCID:: PMC5630600

Abstract Article PDF–2.3M

Select item 555356810.

A role for mitochondrial translation in promotion of viability in K-Ras mutant cells

Timothy D. Martin, Danielle R. Cook, Mei Yuk Choi, Mamie Z. Li, Kevin M. Haigis, Stephen J. Elledge

Cell Rep. Author manuscript; available in PMC 2017 Aug 11.

Published in final edited form as: Cell Rep. 2017 Jul 11; 20(2): 427–438. doi: 10.1016/j.celrep.2017.06.061

PMCID:: PMC5553568

Abstract Article PDF–1.8M

Select item 553161111.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 549101012.

DPAGT1-CDG: Functional analysis of disease-causing pathogenic mutations and role of endoplasmic reticulum stress

Patricia Yuste-Checa, Ana I. Vega, Cristina Martín-Higueras, Celia Medrano, Alejandra Gámez, Lourdes R. Desviat, Magdalena Ugarte, Celia Pérez-Cerdá, Belén Pérez

PLoS One. 2017; 12(6): e0179456. Published online 2017 Jun 29. doi: 10.1371/journal.pone.0179456

PMCID:: PMC5491010

Abstract Article PDF–11M

Select item 464794113.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 460382714.

N-Acetylglucosaminyl 1-Phosphate Transferase: An Excellent Target for Developing New Generation Breast Cancer Therapeutic

Aditi Banerjee, Juan A. Martinez, Maria O. Longas, Zhenbo Zhang, Jesus Santiago, Krishna Baksi, Dipak K. Banerjee

Adv Exp Med Biol. Author manuscript; available in PMC 2015 Oct 13.

Published in final edited form as: Adv Exp Med Biol. 2015; 842: 355–374. doi: 10.1007/978-3-319-11280-0_22

PMCID:: PMC4603827

Abstract Article PDF–817K

Select item 374615415.

Clinical features in a large Iranian family with a limb-girdle congenital myasthenic syndrome due to a mutation in DPAGT1

Keivan Basiri, Katsiaryna Belaya, Wei Wei Liu, Susan Maxwell, Maryam Sedghi, David Beeson

Neuromuscul Disord. 2013 Jun; 23(6): 469–472. doi: 10.1016/j.nmd.2013.03.003

PMCID:: PMC3746154

Abstract Article PDF–487K

Select item 372267316.

A compound heterozygous mutation in DPAGT1 results in a congenital disorder of glycosylation with a relatively mild phenotype

Zafar Iqbal, Mohsin Shahzad, Lisenka E L M Vissers, Monique van Scherpenzeel, Christian Gilissen, Attia Razzaq, Muhammad Yasir Zahoor, Shaheen N Khan, Tjitske Kleefstra, Joris A Veltman, Arjan P M de Brouwer, Dirk J Lefeber, Hans van Bokhoven, Sheikh Riazuddin

Eur J Hum Genet. 2013 Aug; 21(8): 844–849. Published online 2012 Dec 19. doi: 10.1038/ejhg.2012.257

PMCID:: PMC3722673

Abstract Article PDF–1.5M

Select item 371128917.

N-Glycosylation Induces the CTHRC1 Protein and Drives Oral Cancer Cell Migration

Gangli Liu, Pritam K. Sengupta, Basem Jamal, Hsiao-Ying Yang, Meghan P. Bouchie, Volkhard Lindner, Xaralabos Varelas, Maria A. Kukuruzinska

J Biol Chem. 2013 Jul 12; 288(28): 20217–20227. Published online 2013 May 23. doi: 10.1074/jbc.M113.473785

PMCID:: PMC3711289

Abstract Article PDF–4.1M

Select item 361318018.

Coordinate regulation of N-glycosylation gene DPAGT1, canonical Wnt signaling and E-cadherin adhesion

Pritam K. Sengupta, Meghan P. Bouchie, Mihai Nita-Lazar, Hsiao-Ying Yang, Maria A. Kukuruzinska

J Cell Sci. 2013 Jan 15; 126(2): 484–496. doi: 10.1242/jcs.113035

PMCID:: PMC3613180

Abstract Article

Select item 339725919.

Mutations in DPAGT1 Cause a Limb-Girdle Congenital Myasthenic Syndrome with Tubular Aggregates

Katsiaryna Belaya, Sarah Finlayson, Clarke R. Slater, Judith Cossins, Wei Wei Liu, Susan Maxwell, Simon J. McGowan, Siarhei Maslau, Stephen R.F. Twigg, Timothy J. Walls, Samuel I. Pascual Pascual, Jacqueline Palace, David Beeson

Am J Hum Genet. 2012 Jul 13; 91(1): 193–201. doi: 10.1016/j.ajhg.2012.05.022

PMCID:: PMC3397259

Abstract Article PDF–1.0M

Select item 336268320.

Aberrant Amplification of the Crosstalk between Canonical Wnt Signaling and N-glycosylation Gene DPAGT1 Promotes Oral Cancer

Basem Jamal, Pritam K. Sengupta, Zhen-nan Gao, Mihai Nita-Lazar, Bakr Amin, Sharuch Jalisi, Meghan P. Bouchie, Maria A. Kukuruzinska

Oral Oncol. Author manuscript; available in PMC 2013 Jun 1.

Published in final edited form as: Oral Oncol. 2012 Jun; 48(6): 523–529. Published online 2012 Feb 15. doi: 10.1016/j.oraloncology.2012.01.010

PMCID:: PMC3362683

Abstract Article PDF–1.1M

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