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Select item 110023081.

Melanoma-associated melanocortin 1 receptor variants confer redox signaling-dependent protection against oxidative DNA damage

María Castejón-Griñán, Sonia Cerdido, José Sánchez-Beltrán, Ana Lambertos, Marta Abrisqueta, Cecilia Herraiz, Celia Jiménez-Cervantes, José Carlos García-Borrón

Redox Biol. 2024 Jun; 72: 103135. Published online 2024 Mar 26. doi: 10.1016/j.redox.2024.103135

PMCID:: PMC11002308

Abstract Article PDF–10M

Select item 105324032.

A Side-by-Side Comparison of Wildtype and Variant Melanocortin 1 Receptor Signaling with Emphasis on Protection against Oxidative Damage to DNA

Sonia Cerdido, José Sánchez-Beltrán, Ana Lambertos, Marta Abrisqueta, Lidia Padilla, Cecilia Herraiz, Conchi Olivares, Celia Jiménez-Cervantes, José C. García-Borrón

Int J Mol Sci. 2023 Sep; 24(18): 14381. Published online 2023 Sep 21. doi: 10.3390/ijms241814381

PMCID:: PMC10532403

Abstract Article PDF–2.6M

Select item 105042823.

Activation of melanocortin-1 receptor signaling in melanoma cells impairs T cell infiltration to dampen antitumor immunity

Yazhong Cui, Yang Miao, Longzhi Cao, Lifang Guo, Yue Cui, Chuanzhe Yan, Zhi Zeng, Mo Xu, Ting Han

Nat Commun. 2023; 14: 5740. Published online 2023 Sep 15. doi: 10.1038/s41467-023-41101-3

PMCID:: PMC10504282

Abstract Article PDF–2.0M

Select item 104633884.

Alpha-melanocyte stimulating hormone (α-MSH): biology, clinical relevance and implication in melanoma

Luigi Dall’Olmo, Nicole Papa, Nicoletta Concetta Surdo, Ilaria Marigo, Simone Mocellin

J Transl Med. 2023; 21: 562. Published online 2023 Aug 22. doi: 10.1186/s12967-023-04405-y

PMCID:: PMC10463388

Abstract Article PDF–856K

Select item 104184755.

Melanocortin 1 Receptor (MC1R): Pharmacological and Therapeutic Aspects

Yoonwoo Mun, Woohyun Kim, Dongyun Shin

Int J Mol Sci. 2023 Aug; 24(15): 12152. Published online 2023 Jul 29. doi: 10.3390/ijms241512152

PMCID:: PMC10418475

Abstract Article PDF–2.5M

Select item 102309616.

The MC1R r allele does not increase melanoma risk in MITF E318K carriers

Courtney K Wallingford, Anastassia Demeshko, Asha Krishnankutty Krishnakripa, Darren J Smit, David L Duffy, Brigid Betz-Stablein, Annette Pflugfelder, Kasturee Jagirdar, Elizabeth Holland, Graham J Mann, Clare A Primiero, Tatiane Yanes, Josep Malvehy, Cèlia Badenas, Cristina Carrera, Paula Aguilera, Catherine M Olsen, Sarah V Ward, Nikolas K Haass, Richard A Sturm, Susana Puig, David C Whiteman, Matthew H Law, Anne E Cust, Miriam Potrony, H Peter Soyer, Aideen M McInerney-Leo

Br J Dermatol. 2023 Jun; 188(6): 770–776. Published online 2023 Mar 5. doi: 10.1093/bjd/ljad041

PMCID:: PMC10230961

Abstract Article PDF–850K

Select item 100733417.

AMPK phosphorylates ZDHHC13 to increase MC1R activity and suppress melanomagenesis

Yu Sun, Xin Li, Chengqian Yin, Judy Zhang, Ershang Liang, Xianfang Wu, Ying Ni, Joshua Arbesman, Colin R Goding, Shuyang Chen

Cancer Res. Author manuscript; available in PMC 2023 Oct 4.

Published in final edited form as: Cancer Res. 2023 Apr 4; 83(7): 1062–1073. doi: 10.1158/0008-5472.CAN-22-2595

PMCID:: PMC10073341

Abstract Article PDF–1.9M

Select item 98045798.

Common genetic variants associated with melanoma risk or naevus count in patients with wildtype MC1R melanoma

Neus Calbet‐Llopart, Marc Combalia, Anil Kiroglu, Miriam Potrony, Gemma Tell‐Martí, Andrea Combalia, Albert Brugues, Sebastian Podlipnik, Cristina Carrera, Susana Puig, Josep Malvehy, Joan Anton Puig‐Butillé

Br J Dermatol. 2022 Nov; 187(5): 753–764. Published online 2022 Aug 11. doi: 10.1111/bjd.21707

PMCID:: PMC9804579

Abstract Article PDF–977K

Select item 95317089.

Sequence Polymorphisms of MC1R Gene and their Association Analysis with Depression and Antidepressant Response

Gui-Sheng Wu, Huai-Rong Luo, Chuanhui Dong, Claudio Mastronardi, Julio Licinio, Ma-Li Wong

Psychiatr Genet. Author manuscript; available in PMC 2022 Oct 4.

Published in final edited form as: Psychiatr Genet. 2011 Feb; 21(1): 14–18. doi: 10.1097/YPG.0b013e32834133d2

PMCID:: PMC9531708

Abstract Article PDF–332K

Select item 927497810.

Assessment of melanoma precision prevention materials incorporating MC1R genetic risk information

John Charles A Lacson, Stephanie M Forgas, Scarlet H Doyle, Lu Qian, Jocelyn Del Rio, Stella Valavanis, Rodrigo Carvajal, Guillermo Gonzalez-Calderon, Youngchul Kim, Richard G Roetzheim, Susan T Vadaparampil, Peter A Kanetsky

Transl Behav Med. 2022 May; 12(5): 683–687. Published online 2022 May 12. doi: 10.1093/tbm/ibac034

PMCID:: PMC9274978

Abstract Article PDF–1.1M

Select item 903236711.

Genetic diversity of the melanocortin-1 receptor in an admixed population of Rio de Janeiro: Structural and functional impacts of Cys35Tyr variant

Vanessa Neitzke-Montinelli, Priscila da Silva Figueiredo Celestino Gomes, Pedro G. Pascutti, Rodrigo S. Moura-Neto, Rosane Silva

PLoS One. 2022; 17(4): e0267286. Published online 2022 Apr 22. doi: 10.1371/journal.pone.0267286

PMCID:: PMC9032367

Abstract Article PDF–1.1M

Select item 892903712.

MC1R Is a Prognostic Marker and Its Expression Is Correlated with MSI in Colorectal Cancer

Lixiong Peng, Jiang Chang, Xilin Liu, Shiying Lu, Honglin Ren, Xiaoshi Zhou, Zengshan Liu, Pan Hu

Curr Issues Mol Biol. 2021 Dec; 43(3): 1529–1547. Published online 2021 Oct 11. doi: 10.3390/cimb43030108

PMCID:: PMC8929037

Abstract Article PDF–5.9M

Select item 882889513.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 855290714.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 848676115.

Structural mechanism of calcium-mediated hormone recognition and Gβ interaction by the human melanocortin-1 receptor

Shanshan Ma, Yan Chen, Antao Dai, Wanchao Yin, Jia Guo, Dehua Yang, Fulai Zhou, Yi Jiang, Ming-Wei Wang, H. Eric Xu

Cell Res. 2021 Oct; 31(10): 1061–1071. Published online 2021 Aug 27. doi: 10.1038/s41422-021-00557-y

PMCID:: PMC8486761

Abstract Article PDF–4.7M

Select item 833043716.

DERMOSCOPIC FEATURES OF CUTANEOUS MELANOMA ARE ASSOCIATED WITH CLINICAL CHARACTERISTICS OF PATIENTS AND TUMORS AND WITH MC1R GENOTYPE

M.C. Fargnoli, F. Sera, M. Suppa, D. Piccolo, M.T. Landi, A. Chiarugi, C. Pellegrini, S. Seidenari, K. Peris

J Eur Acad Dermatol Venereol. Author manuscript; available in PMC 2021 Aug 3.

Published in final edited form as: J Eur Acad Dermatol Venereol. 2014 Dec; 28(12): 1768–1775. Published online 2014 Mar 4. doi: 10.1111/jdv.12411

PMCID:: PMC8330437

Abstract Article PDF–604K

Select item 832792517.

MC1R variants in relation to naevi in melanoma cases and controls: a pooled-analysis from the M-SKIP project

I. Stefanaki, AJ. Stratigos, K.P. Kypreou, E. Evangelou, S. Gandini, P. Maisonneuve, D. Polsky, D. Lazovich, J. Newton-Bishop, P.A. Kanetsky, S. Puig, N.A. Gruis, P. Ghiorzo, C. Pellegrini, A. De Nicolo, G. Ribas, G. Guida, J.C. Garcia-Borron, M.C. Fargnoli, H. Nan, M.T. Landi, J. Little, F. Sera, S. Raimondi, M-SKIP Study Group

J Eur Acad Dermatol Venereol. Author manuscript; available in PMC 2021 Aug 2.

Published in final edited form as: J Eur Acad Dermatol Venereol. 2021 Feb; 35(2): e135–e138. Published online 2020 Sep 6. doi: 10.1111/jdv.16869

PMCID:: PMC8327925

Article PDF–301K

Select item 747926218.

MC1R variants and cutaneous melanoma risk according to histological type, body site, and Breslow thickness: a pooled analysis from the M-SKIP project

Saverio Caini, Sara Gandini, Francesca Botta, Elena Tagliabue, Sara Raimondi, Eduardo Nagore, Ines Zanna, Patrick Maisonneuve, Julia Newton-Bishop, David Polsky, DeAnn Lazovich, Rajiv Kumar, Peter A. Kanetsky, Veronica Hoiom, Paola Ghiorzo, Maria Teresa Landi, Gloria Ribas, Chiara Menin, Alexander J. Stratigos, Giuseppe Palmieri, Gabriella Guida, Jose Carlos García-Borrón, Hongmei Nan, Julian Little, Francesco Sera, Susana Puig, Maria Concetta Fargnoli

Melanoma Res. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: Melanoma Res. 2020 Oct; 30(5): 500–510. doi: 10.1097/CMR.0000000000000668

PMCID:: PMC7479262

Abstract Article PDF–469K

Select item 744009719.

DERMOSCOPIC FEATURES OF MELANOMAS ASSOCIATED WITH MC1R VARIANTS IN SPANISH CDKN2A MUTATION CARRIERS

Francisco Cuéllar, Susana Puig, Isabel Kolm, Joan Puig-Butille, Pedro Zaballos, Rosa Martí-Laborda, Celia Badenas, Josep Malvehy

Br J Dermatol. Author manuscript; available in PMC 2020 Aug 20.

Published in final edited form as: Br J Dermatol. 2009 Jan; 160(1): 48–53. Published online 2008 Sep 15. doi: 10.1111/j.1365-2133.2008.08826.x

PMCID:: PMC7440097

Abstract Article PDF–341K

Select item 720236320.

Detangling red hair from pain: phenotype-specific contributions from different genetic variants in melanocortin-1 receptor

Katerina Zorina-Lichtenwalter, W. Maixner, L. Diatchenko

Pain. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: Pain. 2020 May; 161(5): 938–948. doi: 10.1097/j.pain.0000000000001780

PMCID:: PMC7202363

Article PDF–1.8M

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