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Items: 1 to 20 of 35

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Dynamic encounters with red blood cells trigger splenic marginal zone B cell retention and function
Dan Liu, Benjamin Y. Winer, Marissa Y. Chou, Hanson Tam, Ying Xu, Jinping An, James M. Gardner, Jason G. Cyster
Nat Immunol. 2024; 25(1): 142–154. Published online 2023 Dec 4. doi: 10.1038/s41590-023-01690-z
PMCID:
PMC10761324
AbstractArticlePDF–11M
3.
CD97 promotes spleen dendritic cell homeostasis through the mechanosensing of red blood cells
Dan Liu, Lihui Duan, Lauren B Rodda, Erick Lu, Ying Xu, Jinping An, Longhui Qiu, Fengchun Liu, Mark R Looney, Zhiyong Yang, Christopher D C Allen, Zhongmei Li, Alexander Marson, Jason G Cyster
Science. Author manuscript; available in PMC 2023 Feb 11.
Published in final edited form as: Science. 2022 Feb 11; 375(6581): eabi5965. Published online 2022 Feb 11. doi: 10.1126/science.abi5965
PMCID:
PMC9310086
AbstractArticlePDF–2.9M
4.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
5.
A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation
Louise van der Weyden, Agnieszka Swiatkowska, Vivek Iyer, Anneliese O. Speak, David J. Adams
G3 (Bethesda) 2020 Jun; 10(6): 1869–1877. Published online 2020 Apr 3. doi: 10.1534/g3.120.401128
PMCID:
PMC7263671
AbstractArticlePDF–1.0M
6.
Arhgef1 Plays a Vital Role in Platelet Function and Thrombogenesis
Hanan Qasim, Zubair A. Karim, Keziah R. Hernandez, Dante Lozano, Fadi T. Khasawneh, Fatima Z. Alshbool
J Am Heart Assoc. 2019 May 7; 8(9): e011712. Published online 2019 Apr 17. doi: 10.1161/JAHA.118.011712
PMCID:
PMC6512111
AbstractArticlePDF–2.1M
7.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
8.
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells
Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch
Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262
PMCID:
PMC6244183
AbstractArticlePDF–753K
9.
Leukocyte RhoA exchange factor Arhgef1 mediates vascular inflammation and atherosclerosis
Maria Luigia Carbone, Gilliane Chadeuf, Sandrine Heurtebise-Chrétien, Xavier Prieur, Thibault Quillard, Yann Goueffic, Nathalie Vaillant, Marc Rio, Laure Castan, Maxim Durand, Céline Baron-Menguy, Julien Aureille, Juliette Desfrançois, Angela Tesse, Raul M. Torres, Gervaise Loirand
J Clin Invest. 2017 Dec 1; 127(12): 4516–4526. Published online 2017 Nov 13. doi: 10.1172/JCI92702
PMCID:
PMC5707138
AbstractArticlePDF–6.7M
10.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
11.
Loss of signaling via Ga13 in germinal center B cell-derived lymphoma
Jagan R. Muppidi, Roland Schmitz, Jesse A. Green, Wenming Xiao, Adrien B. Larsen, Sterling E. Braun, Jinping An, Ying Xu, Andreas Rosenwald, German Ott, Randy D. Gascoyne, Lisa M. Rimsza, Elias Campo, Elaine S. Jaffe, Jan Delabie, Erlend B. Smeland, Rita M. Braziel, Raymond R. Tubbs, J. R. Cook, Dennis D. Weisenburger, Wing C. Chan, Nagarajan Vaidehi, Louis M. Staudt, Jason G. Cyster
Nature. Author manuscript; available in PMC 2015 Jun 11.
Published in final edited form as: Nature. 2014 Dec 11; 516(7530): 254–258. Published online 2014 Sep 28. doi: 10.1038/nature13765
PMCID:
PMC4267955
AbstractArticlePDF–1.9M
12.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
13.
Transcription factor Foxp3 and its protein partners form a complex regulatory network
Dipayan Rudra, Paul deRoos, Ashutosh Chaudhry, Rachel Niec, Aaron Arvey, Robert M. Samstein, Christina Leslie, Scott A. Shaffer, David R. Goodlett, Alexander Y. Rudensky
Nat Immunol. Author manuscript; available in PMC 2013 Apr 1.
Published in final edited form as: Nat Immunol. 2012 Oct; 13(10): 1010–1019. Published online 2012 Aug 26. doi: 10.1038/ni.2402
PMCID:
PMC3448012
AbstractArticlePDF–2.6M
14.
Acute Activation of β2-Adrenergic Receptor Regulates Focal Adhesions through βArrestin2- and p115RhoGEF Protein-mediated Activation of RhoA
Xiaojie Ma, Yu Zhao, Yehia Daaka, Zhongzhen Nie
J Biol Chem. 2012 Jun 1; 287(23): 18925–18936. Published online 2012 Apr 12. doi: 10.1074/jbc.M112.352260
PMCID:
PMC3365927
AbstractArticlePDF–4.2M
15.
Thromboxane Receptor Signaling Is Required for Fibronectin-induced Matrix Metalloproteinase 9 Production by Human and Murine Macrophages and Is Attenuated by the Arhgef1 Molecule
John M. Hartney, Claire E. Gustafson, Russell P. Bowler, Roberta Pelanda, Raul M. Torres
J Biol Chem. 2011 Dec 30; 286(52): 44521–44531. Published online 2011 Nov 15. doi: 10.1074/jbc.M111.282772
PMCID:
PMC3247948
AbstractArticlePDF–962K
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
The sphingosine 1-phosphate receptor S1P2 maintains germinal center B cell homeostasis and promotes niche confinement
Jesse A. Green, Kazuhiro Suzuki, Bryan Cho, L. David Willison, Daniel Palmer, Christopher D.C. Allen, Timothy H. Schmidt, Ying Xu, Richard L. Proia, Shaun R. Coughlin, Jason G. Cyster
Nat Immunol. Author manuscript; available in PMC 2012 Jan 1.
Published in final edited form as: Nat Immunol. 2011 Jul; 12(7): 672–680. Published online 2011 Jun 5. doi: 10.1038/ni.2047
PMCID:
PMC3158008
AbstractArticlePDF–3.7M
18.
Protein kinase C-α signals P115RhoGEF phosphorylation and RhoA activation in TNF-α-induced mouse brain microvascular endothelial cell barrier dysfunction
Jing Peng, Fang He, Ciliu Zhang, Xiaolu Deng, Fei Yin
J Neuroinflammation. 2011; 8: 28. Published online 2011 Apr 8. doi: 10.1186/1742-2094-8-28
PMCID:
PMC3080812
AbstractArticlePDF–776K
19.
Arhgef1 Regulates α5β1 Integrin-Mediated Matrix Metalloproteinase Expression and Is Required for Homeostatic Lung Immunity
John M. Hartney, Jeanette Brown, Hong Wei Chu, Ling Yi Chang, Roberta Pelanda, Raul M. Torres
Am J Pathol. 2010 Mar; 176(3): 1157–1168. doi: 10.2353/ajpath.2010.090200
PMCID:
PMC2832139
AbstractArticlePDF–518K
20.
Recognition of the activated states of Gα13 by the rgRGS domain of PDZRhoGEF
Zhe Chen, William D. Singer, Shahab M. Danesh, Paul C. Sternweis, Stephen R. Sprang
Structure. Author manuscript; available in PMC 2009 Oct 8.
Published in final edited form as: Structure. 2008 Oct 8; 16(10): 1532–1543. doi: 10.1016/j.str.2008.07.009
PMCID:
PMC2586972
AbstractArticlePDF–3.7M

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