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Select item 109291811.

WTAP Mediated N6-methyladenosine RNA Modification of ELF3 Drives Cellular Senescence by Upregulating IRF8

Lei Zhou, Yun Zhong, Fan Wang, Yi Guo, Rui Mao, Hongfu Xie, Yiya Zhang, Ji Li

Int J Biol Sci. 2024; 20(5): 1763–1777. Published online 2024 Feb 25. doi: 10.7150/ijbs.90459

PMCID:: PMC10929181

Abstract Article PDF–6.5M

Select item 102366172.

An integrative epigenomic approach identifies ELF3 as an oncogenic regulator in ASCL1‐positive neuroendocrine carcinoma

Masafumi Horie, Hidenori Tanaka, Masami Suzuki, Yoshihiko Sato, So Takata, Erina Takai, Naoya Miyashita, Akira Saito, Yoichiro Nakatani, Shinichi Yachida

Cancer Sci. 2023 Jun; 114(6): 2596–2608. Published online 2023 Mar 15. doi: 10.1111/cas.15764

PMCID:: PMC10236617

Abstract Article PDF–3.5M

Select item 100281533.

ESE1/AGR2 axis antagonizes TGF‐β‐induced epithelial‐mesenchymal transition in low‐grade pancreatic cancer

Hui‐Jing Xu, Jing Bai, Ye Tian, Xiao Feng, Ai‐Ping Chen, Jie Wang, Jin Wu, Xu‐Ru Jin, Feng Zhang, Mei‐Yu Quan, Chengshui Chen, Kwang‐youl Lee, Jin‐San Zhang

Cancer Med. 2023 Mar; 12(5): 5979–5993. Published online 2022 Nov 3. doi: 10.1002/cam4.5397

PMCID:: PMC10028153

Abstract Article PDF–9.5M

Select item 98101894.

MYB and ELF3 differentially modulate labor-inducing gene expression in myometrial cells

Virlana M. Shchuka, Nawrah Khader, Anna Dorogin, Oksana Shynlova, Jennifer A. Mitchell

PLoS One. 2023; 18(1): e0271081. Published online 2023 Jan 3. doi: 10.1371/journal.pone.0271081

PMCID:: PMC9810189

Abstract Article PDF–1.4M

Select item 97167515.

LncRNA ELF3-AS1 inhibits gastric cancer by forming a negative feedback loop with SNAI2 and regulates ELF3 mRNA stability via interacting with ILF2/ILF3 complex

Dandan Li, Li Shen, Xudong Zhang, Zhen Chen, Pan Huang, Congcong Huang, Shanshan Qin

J Exp Clin Cancer Res. 2022; 41: 332. Published online 2022 Dec 2. doi: 10.1186/s13046-022-02541-9

PMCID:: PMC9716751

Abstract Article PDF–13M

Select item 93464696.

Hypoxia‐induced ELF3 promotes tumor angiogenesis through IGF1/IGF1R

Seung Hee Seo, Soo‐Yeon Hwang, Seohui Hwang, Sunjung Han, Hyojin Park, Yun‐Sil Lee, Seung Bae Rho, Youngjoo Kwon

EMBO Rep. 2022 Aug; 23(8): e52977. Published online 2022 Jun 13. doi: 10.15252/embr.202152977

PMCID:: PMC9346469

Abstract Article PDF–2.9M

Select item 92493417.

ETS transcription factor ELF3 (ESE‐1) is a cell cycle regulator in benign and malignant prostate

Leanne K. Archer, Fiona M. Frame, Hannah F. Walker, Alastair P. Droop, Georgina L. K. McDonald, Samuel Kucko, Daniel M. Berney, Vincent M. Mann, Matthew S. Simms, Norman J. Maitland

FEBS Open Bio. 2022 Jul; 12(7): 1365–1387. Published online 2022 May 6. doi: 10.1002/2211-5463.13417

PMCID:: PMC9249341

Abstract Article PDF–4.8M

Select item 89631318.

ELF3 mediates IL-1α induced differentiation of mesenchymal stem cells to inflammatory iCAFs

Linda L. Tran, Truong Dang, Rintu Thomas, David R. Rowley

Stem Cells. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Stem Cells. 2021 Dec; 39(12): 1766–1777. Published online 2021 Oct 7. doi: 10.1002/stem.3455

PMCID:: PMC8963131

Abstract Article PDF–1.1M

Select item 88288959.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 862047910.

ELF3 Is a Target That Promotes Therapeutic Efficiency in EGFR Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer Cells via Inhibiting PKCί

Jeon-Soo Lee, Young Eun Choi, Sunshin Kim, Ji-Youn Han, Sung-Ho Goh

Int J Mol Sci. 2021 Nov; 22(22): 12287. Published online 2021 Nov 13. doi: 10.3390/ijms222212287

PMCID:: PMC8620479

Abstract Article PDF–5.2M

Select item 851905611.

Vorinostat ameliorates IL‐1α‐induced reduction of type II collagen by inhibiting the expression of ELF3 in chondrocytes

Xudong Miao, Yongping Wu, Ping Wang, Qiang Zhang, Chenhe Zhou, Xinning Yu, Le Cao

J Biochem Mol Toxicol. 2021 Sep; 35(9): e22844. Published online 2021 Jul 11. doi: 10.1002/jbt.22844

PMCID:: PMC8519056

Abstract Article PDF–2.7M

Select item 822773212.

Nanopore Sequencing Unveils Diverse Transcript Variants of the Epithelial Cell-Specific Transcription Factor Elf-3 in Human Malignancies

Michaela A. Boti, Panagiotis G. Adamopoulos, Panagiotis Tsiakanikas, Andreas Scorilas

Genes (Basel) 2021 Jun; 12(6): 839. Published online 2021 May 29. doi: 10.3390/genes12060839

PMCID:: PMC8227732

Abstract Article PDF–1.4M

Select item 802650613.

A transcriptional regulatory loop of master regulator transcription factors, PPARG, and fatty acid synthesis promotes esophageal adenocarcinoma

Sai Ma, Bo Zhou, Qian Yang, Yunzhi Pan, Wei Yang, Stephen J. Freedland, Ling-Wen Ding, Michael R. Freeman, Joshua J. Breunig, Neil A. Bhowmick, Jian Pan, H. Phillip Koeffler, De-Chen Lin

Cancer Res. Author manuscript; available in PMC 2021 Sep 1.

Published in final edited form as: Cancer Res. 2021 Mar 1; 81(5): 1216–1229. Published online 2021 Jan 5. doi: 10.1158/0008-5472.CAN-20-0652

PMCID:: PMC8026506

Abstract Article PDF–1.4M

Select item 800904814.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 793634915.

ELF3 activated by a superenhancer and an autoregulatory feedback loop is required for high-level HLA-C expression on extravillous trophoblasts

Qin Li, Torsten B. Meissner, Fang Wang, Ziming Du, Sai Ma, Sarika Kshirsagar, Tamara Tilburgs, Jason D. Buenrostro, Motonari Uesugi, Jack L. Strominger

Proc Natl Acad Sci U S A. 2021 Mar 2; 118(9): e2025512118. Published online 2021 Feb 23. doi: 10.1073/pnas.2025512118

PMCID:: PMC7936349

Abstract Article PDF–1.2M

Select item 789874516.

FZD5 prevents epithelial-mesenchymal transition in gastric cancer

Dan Dong, Lei Na, Kailing Zhou, Zhuo Wang, Yu Sun, Qianqian Zheng, Jian Gao, Chenghai Zhao, Wei Wang

Cell Commun Signal. 2021; 19: 21. Published online 2021 Feb 22. doi: 10.1186/s12964-021-00708-z

PMCID:: PMC7898745

Abstract Article PDF–7.2M

Select item 788072217.

ELF3 Overexpression as Prognostic Biomarker for Recurrence of Stage II Colorectal Cancer

AYUMI TAKAOKA, TOSHIAKI ISHIKAWA, SATOSHI OKAZAKI, SHUICHI WATANABE, FUYUKI MIYA, TATSUHIKO TSUNODA, AKIFUMI KIKUCHI, SHINICHI YAMAUCHI, TAKATOSHI MATSUYAMA, MASANORI TOKUNAGA, HIROYUKI UETAKE, YUSUKE KINUGASA

In Vivo. 2021 Jan-Feb; 35(1): 191–201. Published online 2021 Jan 3. doi: 10.21873/invivo.12248

PMCID:: PMC7880722

Abstract Article PDF–2.5M

Select item 749056018.

A functionally defined high-density NRF2 interactome reveals new conditional regulators of ARE transactivation

Jonathan Poh, Amy H. Ponsford, James Boyd, Jonathan Woodsmith, Ulrich Stelzl, Erich Wanker, Nicholas Harper, David MacEwan, Christopher M. Sanderson

Redox Biol. 2020 Oct; 37: 101686. Published online 2020 Aug 20. doi: 10.1016/j.redox.2020.101686

PMCID:: PMC7490560

Abstract Article PDF–8.6M

Select item 744528819.

Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate

Akhilesh Pandey, Eric W. Stawiski, Steffen Durinck, Harsha Gowda, Leonard D. Goldstein, Mustafa A. Barbhuiya, Markus S. Schröder, Sreelakshmi K. Sreenivasamurthy, Sun-Whe Kim, Sameer Phalke, Kushal Suryamohan, Kayla Lee, Papia Chakraborty, Vasumathi Kode, Xiaoshan Shi, Aditi Chatterjee, Keshava Datta, Aafaque A. Khan, Tejaswini Subbannayya, Jing Wang, Subhra Chaudhuri, Sanjiv Gupta, Braj Raj Shrivastav, Bijay S. Jaiswal, Satish S. Poojary, Shushruta Bhunia, Patricia Garcia, Carolina Bizama, Lorena Rosa, Wooil Kwon, Hongbeom Kim, Youngmin Han, Thakur Deen Yadav, Vedam L. Ramprasad, Amitabha Chaudhuri, Zora Modrusan, Juan Carlos Roa, Pramod Kumar Tiwari, Jin-Young Jang, Somasekar Seshagiri

Nat Commun. 2020; 11: 4225. Published online 2020 Aug 24. doi: 10.1038/s41467-020-17880-4

PMCID:: PMC7445288

Abstract Article PDF–16M

Select item 724246420.

High glucose mediates NLRP3 inflammasome activation via upregulation of ELF3 expression

Jing Wang, Xuefang Shen, Jing Liu, Wankun Chen, Fengfeng Wu, Weifei Wu, Zhipeng Meng, Minmin Zhu, Changhong Miao

Cell Death Dis. 2020 May; 11(5): 383. Published online 2020 May 21. doi: 10.1038/s41419-020-2598-6

PMCID:: PMC7242464

Abstract Article PDF–5.0M

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