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Items: 1 to 20 of 423

1.
The role of RUNX1/NF-κB in regulating PVAT inflammation in aortic dissection
Ao Wang, Shengjun Dong, Baohui Liu, Dianxiao Liu, Mingrui Zou, Yuexin Han, Lijuan Yang, Yujiu Wang
Sci Rep. 2024; 14: 9960. Published online 2024 Apr 30. doi: 10.1038/s41598-024-60737-9
PMCID:
PMC11063189
AbstractArticlePDF–4.8M
2.
TANGO6 regulates cell proliferation via COPI vesicle-mediated RPB2 nuclear entry
Zhi Feng, Shengnan Liu, Ming Su, Chunyu Song, Chenyu Lin, Fangying Zhao, Yang Li, Xianyan Zeng, Yong Zhu, Yu Hou, Chunguang Ren, Huan Zhang, Ping Yi, Yong Ji, Chao Wang, Hongtao Li, Ming Ma, Lingfei Luo, Li Li
Nat Commun. 2024; 15: 2371. Published online 2024 Mar 15. doi: 10.1038/s41467-024-46720-y
PMCID:
PMC10943085
AbstractArticlePDF–6.1M
3.
Autophagy regulates the maturation of hematopoietic precursors in the embryo
Yumin Liu, Linjuan Shi, Yifan Chen, Sifan Luo, Yuehang Chen, Hongtian Chen, Wenlang Lan, Xun Lu, Zhan Cao, Zehua Ye, Jinping Li, Bo Yu, Elaine Dzierzak, Zhuan Li
Nat Commun. 2024; 15: 2255. Published online 2024 Mar 15. doi: 10.1038/s41467-024-46453-y
PMCID:
PMC10943005
AbstractArticlePDF–6.4M
4.
Runt-related transcription factor-1 ameliorates bile acid–induced hepatic inflammation in cholestasis through JAK/STAT3 signaling
Liangjun Zhang, Qiong Pan, Lu Zhang, Haihan Xia, Junwei Liao, Xiaoxun Zhang, Nan Zhao, Qiaoling Xie, Min Liao, Ya Tan, Qiao Li, Jinfei Zhu, Ling Li, Shijun Fan, Jianwei Li, Chengcheng Zhang, Shi-Ying Cai, James L. Boyer, Jin Chai
Hepatology. Author manuscript; available in PMC 2024 Mar 8.
Published in final edited form as: Hepatology. 2023 Jun 1; 77(6): 1866–1881. Published online 2023 Jan 3. doi: 10.1097/HEP.0000000000000041
PMCID:
PMC10921919
AbstractArticlePDF–3.1M
5.
Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon
Jorge O. Múnera, Daniel O. Kechele, Carine Bouffi, Na Qu, Ran Jing, Pritiprasanna Maity, Jacob R. Enriquez, Lu Han, Ian Campbell, Maxime M. Mahe, Heather A. McCauley, Xinghao Zhang, Nambirajan Sundaram, Jonathan R. Hudson, Adrian Zarsozo-Lacoste, Suman Pradhan, Kentaro Tominaga, J. Guillermo Sanchez, Alison A. Weiss, Praneet Chatuvedi, Jason R. Spence, Mariam Hachimi, Trista North, George Q. Daley, Christopher N. Mayhew, Yueh-Chiang Hu, Takanori Takebe, Michael A. Helmrath, James M. Wells
Cell Stem Cell. Author manuscript; available in PMC 2024 Mar 5.
Published in final edited form as: Cell Stem Cell. 2023 Nov 2; 30(11): 1434–1451.e9. doi: 10.1016/j.stem.2023.10.002
PMCID:
PMC10913028
AbstractArticlePDF–4.3M
6.
A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis
Pengfei Guo, Rebecca C Lim, Keshari Rajawasam, Tiffany Trinh, Hong Sun, Hui Zhang
eLife. 2024; 13: e86168. Published online 2024 Feb 12. doi: 10.7554/eLife.86168
PMCID:
PMC10901513
AbstractArticlePDF–9.2M
7.
Runx1+ vascular smooth muscle cells are essential for hematopoietic stem and progenitor cell development in vivo
Zaniah N. Gonzalez Galofre, Alastair M. Kilpatrick, Madalena Marques, Diana Sá da Bandeira, Telma Ventura, Mario Gomez Salazar, Léa Bouilleau, Yvan Marc, Ana B. Barbosa, Fiona Rossi, Mariana Beltran, Harmen J. G. van de Werken, Wilfred F. J. van IJcken, Neil C. Henderson, Stuart J. Forbes, Mihaela Crisan
Nat Commun. 2024; 15: 1653. Published online 2024 Feb 23. doi: 10.1038/s41467-024-44913-z
PMCID:
PMC10891074
AbstractArticlePDF–30M
8.
PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development
Jong Geol Lee, Jung-Min Yon, Globinna Kim, Seul-Gi Lee, C-Yoon Kim, Seung-A Cheong, Hyun-Yi Kim, Jiyoung Yu, Kyunggon Kim, Young Hoon Sung, Hyun Ju Yoo, Dong-Cheol Woo, Jin Kyung Rho, Chang Hoon Ha, Chan-Gi Pack, Seak Hee Oh, Joon Seo Lim, Yu Mi Han, Eui-Ju Hong, Je Kyung Seong, Han-Woong Lee, Sang-Wook Lee, Ki-Up Lee, Chong Jai Kim, Sang-Yoon Nam, You Sook Cho, In-Jeoung Baek
Nat Commun. 2024; 15: 1487. Published online 2024 Feb 19. doi: 10.1038/s41467-024-45647-8
PMCID:
PMC10876648
AbstractArticlePDF–10M
9.
Ribonucleicacid interference or small molecule inhibition of Runx1 in the border zone prevents cardiac contractile dysfunction following myocardial infarction
Tamara P Martin, Eilidh A MacDonald, Ashley Bradley, Holly Watson, Priyanka Saxena, Eva A Rog-Zielinska, Anmar Raheem, Simon Fisher, Ali Ali Mohamed Elbassioni, Ohood Almuzaini, Catriona Booth, Morna Campbell, Alexandra Riddell, Pawel Herzyk, Karen Blyth, Colin Nixon, Lorena Zentilin, Colin Berry, Thomas Braun, Mauro Giacca, Martin W McBride, Stuart A Nicklin, Ewan R Cameron, Christopher M Loughrey
Cardiovasc Res. 2023 Nov; 119(16): 2663–2671. Published online 2023 Jul 11. doi: 10.1093/cvr/cvad107
PMCID:
PMC10730241
AbstractArticlePDF–8.6M
10.
Runx1-R188Q germ line mutation induces inflammation and predisposition to hematologic malignancies in mice
Mohd Hafiz Ahmad, Mahesh Hegde, Waihay J. Wong, Mona Mohammadhosseini, Lisa Garrett, Anneliese Carrascoso, Neethu Issac, Benjamin Ebert, Jeffrey C. Silva, German Pihan, Lihua J. Zhu, Scot A. Wolfe, Anupriya Agarwal, P. Paul Liu, Lucio H. Castilla
Blood Adv. 2023 Dec 12; 7(23): 7304–7318. Published online 2023 Sep 28. doi: 10.1182/bloodadvances.2023010398
PMCID:
PMC10711191
AbstractArticlePDF–3.1M
11.
Tumor cell-released kynurenine biases MEP differentiation into megakaryocytes in individuals with cancer by activating AhR–RUNX1
Li Zhou, Dongxiao Wu, Yabo Zhou, Dianheng Wang, Haixia Fu, Qiusha Huang, Guohui Qin, Jie Chen, Jiadi Lv, Shaoyang Lai, Huafeng Zhang, Ke Tang, Jingwei Ma, Roland Fiskesund, Yi Zhang, Xiaohui Zhang, Bo Huang
Nat Immunol. 2023; 24(12): 2042–2052. Published online 2023 Nov 2. doi: 10.1038/s41590-023-01662-3
Correction in:
Nat Immunol. 2023; 24(12): 2165.
PMCID:
PMC10681900
AbstractArticlePDF–6.4M
12.
Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia
Simon Vermeiren, Pauline Cabochette, Maya Dannawi, Simon Desiderio, Alba Sabaté San José, Younes Achouri, Sadia Kricha, Maren Sitte, Gabriela Salinas-Riester, Benoit Vanhollebeke, Jean-François Brunet, Eric J. Bellefroid
iScience. 2023 Dec 15; 26(12): 108364. Published online 2023 Oct 31. doi: 10.1016/j.isci.2023.108364
PMCID:
PMC10663820
AbstractArticlePDF–5.8M
13.
RUNX1 facilitates heart failure progression through regulating TGF-β-induced cardiac remodeling
Peng Qi, Qian Zhai, Xiquan Zhang
PeerJ. 2023; 11: e16202. Published online 2023 Oct 31. doi: 10.7717/peerj.16202
PMCID:
PMC10624168
AbstractArticlePDF–33M
14.
Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function
Lorenzo M. Fernandes, Jeffrey Tresemer, Jing Zhang, Jonathan J. Rios, Joshua P. Scallan, Michael T. Dellinger
Front Cell Dev Biol. 2023; 11: 1276333. Published online 2023 Sep 25. doi: 10.3389/fcell.2023.1276333
PMCID:
PMC10571159
AbstractArticlePDF–14M
15.
RUNX1 is required in granulocyte–monocyte progenitors to attenuate inflammatory cytokine production by neutrophils
Alexandra U. Zezulin, Daniel Yen, Darwin Ye, Elizabeth D. Howell, Erica Bresciani, Jamie Diemer, Jian-gang Ren, Mohd Hafiz Ahmad, Lucio H. Castilla, Ivo P. Touw, Andy J. Minn, Wei Tong, P. Paul Liu, Kai Tan, Wenbao Yu, Nancy A. Speck
Genes Dev. 2023 Jul 1; 37(13-14): 605–620. doi: 10.1101/gad.350418.123
PMCID:
PMC10499021
AbstractArticlePDF–3.5M
16.
RNA binding protein IGF2BP1 synergizes with ETV6-RUNX1 to drive oncogenic signaling in B-cell Acute Lymphoblastic Leukemia
Gunjan Sharma, Tiffany M. Tran, Ishu Bansal, Mohammad Sabique Beg, Ruchi Bhardwaj, Jaspal Bassi, Yuande Tan, Amit Kumar Jaiswal, Christine Tso, Ayushi Jain, Jay Singh, Parthaprasad Chattopadhyay, Archna Singh, Anita Chopra, Sameer Bakhshi, David Casero, Dinesh S. Rao, Jayanth Kumar Palanichamy
J Exp Clin Cancer Res. 2023; 42: 231. Published online 2023 Sep 5. doi: 10.1186/s13046-023-02810-1
PMCID:
PMC10478443
AbstractArticlePDF–12M
17.
GATA2 mitotic bookmarking is required for definitive haematopoiesis
Rita Silvério-Alves, Ilia Kurochkin, Anna Rydström, Camila Vazquez Echegaray, Jakob Haider, Matthew Nicholls, Christina Rode, Louise Thelaus, Aida Yifter Lindgren, Alexandra Gabriela Ferreira, Rafael Brandão, Jonas Larsson, Marella F. T. R. de Bruijn, Javier Martin-Gonzalez, Carlos-Filipe Pereira
Nat Commun. 2023; 14: 4645. Published online 2023 Aug 14. doi: 10.1038/s41467-023-40391-x
PMCID:
PMC10425459
AbstractArticlePDF–4.8M
18.
Meis1 establishes the pre-hemogenic endothelial state prior to Runx1 expression
Patrick Coulombe, Grace Cole, Amanda Fentiman, Jeremy D. K. Parker, Eric Yung, Misha Bilenky, Lemlem Degefie, Patrick Lac, Maggie Y. M. Ling, Derek Tam, R. Keith Humphries, Aly Karsan
Nat Commun. 2023; 14: 4537. Published online 2023 Jul 27. doi: 10.1038/s41467-023-40283-0
PMCID:
PMC10374625
AbstractArticlePDF–8.8M
19.
RUNX1 promotes liver fibrosis progression through regulating TGF‐β signalling
Zhaoyang Guo, Xinxin Liu, Shulei Zhao, Fengkai Sun, Wanhua Ren, Mingze Ma
Int J Exp Pathol. 2023 Aug; 104(4): 188–198. Published online 2023 Apr 17. doi: 10.1111/iep.12474
PMCID:
PMC10349244
AbstractArticlePDF–8.6M
20.
Progesterone receptor mediates ovulatory transcription through RUNX transcription factor interactions and chromatin remodelling
Doan T Dinh, James Breen, Barbara Nicol, Natalie J Foot, David C Bersten, Alaknanda Emery, Kirsten M Smith, Ying Y Wong, Simon C Barry, Humphrey H C Yao, Rebecca L Robker, Darryl L Russell
Nucleic Acids Res. 2023 Jul 7; 51(12): 5981–5996. Published online 2023 Apr 26. doi: 10.1093/nar/gkad271
PMCID:
PMC10325896
AbstractArticlePDF–2.0M

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