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Select item 109621181.

PELI1: key players in the oncogenic characteristics of pancreatic Cancer

Xiaobin Fei, Changhao Zhu, Peng Liu, Songbai Liu, Likun Ren, Rishang Lu, Junyi Hou, Yongjia Gao, Xing Wang, Yaozhen Pan

J Exp Clin Cancer Res. 2024; 43: 91. Published online 2024 Mar 25. doi: 10.1186/s13046-024-03008-9

PMCID:: PMC10962118

Abstract Article PDF–15M

Select item 99683142.

PELI1 and EGFR cooperate to promote breast cancer metastasis

Jie Qi, Guangsen Xu, Xiaoxia Wu, Chunhua Lu, Yuemao Shen, Baobing Zhao

Oncogenesis. 2023 Dec; 12(1): 9. Published online 2023 Feb 25. doi: 10.1038/s41389-023-00457-3

PMCID:: PMC9968314

Abstract Article PDF–5.2M

Select item 89365153.

PELI1 promotes radiotherapy sensitivity by inhibiting noncanonical NF‐κB in esophageal squamous cancer

Dongfang Dai, Hongping Zhou, Li Yin, Fei Ye, Xiao Yuan, Tao You, Xiaohui Zhao, Weiguo Long, Deqiang Wang, Xia He, Jifeng Feng, Deyu Chen

Mol Oncol. 2022 Mar; 16(6): 1384–1401. Published online 2021 Nov 14. doi: 10.1002/1878-0261.13134

PMCID:: PMC8936515

Abstract Article PDF–3.9M

Select item 89245954.

miR-590-5p Overexpression Alleviates β-Amyloid-Induced Neuron Damage via Targeting Pellino-1

Lin Shang, Tao Peng, Xuemei Chen, Zhiyong Yan, Junmin Wang, Xiaoqun Gao, Cheng Chang

Anal Cell Pathol (Amst) 2022; 2022: 7657995. Published online 2022 Mar 8. doi: 10.1155/2022/7657995

PMCID:: PMC8924595

Abstract Article PDF–3.5M

Select item 87404685.

MiR-30c-5p loss-induced PELI1 accumulation regulates cell proliferation and migration via activating PI3K/AKT pathway in papillary thyroid carcinoma

Tingting Zheng, Youxing Zhou, Xiaowei Xu, Xin Qi, Jiameng Liu, Yanan Pu, Shan Zhang, Xuerong Gao, Xinkai Luo, Mei Li, Xuefeng Wang, Liyang Dong, Ying Wang, Chaoming Mao

J Transl Med. 2022; 20: 20. Published online 2022 Jan 6. doi: 10.1186/s12967-021-03226-1

PMCID:: PMC8740468

Abstract Article PDF–7.5M

Select item 86845206.

MiR-301a-3p Advances IRAK1-Mediated Differentiation of Th17 Cells to Promote the Progression of Systemic Lupus Erythematosus via Targeting PELI1

Shuaihantian Luo, Ruifang Wu, Qianwen Li, Guiying Zhang

J Healthc Eng. 2021; 2021: 2982924. Published online 2021 Dec 11. doi: 10.1155/2021/2982924

PMCID:: PMC8684520

Abstract Article PDF–550K

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78097028.

The E3 ubiquitin ligase Peli1 regulates the metabolic actions of mTORC1 to suppress antitumor T cell responses

Chun‐Jung Ko, Lingyun Zhang, Zuliang Jie, Lele Zhu, Xiaofei Zhou, Xiaoping Xie, Tianxiao Gao, Jin‐Young Yang, Xuhong Cheng, Shao‐Cong Sun

EMBO J. 2021 Jan 15; 40(2): e104532. Published online 2020 Nov 20. doi: 10.15252/embj.2020104532

PMCID:: PMC7809702

Abstract Article PDF–1.9M

Select item 75460079.

Redox DAPK1 destabilizes Pellino1 to govern inflammation-coupling tubular damage during septic AKI

Bang-Chuan Hu, Guo-Hua Wu, Zi-Qiang Shao, Yang Zheng, Jin-Quan Liu, Run Zhang, Jun Hong, Xiang-Hong Yang, Ren-Hua Sun, Shi-Jing Mo

Theranostics. 2020; 10(25): 11479–11496. Published online 2020 Sep 15. doi: 10.7150/thno.49870

PMCID:: PMC7546007

Abstract Article PDF–3.4M

Select item 739176510.

Resistomycin attenuates triple-negative breast cancer progression by inhibiting E3 ligase Pellino-1 and inducing SNAIL/SLUG degradation

Shan-shan Liu, Jie Qi, Zu-dong Teng, Fu-tao Tian, Xiao-xi Lv, Ke Li, Ya-jie Song, Wei-dong Xie, Zhuo-wei Hu, Xia Li

Signal Transduct Target Ther. 2020; 5: 133. Published online 2020 Jul 29. doi: 10.1038/s41392-020-00255-y

PMCID:: PMC7391765

Article PDF–1.2M

Select item 729731011.

Peli1 signaling blockade attenuates congenital zika syndrome

Huanle Luo, Guangyu Li, Binbin Wang, Bing Tian, Junling Gao, Jing Zou, Shuizhen Shi, Shuang Zhu, Bi-Hung Peng, Awadalkareem Adam, Ariza Martinez, Kimberly Hein, Evandro R. Winkelmann, Yoseph Mahmoud, Xiaofei Zhou, Chao Shan, Shannan Rossi, Scott Weaver, Alan D. T. Barrett, Shao-Cong Sun, Wenbo Zhang, Pei-Yong Shi, Ping Wu, Tian Wang

PLoS Pathog. 2020 Jun; 16(6): e1008538. Published online 2020 Jun 16. doi: 10.1371/journal.ppat.1008538

PMCID:: PMC7297310

Abstract Article PDF–2.8M

Select item 717492912.

miR-21 and Pellino-1 Expression Profiling in Autoimmune Premature Ovarian Insufficiency

Xinran Li, Jiaxin Xie, Qingru Wang, Huihua Cai, Chuhai Xie, Xiafei Fu

J Immunol Res. 2020; 2020: 3582648. Published online 2020 Apr 13. doi: 10.1155/2020/3582648

PMCID:: PMC7174929

Abstract Article PDF–1.1M

Select item 716998313.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 675307614.

HPD degradation regulated by the TTC36-STK33-PELI1 signaling axis induces tyrosinemia and neurological damage

Yajun Xie, Xiaoyan Lv, Dongsheng Ni, Jianing Liu, Yanxia Hu, Yamin Liu, Yunhong Liu, Rui Liu, Hui Zhao, Zhimin Lu, Qin Zhou

Nat Commun. 2019; 10: 4266. Published online 2019 Sep 19. doi: 10.1038/s41467-019-12011-0

PMCID:: PMC6753076

Abstract Article PDF–2.4M

Select item 654165215.

Peli1 controls the survival of dopaminergic neurons through modulating microglia-mediated neuroinflammation

Dongfang Dai, Jia Yuan, Yan Wang, Jing Xu, Chaoming Mao, Yichuan Xiao

Sci Rep. 2019; 9: 8034. Published online 2019 May 29. doi: 10.1038/s41598-019-44573-w

PMCID:: PMC6541652

Abstract Article PDF–3.3M

Select item 645097216.

Pellino1 regulates reversible ATM activation via NBS1 ubiquitination at DNA double-strand breaks

Geun-Hyoung Ha, Jae-Hoon Ji, Sunyoung Chae, Jihyun Park, Suhyeon Kim, Jin-Kwan Lee, Yonghyeon Kim, Sunwoo Min, Jeong-Min Park, Tae-Hong Kang, Ho Lee, Hyeseong Cho, Chang-Woo Lee

Nat Commun. 2019; 10: 1577. Published online 2019 Apr 5. doi: 10.1038/s41467-019-09641-9

PMCID:: PMC6450972

Abstract Article PDF–5.5M

Select item 629825417.

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert

Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289

PMCID:: PMC6298254

Abstract Article PDF–1.4M

Select item 598469118.

Peli1 modulates the subcellular localization and activity of Mdmx

Dawei Li, Omid Tavana, Shao-Cong Sun, Wei Gu

Cancer Res. Author manuscript; available in PMC 2019 Jun 1.

Published in final edited form as: Cancer Res. 2018 Jun 1; 78(11): 2897–2910. Published online 2018 Mar 9. doi: 10.1158/0008-5472.CAN-17-3531

PMCID:: PMC5984691

Abstract Article PDF–1.2M

Select item 593086419.

Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation

Sinéad Kinsella, Michael Fichtner, Orla Watters, Hans-Georg König, Jochen H. M. Prehn

J Neuroinflammation. 2018; 15: 130. Published online 2018 May 2. doi: 10.1186/s12974-018-1143-3

PMCID:: PMC5930864

Abstract Article PDF–2.0M

Select item 585915020.

Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus

Junli Liu, Xinfang Huang, Shumeng Hao, Yan Wang, Manman Liu, Jing Xu, Xingli Zhang, Tao Yu, Shucheng Gan, Dongfang Dai, Xuan Luo, Qingyan Lu, Chaoming Mao, Yanyun Zhang, Nan Shen, Bin Li, Mingzhu Huang, Xiaodong Zhu, Jin Jin, Xuhong Cheng, Shao-Cong Sun, Yichuan Xiao

Nat Commun. 2018; 9: 1136. Published online 2018 Mar 19. doi: 10.1038/s41467-018-03530-3

PMCID:: PMC5859150

Abstract Article PDF–2.8M

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