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Items: 1 to 20 of 66

1.
MIG6 loss confers resistance to ALK/ROS1 inhibitors in NSCLC through EGFR activation by low-dose EGF
Nobuyuki Kondo, Takahiro Utsumi, Yuki Shimizu, Ai Takemoto, Tomoko Oh-hara, Ken Uchibori, Sophia Subat-Motoshi, Hironori Ninomiya, Kengo Takeuchi, Makoto Nishio, Yasunari Miyazaki, Ryohei Katayama
JCI Insight. 2023 Dec 22; 8(24): e173688. Published online 2023 Dec 22. doi: 10.1172/jci.insight.173688
PMCID:
PMC10807714
AbstractArticlePDF–3.4M
2.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
3.
Activity of the nonreceptor tyrosine kinase Ack1 is regulated by tyrosine phosphorylation of its Mig6 homology region
Yağmur Kan, W. Todd Miller
FEBS Lett. Author manuscript; available in PMC 2023 Jan 26.
Published in final edited form as: FEBS Lett. 2022 Nov; 596(21): 2808–2820. Published online 2022 Oct 5. doi: 10.1002/1873-3468.14505
PMCID:
PMC9879303
AbstractArticlePDF–1.1M
4.
MIG-6 Is Critical for Progesterone Responsiveness in Human Complex Atypical Hyperplasia and Early-Stage Endometrial Cancer
Olivia Jeong, Russell R. Broaddus, Bruce A. Lessey, John I. Risinger, Mark I. Hunter, Tae Hoon Kim
Int J Mol Sci. 2022 Dec; 23(23): 14596. Published online 2022 Nov 23. doi: 10.3390/ijms232314596
PMCID:
PMC9738720
AbstractArticlePDF–7.6M
5.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M
6.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
7.
A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity
Danielle L. Swaney, Dana J. Ramms, Zhiyong Wang, Jisoo Park, Yusuke Goto, Margaret Soucheray, Neil Bhola, Kyumin Kim, Fan Zheng, Yan Zeng, Michael McGregor, Kari A. Herrington, Rachel O’Keefe, Nan Jin, Nathan K. VanLandingham, Helene Foussard, John Von Dollen, Mehdi Bouhaddou, David Jimenez-Morales, Kirsten Obernier, Jason F. Kreisberg, Minkyu Kim, Daniel E. Johnson, Natalia Jura, Jennifer R. Grandis, J. Silvio Gutkind, Trey Ideker, Nevan J. Krogan
Science. Author manuscript; available in PMC 2022 Apr 13.
Published in final edited form as: Science. 2021 Oct; 374(6563): eabf2911. Published online 2021 Oct 1. doi: 10.1126/science.abf2911
PMCID:
PMC9005332
AbstractArticlePDF–2.0M
8.
Mig‐6 could inhibit cell proliferation and induce apoptosis in esophageal squamous cell carcinoma
Yuantao Cui, Ying Kang, Peng Zhang, Yuanguo Wang, Zhaoyu Yang, Chao Lu, Peng Zhang
Thorac Cancer. 2022 Jan; 13(1): 54–60. Published online 2021 Nov 30. doi: 10.1111/1759-7714.14223
PMCID:
PMC8720621
AbstractArticlePDF–1.3M
9.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
10.
MicroRNA-374a Promotes Hepatocellular Carcinoma Cell Proliferation by Targeting Mitogen-Inducible Gene 6 (MIG-6)
Hui Li, Huicheng Chen, Haibin Wang, Yilong Dong, Min Yin, Liang Zhang, Jia Wei
Oncol Res. 2018; 26(4): 557–563. Published online 2018 May 7. doi: 10.3727/096504017X15000784459799
PMCID:
PMC7844684
AbstractArticlePDF–2.8M
11.
Differential Glucocorticoid-Dependent Regulation and Function of the ERRFI1 Gene in Triple-Negative Breast Cancer
Chromewell Agustin R Mojica, Weand S Ybañez, Kevin Christian V Olarte, Alyssa Beatrice C Poblete, Pia D Bagamasbad
Endocrinology. 2020 Jul; 161(7): bqaa082. Published online 2020 May 20. doi: 10.1210/endocr/bqaa082
PMCID:
PMC7316368
AbstractArticle
12.
Suppression of Mig-6 overcomes the acquired EGFR-TKI resistance of lung adenocarcinoma
Da Hyun Kang, Sung Soo Jung, Min-Kyung Yeo, Da Hye Lee, Geon Yoo, Sang Yeon Cho, In-Jae Oh, Ju-Ock Kim, Hee Sun Park, Chaeuk Chung, Jeong Eun Lee
BMC Cancer. 2020; 20: 571. Published online 2020 Jun 18. doi: 10.1186/s12885-020-07057-z
PMCID:
PMC7302243
AbstractArticlePDF–4.3M
13.
Altered Expression of Three EGFR Posttranslational Regulators MDGI, MIG6, and EIG121 in Invasive Breast Carcinomas
Didier Meseure, Kinan Drak Alsibai, Sophie Vacher, Rana Hatem, Andre Nicolas, Celine Callens, Florence Lerebours, Ivan Bieche
Anal Cell Pathol (Amst) 2020; 2020: 9268236. Published online 2020 Apr 20. doi: 10.1155/2020/9268236
PMCID:
PMC7189325
AbstractArticlePDF–1.8M
14.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
15.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9
PMCID:
PMC6981206
AbstractArticlePDF–3.7M
16.
An integrated analysis of public genomic data unveils a possible functional mechanism of psoriasis risk via a long-range ERRFI1 enhancer
Naoto Kubota, Mikita Suyama
BMC Med Genomics. 2020; 13: 8. Published online 2020 Jan 22. doi: 10.1186/s12920-020-0662-9
PMCID:
PMC6977261
AbstractArticlePDF–1.9M
17.
The metastasis suppressor NDRG1 down-regulates the epidermal growth factor receptor via a lysosomal mechanism by up-regulating mitogen-inducible gene 6
Sharleen V. Menezes, Zaklina Kovacevic, Des R. Richardson
J Biol Chem. 2019 Mar 15; 294(11): 4045–4064. Published online 2019 Jan 24. doi: 10.1074/jbc.RA118.006279
Correction in:
J Biol Chem. 2019 Aug 2; 294(31): 11675.
PMCID:
PMC6422098
AbstractArticlePDF–6.9M
18.
miR‐205 mediates adaptive resistance to MET inhibition via ERRFI1 targeting and raised EGFR signaling
Cristina Migliore, Elena Morando, Elena Ghiso, Sergio Anastasi, Vera P Leoni, Maria Apicella, Davide Cora', Anna Sapino, Filippo Pietrantonio, Filippo De Braud, Amedeo Columbano, Oreste Segatto, Silvia Giordano
EMBO Mol Med. 2018 Sep; 10(9): e8746. Published online 2018 Jul 24. doi: 10.15252/emmm.201708746
PMCID:
PMC6127885
AbstractArticlePDF–1.0M
19.
MIG-6 suppresses endometrial epithelial cell proliferation by inhibiting phospho-AKT
Jung-Yoon Yoo, Hee-Bum Kang, Russell R. Broaddus, John I. Risinger, Kyung-Chul Choi, Tae Hoon Kim
BMC Cancer. 2018; 18: 605. Published online 2018 May 29. doi: 10.1186/s12885-018-4502-7
PMCID:
PMC5975686
AbstractArticlePDF–1.9M
20.
Differential roles of ERRFI1 in EGFR and AKT pathway regulation affect cancer proliferation
Junmei Cairns, Brooke L Fridley, Gregory D Jenkins, Yongxian Zhuang, Jia Yu, Liewei Wang
EMBO Rep. 2018 Mar; 19(3): e44767. Published online 2018 Jan 15. doi: 10.15252/embr.201744767
PMCID:
PMC5835844
AbstractArticlePDF–7.2M

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