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Items: 1 to 20 of 75

1.
Human cytomegalovirus UL138 interaction with USP1 activates STAT1 in infection
Kristen Zarrella, Pierce Longmire, Sebastian Zeltzer, Donna Collins-McMillen, Meaghan Hancock, Jason Buehler, Justin M. Reitsma, Scott S. Terhune, Jay A. Nelson, Felicia Goodrum
PLoS Pathog. 2023 Jun; 19(6): e1011185. Published online 2023 Jun 8. doi: 10.1371/journal.ppat.1011185
PMCID:
PMC10284425
AbstractArticlePDF–3.3M
2.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
3.
Inhibition of USP1 reverses the chemotherapy resistance through destabilization of MAX in the relapsed/refractory B-cell lymphoma
Xi-Ya Li, Ji-Chuan Wu, Ping Liu, Zi-Juan Li, Yong Wang, Bing-Yi Chen, Cheng-Long Hu, Ming-Yue Fei, Peng-Cheng Yu, Yi-Lun Jiang, Chun-Hui Xu, Bin-He Chang, Xin-Chi Chen, Li-Juan Zong, Jia-Ying Zhang, Ying Fang, Xiao-Jian Sun, Kai Xue, Li Wang, Shu-Bei Chen, Shi-Yu Jiang, Ai-ling Gui, Ling Yang, Juan J. Gu, Bao-Hua Yu, Qun-ling Zhang, Lan Wang
Leukemia. 2023; 37(1): 164–177. Published online 2022 Nov 9. doi: 10.1038/s41375-022-01747-2
PMCID:
PMC9883169
AbstractArticlePDF–6.6M
4.
WD repeat domain 48 promotes hepatocellular carcinoma progression by stabilizing c‐Myc
Bo Li, Ye‐wei Zhang, Kun Cao, Chao Li, Qian Chen, Yi‐heng Jiang, Lu‐ling Luo, Shi Zuo
J Cell Mol Med. 2022 Dec; 26(23): 5755–5766. Published online 2022 Nov 20. doi: 10.1111/jcmm.17583
PMCID:
PMC9716212
AbstractArticlePDF–32M
5.
A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation
Yulemi Gonzalez Quesada, Luc DesGroseillers
Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588
PMCID:
PMC9569955
AbstractArticlePDF–2.1M
6.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
7.
UBE2T regulates FANCI monoubiquitination to promote NSCLC progression by activating EMT
Jiguang Zhang, Jingdong Wang, Jincheng Wu, Jianyuan Huang, Zhaoxian Lin, Xing Lin
Oncol Rep. 2022 Aug; 48(2): 139. Published online 2022 Jun 14. doi: 10.3892/or.2022.8350
PMCID:
PMC9245069
AbstractArticlePDF–3.2M
8.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
9.
A protein interaction landscape of breast cancer
Minkyu Kim, Jisoo Park, Mehdi Bouhaddou, Kyumin Kim, Ajda Rojc, Maya Modak, Margaret Soucheray, Michael J. McGregor, Patrick O’Leary, Denise Wolf, Erica Stevenson, Tzeh Keong Foo, Dominique Mitchell, Kari A. Herrington, Denise P. Muñoz, Beril Tutuncuoglu, Kuei-Ho Chen, Fan Zheng, Jason F. Kreisberg, Morgan E. Diolaiti, John D. Gordan, Jean-Philippe Coppé, Danielle L. Swaney, Bing Xia, Laura van ’t Veer, Alan Ashworth, Trey Ideker, Nevan Krogan
Science. Author manuscript; available in PMC 2022 Apr 26.
Published in final edited form as: Science. 2021 Oct; 374(6563): eabf3066. Published online 2021 Oct 1. doi: 10.1126/science.abf3066
PMCID:
PMC9040556
AbstractArticlePDF–2.2M
10.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
11.
USP1-dependent RPS16 protein stability drives growth and metastasis of human hepatocellular carcinoma cells
Yuning Liao, Zhenlong Shao, Yuan Liu, Xiaohong Xia, Yuanfei Deng, Cuifu Yu, Wenshuang Sun, Weiyao Kong, Xiaoyue He, Fang Liu, Zhiqiang Guo, Guoxing Chen, Daolin Tang, Huoye Gan, Jinbao Liu, Hongbiao Huang
J Exp Clin Cancer Res. 2021; 40: 201. Published online 2021 Jun 21. doi: 10.1186/s13046-021-02008-3
PMCID:
PMC8215741
AbstractArticlePDF–6.8M
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch
Agnieszka T. Kawashima, Cassandra Wong, Gema Lordén, Charles C. King, Pablo Lara-Gonzalez, Arshad Desai, Anne-Claude Gingras, Alexandra C. Newton
Mol Cell Biol. 2021 Mar; 41(3): e00333-20. Prepublished online 2021 Jan 4. Published online 2021 Feb 23. doi: 10.1128/MCB.00333-20
PMCID:
PMC8088274
AbstractArticlePDF–3.1M
14.
A conserved acetylation switch enables pharmacological control of tubby-like protein stability
Evan M. Kerek, Kevin H. Yoon, Shu Y. Luo, Jerry Chen, Robert Valencia, Olivier Julien, Andrew J. Waskiewicz, Basil P. Hubbard
J Biol Chem. 2021 Jan-Jun; 296: 100073. Published online 2020 Nov 23. doi: 10.1074/jbc.RA120.015839
PMCID:
PMC7948452
AbstractArticlePDF–3.6M
15.
USP1-WDR48 deubiquitinase complex enhances TGF-β induced epithelial–mesenchymal transition of TNBC cells via stabilizing TAK1
Dianwen Han, Lijuan Wang, Bing Chen, Wenjing Zhao, Yiran Liang, Yaming Li, Hanwen Zhang, Ying Liu, Xiaolong Wang, Tong Chen, Chen Li, Xiaojin Song, Dan Luo, Zheng Li, Qifeng Yang
Cell Cycle. 2021; 20(3): 320–331. Published online 2021 Jan 18. doi: 10.1080/15384101.2021.1874695
PMCID:
PMC7889205
AbstractArticlePDF–11M
16.
Comprehensive analysis of ubiquitin‐specific protease 1 reveals its importance in hepatocellular carcinoma
Yalei Zhao, Chen Xue, Zhongyang Xie, Xiaoxi Ouyang, Lanjuan Li
Cell Prolif. 2020 Oct; 53(10): e12908. Published online 2020 Sep 19. doi: 10.1111/cpr.12908
PMCID:
PMC7574869
AbstractArticlePDF–3.3M
17.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
18.
ATAD5 suppresses centrosome over-duplication by regulating UAF1 and ID1
Seong-jung Kim, Minwoo Wie, Su Hyung Park, Tae Moon Kim, Jun Hong Park, Shinseog Kim, Kyungjae Myung, Kyoo-young Lee
Cell Cycle. 2020; 19(15): 1952–1968. Published online 2020 Jun 28. doi: 10.1080/15384101.2020.1785724
PMCID:
PMC7469630
AbstractArticlePDF–9.4M
19.
The WD40-repeat protein WDR-48 promotes the stability of the deubiquitinating enzyme USP-46 by inhibiting its ubiquitination and degradation
Molly Hodul, Rakesh Ganji, Caroline L. Dahlberg, Malavika Raman, Peter Juo
J Biol Chem. 2020 Aug 14; 295(33): 11776–11788. Published online 2020 Jun 25. doi: 10.1074/jbc.RA120.014590
PMCID:
PMC7450142
AbstractArticlePDF–1.6M
20.
The DNA-binding activity of USP1-associated factor 1 is required for efficient RAD51-mediated homologous DNA pairing and homology-directed DNA repair
Fengshan Liang, Adam S. Miller, Caroline Tang, David Maranon, Elizabeth A. Williamson, Robert Hromas, Claudia Wiese, Weixing Zhao, Patrick Sung, Gary M. Kupfer
J Biol Chem. 2020 Jun 12; 295(24): 8186–8194. Published online 2020 Apr 29. doi: 10.1074/jbc.RA120.013714
PMCID:
PMC7294083
AbstractArticlePDF–2.0M

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