PMC Links for GEO Profiles (Select 38065747) - PMC

Liviu Aron, Chenxi Qiu, Zhen Kai Ngian, Marianna Liang, Derek Drake, Jaejoon Choi, Marty A. Fernandez, Perle Roche, Emma L. Bunting, Ella K. Lacey, Sara E. Hamplova, Monlan Yuan, Michael S. Wolfe, David A. Bennett, Eunjung A. Lee, Bruce A. Yankner

Nat Commun. 2023; 14: 7030. Published online 2023 Nov 2. doi: 10.1038/s41467-023-42704-6

PMCID:: PMC10622455

Abstract Article PDF–3.5M

Select item 106051574.

REST Is Not Resting: REST/NRSF in Health and Disease

Lili Jin, Ying Liu, Yifan Wu, Yi Huang, Dianbao Zhang

Biomolecules. 2023 Oct; 13(10): 1477. Published online 2023 Oct 2. doi: 10.3390/biom13101477

PMCID:: PMC10605157

Abstract Article PDF–1.0M

Select item 105563985.

Genome-wide Association Studies of REST Gene Associated Neurological Diseases/traits with Related Single Nucleotide Polymorphisms

Jingjing Wang, Sagor Kumar Roy, Seidu A. Richard, Yuming Xu

Curr Neurovasc Res. 2023; 20(3): 410–422. Published online 2023. doi: 10.2174/1567202620666230727153306

PMCID:: PMC10556398

Abstract Article PDF–4.2M

Select item 104716936.

Repressor Element-1 Binding Transcription Factor (REST) as a Possible Epigenetic Regulator of Neurodegeneration and MicroRNA-Based Therapeutic Strategies

Ajmal Nassar, Sairaj Satarker, Prasada Chowdari Gurram, Dinesh Upadhya, SM Fayaz, Madhavan Nampoothiri

Mol Neurobiol. 2023; 60(10): 5557–5577. Published online 2023 Jun 16. doi: 10.1007/s12035-023-03437-1

PMCID:: PMC10471693

Abstract Article PDF–3.4M

Select item 103932287.

REST contributes to AKI-to-CKD transition through inducing ferroptosis in renal tubular epithelial cells

Shuiqin Gong, Aihong Zhang, Mengying Yao, Wang Xin, Xu Guan, Shaozong Qin, Yong Liu, Jiachuan Xiong, Ke Yang, Li Xiong, Ting He, Yinghui Huang, Jinghong Zhao

JCI Insight. 2023 Jun 8; 8(11): e166001. Published online 2023 Jun 8. doi: 10.1172/jci.insight.166001

PMCID:: PMC10393228

Abstract Article PDF–27M

Select item 102578538.

DNA methylation alterations at RE1-silencing transcription factor binding sites and their flanking regions in cancer

Ana Florencia Vega-Benedetti, Eleonora Loi, Loredana Moi, Patrizia Zavattari

Clin Epigenetics. 2023; 15: 98. Published online 2023 Jun 10. doi: 10.1186/s13148-023-01514-9

PMCID:: PMC10257853

Abstract Article PDF–7.0M

Select item 101766969.

CRISPR/Cas9-based genome-wide screening of the deubiquitinase subfamily identifies USP3 as a protein stabilizer of REST blocking neuronal differentiation and promotes neuroblastoma tumorigenesis

Janardhan Keshav Karapurkar, Min-Seong Kim, Jencia Carminha Colaco, Bharathi Suresh, Neha Sarodaya, Dong-Ho Kim, Chang-Hwan Park, Seok-Ho Hong, Kye-Seong Kim, Suresh Ramakrishna

J Exp Clin Cancer Res. 2023; 42: 121. Published online 2023 May 12. doi: 10.1186/s13046-023-02694-1

PMCID:: PMC10176696

Abstract Article PDF–11M

Select item 1005447810.

REST/NRSF Silencing Modifies Neuronal Gene Expression in siRNA-Treated HeLa Cells: A Preliminary Exploration in the Search for Neuronal Biomarkers of Cervical Cancer

Karen Cortés-Sarabia, Luz Del Carmen Alarcón-Romero, Miguel Ángel Mendoza-Catalán, Juan Carlos Carpio-Pedroza, Eduardo Castañeda-Saucedo, Carlos Ortuño-Pineda

Medicina (Kaunas) 2023 Mar; 59(3): 537. Published online 2023 Mar 9. doi: 10.3390/medicina59030537

PMCID:: PMC10054478

Abstract Article PDF–1.1M

Select item 955110111.

NRSF/REST lies at the intersection between epigenetic regulation, miRNA-mediated gene control and neurodevelopmental pathways associated with Intellectual disability (ID) and Schizophrenia

Mouhamed Alsaqati, Brittany A. Davis, Jamie Wood, Megan M. Jones, Lora Jones, Aishah Westwood, Olena Petter, Anthony R. Isles, David Linden, Marianne Van den Bree, Michael Owen, Jeremy Hall, Adrian J. Harwood

Transl Psychiatry. 2022; 12: 438. Published online 2022 Oct 10. doi: 10.1038/s41398-022-02199-z

PMCID:: PMC9551101

Abstract Article PDF–2.9M

Select item 937844712.

Deletion of RE1-silencing transcription factor in striatal astrocytes exacerbates manganese-induced neurotoxicity in mice

Edward Pajarillo, Mark Demayo, Alexis Digman, Ivan Nyarko-Danquah, Deok-Soo Son, Michael Aschner, Eunsook Lee

Glia. Author manuscript; available in PMC 2023 Oct 1.

Published in final edited form as: Glia. 2022 Oct; 70(10): 1886–1901. Published online 2022 May 31. doi: 10.1002/glia.24226

PMCID:: PMC9378447

Abstract Article PDF–1.6M

Select item 936044313.

Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner

Lucía García-Gutiérrez, Emma Fallahi, Nourhan Aboud, Niall Quinn, David Matallanas

Cell Death Dis. 2022 Aug; 13(8): 692. Published online 2022 Aug 8. doi: 10.1038/s41419-022-05147-3

PMCID:: PMC9360443

Abstract Article PDF–5.8M

Select item 915820014.

Plasma repressor element 1-silencing transcription factor levels are decreased in patients with Alzheimer's disease

Mingqing Wei, Jingnian Ni, Jing Shi, Ting Li, Xiaoqing Xu, Chenmeng Li, Bin Qin, Dongsheng Fan, Hengge Xie, Zhong Wang, Yongyan Wang, Tao Lu, Jinzhou Tian

BMC Geriatr. 2022; 22: 471. Published online 2022 Jun 1. doi: 10.1186/s12877-022-03163-8

PMCID:: PMC9158200

Abstract Article PDF–829K

Select item 906856615.

Significant decrease of a master regulator of genes (REST/NRSF) in high-grade squamous intraepithelial lesion and cervical cancer

Karen Cortés-Sarabia, Luz del Carmen Alarcón-Romero, Eugenia Flores-Alfaro, Berenice Illades-Aguiar, Amalia Vences-Velázquez, Miguel Ángel Mendoza-Catalán, Napoleón Navarro-Tito, Jesús Valdés, Ma Elena Moreno-Godínez, Carlos Ortuño-Pineda

Biomed J. 2021 Dec; 44(6 Suppl 2): S171–S178. Published online 2020 Aug 27. doi: 10.1016/j.bj.2020.08.012

PMCID:: PMC9068566

Abstract Article PDF–1.6M

Select item 893989216.

The transcriptional repressor REST drives lineage-stage-specific chromatin compaction at Ptch1 and AKT hyperactivation in medulloblastoma

Tara H.W. Dobson, Rong-Hua Tao, Jyothishmathi Swaminathan, Shinji Maegawa, Shavali Shaik, Javiera Bravo-Alegria, Ajay Sharma, Bridget Kennis, Yanwen Yang, Keri Callegari, Amanda R. Haltom, Pete Taylor, Mari Kogiso, Lin Qi, Soumen Khatua, Stewart Goldman, Rishi R. Lulla, Jason Fangusaro, Tobey J. MacDonald, Xiao-Nan Li, Cynthia Hawkins, Veena Rajaram, Vidya Gopalakrishnan

Sci Signal. Author manuscript; available in PMC 2022 Mar 22.

Published in final edited form as: Sci Signal. 2019 Jan 22; 12(565): eaan8680. Published online 2019 Jan 22. doi: 10.1126/scisignal.aan8680

PMCID:: PMC8939892

Abstract Article PDF–4.5M

Select item 869982417.

Reprogramming Human Adult Fibroblasts into GABAergic Interneurons

Andreas Bruzelius, Srisaiyini Kidnapillai, Janelle Drouin-Ouellet, Tom Stoker, Roger A. Barker, Daniella Rylander Ottosson

Cells. 2021 Dec; 10(12): 3450. Published online 2021 Dec 8. doi: 10.3390/cells10123450

PMCID:: PMC8699824

Abstract Article PDF–2.9M

Select item 863664818.

ALKBH5-mediated m⁶A demethylation of KCNK15-AS1 inhibits pancreatic cancer progression via regulating KCNK15 and PTEN/AKT signaling

Yuan He, HongQin Yue, Ying Cheng, Zhilong Ding, Zhen Xu, Chunyang Lv, Zheng Wang, Jing Wang, Chenglong Yin, Huihui Hao, Chuang Chen

Cell Death Dis. 2021 Dec; 12(12): 1121. Published online 2021 Dec 1. doi: 10.1038/s41419-021-04401-4

PMCID:: PMC8636648

Abstract Article PDF–4.3M

Select item 862658919.

Astrocytic transcription factor REST upregulates glutamate transporter EAAT2, protecting dopaminergic neurons from manganese-induced excitotoxicity

Edward Pajarillo, Alexis Digman, Ivan Nyarko-Danquah, Deok-Soo Son, Karam F.A. Soliman, Michael Aschner, Eunsook Lee

J Biol Chem. 2021 Dec; 297(6): 101372. Published online 2021 Oct 29. doi: 10.1016/j.jbc.2021.101372

PMCID:: PMC8626589

Abstract Article PDF–3.4M

Select item 861816720.

A Monoallelic Variant in REST Is Associated with Non-Syndromic Autosomal Dominant Hearing Impairment in a South African Family

Noluthando Manyisa, Isabelle Schrauwen, Leonardo Alves de Souza Rios, Shaheen Mowla, Cedrik Tekendo-Ngongang, Kalinka Popel, Kevin Esoh, Thashi Bharadwaj, Liz M. Nouel-Saied, Anushree Acharya, Abdul Nasir, Edmond Wonkam-Tingang, Carmen de Kock, Collet Dandara, Suzanne M. Leal, Ambroise Wonkam

Genes (Basel) 2021 Nov; 12(11): 1765. Published online 2021 Nov 6. doi: 10.3390/genes12111765

PMCID:: PMC8618167

Abstract Article PDF–8.4M

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