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Select item 110703901.

A study of the association between single nucleotide polymorphisms of the endoplasmic reticulum aminopeptidase 2 (ERAP2) gene and the risk of ankylosing spondylitis in Egyptians

Randa Mohamed Ibrahim Mesahel, Dina Salem Fotoh, Mahmoud Mohammed Hadhoud, Mohamed Farag Ali Assar

Mol Biol Rep. 2024; 51(1): 614. Published online 2024 May 5. doi: 10.1007/s11033-024-09404-w

PMCID:: PMC11070390

Abstract Article PDF–1.4M

Select item 110305532.

Distinct molecular mechanisms leading to deficient expression of ER-resident aminopeptidases in melanoma

Esther Kamphausen, Christiane Kellert, Tarish Abbas, Nadja Akkad, Stefan Tenzer, Graham Pawelec, Hansjoerg Schild, Peter van Endert, Barbara Seliger

Cancer Immunol Immunother. 2010 Aug; 59(8): 1273–1284. Published online 2010 Apr 24. doi: 10.1007/s00262-010-0856-7

PMCID:: PMC11030553

Abstract Article PDF–527K

Select item 107947813.

A cis-regulatory element regulates ERAP2 expression through autoimmune disease risk SNPs

Wouter J. Venema, Sanne Hiddingh, Jorg van Loosdregt, John Bowes, Brunilda Balliu, Joke H. de Boer, Jeannette Ossewaarde-van Norel, Susan D. Thompson, Carl D. Langefeld, Aafke de Ligt, Lars T. van der Veken, Peter H.L. Krijger, Wouter de Laat, Jonas J.W. Kuiper

Cell Genom. 2024 Jan 10; 4(1): 100460. Published online 2023 Dec 5. doi: 10.1016/j.xgen.2023.100460

PMCID:: PMC10794781

Abstract Article PDF–4.2M

Select item 104881874.

ERAP1 and ERAP2 Haplotypes Influence Suboptimal HLA-B*27:05-Restricted Anti-Viral CD8+ T Cell Responses Cross-Reactive to Self-Epitopes

Valentina Tedeschi, Giorgia Paldino, Josephine Alba, Emanuele Molteni, Fabiana Paladini, Rossana Scrivo, Mattia Congia, Alberto Cauli, Rosalba Caccavale, Marino Paroli, Manuela Di Franco, Loretta Tuosto, Rosa Sorrentino, Marco D’Abramo, Maria Teresa Fiorillo

Int J Mol Sci. 2023 Sep; 24(17): 13335. Published online 2023 Aug 28. doi: 10.3390/ijms241713335

PMCID:: PMC10488187

Abstract Article PDF–3.0M

Select item 99654925.

A Comparative Review of Pregnancy and Cancer and Their Association with Endoplasmic Reticulum Aminopeptidase 1 and 2

Brian Hur, Veronica Wong, Eun D. Lee

Int J Mol Sci. 2023 Feb; 24(4): 3454. Published online 2023 Feb 9. doi: 10.3390/ijms24043454

PMCID:: PMC9965492

Abstract Article PDF–323K

Select item 97744886.

The ER Aminopeptidases, ERAP1 and ERAP2, synergize to self-modulate their respective activities

Adrian Martín-Esteban, Jesus Contreras Rodriguez, David Peske, Jose A. Lopez de Castro, Nilabh Shastri, Scheherazade Sadegh-Nasseri

Front Immunol. 2022; 13: 1066483. Published online 2022 Dec 8. doi: 10.3389/fimmu.2022.1066483

PMCID:: PMC9774488

Abstract Article PDF–1.7M

Select item 95962067.

ERAP2 as a potential biomarker for predicting gemcitabine response in patients with pancreatic cancer

Pian Yu, Shifu Luo, Jiaxin Cai, Jie Li, Cong Peng

Aging (Albany NY) 2022 Oct 15; 14(19): 7941–7958. Published online 2022 Oct 8. doi: 10.18632/aging.204324

PMCID:: PMC9596206

Abstract Article PDF–1.5M

Select item 87259958.

ERAP2 Is Associated With Immune Infiltration and Predicts Favorable Prognosis in SqCLC

Zhenlin Yang, He Tian, Fenglong Bie, Jiachen Xu, Zheng Zhou, Junhui Yang, Renda Li, Yue Peng, Guangyu Bai, Yanhua Tian, Ying Chen, Lei Liu, Tao Fan, Chu Xiao, Yujia Zheng, Bo Zheng, Jie Wang, Chunxiang Li, Shugeng Gao, Jie He

Front Immunol. 2021; 12: 788985. Published online 2021 Dec 21. doi: 10.3389/fimmu.2021.788985

PMCID:: PMC8725995

Abstract Article PDF–23M

Select item 85725109.

ERAP1, ERAP2, and Two Copies of HLA-Aw19 Alleles Increase the Risk for Birdshot Chorioretinopathy in HLA-A29 Carriers

Sahar Gelfman, Dominique Monnet, Ann J. Ligocki, Thierry Tabary, Arden Moscati, Xiaodong Bai, Jan Freudenberg, Blerta Cooper, Jack A. Kosmicki, Sarah Wolf, Manuel A. R. Ferreira, John Overton, Jonathan Weyne, Eli A. Stahl, Aris Baras, Carmelo Romano, Jacques H. M. Cohen, Giovanni Coppola, Antoine Brézin, for the Regeneron Genetics Center

Invest Ophthalmol Vis Sci. 2021 Nov; 62(14): 3. Published online 2021 Nov 2. doi: 10.1167/iovs.62.14.3

PMCID:: PMC8572510

Abstract Article PDF–1.1M

Select item 839533610.

Overexpression of ERAP2N in Human Trophoblast Cells Promotes Cell Death

Kristen Lospinoso, Mikhail Dozmorov, Nadine El Fawal, Rhea Raghu, Wook-Jin Chae, Eun D. Lee

Int J Mol Sci. 2021 Aug; 22(16): 8585. Published online 2021 Aug 10. doi: 10.3390/ijms22168585

PMCID:: PMC8395336

Abstract Article PDF–2.4M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 799095612.

Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women

Leonardo Capistrano Ferreira, Carlos Eduardo Maia Gomes, Priya Duggal, Ingrid De Paula Holanda, Amanda Samara de Lima, Paulo Ricardo Porfírio do Nascimento, Selma Maria Bezerra Jeronimo

Sci Rep. 2021; 11: 6764. Published online 2021 Mar 24. doi: 10.1038/s41598-021-86240-z

PMCID:: PMC7990956

Abstract Article PDF–1.1M

Select item 798052813.

ERAPs Reduce In Vitro HIV Infection by Activating Innate Immune Response

Irma Saulle, Ivana Marventano, Marina Saresella, Claudia Vanetti, Micaela Garziano, Claudio Fenizia, Daria Trabattoni, Mario Clerici, Mara Biasin

J Immunol. 2021 Apr 1; 206(7): 1609–1617. Published online 2021 Feb 22. doi: 10.4049/jimmunol.2000991

PMCID:: PMC7980528

Abstract Article PDF–740K

Select item 795031614.

ERAP2 Increases the Abundance of a Peptide Submotif Highly Selective for the Birdshot Uveitis-Associated HLA-A29

Wouter J. Venema, Sanne Hiddingh, Joke H. de Boer, Frans H. J. Claas, Arend Mulder, Anneke I. den Hollander, Efstratios Stratikos, Siranush Sarkizova, Lars T. van der Veken, George M. C. Janssen, Peter A. van Veelen, Jonas J. W. Kuiper

Front Immunol. 2021; 12: 634441. Published online 2021 Feb 25. doi: 10.3389/fimmu.2021.634441

PMCID:: PMC7950316

Abstract Article PDF–3.8M

Select item 756352215.

A New ERAP2/Iso3 Isoform Expression Is Triggered by Different Microbial Stimuli in Human Cells. Could It Play a Role in the Modulation of SARS-CoV-2 Infection?

Irma Saulle, Claudia Vanetti, Sara Goglia, Chiara Vicentini, Enrico Tombetti, Micaela Garziano, Mario Clerici, Mara Biasin

Cells. 2020 Sep; 9(9): 1951. Published online 2020 Aug 24. doi: 10.3390/cells9091951

PMCID:: PMC7563522

Abstract Article PDF–1.8M

Select item 752525216.

Association of ERAP2 polymorphisms in Colombian HLA-B27+ or HLA-B15+ patients with SpA and its relationship with clinical presentation: axial or peripheral predominance

John Londono, Ana M Santos, Juan C Rueda, Enrique Calvo-Paramo, Ruben Burgos-Vargas, Gilberto Vargas-Alarcon, Nancy Martinez-Rodriguez, Sofia Arias-Correal, Guisselle-Nathalia Muñoz, Diana Padilla, Francy Cuervo, Viviana Reyes-Martinez, Santiago Bernal-Macías, Catalina Villota-Eraso, Luz M Avila-Portillo, Consuelo Romero, Juan F Medina

RMD Open. 2020; 6(2): e001250. Published online 2020 Sep 11. doi: 10.1136/rmdopen-2020-001250

PMCID:: PMC7525252

Abstract Article PDF–493K

Select item 739249117.

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination

Gangliang Wang, Shuai Chen, Ziang Xie, Shuying Shen, Wenbin Xu, Wenxiang Chen, Xiang Li, Yizheng Wu, Liangping Li, Bin Liu, Xianjun Ding, An Qin, Shunwu Fan

Ann Rheum Dis. 2020 Aug; 79(8): 1111–1120. Published online 2020 May 14. doi: 10.1136/annrheumdis-2019-216911

PMCID:: PMC7392491

Abstract Article PDF–14M

Select item 732206718.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 726181519.

Modulation of Natural HLA-B*27:05 Ligandome by Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 2 (ERAP2)

Elena Lorente, Miguel G. Fontela, Eilon Barnea, Antonio J. Martín-Galiano, Carmen Mir, Begoña Galocha, Arie Admon, Pilar Lauzurica, Daniel López

Mol Cell Proteomics. 2020 Jun; 19(6): 994–1004. Published online 2020 Apr 7. doi: 10.1074/mcp.RA120.002014

PMCID:: PMC7261815

Abstract Article PDF–1006K

Select item 717871920.

Polymorphisms in endoplasmic reticulum aminopeptidase genes are associated with cervical cancer risk in a Chinese Han population

Chuanyin Li, Yaheng Li, Zhiling Yan, Shuying Dai, Shuyuan Liu, Xia Wang, Jun Wang, Xinwen Zhang, Li Shi, Yufeng Yao

BMC Cancer. 2020; 20: 341. Published online 2020 Apr 22. doi: 10.1186/s12885-020-06832-2

PMCID:: PMC7178719

Abstract Article PDF–539K

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