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Select item 111637741.

Genome-wide DNA methylation in relation to ARID1A deficiency in ovarian clear cell carcinoma

Shang Li, Gert Jan Meersma, Jolanta Kupryjanczyk, Steven de Jong, G. Bea A. Wisman

J Transl Med. 2024; 22: 556. Published online 2024 Jun 10. doi: 10.1186/s12967-024-05311-7

PMCID:: PMC11163774

Abstract Article PDF–4.6M

Select item 111628082.

ARID1A regulates DNA repair through chromatin organization and its deficiency triggers DNA damage-mediated anti-tumor immune response

Ali Bakr, Giuditta Della Corte, Olivera Veselinov, Simge Kelekçi, Mei-Ju May Chen, Yu-Yu Lin, Gianluca Sigismondo, Marika Iacovone, Alice Cross, Rabail Syed, Yunhee Jeong, Etienne Sollier, Chun- Shan Liu, Pavlo Lutsik, Jeroen Krijgsveld, Dieter Weichenhan, Christoph Plass, Odilia Popanda, Peter Schmezer

Nucleic Acids Res. 2024 Jun 10; 52(10): 5698–5719. Published online 2024 Apr 8. doi: 10.1093/nar/gkae233

PMCID:: PMC11162808

Abstract Article PDF–7.7M

Select item 111481843.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 110075444.

Deep‐targeted gene sequencing reveals ARID1A mutation as an important driver of glioblastoma

Menglin Xiao, Xiaoteng Cui, Can Xu, Lei Xin, Jixing Zhao, Shixue Yang, Biao Hong, Yanli Tan, Jie Zhang, Xiang Li, Jie Li, Chunsheng Kang, Chuan Fang

CNS Neurosci Ther. 2024 Apr; 30(4): e14698. Published online 2024 Apr 11. doi: 10.1111/cns.14698

PMCID:: PMC11007544

Abstract Article PDF–13M

Select item 109421085.

Increased genomic instability and reshaping of tissue microenvironment underlie oncogenic properties of Arid1a mutations

Alessandro D’Ambrosio, Davide Bressan, Elisa Ferracci, Francesco Carbone, Patrizia Mulè, Federico Rossi, Caterina Barbieri, Elisa Sorrenti, Gaia Fiaccadori, Thomas Detone, Elena Vezzoli, Salvatore Bianchi, Chiara Sartori, Simona Corso, Akihisa Fukuda, Giovanni Bertalot, Andrea Falqui, Mattia Barbareschi, Alessandro Romanel, Diego Pasini, Fulvio Chiacchiera

Sci Adv. 2024 Mar 15; 10(11): eadh4435. Published online 2024 Mar 15. doi: 10.1126/sciadv.adh4435

PMCID:: PMC10942108

Abstract Article PDF–9.8M

Select item 109332676.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 109230317.

Treatments, prognostic factors, and genetic heterogeneity in advanced cholangiocarcinoma: A multicenter real‐world study

Alessandro Ottaiano, Mariachiara Santorsola, Anna Diana, Andrea Belli, Maria Luisa Lentini Graziano, Jessica Orefice, Renato Patrone, Annabella Di Mauro, Giosuè Scognamiglio, Fabiana Tatangelo, Mario De Bellis, Mauro Piccirillo, Francesco Fiore, Salvatore Stilo, Luca Tarotto, Marco Correra, Sara Di Lorenzo, Maurizio Capuozzo, Antonio Avallone, Lucrezia Silvestro, Antonella Bianco, Vincenza Granata, Piera Federico, Vincenzo Montesarchio, Bruno Daniele, Francesco Izzo, Guglielmo Nasti

Cancer Med. 2024 Feb; 13(4): e6892. Published online 2024 Mar 8. doi: 10.1002/cam4.6892

PMCID:: PMC10923031

Abstract Article PDF–904K

Select item 108687658.

ARID1A loss is associated with increased NRF2 signaling in human head and neck squamous cell carcinomas

Vinh Nguyen, Travis P. Schrank, Michael B. Major, Bernard E. Weissman

PLoS One. 2024; 19(2): e0297741. Published online 2024 Feb 15. doi: 10.1371/journal.pone.0297741

PMCID:: PMC10868765

Abstract Article PDF–2.3M

Select item 108596159.

ARID1A loss induces P4HB to activate fibroblasts to support lung cancer cell growth, invasion, and chemoresistance

Risheng Huang, Danni Wu, Kangliang Zhang, Guanqiong Hu, Yu Liu, Yi Jiang, Chichao Wang, Yuanliang Zheng

Cancer Sci. 2024 Feb; 115(2): 439–451. Published online 2023 Dec 15. doi: 10.1111/cas.16052

PMCID:: PMC10859615

Abstract Article PDF–4.5M

Select item 1081512810.

The Role of the AT-Rich Interaction Domain 1A Gene (ARID1A) in Human Carcinogenesis

Jing Jing Li, Cheok Soon Lee

Genes (Basel) 2024 Jan; 15(1): 5. Published online 2023 Dec 19. doi: 10.3390/genes15010005

PMCID:: PMC10815128

Abstract Article PDF–2.8M

Select item 1078754211.

Chromatin accessibility complex subunit 1 enhances tumor growth by regulating the oncogenic transcription of YAP in breast and cervical cancer

Shasha Li, Lulu Wang, Jing Shi, Yi Chen, Ang Xiao, Bingyue Huo, Wenjing Tian, Shilu Zhang, Gang Yang, Wensheng Gong, Huixia Zhang

PeerJ. 2024; 12: e16752. Published online 2024 Jan 10. doi: 10.7717/peerj.16752

PMCID:: PMC10787542

Abstract Article PDF–13M

Select item 1075965912.

ARID1A deficiency promotes progression and potentiates therapeutic antitumour immunity in hepatitis B virus-related hepatocellular carcinoma

Tao Xing, Li Li, Xiaosong Rao, Jing Zhao, Yiran Chen, Gaoda Ju, Yaping Xu, Xuan Gao, Guilan Dong, Xuefeng Xia, Yanfang Guan, Lingling Zhang, Zhenping Wen, Jun Liang

BMC Gastroenterol. 2024; 24: 11. Published online 2024 Jan 2. doi: 10.1186/s12876-023-03059-w

PMCID:: PMC10759659

Abstract Article PDF–7.4M

Select item 1070988413.

ARID1A loss activates MAPK signaling via DUSP4 downregulation

Jayaprakash Mandal, Zheng-Cheng Yu, Ie-Ming Shih, Tian-Li Wang

J Biomed Sci. 2023; 30: 94. Published online 2023 Dec 9. doi: 10.1186/s12929-023-00985-5

PMCID:: PMC10709884

Abstract Article PDF–5.3M

Select item 1069462414.

Targeting the TCA cycle through cuproptosis confers synthetic lethality on ARID1A-deficient hepatocellular carcinoma

Tao Xing, Li Li, Yiran Chen, Gaoda Ju, Guilan Li, Xiaoyun Zhu, Yubo Ren, Jing Zhao, Zhilei Cheng, Yan Li, Da Xu, Jun Liang

Cell Rep Med. 2023 Nov 21; 4(11): 101264. Published online 2023 Nov 7. doi: 10.1016/j.xcrm.2023.101264

PMCID:: PMC10694624

Abstract Article PDF–6.5M

Select item 1068449915.

Coexistent ARID1A-PIK3CA mutations are associated with immune-related pathways in luminal breast cancer

Liat Anabel Sinberger, Tamar Zahavi, Amir Sonnenblick, Mali Salmon‐Divon

Sci Rep. 2023; 13: 20911. Published online 2023 Nov 27. doi: 10.1038/s41598-023-48002-x

PMCID:: PMC10684499

Abstract Article PDF–4.2M

Select item 1056587616.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 1050814017.

Low level of ARID1A contributes to adaptive immune resistance and sensitizes triple‐negative breast cancer to immune checkpoint inhibitors

Xin‐Yu Chen, Bin Li, Ye Wang, Juan Jin, Yu Yang, Lei‐Huan Huang, Meng‐Di Yang, Jian Zhang, Bi‐Yun Wang, Zhi‐Ming Shao, Ting Ni, Sheng‐Lin Huang, Xi‐Chun Hu, Zhong‐Hua Tao

Cancer Commun (Lond) 2023 Sep; 43(9): 1003–1026. Published online 2023 Jul 11. doi: 10.1002/cac2.12465

PMCID:: PMC10508140

Abstract Article PDF–9.6M

Select item 1038107118.

DHX38 restricts chemoresistance by regulating the alternative pre-mRNA splicing of RELL2 in pancreatic ductal adenocarcinoma

Zeru Li, Cheng Qin, Bangbo Zhao, Yuanyang Wang, Tianyu Li, Yutong Zhao, Weibin Wang

PLoS Genet. 2023 Jul; 19(7): e1010847. Published online 2023 Jul 28. doi: 10.1371/journal.pgen.1010847

PMCID:: PMC10381071

Abstract Article PDF–3.1M

Select item 1023742219.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1020265520.

Optimized whole-genome CRISPR interference screens identify ARID1A-dependent growth regulators in human induced pluripotent stem cells

Sunay Usluer, Pille Hallast, Luca Crepaldi, Yan Zhou, Katie Urgo, Cansu Dincer, Jing Su, Guillaume Noell, Kaur Alasoo, Omar El Garwany, Sebastian S. Gerety, Ben Newman, Oliver M. Dovey, Leopold Parts

Stem Cell Reports. 2023 May 9; 18(5): 1061–1074. Published online 2023 Apr 6. doi: 10.1016/j.stemcr.2023.03.008

PMCID:: PMC10202655

Abstract Article PDF–4.7M

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