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Items: 1 to 20 of 82

1.
Start codon variant in LAG3 is associated with decreased LAG-3 expression and increased risk of autoimmune thyroid disease
Saedis Saevarsdottir, Kristbjörg Bjarnadottir, Thorsteinn Markusson, Jonas Berglund, Thorunn A. Olafsdottir, Gisli H. Halldorsson, Gudrun Rutsdottir, Kristbjorg Gunnarsdottir, Asgeir Orn Arnthorsson, Sigrun H. Lund, Lilja Stefansdottir, Julius Gudmundsson, Ari J. Johannesson, Arni Sturluson, Asmundur Oddsson, Bjarni Halldorsson, Björn R. Ludviksson, Egil Ferkingstad, Erna V. Ivarsdottir, Gardar Sveinbjornsson, Gerdur Grondal, Gisli Masson, Grimur Hjorleifsson Eldjarn, Gudmundur A. Thorisson, Katla Kristjansdottir, Kirk U. Knowlton, Kristjan H. S. Moore, Sigurjon A. Gudjonsson, Solvi Rognvaldsson, Stacey Knight, Lincoln D. Nadauld, Hilma Holm, Olafur T. Magnusson, Patrick Sulem, Daniel F. Gudbjartsson, Thorunn Rafnar, Gudmar Thorleifsson, Pall Melsted, Gudmundur L. Norddahl, Ingileif Jonsdottir, Kari Stefansson
Nat Commun. 2024; 15: 5748. Published online 2024 Jul 9. doi: 10.1038/s41467-024-50007-7
PMCID:
PMC11233504
AbstractArticlePDF–1.9M
2.
Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S. Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J. Workman, Dario A. A. Vignali, Ulrike C. Muller, Cong Liu, Han Seok Ko, Valina L. Dawson, Ted M. Dawson
Nat Commun. 2024; 15: 4663. Published online 2024 May 31. doi: 10.1038/s41467-024-49016-3
Correction in:
Nat Commun. 2024; 15: 6413.
PMCID:
PMC11143359
AbstractArticlePDF–3.3M
3.
Association of Polymorphisms in PD-1 and LAG-3 Genes with Acute Myeloid Leukemia
Lamjed Mansour, Mashael Alqahtani, Ali Aljuaimlani, Jameel Al-Tamimi, Nouf Al-Harbi, Suliman Alomar
Medicina (Kaunas) 2024 May; 60(5): 721. Published online 2024 Apr 26. doi: 10.3390/medicina60050721
PMCID:
PMC11123055
AbstractArticlePDF–2.7M
4.
Multiplex immunohistochemistry elucidates increased distance between cytotoxic T cells and plasma cells in relapsed myeloma, and identifies Lag-3 as the most common checkpoint receptor on cytotoxic T cells of myeloma patients
Slavisa Ninkovic, Louise E Purton, Simon J Harrison, Hang Quach
Haematologica. 2024 May 1; 109(5): 1487–1500. Published online 2023 Oct 19. doi: 10.3324/haematol.2023.283344
PMCID:
PMC11063850
AbstractArticlePDF–5.6M
5.
Blockade of PD-1 and LAG-3 expression on CD8+ T cells promotes the tumoricidal effects of CD8+ T cells
Jiajia Ma, Shufang Yan, Ying Zhao, Huifang Yan, Qian Zhang, Xinxia Li
Front Immunol. 2023; 14: 1265255. Published online 2023 Sep 28. doi: 10.3389/fimmu.2023.1265255
PMCID:
PMC10568325
AbstractArticlePDF–14M
6.
Comprehensive immunophenotyping of solid tumor-infiltrating immune cells reveals the expression characteristics of LAG-3 and its ligands
Bradley Garman, Can Jiang, Sherif Daouti, Sanah Kumar, Priyanka Mehta, Miye K. Jacques, Laurence Menard, Nataly Manjarrez-Orduno, Sonia Dolfi, Piali Mukherjee, Sharmila Chamling Rai, Ana Lako, Jennifer D. Koenitzer, Justin M. David
Front Immunol. 2023; 14: 1151748. Published online 2023 Sep 19. doi: 10.3389/fimmu.2023.1151748
PMCID:
PMC10546411
AbstractArticlePDF–7.5M
7.
A unique expression pattern of LAG3 distinct from that of other immune checkpoints in diffuse large B‐cell lymphoma
Hyunjee Lee, Sang Eun Yoon, Seok Jin Kim, Won Seog Kim, Junhun Cho
Cancer Med. 2023 Aug; 12(15): 16359–16369. Published online 2023 Jun 16. doi: 10.1002/cam4.6268
PMCID:
PMC10469648
AbstractArticlePDF–11M
8.
LAG3 in gastric cancer: it’s complicated
Dita Ulase, Hans-Michael Behrens, Sandra Krüger, Steffen M. Heckl, Ulrike Ebert, Thomas Becker, Christoph Röcken
J Cancer Res Clin Oncol. 2023; 149(12): 10797–10811. Published online 2023 Jun 14. doi: 10.1007/s00432-023-04954-1
PMCID:
PMC10423140
AbstractArticlePDF–2.0M
9.
LAG-3 expression in tumor microenvironment of triple-negative breast cancer
Gözde TAHTACI, Nazan GÜNEL, Aysu SADİOĞLU, Nalan AKYÜREK, Oğulcan BOZ, Aytuğ ÜNER
Turk J Med Sci. 2023; 53(1): 142–148. Published online 2022 Nov 20. doi: 10.55730/1300-0144.5567
PMCID:
PMC10388047
AbstractArticlePDF–347K
10.
LAG‐3 transcriptomic expression patterns across malignancies: Implications for precision immunotherapeutics
Jacob J. Adashek, Shumei Kato, Daisuke Nishizaki, Hirotaka Miyashita, Pradip De, Suzanna Lee, Sarabjot Pabla, Mary Nesline, Jeffrey M. Conroy, Paul DePietro, Scott Lippman, Razelle Kurzrock
Cancer Med. 2023 Jun; 12(12): 13155–13166. Published online 2023 May 3. doi: 10.1002/cam4.6000
PMCID:
PMC10315766
AbstractArticlePDF–772K
11.
Lymphocyte activation gene 3 is increased and affects cytokine production in rheumatoid arthritis
Janni Maria Pedersen, Aida Solhøj Hansen, Cæcilie Skejø, Kristian Juul-Madsen, Peter Junker, Kim Hørslev-Petersen, Merete Lund Hetland, Kristian Stengaard-Pedersen, Mikkel Østergaard, Bjarne Kuno Møller, Lene Dreyer, Ellen-Margrethe Hauge, Malene Hvid, Stinne Greisen, Bent Deleuran
Arthritis Res Ther. 2023; 25: 97. Published online 2023 Jun 7. doi: 10.1186/s13075-023-03073-z
PMCID:
PMC10246404
AbstractArticlePDF–2.6M
12.
LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition
Qianqian Ming, Daiana P. Celias, Chao Wu, Aidan R. Cole, Srishti Singh, Charlotte Mason, Shen Dong, Timothy H. Tran, Gaya K. Amarasinghe, Brian Ruffell, Vincent C. Luca
Nat Immunol. Author manuscript; available in PMC 2023 May 17.
Published in final edited form as: Nat Immunol. 2022 Jul; 23(7): 1031–1041. Published online 2022 Jun 27. doi: 10.1038/s41590-022-01238-7
PMCID:
PMC10191176
AbstractArticlePDF–4.3M
13.
Lymphocyte-activation gene 3 protein expression in tumor-infiltrating lymphocytes is associated with a poor prognosis of ovarian clear cell carcinoma
Sumika Zaitsu, Mitsutake Yano, Sawako Adachi, Maiko Miwa, Tomomi Katoh, Yasushi Kawano, Masanori Yasuda
J Ovarian Res. 2023; 16: 93. Published online 2023 May 13. doi: 10.1186/s13048-023-01179-1
PMCID:
PMC10182671
AbstractArticlePDF–1.8M
14.
Evaluation of the possible association of PDCD-1 and LAG3 gene polymorphisms with hepatocellular carcinoma risk
Jiankai Wei, Zhangxiu Liao, Ying Tao, Shuaiting Liu
BMC Med Genomics. 2023; 16: 92. Published online 2023 May 2. doi: 10.1186/s12920-023-01526-7
PMCID:
PMC10155321
AbstractArticlePDF–2.2M
15.
Searching for Biomarkers in the Blood of Patients at Risk of Developing Parkinson’s Disease at the Prodromal Stage
Elena A. Katunina, Victor Blokhin, Marina R. Nodel, Ekaterina N. Pavlova, Alexander L. Kalinkin, Valerian G. Kucheryanu, Leyla Alekperova, Marianna V. Selikhova, Mikhail Yu. Martynov, Michael V. Ugrumov
Int J Mol Sci. 2023 Feb; 24(3): 1842. Published online 2023 Jan 17. doi: 10.3390/ijms24031842
PMCID:
PMC9915927
AbstractArticlePDF–5.3M
16.
Lack of Association between Common LAG3/CD4 Variants and Risk of Migraine
Elena García-Martín, Santiago Navarro-Muñoz, Pedro Ayuso, Christopher Rodríguez, Mercedes Serrador, Hortensia Alonso-Navarro, Marisol Calleja, Francisco Navacerrada, Laura Turpín-Fenoll, Marta Recio-Bermejo, Rafael García-Ruiz, Jorge Millán-Pascual, José Francisco Plaza-Nieto, Esteban García-Albea, José A. G. Agúndez, Félix Javier Jiménez-Jiménez
Int J Mol Sci. 2023 Jan; 24(2): 1292. Published online 2023 Jan 9. doi: 10.3390/ijms24021292
PMCID:
PMC9866744
AbstractArticlePDF–270K
17.
LAG-3 Contribution to T Cell Downmodulation during Acute Respiratory Viral Infections
Linmar Rodríguez-Guilarte, Mario A. Ramírez, Catalina A. Andrade, Alexis M. Kalergis
Viruses. 2023 Jan; 15(1): 147. Published online 2023 Jan 3. doi: 10.3390/v15010147
PMCID:
PMC9865459
AbstractArticlePDF–1.5M
18.
Association between LAG3/CD4 gene variants and risk of Parkinson's disease
Elena García‐Martín, Pau Pastor, Javier Gómez‐Tabales, Hortensia Alonso‐Navarro, Ignacio Alvarez, Mariateresa Buongiorno, Maria de las Olas Cerezo‐Arias, Miquel Aguilar, José A. G. Agúndez, Félix Javier Jiménez‐Jiménez
Eur J Clin Invest. 2022 Nov; 52(11): e13847. Published online 2022 Aug 5. doi: 10.1111/eci.13847
PMCID:
PMC9787747
AbstractArticlePDF–255K
19.
PD-1 and LAG-3-positive T cells are associated with clinical outcomes of relapsed/refractory multiple myeloma patients
Ming Chen, Jinlian Zhu, Xuedong Yang, Jianxin Yao, Yuqing Liu, Qiang Liu
Eur J Med Res. 2022; 27: 296. Published online 2022 Dec 19. doi: 10.1186/s40001-022-00923-5
PMCID:
PMC9761990
AbstractArticlePDF–2.2M
20.
LAG3/CD4 Genes Variants and the Risk for Restless Legs Syndrome
Félix Javier Jiménez-Jiménez, Javier Gómez-Tabales, Hortensia Alonso-Navarro, Christopher Rodríguez, Laura Turpín-Fenoll, Jorge Millán-Pascual, Ignacio Álvarez, Pau Pastor, Marisol Calleja, Rafael García-Ruiz, Santiago Navarro-Muñoz, Marta Recio-Bermejo, José Francisco Plaza-Nieto, Esteban García-Albea, Elena García-Martín, José A. G. Agúndez
Int J Mol Sci. 2022 Dec; 23(23): 14795. Published online 2022 Nov 26. doi: 10.3390/ijms232314795
PMCID:
PMC9739762
AbstractArticlePDF–300K

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