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Items: 1 to 20 of 62

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Neutrophil responsiveness to IL-10 impairs clearance of Streptococcus pneumoniae from the lungs
Kadi J Horn, Sam Fulte, Michael Yang, Brian P Lorenz, Sarah E Clark
J Leukoc Biol. 2024 Jan; 115(1): 4–15. Published online 2023 Jun 29. doi: 10.1093/jleuko/qiad070
PMCID:
PMC10768920
AbstractArticlePDF–4.7M
3.
The IL-10 receptor inhibits cell extrinsic signals necessary for STAT1-dependent macrophage accumulation during colitis
Izabel Patik, Naresh S. Redhu, Alal Eran, Bin Bao, Anubhab Nandy, Ying Tang, Shorouk El Sayed, Zeli Shen, Jonathan Glickman, James G. Fox, Scott B. Snapper, Bruce H. Horwitz
Mucosal Immunol. Author manuscript; available in PMC 2023 Aug 16.
Published in final edited form as: Mucosal Immunol. 2023 Jun; 16(3): 233–249. Published online 2023 Mar 2. doi: 10.1016/j.mucimm.2023.02.006
PMCID:
PMC10431098
AbstractArticlePDF–2.3M
4.
CCR2 promotes monocyte recruitment and intestinal inflammation in mice lacking the interleukin-10 receptor
Shorouk El Sayed, Izabel Patik, Naresh S. Redhu, Jonathan N. Glickman, Konstantinos Karagiannis, El Sayed Y. El Naenaeey, Gamal A. Elmowalid, Ashraf M. Abd El Wahab, Scott B. Snapper, Bruce H. Horwitz
Sci Rep. 2022; 12: 452. Published online 2022 Jan 10. doi: 10.1038/s41598-021-04098-7
PMCID:
PMC8748948
AbstractArticlePDF–3.5M
5.
Interleukin-10 improves stroke outcome by controlling the detrimental Interleukin-17A response
Marius Piepke, Bettina H. Clausen, Peter Ludewig, Jonas H. Vienhues, Tanja Bedke, Ehsan Javidi, Björn Rissiek, Larissa Jank, Leonie Brockmann, Inga Sandrock, Karoline Degenhardt, Alina Jander, Vanessa Roth, Ines S. Schädlich, Immo Prinz, Richard A. Flavell, Yasushi Kobayashi, Thomas Renné, Christian Gerloff, Samuel Huber, Tim Magnus, Mathias Gelderblom
J Neuroinflammation. 2021; 18: 265. Published online 2021 Nov 13. doi: 10.1186/s12974-021-02316-7
PMCID:
PMC8590298
AbstractArticlePDF–4.2M
6.
Intestinal barrier dysfunction plays an integral role in arthritis pathology and can be targeted to ameliorate disease
Diana E. Matei, Madhvi Menon, Dagmar G. Alber, Andrew M. Smith, Bahman Nedjat-Shokouhi, Alessio Fasano, Laura Magill, Amanda Duhlin, Samuel Bitoun, Aude Gleizes, Salima Hacein-Bey-Abina, Jessica J. Manson, Elizabeth C. Rosser, The ABIRISK Consortium, Nigel Klein, Paul A. Blair, Claudia Mauri
Med (N Y) 2021 Jul 9; 2(7): 864–883.e9. doi: 10.1016/j.medj.2021.04.013
PMCID:
PMC8280953
AbstractArticle
7.
Cytokine receptor clustering in sensory neurons with an engineered cytokine fusion protein triggers unique pain resolution pathways
Judith Prado, Remco H. S. Westerink, Jelena Popov-Celeketic, Cristine Steen-Louws, Aridaman Pandit, Sabine Versteeg, Wouter van de Worp, Deon H. A. J. Kanters, Kris A. Reedquist, Leo Koenderman, C. Erik Hack, Niels Eijkelkamp
Proc Natl Acad Sci U S A. 2021 Mar 16; 118(11): e2009647118. Published online 2021 Mar 8. doi: 10.1073/pnas.2009647118
PMCID:
PMC7980471
AbstractArticlePDF–2.0M
8.
CD4+ follicular regulatory T cells optimize the influenza virus–specific B cell response
Yisi Lu, Roy Jiang, Alec W. Freyn, Jiawei Wang, Shirin Strohmeier, Katlyn Lederer, Michela Locci, Hongyu Zhao, Davide Angeletti, Kevin C. O’Connor, Steven H. Kleinstein, Raffael Nachbagauer, Joe Craft
J Exp Med. 2021 Mar 1; 218(3): e20200547. Published online 2020 Dec 16. doi: 10.1084/jem.20200547
PMCID:
PMC7748821
AbstractArticlePDF–4.6M
9.
Blimp-1 is essential for allergen-induced asthma and Th2 cell development in the lung
Kun He, Angela Hettinga, Sagar Laxman Kale, Sanmei Hu, Markus M. Xie, Alexander L. Dent, Anuradha Ray, Amanda C. Poholek
J Exp Med. 2020 Jul 6; 217(7): e20190742. Published online 2020 May 12. doi: 10.1084/jem.20190742
PMCID:
PMC7336314
AbstractArticlePDF–5.6M
10.
T follicular regulatory cells and IL-10 promote food antigen–specific IgE
Markus M. Xie, Qiang Chen, Hong Liu, Kai Yang, Byunghee Koh, Hao Wu, Soheila J. Maleki, Barry K. Hurlburt, Joan Cook-Mills, Mark H. Kaplan, Alexander L. Dent
J Clin Invest. 2020 Jul 1; 130(7): 3820–3832. Published online 2020 Jun 8. doi: 10.1172/JCI132249
PMCID:
PMC7324176
AbstractArticlePDF–5.4M
11.
Aryl Hydrocarbon Receptor Contributes to the Transcriptional Program of IL-10-Producing Regulatory B Cells
Christopher J.M. Piper, Elizabeth C. Rosser, Kristine Oleinika, Kiran Nistala, Thomas Krausgruber, André F. Rendeiro, Aggelos Banos, Ignat Drozdov, Matteo Villa, Scott Thomson, Georgina Xanthou, Christoph Bock, Brigitta Stockinger, Claudia Mauri
Cell Rep. 2019 Nov 12; 29(7): 1878–1892.e7. Published online 2019 Nov 12. doi: 10.1016/j.celrep.2019.10.018
PMCID:
PMC6856759
AbstractArticle
12.
Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes
Prashant Rajbhandari, Douglas Arneson, Sydney K Hart, In Sook Ahn, Graciel Diamante, Luis C Santos, Nima Zaghari, An-Chieh Feng, Brandon J Thomas, Laurent Vergnes, Stephen D Lee, Abha K Rajbhandari, Karen Reue, Stephen T Smale, Xia Yang, Peter Tontonoz
eLife. 2019; 8: e49501. Published online 2019 Oct 23. doi: 10.7554/eLife.49501
PMCID:
PMC6837845
AbstractArticlePDF–4.8M
13.
NK Cell IL-10 Production Requires IL-15 and IL-10 Driven STAT3 Activation
Sarah E. Clark, Kristina S. Burrack, Stephen C. Jameson, Sara E. Hamilton, Laurel L. Lenz
Front Immunol. 2019; 10: 2087. Published online 2019 Sep 4. doi: 10.3389/fimmu.2019.02087
PMCID:
PMC6736993
AbstractArticlePDF–3.7M
14.
IL-10-Dependent Crosstalk between Murine Marginal Zone B Cells, Macrophages, and CD8α+ Dendritic Cells Promotes Listeria monocytogenes Infection
Dong Liu, Xiangyun Yin, Sam J. Olyha, Manuela Sales L. Nascimento, Pei Chen, Theresa White, Uthaman Gowthaman, Tingting Zhang, Jake A. Gertie, Biyan Zhang, Lan Xu, Marina Yurieva, Lesley Devine, Adam Williams, Stephanie C. Eisenbarth
Immunity. Author manuscript; available in PMC 2020 Jul 16.
Published in final edited form as: Immunity. 2019 Jul 16; 51(1): 64–76.e7. Published online 2019 Jun 20. doi: 10.1016/j.immuni.2019.05.011
PMCID:
PMC6685086
AbstractArticlePDF–2.3M
15.
Blocking IL-10 receptor signaling ameliorates Mycobacterium tuberculosis infection during influenza-induced exacerbation
Sarah Ring, Lars Eggers, Jochen Behrends, Adam Wutkowski, Dominik Schwudke, Andrea Kröger, Alexandra Maximiliane Hierweger, Christoph Hölscher, Gülsah Gabriel, Bianca E. Schneider
JCI Insight. 2019 May 16; 4(10): e126533. Published online 2019 May 16. doi: 10.1172/jci.insight.126533
PMCID:
PMC6542649
AbstractArticlePDF–3.6M
16.
Critical role for the microbiota in CX3CR1+ intestinal mononuclear phagocyte regulation of intestinal T cell responses
Myunghoo Kim, Carolina Galan, Andrea A. Hill, Wan-Jung Wu, Hannah Fehlner-Peach, Hyo Won Song, Deborah Schady, Matthew L. Bettini, Kenneth W. Simpson, Randy S. Longman, Dan R. Littman, Gretchen E. Diehl
Immunity. Author manuscript; available in PMC 2019 Jul 17.
Published in final edited form as: Immunity. 2018 Jul 17; 49(1): 151–163.e5. Published online 2018 Jul 3. doi: 10.1016/j.immuni.2018.05.009
PMCID:
PMC6051886
AbstractArticlePDF–1.2M
17.
IL-10 Receptor Signaling Empowers Regulatory T Cells to Control Th17 Responses and Protect from GN
Paul Diefenhardt, Anna Nosko, Malte A. Kluger, Johannes V. Richter, Claudia Wegscheid, Yasushi Kobayashi, Gisa Tiegs, Samuel Huber, Richard A. Flavell, Rolf A.K. Stahl, Oliver M. Steinmetz
J Am Soc Nephrol. 2018 Jul; 29(7): 1825–1837. Published online 2018 Jun 4. doi: 10.1681/ASN.2017091044
PMCID:
PMC6050938
AbstractArticle
18.
Induction of Nitric-Oxide Metabolism in Enterocytes Alleviates Colitis and Inflammation-Associated Colon Cancer
Noa Stettner, Chava Rosen, Biana Bernshtein, Shiri Gur-Cohen, Julia Frug, Alon Silberman, Alona Sarver, Narin N. Carmel-Neiderman, Raya Eilam, Inbal Biton, Meirav Pevsner-Fischer, Niv Zmora, Alexander Brandis, Keren Bahar Halpern, Ram Mazkereth, Diego di Bernardo, Nicola Brunetti-Pierri, Muralidhar H. Premkumar, Gillian Dank, Sandesh C.S. Nagamani, Steffen Jung, Alon Harmelin, Ayelet Erez
Cell Rep. 2018 May 15; 23(7): 1962–1976. Published online 2018 May 15. doi: 10.1016/j.celrep.2018.04.053
PMCID:
PMC5976577
AbstractArticle
19.
Interleukin-10 from CD4+ follicular regulatory T cells promotes the germinal center response
Brian J. Laidlaw, Yisi Lu, Robert A. Amezquita, Jason S. Weinstein, Jason A. Vander Heiden, Namita T. Gupta, Steven H. Kleinstein, Susan M. Kaech, Joe Craft
Sci Immunol. Author manuscript; available in PMC 2018 Oct 20.
Published in final edited form as: Sci Immunol. 2017 Oct 20; 2(16): eaan4767. doi: 10.1126/sciimmunol.aan4767
PMCID:
PMC5846620
AbstractArticlePDF–1.6M
20.
CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells
K. Oleinika, E. C. Rosser, D. E. Matei, K. Nistala, A. Bosma, I. Drozdov, C. Mauri
Nat Commun. 2018; 9: 684. Published online 2018 Feb 15. doi: 10.1038/s41467-018-02911-y
PMCID:
PMC5814456
AbstractArticlePDF–2.3M

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