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Select item 110133861.

Single-molecule characterization of Sen1 translocation properties provides insights into eukaryotic factor-dependent transcription termination

Shuang Wang, Zhong Han, Terence R Strick

Nucleic Acids Res. 2024 Apr 12; 52(6): 3249–3261. Published online 2024 Jan 23. doi: 10.1093/nar/gkae026

PMCID:: PMC11013386

Abstract Article PDF–1.8M

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106476993.

A Protein–Protein Interaction Analysis Suggests a Wide Range of New Functions for the p21-Activated Kinase (PAK) Ste20

Ifeoluwapo Matthew Joshua, Meng Lin, Ariestia Mardjuki, Alessandra Mazzola, Thomas Höfken

Int J Mol Sci. 2023 Nov; 24(21): 15916. Published online 2023 Nov 2. doi: 10.3390/ijms242115916

PMCID:: PMC10647699

Abstract Article PDF–5.4M

Select item 105517004.

Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability

Prashant K. Mishra, Wei-Chun Au, Pedro G. Castineira, Nazrin Ali, John Stanton, Lars Boeckmann, Yoshimitsu Takahashi, Michael Costanzo, Charles Boone, Kerry S. Bloom, Peter H. Thorpe, Munira A. Basrai

Mol Biol Cell. 2023 Sep 1; 34(10): ar99. Published online 2023 Aug 17. doi: 10.1091/mbc.E23-03-0108

PMCID:: PMC10551700

Abstract Article PDF–3.7M

Select item 105166425.

ISW1a modulates cohesin distribution in centromeric and pericentromeric regions

Ireneusz Litwin, Małgorzata Nowicka, Katarzyna Markowska, Ewa Maciaszczyk-Dziubińska, Paulina Tomaszewska, Robert Wysocki, Karol Kramarz

Nucleic Acids Res. 2023 Sep 22; 51(17): 9101–9121. Published online 2023 Jul 24. doi: 10.1093/nar/gkad612

PMCID:: PMC10516642

Abstract Article PDF–2.8M

Select item 102922106.

Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin

Sanjeev Kumar Choudhry, Maxwell L. Neal, Song Li, Arti T. Navare, Trevor Van Eeuwen, Richard W. Wozniak, Fred D. Mast, Michael P. Rout, John D. Aitchison

J Cell Biol. 2023 Sep 4; 222(9): e202207060. Published online 2023 Jun 26. doi: 10.1083/jcb.202207060

PMCID:: PMC10292210

Abstract Article PDF–5.9M

Select item 102350867.

Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores

Ksenia Smurova, Michela Damizia, Carmela Irene, Stefania Stancari, Giovanna Berto, Giulia Perticari, Maria Giuseppina Iacovella, Ilaria D’Ambrosio, Maria Giubettini, Réginald Philippe, Chiara Baggio, Elisabetta Callegaro, Andrea Casagranda, Alessandro Corsini, Vincenzo Gentile Polese, Anna Ricci, Erik Dassi, Peter De Wulf

Nat Commun. 2023; 14: 3172. Published online 2023 Jun 1. doi: 10.1038/s41467-023-38920-9

PMCID:: PMC10235086

Abstract Article PDF–2.6M

Select item 92860238.

Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton

Curr Biol. 2022 Jul 11; 32(13): 2884–2896.e6. doi: 10.1016/j.cub.2022.05.019

PMCID:: PMC9286023

Abstract Article

Select item 92788589.

An integrated model for termination of RNA polymerase III transcription

Juanjuan Xie, Umberto Aiello, Yves Clement, Nouhou Haidara, Mathias Girbig, Jana Schmitzova, Vladimir Pena, Christoph W. Müller, Domenico Libri, Odil Porrua

Sci Adv. 2022 Jul; 8(28): eabm9875. Published online 2022 Jul 13. doi: 10.1126/sciadv.abm9875

PMCID:: PMC9278858

Abstract Article PDF–3.3M

Select item 920981110.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 886059811.

Modulated termination of non-coding transcription partakes in the regulation of gene expression

Nouhou Haidara, Marta Giannini, Odil Porrua

Nucleic Acids Res. 2022 Feb 22; 50(3): 1430–1448. Published online 2022 Jan 17. doi: 10.1093/nar/gkab1304

PMCID:: PMC8860598

Abstract Article PDF–3.4M

Select item 868278712.

Elongating RNA polymerase II and RNA:DNA hybrids hinder fork progression and gene expression at sites of head-on replication-transcription collisions

Luca Zardoni, Eleonora Nardini, Alessandra Brambati, Chiara Lucca, Ramveer Choudhary, Federica Loperfido, Simone Sabbioneda, Giordano Liberi

Nucleic Acids Res. 2021 Dec 16; 49(22): 12769–12784. Published online 2021 Dec 8. doi: 10.1093/nar/gkab1146

PMCID:: PMC8682787

Abstract Article PDF–8.6M

Select item 857106313.

Systems-level effects of allosteric perturbations to a model molecular switch

Tina Perica, Christopher J. P. Mathy, Jiewei Xu, Gwendolyn M. Jang, Yang Zhang, Robyn Kaake, Noah Ollikainen, Hannes Braberg, Danielle L. Swaney, David G. Lambright, Mark J. S. Kelly, Nevan J. Krogan, Tanja Kortemme

Nature. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Nature. 2021 Nov; 599(7883): 152–157. Published online 2021 Oct 13. doi: 10.1038/s41586-021-03982-6

PMCID:: PMC8571063

Abstract Article PDF–2.7M

Select item 851195014.

The histone chaperone Spt6 is required for normal recruitment of the capping enzyme Abd1 to transcribed regions

Rajaraman Gopalakrishnan, Fred Winston

J Biol Chem. 2021 Oct; 297(4): 101205. Published online 2021 Sep 17. doi: 10.1016/j.jbc.2021.101205

PMCID:: PMC8511950

Abstract Article PDF–3.1M

Select item 829842415.

Harmful R-loops are prevented via different cell cycle-specific mechanisms

Marta San Martin-Alonso, María E. Soler-Oliva, María García-Rubio, Tatiana García-Muse, Andrés Aguilera

Nat Commun. 2021; 12: 4451. Published online 2021 Jul 22. doi: 10.1038/s41467-021-24737-x

PMCID:: PMC8298424

Abstract Article PDF–2.2M

Select item 826305716.

Genetic and pharmacological evidence for kinetic competition between alternative poly(A) sites in yeast

Rachael Emily Turner, Paul F Harrison, Angavai Swaminathan, Calvin A Kraupner-Taylor, Belinda J Goldie, Michael See, Amanda L Peterson, Ralf B Schittenhelm, David R Powell, Darren J Creek, Bernhard Dichtl, Traude H Beilharz

eLife. 2021; 10: e65331. Published online 2021 Jul 7. doi: 10.7554/eLife.65331

PMCID:: PMC8263057

Abstract Article PDF–15M

Select item 809411717.

SUMOylation stabilizes sister kinetochore biorientation to allow timely anaphase

Xue Bessie Su, Menglu Wang, Claudia Schaffner, Olga O. Nerusheva, Dean Clift, Christos Spanos, David A. Kelly, Michael Tatham, Andreas Wallek, Yehui Wu, Juri Rappsilber, A. Arockia Jeyaprakash, Zuzana Storchova, Ronald T. Hay, Adèle L. Marston

J Cell Biol. 2021 Jul 5; 220(7): e202005130. Published online 2021 Apr 30. doi: 10.1083/jcb.202005130

PMCID:: PMC8094117

Abstract Article PDF–8.1M

Select item 809198118.

Essential histone chaperones collaborate to regulate transcription and chromatin integrity

Olga Viktorovskaya, James Chuang, Dhawal Jain, Natalia I. Reim, Francheska López-Rivera, Magdalena Murawska, Dan Spatt, L. Stirling Churchman, Peter J. Park, Fred Winston

Genes Dev. 2021 May 1; 35(9-10): 698–712. doi: 10.1101/gad.348431.121