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Select item 111094831.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 110932122.

SMYD4 monomethylates PRMT5 and forms a positive feedback loop to promote hepatocellular carcinoma progression

Zhenyu Zhou, Zheng Chen, Qianlei Zhou, Shiyu Meng, Juanyi Shi, Sintim Mui, Hai Jiang, Jianhong Lin, Gui He, Wenbin Li, Jianlong Zhang, Jie Wang, Chuanchao He, Yongcong Yan, Zhiyu Xiao

Cancer Sci. 2024 May; 115(5): 1587–1601. Published online 2024 Mar 4. doi: 10.1111/cas.16139

PMCID:: PMC11093212

Abstract Article PDF–68M

Select item 110871093.

Identification of protein methyltransferases 5 associated with ferroptosis and immune cell infiltration of head and neck squamous cell carcinoma

Xiaoyue Zhang, Qiang Liu, Lujuan Wang, Qiu Peng

Aging (Albany NY) 2024 Apr 30; 16(8): 7426–7436. Published online 2024 Apr 25. doi: 10.18632/aging.205768

PMCID:: PMC11087109

Abstract Article PDF–2.6M

Select item 110720214.

PRMT5-mediated RNF4 methylation promotes therapeutic resistance of APL cells to As₂O₃ by stabilizing oncoprotein PML-RARα

Xinping Huang, Yongfeng Yang, Dan Zhu, Yan Zhao, Min Wei, Ke Li, Hong-hu Zhu, Xiaofeng Zheng

Cell Mol Life Sci. 2022 Jun; 79(6): 319. Published online 2022 May 27. doi: 10.1007/s00018-022-04358-3

PMCID:: PMC11072021

Abstract Article PDF–9.5M

Select item 110204945.

CircPRMT5 promotes progression of osteosarcoma by recruiting CNBP to regulate the translation and stability of CDK6 mRNA

Yunlu Liu, Hongyan Jiang, Keli Hu, Hui Zou, Weiguo Zhang, Jiangtao Liu, Xiaofei Jian

PLoS One. 2024; 19(4): e0298947. Published online 2024 Apr 16. doi: 10.1371/journal.pone.0298947

PMCID:: PMC11020494

Abstract Article PDF–4.3M

Select item 109321506.

Inhibition of PRMT5/MEP50 Arginine Methyltransferase Activity Causes Cancer Vulnerability in NDRG2^low Adult T-Cell Leukemia/Lymphoma

Tomonaga Ichikawa, Akira Suekane, Shingo Nakahata, Hidekatsu Iha, Kazuya Shimoda, Takashi Murakami, Kazuhiro Morishita

Int J Mol Sci. 2024 Mar; 25(5): 2842. Published online 2024 Feb 29. doi: 10.3390/ijms25052842

PMCID:: PMC10932150

Abstract Article PDF–3.7M

Select item 107167227.

PRMT5 participates in B cell overactivation in patients with primary Sjogren's syndrome (pSS) through RSAD2‐mediated NF‐κB signaling

Hong Zhu, Jian Zheng, Yan Zhou, Tong Wu, Tiantian Zhu

Immun Inflamm Dis. 2023 Dec; 11(12): e1102. Published online 2023 Dec 13. doi: 10.1002/iid3.1102

PMCID:: PMC10716722

Abstract Article PDF–2.0M

Select item 106904688.

MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression

Yan Sun, Xin Jin, Junpeng Meng, Feng Guo, Taoyu Chen, Xiaoyan Zhao, Heshui Wu, Dianyun Ren

EMBO J. 2023 Dec; 42(23): e114558. Published online 2023 Oct 31. doi: 10.15252/embj.2023114558

PMCID:: PMC10690468

Abstract Article PDF–17M

Select item 106214839.

Antitumor Effects of PRMT5 Inhibition in Sarcomas

Stéphanie Verbeke, Aurélien Bourdon, Jean-Philippe Guegan, Laura Leroy, Vanessa Chaire, Elodie Richard, Alban Bessede, Antoine Italiano

Cancer Res Commun. 2023 Nov; 3(11): 2211–2220. Published online 2023 Nov 2. doi: 10.1158/2767-9764.CRC-23-0239

PMCID:: PMC10621483

Abstract Article PDF–7.1M

Select item 1057891510.

Epigenetic regulation of vascular smooth muscle cell phenotypic switch and neointimal formation by PRMT5

Ni Zhu, Zhi-Fu Guo, Kyosuke Kazama, Bing Yi, Nopprarat Tongmuang, Huijuan Yao, Ruifeng Yang, Chen Zhang, Yongwen Qin, Lin Han, Jianxin Sun

Cardiovasc Res. 2023 Aug; 119(12): 2244–2255. Published online 2023 Jul 24. doi: 10.1093/cvr/cvad110

PMCID:: PMC10578915

Abstract Article PDF–1.2M

Select item 1040088411.

PRMT5 triggers glucocorticoid-induced cell migration in triple-negative breast cancer

Lara Malik Noureddine, Julien Ablain, Ausra Surmieliova-Garnès, Julien Jacquemetton, Thuy Ha Pham, Elisabetta Marangoni, Anne Schnitzler, Ivan Bieche, Bassam Badran, Olivier Trédan, Nader Hussein, Muriel Le Romancer, Coralie Poulard

Life Sci Alliance. 2023 Oct; 6(10): e202302009. Published online 2023 Aug 3. doi: 10.26508/lsa.202302009

PMCID:: PMC10400884

Abstract Article PDF–3.5M

Select item 1037397912.

PRMT5 facilitates angiogenesis and EMT via HIF-1α/VEGFR/Akt signaling axis in lung cancer

Yonghua Zheng, Huaxia Ji, Wulin Yi, Zhanjun Chen, Xiaobiao Hu, Jie Zhou, Yang Wang, Xiao Zheng

Aging (Albany NY) 2023 Jul 15; 15(13): 6163–6178. Published online 2023 Jul 3. doi: 10.18632/aging.204826

PMCID:: PMC10373979

Abstract Article PDF–1.6M

Select item 1029091913.

PRMT5 promotes chemotherapy‐induced neuroendocrine differentiation in NSCLC

Qi Shen, Yi Liu, Xuehong Deng, Chang‐Deng Hu

Thorac Cancer. 2023 Jun; 14(18): 1764–1773. Published online 2023 May 4. doi: 10.1111/1759-7714.14921

PMCID:: PMC10290919

Abstract Article PDF–2.2M

Select item 1023742214.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1009467415.

Protein Arginine Methyltransferase 5 (PRMT5) Mutations in Cancer Cells

Shayaan Rasheed, Renee A. Bouley, Ryan J. Yoder, Ruben C. Petreaca

Int J Mol Sci. 2023 Apr; 24(7): 6042. Published online 2023 Mar 23. doi: 10.3390/ijms24076042

PMCID:: PMC10094674

Abstract Article PDF–2.8M

Select item 1004803516.

The Role of PRMT5 in Immuno-Oncology

Yoshinori Abe, Takumi Sano, Nobuyuki Tanaka

Genes (Basel) 2023 Mar; 14(3): 678. Published online 2023 Mar 9. doi: 10.3390/genes14030678

PMCID:: PMC10048035

Abstract Article PDF–2.5M

Select item 1002611117.

PRMT5/FGFR3/AKT Signaling Axis Facilitates Lung Cancer Cell Metastasis

Yonghua Zheng, Jingjing Lu, Xiaoyan Hu, Xiaobiao Hu, Xiwen Gao, Jie Zhou

Technol Cancer Res Treat. 2023; 22: 15330338231161139. Published online 2023 Mar 17. doi: 10.1177/15330338231161139

PMCID:: PMC10026111

Abstract Article PDF–2.5M

Select item 998887618.

USP7- and PRMT5-dependent G3BP2 stabilization drives de novo lipogenesis and tumorigenesis of HNSC

Nan Wang, Tianzi Li, Wanyu Liu, Jinhua Lin, Ke Zhang, Zhenhao Li, Yanfei Huang, Yufei Shi, Meilan Xu, Xuekui Liu

Cell Death Dis. 2023 Mar; 14(3): 182. Published online 2023 Mar 6. doi: 10.1038/s41419-023-05706-2

PMCID:: PMC9988876

Abstract Article PDF–5.7M

Select item 998681719.

METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m⁶A homeostasis

Zhan‐Cheng Zeng, Qi Pan, Yu‐Meng Sun, Heng‐Jing Huang, Xiao‐Tong Chen, Tian‐Qi Chen, Bo He, Hua Ye, Shun‐Xin Zhu, Ke‐Jia Pu, Ke Fang, Wei Huang, Yue‐Qin Chen, Wen‐Tao Wang

EMBO Rep. 2023 Mar; 24(3): e55762. Published online 2023 Jan 4. doi: 10.15252/embr.202255762