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Select item 91063031.

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors

Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen

Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638

PMCID:: PMC9106303

Abstract Article PDF–918K

Select item 88574852.

Prostate secretory protein 94 inhibits sterol binding and export by the mammalian CAP protein CRISP2 in a calcium-sensitive manner

Ola El Atab, Aslihan Ekim Kocabey, Oluwatoyin A. Asojo, Roger Schneiter

J Biol Chem. 2022 Mar; 298(3): 101600. Published online 2022 Jan 19. doi: 10.1016/j.jbc.2022.101600

PMCID:: PMC8857485

Abstract Article PDF–2.2M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77969964.

Validation of prostate cancer risk variants rs10993994 and rs7098889 by CRISPR/Cas9 mediated genome editing

Xing Wang, James E. Hayes, Xing Xu, Xiaoni Gao, Dipti Mehta, Hans G. Lilja, Robert J. Klein

Gene. Author manuscript; available in PMC 2022 Feb 5.

Published in final edited form as: Gene. 2021 Feb 5; 768: 145265. Published online 2020 Oct 26. doi: 10.1016/j.gene.2020.145265

PMCID:: PMC7796996

Abstract Article PDF–1.6M

Select item 65944525.

The role of plasma microseminoprotein-beta in prostate cancer: an observational nested case–control and Mendelian randomization study in the European prospective investigation into cancer and nutrition

K Smith Byrne, P N Appleby, T J Key, M V Holmes, G K Fensom, A Agudo, E Ardanaz, H Boeing, H B Bueno-de-Mesquita, M D Chirlaque, R Kaaks, N Larrañaga, D Palli, A Perez-Cornago, J R Quirós, F Ricceri, M J Sánchez, G Tagliabue, K K Tsilidis, R Tumino, R T Fortner, P Ferrari, PRACTICAL Consortium, E Riboli, H Lilja, R C Travis

Ann Oncol. 2019 Jun; 30(6): 983–989. Published online 2019 Apr 8. doi: 10.1093/annonc/mdz121

PMCID:: PMC6594452

Abstract Article PDF–164K

Select item 54386676.

MSMB gene rs10993994 polymorphism increases the risk of prostate cancer

Tao Peng, Lifeng Zhang, Lijie Zhu, Yuan-Yuan Mi

Oncotarget. 2017 Apr 25; 8(17): 28494–28501. Published online 2017 Feb 14. doi: 10.18632/oncotarget.15312

PMCID:: PMC5438667

Abstract Article PDF–2.3M

Select item 48518617.

Evidence for an Association Between Prostate Cancer and Chromosome 8q24 and10q11 Genetic Variants in African American Men: The Flint Men's Health Study

Yunfei Wang, Anna M. Ray, Emilie K. Johnson, Kimberly A. Zuhlke, Kathleen A. Cooney, Ethan M. Lange

Prostate. Author manuscript; available in PMC 2016 Apr 30.

Published in final edited form as: Prostate. 2011 Feb 15; 71(3): 225–231. Published online 2010 Aug 17. doi: 10.1002/pros.21234

PMCID:: PMC4851861

Abstract Article PDF–116K

Select item 47773738.

Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer

Liisa Sjöblom, Outi Saramäki, Matti Annala, Katri Leinonen, Janika Nättinen, Teemu Tolonen, Tiina Wahlfors, Matti Nykter, G. Steven Bova, Johanna Schleutker, Teuvo L. J. Tammela, Hans Lilja, Tapio Visakorpi

PLoS One. 2016; 11(3): e0150241. Published online 2016 Mar 3. doi: 10.1371/journal.pone.0150241

Correction in:: PLoS One. 2016; 11(4): e0153732.

PMCID:: PMC4777373

Abstract Article PDF–822K

Select item 45402049.

PSP94, an upstream signaling mediator of prostasin found highly elevated in ovarian cancer

J-x Ma, B-x Yan, J Zhang, B-H Jiang, Y Guo, H Riedel, M D Mueller, S C Remick, J J Yu

Cell Death Dis. 2014 Sep; 5(9): e1407. Published online 2014 Sep 4. doi: 10.1038/cddis.2014.374

PMCID:: PMC4540204

Abstract Article PDF–1.0M

Select item 426658810.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 408240511.

Genetic variation in protein specific antigen detected prostate cancer and the effect of control selection on genetic association studies

Duleeka W Knipe, David M Evans, John P. Kemp, Rosalind Eeles, Douglas F Easton, Zsofia Kote-Jarai, Ali Amin Al Olama, Sara Benlloch, Jenny L. Donovan, Freddie C. Hamdy, David E Neal, George Davey Smith, Mark Lathrop, Richard M Martin

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2015 Jan 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2014 Jul; 23(7): 1356–1365. Published online 2014 Apr 21. doi: 10.1158/1055-9965.EPI-13-0889

PMCID:: PMC4082405

Abstract Article PDF–1.0M

Select item 399283512.

MSMB gene variant alters the association between prostate cancer and number of sexual partners

Marni Stott-Miller, Jonathan L. Wright, Janet L. Stanford

Prostate. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: Prostate. 2013 Dec; 73(16): 1803–1809. Published online 2013 Aug 23. doi: 10.1002/pros.22719

PMCID:: PMC3992835

Abstract Article PDF–289K

Select item 398917113.

Genome-Wide Association Scan for Variants Associated with Early-Onset Prostate Cancer

Ethan M. Lange, Anna M. Johnson, Yunfei Wang, Kimberly A. Zuhlke, Yurong Lu, Jessica V. Ribado, Gregory R. Keele, Jin Li, Qing Duan, Ge Li, Zhengrong Gao, Yun Li, Jianfeng Xu, William B. Isaacs, Siqun Zheng, Kathleen A. Cooney

PLoS One. 2014; 9(4): e93436. Published online 2014 Apr 16. doi: 10.1371/journal.pone.0093436

PMCID:: PMC3989171

Abstract Article PDF–334K

Select item 395631714.

Promoter variants in the MSMB gene associated with prostate cancer regulate MSMB/NCOA4 fusion transcripts

Hong Lou, Hongchuan Li, Meredith Yeager, Kate Im, Bert Gold, Thomas D. Schneider, Joseph F. Fraumeni, Jr., Stephen J. Chanock, Stephen K. Anderson, Michael Dean

Hum Genet. Author manuscript; available in PMC 2014 Mar 17.

Published in final edited form as: Hum Genet. 2012 Sep; 131(9): 1453–1466. Published online 2012 Jun 4. doi: 10.1007/s00439-012-1182-2

PMCID:: PMC3956317

Abstract Article PDF–2.3M

Select item 373931815.

Growth inhibition mediated by PSP94 or CRISP-3 is prostate cancer cell line specific

Bhakti R. Pathak, Ananya A. Breed, Vaishali H. Nakhawa, Dhanashree D. Jagtap, Smita D. Mahale

Asian J Androl. 2010 Sep; 12(5): 677–689. Published online 2010 Aug 2. doi: 10.1038/aja.2010.56

PMCID:: PMC3739318

Abstract Article PDF–811K

Select item 373200916.

Susceptibility Loci Associated with Prostate Cancer Progression and Mortality

David J. Gallagher, Joseph Vijai, Angel M. Cronin, Jasmine Bhatia, Andrew J. Vickers, Mia M. Gaudet, Samson Fine, Victor Reuter, Howard I. Scher, Christer Halldén, Ana Dutra-Clarke, Robert J. Klein, Peter T. Scardino, James A. Eastham, Hans Lilja, Tomas Kirchhoff, Kenneth Offit

Clin Cancer Res. Author manuscript; available in PMC 2013 Aug 2.

Published in final edited form as: Clin Cancer Res. 2010 May 15; 16(10): 2819–2832. Published online 2010 May 11. doi: 10.1158/1078-0432.CCR-10-0028

PMCID:: PMC3732009

Abstract Article PDF–683K

Select item 361291617.

Genome-wide Association Study Identifies Genetic Determinants of Urine PCA3 Levels in Men

Zhuo Chen, Jielin Sun, Seong-Tae Kim, Jack Groskopf, Junjie Feng, William B Isaacs, Roger S Rittmaster, Lynn D Condreay, Siqun Lilly Zheng, Jianfeng Xu

Neoplasia. 2013 Apr; 15(4): 448–453. doi: 10.1593/neo.122144

PMCID:: PMC3612916

Abstract Article PDF–455K

Select item 356458118.

Genetic correction of PSA values using sequence variants associated with PSA levels

Julius Gudmundsson, Soren Besenbacher, Patrick Sulem, Daniel F. Gudbjartsson, Isleifur Olafsson, Sturla Arinbjarnarson, Bjarni A. Agnarsson, Kristrun R. Benediktsdottir, Helgi J. Isaksson, Jelena P. Kostic, Sigurjon A. Gudjonsson, Simon N. Stacey, Arnaldur Gylfason, Asgeir Sigurdsson, Hilma Holm, Unnur S. Bjornsdottir, Gudmundur I. Eyjolfsson, Sebastian Navarrete, Fernando Fuertes, Maria D. Garcia-Prats, Eduardo Polo, Ionel A. Checherita, Mariana Jinga, Paula Badea, Katja K. Aben, Jack A. Schalken, Inge M. van Oort, Fred C. Sweep, Brian T. Helfand, Michael Davis, Jenny L. Donovan, Freddie C. Hamdy, Kristleifur Kristjansson, Jeffrey R. Gulcher, Gisli Masson, Augustine Kong, William J. Catalona, Jose I. Mayordomo, Gudmundur Geirsson, Gudmundur V. Einarsson, Rosa B. Barkardottir, Eirikur Jonsson, Viorel Jinga, Dana Mates, Lambertus A. Kiemeney, David E. Neal, Unnur Thorsteinsdottir, Thorunn Rafnar, Kari Stefansson

Sci Transl Med. Author manuscript; available in PMC 2013 Feb 5.

Published in final edited form as: Sci Transl Med. 2010 Dec 15; 2(62): 62ra92. doi: 10.1126/scitranslmed.3001513

PMCID:: PMC3564581

Abstract Article PDF–397K

Select item 353295719.

Investigation of the relationship between prostate cancer and MSMB and NCOA4 genetic variants and protein expression

Liesel M. FitzGerald, Xiaotun Zhang, Suzanne Kolb, Erika M. Kwon, Ying Ching Liew, Antonio Hurtado-Coll, Beatrice S. Knudsen, Elaine A. Ostrander, Janet L. Stanford

Hum Mutat. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Hum Mutat. 2013 Jan; 34(1): 149–156. Published online 2012 Oct 4. doi: 10.1002/humu.22176

PMCID:: PMC3532957

Abstract Article PDF–1.1M

Select item 335326920.

Established Prostate Cancer Susceptibility Variants are not Associated with Disease Outcome

Fredrik E. Wiklund, Hans-Olov Adami, Sigun L. Zheng, Pär Stattin, William B. Isaacs, Henrik Grönberg, Jianfeng Xu

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2012 May 16.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2009 May; 18(5): 1659–1662. doi: 10.1158/1055-9965.EPI-08-1148

PMCID:: PMC3353269

Abstract Article PDF–40K

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