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Select item 100339371.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 88970222.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 71699834.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 55316115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 40361946.

Crystal Structure and Molecular Imaging of the Na_v Channel β3 Subunit Indicates a Trimeric Assembly

Sivakumar Namadurai, Dilshan Balasuriya, Rajit Rajappa, Martin Wiemhöfer, Katherine Stott, Jurgen Klingauf, J. Michael Edwardson, Dimitri Y. Chirgadze, Antony P. Jackson

J Biol Chem. 2014 Apr 11; 289(15): 10797–10811. Published online 2014 Feb 24. doi: 10.1074/jbc.M113.527994

PMCID:: PMC4036194

Abstract Article PDF–4.6M

Select item 37299277.

Genome-wide Association Study Identifies Multiple Risk Loci for Chronic Lymphocytic Leukemia

Sonja I. Berndt, Christine F. Skibola, Vijai Joseph, Nicola J. Camp, Alexandra Nieters, Zhaoming Wang, Wendy Cozen, Alain Monnereau, Sophia S. Wang, Rachel S. Kelly, Qing Lan, Lauren R. Teras, Nilanjan Chatterjee, Charles C. Chung, Meredith Yeager, Angela R. Brooks-Wilson, Patricia Hartge, Mark P. Purdue, Brenda M. Birmann, Bruce K. Armstrong, Pierluigi Cocco, Yawei Zhang, Gianluca Severi, Anne Zeleniuch-Jacquotte, Charles Lawrence, Laurie Burdette, Jeffrey Yuenger, Amy Hutchinson, Kevin B. Jacobs, Timothy G. Call, Tait D. Shanafelt, Anne J. Novak, Neil E. Kay, Mark Liebow, Alice H. Wang, Karin E Smedby, Hans-Olov Adami, Mads Melbye, Bengt Glimelius, Ellen T. Chang, Martha Glenn, Karen Curtin, Lisa A. Cannon-Albright, Brandt Jones, W. Ryan Diver, Brian K. Link, George J. Weiner, Lucia Conde, Paige M. Bracci, Jacques Riby, Elizabeth A. Holly, Martyn T. Smith, Rebecca D. Jackson, Lesley F. Tinker, Yolanda Benavente, Nikolaus Becker, Paolo Boffetta, Paul Brennan, Lenka Foretova, Marc Maynadie, James McKay, Anthony Staines, Kari G. Rabe, Sara J. Achenbach, Celine M. Vachon, Lynn R Goldin, Sara S. Strom, Mark C. Lanasa, Logan G. Spector, Jose F. Leis, Julie M. Cunningham, J. Brice Weinberg, Vicki A. Morrison, Neil E. Caporaso, Aaron D. Norman, Martha S. Linet, Anneclaire J. De Roos, Lindsay M. Morton, Richard K. Severson, Elio Riboli, Paolo Vineis, Rudolph Kaaks, Dimitrios Trichopoulos, Giovanna Masala, Elisabete Weiderpass, María-Dolores Chirlaque, Roel C H Vermeulen, Ruth C. Travis, Graham G. Giles, Demetrius Albanes, Jarmo Virtamo, Stephanie Weinstein, Jacqueline Clavel, Tongzhang Zheng, Theodore R Holford, Kenneth Offit, Andrew Zelenetz, Robert J. Klein, John J. Spinelli, Kimberly A. Bertrand, Francine Laden, Edward Giovannucci, Peter Kraft, Anne Kricker, Jenny Turner, Claire M. Vajdic, Maria Grazia Ennas, Giovanni M. Ferri, Lucia Miligi, Liming Liang, Joshua Sampson, Simon Crouch, Ju-hyun Park, Kari E. North, Angela Cox, John A. Snowden, Josh Wright, Angel Carracedo, Carlos Lopez-Otin, Silvia Bea, Itziar Salaverria, David Martin, Elias Campo, Joseph F. Fraumeni, Jr, Silvia de Sanjose, Henrik Hjalgrim, James R. Cerhan, Stephen J. Chanock, Nathaniel Rothman, Susan L. Slager

Nat Genet. Author manuscript; available in PMC 2014 Feb 1.

Published in final edited form as: Nat Genet. 2013 Aug; 45(8): 868–876. Published online 2013 Jun 16. doi: 10.1038/ng.2652

PMCID:: PMC3729927

Article PDF–1.8M

Select item 35838458.

The immunoglobulin domain of the sodium channel β3 subunit contains a surface-localized disulfide bond that is required for homophilic binding

Nikitha R. Yereddi, Fiona S. Cusdin, Sivakumar Namadurai, Len C. Packman, Tom P. Monie, Peter Slavny, Jeffrey J. Clare, Andrew J. Powell, Antony P. Jackson

FASEB J. 2013 Feb; 27(2): 568–580. doi: 10.1096/fj.12-209445

PMCID:: PMC3583845

Abstract Article

Select item 32083319.

Multiple arrhythmic syndromes in a newborn, owing to a novel mutation in SCN5A

Kirstine Calloe, Nicole Schmitt, Soren Grubb, Ryan Pfeiffer, Jens-Peter David, Ronald Kanter, Jonathan M. Cordeiro, Charles Antzelevitch

Can J Physiol Pharmacol. Author manuscript; available in PMC 2012 Oct 1.

Published in final edited form as: Can J Physiol Pharmacol. 2011 Oct; 89(10): 723–736. Published online 2011 Sep 6. doi: 10.1139/y11-070

PMCID:: PMC3208331

Abstract Article PDF–3.0M

Select item 317805910.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 313208111.

Functional dominant-negative mutation of sodium channel subunit gene SCN3B associated with atrial fibrillation in a Chinese GeneID population

Pengyun Wang, Qinbo Yang, Xiaofen Wu, Yanzong Yang, Lisong Shi, Chuchu Wang, Gang Wu, Yunlong Xia, Bo Yang, Rongfeng Zhang, Chengqi Xu, Xiang Cheng, Sisi Li, Yuanyuan Zhao, Fenfen Fu, Yuhua Liao, Fang Fang, Qiuyun Chen, Xin Tu, Qing K. Wang

Biochem Biophys Res Commun. Author manuscript; available in PMC 2011 Jul 16.

Published in final edited form as: Biochem Biophys Res Commun. 2010 Jul 16; 398(1): 98–104. doi: 10.1016/j.bbrc.2010.06.042

PMCID:: PMC3132081

Abstract Article PDF–1.9M

Select item 296340212.

The Sodium Channel β3-Subunit Induces Multiphasic Gating in Na_V1.3 and Affects Fast Inactivation via Distinct Intracellular Regions

Fiona S. Cusdin, Daniel Nietlispach, Joseph Maman, Timothy J. Dale, Andrew J. Powell, Jeffrey J. Clare, Antony P. Jackson

J Biol Chem. 2010 Oct 22; 285(43): 33404–33412. Published online 2010 Jul 30. doi: 10.1074/jbc.M110.114058

PMCID:: PMC2963402

Abstract Article PDF–2.2M

Select item 290968013.

Sudden Infant Death Syndrome-Associated Mutations in the Sodium Channel Beta Subunits

Bi-Hua Tan, Kavitha N Pundi, David W Van Norstrand, Carmen R Valdivia, David J Tester, Argelia Medeiros-Domingo, Jonathan C. Makielski, Michael J. Ackerman

Heart Rhythm. Author manuscript; available in PMC 2011 Jun 1.

Published in final edited form as: Heart Rhythm. 2010 Jun; 7(6): 771–778. Published online 2010 Feb 1. doi: 10.1016/j.hrthm.2010.01.032

PMCID:: PMC2909680

Abstract Article PDF–1.9M

Select item 286817514.

Loss-of-function mutation of the SCN3B-encoded sodium channel β3 subunit associated with a case of idiopathic ventricular fibrillation

Carmen R. Valdivia, Argelia Medeiros-Domingo, Bin Ye, Win-Kuang Shen, Timothy J. Algiers, Michael J. Ackerman, Jonathan C. Makielski

Cardiovasc Res. 2010 Jun 1; 86(3): 392–400. Published online 2009 Dec 30. doi: 10.1093/cvr/cvp417

PMCID:: PMC2868175

Abstract Article PDF–465K

Select item 274494515.

The voltage-gated Na⁺ channel β3 subunit does not mediate trans homophilic cell adhesion or associate with the cell adhesion molecule contactin

Dyke P. McEwen, Chunling Chen, Laurence S. Meadows, Luis Lopez-Santiago, Lori L. Isom

Neurosci Lett. Author manuscript; available in PMC 2010 Sep 25.

Published in final edited form as: Neurosci Lett. 2009 Oct 25; 462(3): 272–275. Published online 2009 Jul 17. doi: 10.1016/j.neulet.2009.07.020

PMCID:: PMC2744945

Abstract Article PDF–747K

Select item 272772516.

Mutations in Sodium Channel Beta1 and Beta2 Subunits Associated with Atrial Fibrillation

Hiroshi Watanabe, Dawood Darbar, Daniel W Kaiser, Kim Jiramongkolchai, Sameer Chopra, Brian S. Donahue, Prince J. Kannankeril, Dan M. Roden

Circ Arrhythm Electrophysiol. Author manuscript; available in PMC 2010 Jun 1.

Published in final edited form as: Circ Arrhythm Electrophysiol. 2009 Jun; 2(3): 268–275. Published online 2009 Mar 6. doi: 10.1161/CIRCEP.108.779181

PMCID:: PMC2727725

Abstract Article PDF–4.4M

Select item 256455517.

High throughput SNP and expression analyses of candidate genes for non‐syndromic oral clefts

J W Park, J Cai, I McIntosh, E W Jabs, M D Fallin, R Ingersoll, J B Hetmanski, M Vekemans, T Attie‐Bitach, M Lovett, A F Scott, T H Beaty

J Med Genet. 2006 Jul; 43(7): 598–608. Published online 2006 Jan 13. doi: 10.1136/jmg.2005.040162

PMCID:: PMC2564555

Abstract Article PDF–2.0M

Select item 215077918.

Sodium channel β1 and β3 subunits associate with neurofascin through their extracellular immunoglobulin-like domain

Charlotte F. Ratcliffe, Ruth E. Westenbroek, Rory Curtis, William A. Catterall

J Cell Biol. 2001 Jul 23; 154(2): 427–434. doi: 10.1083/jcb.200102086

PMCID:: PMC2150779

Abstract Article PDF–233K

Select item 135612919.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 134750120.

The LIFEdb database in 2006

Alexander Mehrle, Heiko Rosenfelder, Ingo Schupp, Coral del Val, Dorit Arlt, Florian Hahne, Stephanie Bechtel, Jeremy Simpson, Oliver Hofmann, Winston Hide, Karl-Heinz Glatting, Wolfgang Huber, Rainer Pepperkok, Annemarie Poustka, Stefan Wiemann

Nucleic Acids Res. 2006 Jan 1; 34(Database issue): D415–D418. Published online 2005 Dec 28. doi: 10.1093/nar/gkj139

PMCID:: PMC1347501

Abstract Article PDF–301K

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