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Select item 103232521.

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families

Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick T. Caswell

J Cell Sci. 2023 Jun 15; 136(12): jcs260468. Published online 2023 Jun 23. doi: 10.1242/jcs.260468

PMCID:: PMC10323252

Abstract Article

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 92792853.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 91197364.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 88970225.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 83641816.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76571798.

Genome‐wide association study of chemotherapeutic agent‐induced severe neutropenia/leucopenia for patients in Biobank Japan

Siew‐Kee Low, Suyoun Chung, Atsushi Takahashi, Hitoshi Zembutsu, Taisei Mushiroda, Michiaki Kubo, Yusuke Nakamura

Cancer Sci. 2013 Aug; 104(8): 1074–1082. Published online 2013 Jun 10. doi: 10.1111/cas.12186

PMCID:: PMC7657179

Abstract Article PDF–225K

Select item 75940879.

A Screen for PKN3 Substrates Reveals an Activating Phosphorylation of ARHGAP18

Michal Dibus, Jan Brábek, Daniel Rösel

Int J Mol Sci. 2020 Oct; 21(20): 7769. Published online 2020 Oct 20. doi: 10.3390/ijms21207769

PMCID:: PMC7594087

Abstract Article PDF–2.3M

Select item 752370610.

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis

Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D. Malihi, Mincheol Park, Ruth M. Alvarez, Li Peng Yap, Parag Mallick, Jonathan E. Katz, Mitchell E. Gross, Kian Kani

Oncogene. Author manuscript; available in PMC 2020 Sep 29.

Published in final edited form as: Oncogene. 2019 Apr; 38(16): 3003–3018. Published online 2018 Dec 21. doi: 10.1038/s41388-018-0638-9

PMCID:: PMC7523706

Abstract Article PDF–2.3M

Select item 711512811.

Targeting RICTOR sensitizes SMAD4-negative colon cancer to irinotecan

Chen Khuan Wong, Arthur William Lambert, Sait Ozturk, Panagiotis Papageorgis, Delia Lopez, Ning Shen, Zaina Sen, Hamid Mostafavi Abdolmaleky, Balázs Győrffy, Hui Feng, Sam Thiagalingam

Mol Cancer Res. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Mol Cancer Res. 2020 Mar; 18(3): 414–423. Published online 2020 Jan 13. doi: 10.1158/1541-7786.MCR-19-0525

PMCID:: PMC7115128

Abstract Article PDF–1.6M

Select item 699814412.

YAP and the RhoC regulator ARHGAP18, are required to mediate flow-dependent endothelial cell alignment

Paul R. Coleman, Angelina J. Lay, Ka Ka Ting, Yang Zhao, Jia Li, Sorour Jarrah, Mathew A. Vadas, Jennifer R. Gamble

Cell Commun Signal. 2020; 18: 18. Published online 2020 Feb 3. doi: 10.1186/s12964-020-0511-7

PMCID:: PMC6998144

Abstract Article PDF–7.2M

Select item 644186813.

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1

Boshi Wang, Xiaoli Xu, Zhaojuan Yang, Li Zhang, Yun Liu, Aihui Ma, Guiqin Xu, Ming Tang, Tiantian Jing, Lin Wu, Yongzhong Liu

EBioMedicine. 2019 Mar; 41: 320–332. Published online 2019 Feb 7. doi: 10.1016/j.ebiom.2019.01.058

PMCID:: PMC6441868

Abstract Article PDF–7.0M

Select item 628684314.

LncRNA CDKN2BAS predicts poor prognosis in patients with hepatocellular carcinoma and promotes metastasis via the miR-153-5p/ARHGAP18 signaling axis

Junzheng Chen, Xitian Huang, Weijun Wang, Hongcheng Xie, Jianfeng Li, Zhenfen Hu, Zhijian Zheng, Huiyong Li, Lingfang Teng

Aging (Albany NY) 2018 Nov; 10(11): 3371–3381. Published online 2018 Nov 29. doi: 10.18632/aging.101645

PMCID:: PMC6286843

Abstract Article PDF–3.1M

Select item 539118315.

The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells

Michael D. Lovelace, Elizabeth E. Powter, Paul R. Coleman, Yang Zhao, Amelia Parker, Garry H. Chang, Angelina J. Lay, Julie Hunter, Aaron P. McGrath, Mika Jormakka, Patrick Bertolino, Geoffrey McCaughan, Maria Kavallaris, Mathew A. Vadas, Jennifer R. Gamble

Mol Biol Cell. 2017 Apr 15; 28(8): 1066–1078. doi: 10.1091/mbc.E16-05-0285

PMCID:: PMC5391183

Abstract Article PDF–3.0M

Select item 538342316.

Association of ARHGAP18 polymorphisms with schizophrenia in the Chinese-Han population

Weiyun Guo, Yaqi Cai, Hongxing Zhang, Yongfeng Yang, Ge Yang, Xiujuan Wang, Jingyuan Zhao, Juntang Lin, Jinfu Zhu, Wenqiang Li, Luxian Lv

PLoS One. 2017; 12(4): e0175209. Published online 2017 Apr 6. doi: 10.1371/journal.pone.0175209

PMCID:: PMC5383423

Abstract Article PDF–1.4M

Select item 497239717.

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

Zhenhuan Guo, Lisa J Neilson, Hang Zhong, Paul S Murray, Megha Vaman Rao, Sara Zanivan, Ronen Zaidel-Bar

Sci Signal. Author manuscript; available in PMC 2016 Aug 3.

Published in final edited form as: Sci Signal. 2014 Dec 2; 7(354): rs7. Published online 2014 Dec 2. doi: 10.1126/scisignal.2005473

PMCID:: PMC4972397

Abstract Article PDF–3.1M

Select item 460118718.

ARHGAP18: an endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctions

Garry HK Chang, Angelina J Lay, Ka Ka Ting, Yang Zhao, Paul R Coleman, Elizabeth E Powter, Ann Formaz-Preston, Christopher J Jolly, Neil I Bower, Benjamin M Hogan, Silke Rinkwitz, Thomas S Becker, Mathew A Vadas, Jennifer R Gamble

Small GTPases. 2014; 5(3): e975002. Published online 2014 Nov 25. doi: 10.4161/21541248.2014.975002

PMCID:: PMC4601187

Abstract Article PDF–1.9M

Select item 441803019.

Heritability and genetic association analysis of cognition in the Diabetes Heart Study

Amanda J. Cox, Christina E. Hugenschmidt, Laura M. Raffield, Carl D. Langefeld, Barry I. Freedman, Jeff D. Williamson, Fang-Chi Hsu, Donald W. Bowden

Neurobiol Aging. Author manuscript; available in PMC 2015 May 4.

Published in final edited form as: Neurobiol Aging. 2014 Aug; 35(8): 1958.e3–1958.e12. Published online 2014 Mar 11. doi: 10.1016/j.neurobiolaging.2014.03.005

PMCID:: PMC4418030

Abstract Article PDF–1.5M

Select item 393156420.

Genome-Wide Association Study of Periodontal Health Measured by Probing Depth in Adults Ages 18−49 years

John R. Shaffer, Deborah E. Polk, Xiaojing Wang, Eleanor Feingold, Daniel E. Weeks, Myoung-Keun Lee, Karen T. Cuenco, Robert J. Weyant, Richard J. Crout, Daniel W. McNeil, Mary L. Marazita

G3 (Bethesda) 2014 Feb; 4(2): 307–314. Published online 2013 Dec 17. doi: 10.1534/g3.113.008755

PMCID:: PMC3931564

Abstract Article PDF–1.2M

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