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Select item 109546571.

METTL3-dependent m⁶A modification of PSEN1 mRNA regulates craniofacial development through the Wnt/β-catenin signaling pathway

Lan Ma, Xi Zhou, Siyue Yao, Xinyu Zhang, Ji Mao, Barbara Vona, Liwen Fan, Shu Lou, Dandan Li, Lin Wang, Yongchu Pan

Cell Death Dis. 2024 Mar; 15(3): 229. Published online 2024 Mar 20. doi: 10.1038/s41419-024-06606-9

PMCID:: PMC10954657

Article PDF–6.6M

Select item 108907302.

Differential allelic representation (DAR) identifies candidate eQTLs and improves transcriptome analysis

Lachlan Baer, Karissa Barthelson, John H. Postlethwait, David L. Adelson, Stephen M. Pederson, Michael Lardelli

PLoS Comput Biol. 2024 Feb; 20(2): e1011868. Published online 2024 Feb 12. doi: 10.1371/journal.pcbi.1011868

PMCID:: PMC10890730

Article PDF–2.4M

Select item 106341203.

Repeated sleep deprivation decreases the flux into hexosamine biosynthetic pathway/O-GlcNAc cycling and aggravates Alzheimer’s disease neuropathology in adult zebrafish

Jiwon Park, Dong Yeol Kim, Geum-Sook Hwang, Inn-Oc Han

J Neuroinflammation. 2023; 20: 257. Published online 2023 Nov 9. doi: 10.1186/s12974-023-02944-1

PMCID:: PMC10634120

Article PDF–13M

Select item 99133254.

Unraveling Presenilin 2 Functions in a Knockout Zebrafish Line to Shed Light into Alzheimer’s Disease Pathogenesis

Lucia Barazzuol, Domenico Cieri, Nicola Facchinello, Tito Calì, Philip Washbourne, Francesco Argenton, Paola Pizzo

Cells. 2023 Feb; 12(3): 376. Published online 2023 Jan 19. doi: 10.3390/cells12030376

PMCID:: PMC9913325

Article PDF–2.9M

Select item 86042725.

Accelerated loss of hypoxia response in zebrafish with familial Alzheimer’s disease-like mutation of presenilin 1

Morgan Newman, Hani Moussavi Nik, Greg T Sutherland, Nhi Hin, Woojin S Kim, Glenda M Halliday, Suman Jayadev, Carole Smith, Angela S Laird, Caitlin W Lucas, Thaksaon Kittipassorn, Dan J Peet, Michael Lardelli

Hum Mol Genet. 2020 Jul 15; 29(14): 2379–2394. Published online 2020 Jun 26. doi: 10.1093/hmg/ddaa119

PMCID:: PMC8604272

Article PDF–1.1M

Select item 82033226.

Zebrafish Chromosome 14 Gene Differential Expression in the fmr1^hu2787 Model of Fragile X Syndrome

Karissa Barthelson, Lachlan Baer, Yang Dong, Melanie Hand, Zac Pujic, Morgan Newman, Geoffrey J. Goodhill, Robert I. Richards, Stephen M. Pederson, Michael Lardelli

Front Genet. 2021; 12: 625466. Published online 2021 May 31. doi: 10.3389/fgene.2021.625466

PMCID:: PMC8203322

Article PDF–1.2M

Select item 79923527.

Transcriptome analyses of 7-day-old zebrafish larvae possessing a familial Alzheimer’s disease-like mutation in psen1 indicate effects on oxidative phosphorylation, ECM and MCM functions, and iron homeostasis

Yang Dong, Morgan Newman, Stephen M. Pederson, Karissa Barthelson, Nhi Hin, Michael Lardelli

BMC Genomics. 2021; 22: 211. Published online 2021 Mar 24. doi: 10.1186/s12864-021-07509-1

PMCID:: PMC7992352

Article PDF–2.6M

Select item 78312468.

No observed effect on brain vasculature of Alzheimer’s disease-related mutations in the zebrafish presenilin 1 gene

Karissa Barthelson, Morgan Newman, Cameron J. Nowell, Michael Lardelli

Mol Brain. 2021; 14: 22. Published online 2021 Jan 25. doi: 10.1186/s13041-021-00734-5

PMCID:: PMC7831246

Article PDF–1.4M

Select item 69803989.

Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2

Nhi Hin, Morgan Newman, Jan Kaslin, Alon M. Douek, Amanda Lumsden, Seyed Hani Moussavi Nik, Yang Dong, Xin-Fu Zhou, Noralyn B. Mañucat-Tan, Alastair Ludington, David L. Adelson, Stephen Pederson, Michael Lardelli

PLoS One. 2020; 15(1): e0227258. Published online 2020 Jan 24. doi: 10.1371/journal.pone.0227258

PMCID:: PMC6980398

Article PDF–4.7M

Select item 686381110.

High-fat diet impairs cognitive function of zebrafish

Shinichi Meguro, Sayaka Hosoi, Takahiro Hasumura

Sci Rep. 2019; 9: 17063. Published online 2019 Nov 19. doi: 10.1038/s41598-019-53634-z

PMCID:: PMC6863811

Article PDF–1.4M

Select item 661873111.

Presenilin1 Regulates Histamine Neuron Development and Behavior in Zebrafish, Danio rerio

Maria Sundvik, Yu-Chia Chen, Pertti Panula

J Neurosci. 2013 Jan 23; 33(4): 1589–1597. doi: 10.1523/JNEUROSCI.1802-12.2013

PMCID:: PMC6618731

Article PDF–2.5M

Select item 650001712.

Brain transcriptome analysis of a familial Alzheimer’s disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production

Morgan Newman, Nhi Hin, Stephen Pederson, Michael Lardelli

Mol Brain. 2019; 12: 43. Published online 2019 May 3. doi: 10.1186/s13041-019-0467-y

PMCID:: PMC6500017

Article PDF–548K

Select item 632053813.

Bax inhibitor 1 is a γ-secretase–independent presenilin-binding protein

Shenjie Wu, Wenqi Song, Catherine C. L. Wong, Yigong Shi

Proc Natl Acad Sci U S A. 2019 Jan 2; 116(1): 141–147. Published online 2018 Dec 17. doi: 10.1073/pnas.1810870116

PMCID:: PMC6320538

Article PDF–1.8M

Select item 571220914.

Transcriptomic profiling of mTOR and ryanodine receptor signaling molecules in developing zebrafish in the absence and presence of PCB 95

Daniel F. Frank, Galen W. Miller, Richard E. Connon, Juergen Geist, Pamela J. Lein

PeerJ. 2017; 5: e4106. Published online 2017 Nov 29. doi: 10.7717/peerj.4106

PMCID:: PMC5712209

Article PDF–5.2M

Select item 549757515.

Role of Dll4 / Notch in the formation and wiring of the lymphatic network in zebrafish

Ilse Geudens, Robert Herpers, Karlien Hermans, Inmaculada Segura, Carmen Ruiz de Almodovar, Jeroen Bussmann, Frederik De Smet, Wouter Vandevelde, Benjamin M Hogan, Arndt Siekmann, Filip Claes, John C Moore, Anna Silvia Pistocchi, Sonja Loges, Massimiliano Mazzone, Giovanni Mariggi, Françoise Bruyère, Franco Cotelli, Dontscho Kerjaschki, Agnes Noël, Jean-Michel Foidart, Holger Gerhardt, Annelii Ny, Tobias Langenberg, Nathan D Lawson, Henricus J Duckers, Stefan Schulte-Merker, Peter Carmeliet, Mieke Dewerchin

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Jul 5.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2010 Sep; 30(9): 1695–1702. Published online 2010 May 13. doi: 10.1161/ATVBAHA.110.203034

PMCID:: PMC5497575

Article PDF–1.2M

Select item 547959116.

Mitochondrion to endoplasmic reticulum apposition length in zebrafish embryo spinal progenitors is unchanged in response to perturbations associated with Alzheimer’s disease

Morgan Newman, Lena Halter, Anne Lim, Michael Lardelli

PLoS One. 2017; 12(6): e0179859. Published online 2017 Jun 21. doi: 10.1371/journal.pone.0179859

PMCID:: PMC5479591

Article PDF–17M

Select item 533797417.

Evolution of complexity in the zebrafish synapse proteome

Àlex Bayés, Mark O. Collins, Rita Reig-Viader, Gemma Gou, David Goulding, Abril Izquierdo, Jyoti S. Choudhary, Richard D. Emes, Seth G. N. Grant

Nat Commun. 2017; 8: 14613. Published online 2017 Mar 2. doi: 10.1038/ncomms14613

PMCID:: PMC5337974

Article PDF–2.0M

Select item 463413718.

RFX transcription factors are essential for hearing in mice

Ran Elkon, Beatrice Milon, Laura Morrison, Manan Shah, Sarath Vijayakumar, Manoj Racherla, Carmen C. Leitch, Lorna Silipino, Shadan Hadi, Michèle Weiss-Gayet, Emmanuèle Barras, Christoph D. Schmid, Aouatef Ait-Lounis, Ashley Barnes, Yang Song, David J. Eisenman, Efrat Eliyahu, Gregory I. Frolenkov, Scott E. Strome, Bénédicte Durand, Norann A. Zaghloul, Sherri M. Jones, Walter Reith, Ronna Hertzano

Nat Commun. 2015; 6: 8549. Published online 2015 Oct 15. doi: 10.1038/ncomms9549

PMCID:: PMC4634137

Article PDF–5.5M

Select item 440680419.

The Cardiac Transcriptome and Dilated Cardiomyopathy Genes in Zebrafish

Yu-Huan Shih, Yuji Zhang, Yonghe Ding, Christian A. Ross, Hu Li, Timothy M. Olson, Xiaolei Xu

Circ Cardiovasc Genet. Author manuscript; available in PMC 2016 Apr 1.

Published in final edited form as: Circ Cardiovasc Genet. 2015 Apr; 8(2): 261–269. Published online 2015 Jan 11. doi: 10.1161/CIRCGENETICS.114.000702

PMCID:: PMC4406804

Article PDF–532K

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Article PDF–1.0M

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