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Select item 111426891.

IGF2BP3 regulates the expression of RRM2 and promotes the progression of rheumatoid arthritis via RRM2/Akt/MMP-9 pathway

Zhaonan Ban, Zhengjiang Li, Shuxing Xing, Yongjie Ye

PLoS One. 2024; 19(5): e0303593. Published online 2024 May 31. doi: 10.1371/journal.pone.0303593

PMCID:: PMC11142689

Abstract Article PDF–2.7M

Select item 110259322.

A comprehensive analysis of ribonucleotide reductase subunit M2 for carcinogenesis in pan-cancer

Yong Wang, Rong Chen, Jing Zhang, Peng Zeng

PLoS One. 2024; 19(4): e0299949. Published online 2024 Apr 18. doi: 10.1371/journal.pone.0299949

PMCID:: PMC11025932

Abstract Article PDF–5.2M

Select item 107317023.

Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumor

Le Hien Giang, Kuo-Sheng Wu, Wei-Chung Lee, Shing-Shung Chu, Anh Duy Do, Chun A. Changou, Huy Minh Tran, Tsung-Han Hsieh, Hsin-Hung Chen, Chia-Ling Hsieh, Shian-Ying Sung, Alice L. Yu, Yun Yen, Tai-Tong Wong, Che-Chang Chang

J Exp Clin Cancer Res. 2023; 42: 346. Published online 2023 Dec 20. doi: 10.1186/s13046-023-02911-x

PMCID:: PMC10731702

Abstract Article PDF–5.0M

Select item 102374224.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 102284085.

MiR-17- 5p/RRM2 regulated gemcitabine resistance in lung cancer A549 cells

Xuan Ma, Tian Fu, Zhi-Yin Ke, Shen-Lin Du, Xue-Chun Wang, Ning Zhou, Mu-Yi Zhong, Yong-Jun Liu, Ai-Ling Liang

Cell Cycle. 2023; 22(11): 1367–1379. Published online 2023 Apr 28. doi: 10.1080/15384101.2023.2207247

PMCID:: PMC10228408

Abstract Article PDF–1.5M

Select item 101914466.

Ribonucleotide reductase regulatory subunit M2 drives glioblastoma TMZ resistance through modulation of dNTP production

Ella N. Perrault, Jack M. Shireman, Eunus S. Ali, Peiyu Lin, Isabelle Preddy, Cheol Park, Shreya Budhiraja, Shivani Baisiwala, Karan Dixit, C. David James, Dieter H Heiland, Issam Ben-Sahra, Sebastian Pott, Anindita Basu, Jason Miska, Atique U. Ahmed

Sci Adv. 2023 May; 9(20): eade7236. Published online 2023 May 17. doi: 10.1126/sciadv.ade7236

PMCID:: PMC10191446

Abstract Article PDF–2.4M

Select item 101516157.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 99925198.

Ribonucleotide reductase subunit switching in hepatoblastoma drug response and relapse

Anthony Brown, Qingfei Pan, Li Fan, Emilie Indersie, Cheng Tian, Nikolai Timchenko, Liyuan Li, Baranda S. Hansen, Haiyan Tan, Meifen Lu, Junmin Peng, Shondra M. Pruett-Miller, Jiyang Yu, Stefano Cairo, Liqin Zhu

Commun Biol. 2023; 6: 249. Published online 2023 Mar 8. doi: 10.1038/s42003-023-04630-7

PMCID:: PMC9992519

Abstract Article PDF–15M

Select item 99167149.

NMR Analysis Suggests Synergy between the RRM2 and the Carboxy-Terminal Segment of Human La Protein in the Recognition and Interaction with HCV IRES

Aikaterini I. Argyriou, Georgios A. Machaliotis, Garyfallia I. Makrynitsa, Eleni G. Kaliatsi, Constantinos Stathopoulos, Georgios A. Spyroulias

Int J Mol Sci. 2023 Feb; 24(3): 2572. Published online 2023 Jan 29. doi: 10.3390/ijms24032572

PMCID:: PMC9916714

Abstract Article PDF–3.7M

Select item 987841910.

PRMT1通过促进RRM2表达抑制鼻咽癌细胞凋亡

周兰柱, 吴俊, 张明洁, 赵报, 马士崟

Nan Fang Yi Ke Da Xue Xue Bao. 2022 Dec 20; 42(12): 1783–1790. Chinese. doi: 10.12122/j.issn.1673-4254.2022.12.05

PMCID:: PMC9878419

Abstract Article PDF–2.4M

Select item 959621611.

Comprehensive bioinformatics analysis of ribonucleoside diphosphate reductase subunit M2(RRM2) gene correlates with prognosis and tumor immunotherapy in pan-cancer

Liyuan Wu, Le Yin, Linxiang Ma, Jiarui Yang, Feiya Yang, Baofa Sun, Xing Nianzeng

Aging (Albany NY) 2022 Oct 15; 14(19): 7890–7905. Published online 2022 Oct 3. doi: 10.18632/aging.204315

PMCID:: PMC9596216

Abstract Article PDF–2.6M

Select item 948193312.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 927928513.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 926085614.

FBXO38 Ubiquitin Ligase Controls Centromere Integrity via ZXDA/B Stability

Nikol Dibus, Vladimir Korinek, Lukas Cermak

Front Cell Dev Biol. 2022; 10: 929288. Published online 2022 Jun 23. doi: 10.3389/fcell.2022.929288

Correction in:: Front Cell Dev Biol. 2022; 10: 1000878.

PMCID:: PMC9260856

Abstract Article PDF–2.8M

Select item 917141115.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 889702216.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 880994717.

Ribonucleotide reductase subunit M2 promotes proliferation and epithelial–mesenchymal transition via the JAK2/STAT3 signaling pathway in retinoblastoma

Min Yang, Panpan Yao, Xuqiang Lang, Xue Li, Dawei Zhang

Bioengineered. 2021; 12(2): 12800–12811. Published online 2021 Dec 11. doi: 10.1080/21655979.2021.2001241

PMCID:: PMC8809947

Abstract Article PDF–2.5M

Select item 873436118.

RRM2 expression in different molecular subtypes of breast cancer and its prognostic significance

Manar Ahmed Abdel-Rahman, Mena Mahfouz, Hany Onsy Habashy

Diagn Pathol. 2022; 17: 1. Published online 2022 Jan 5. doi: 10.1186/s13000-021-01174-4

PMCID:: PMC8734361

Abstract Article PDF–729K

Select item 869884319.

RNR-R2 Upregulation by a Short Non-Coding Viral Transcript

Karin Broennimann, Inna Ricardo-Lax, Julia Adler, Eleftherios Michailidis, Ype P. de Jong, Nina Reuven, Yosef Shaul

Biomolecules. 2021 Dec; 11(12): 1822. Published online 2021 Dec 3. doi: 10.3390/biom11121822

PMCID:: PMC8698843

Abstract Article PDF–1.5M

Select item 860245120.

Identification of proximal SUMO-dependent interactors using SUMO-ID

Orhi Barroso-Gomila, Fredrik Trulsson, Veronica Muratore, Iñigo Canosa, Laura Merino-Cacho, Ana Rosa Cortazar, Coralia Pérez, Mikel Azkargorta, Ibon Iloro, Arkaitz Carracedo, Ana M. Aransay, Felix Elortza, Ugo Mayor, Alfred C. O. Vertegaal, Rosa Barrio, James D. Sutherland

Nat Commun. 2021; 12: 6671. Published online 2021 Nov 18. doi: 10.1038/s41467-021-26807-6