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Items: 1 to 20 of 22

1.
Functional spectrum and structural specificity of mitochondrial ferredoxins FDX1 and FDX2
Vinzent Schulz, Somsuvro Basu, Sven-A. Freibert, Holger Webert, Linda Boß, Ulrich Mühlenhoff, Fabien Pierrel, Lars-O. Essen, Douglas M. Warui, Squire Booker, Oliver Stehling, Roland Lill
Nat Chem Biol. Author manuscript; available in PMC 2024 Feb 17.
Published in final edited form as: Nat Chem Biol. 2023 Feb; 19(2): 206–217. Published online 2022 Oct 24. doi: 10.1038/s41589-022-01159-4
PMCID:
PMC10873809
AbstractArticlePDF–6.3M
2.
Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets
Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson
Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8
PMCID:
PMC10499821
AbstractArticlePDF–2.6M
3.
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y
PMCID:
PMC8352964
AbstractArticlePDF–4.5M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
6.
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis
Mohamed Taha Moutaoufik, Ramy Malty, Shahreen Amin, Qingzhou Zhang, Sadhna Phanse, Alla Gagarinova, Mara Zilocchi, Larissa Hoell, Zoran Minic, Maria Gagarinova, Hiroyuki Aoki, Jocelyn Stockwell, Matthew Jessulat, Florian Goebels, Kirsten Broderick, Nichollas E. Scott, James Vlasblom, Gabriel Musso, Bhanu Prasad, Eleonora Lamantea, Barbara Garavaglia, Alex Rajput, Kei Murayama, Yasushi Okazaki, Leonard J. Foster, Gary D. Bader, Francisco S. Cayabyab, Mohan Babu
iScience. 2019 Sep 27; 19: 1114–1132. Published online 2019 Sep 4. doi: 10.1016/j.isci.2019.08.057
PMCID:
PMC6831851
AbstractArticlePDF–9.8M
7.
Physiologically relevant reconstitution of iron-sulfur cluster biosynthesis uncovers persulfide-processing functions of ferredoxin-2 and frataxin
Sylvain Gervason, Djabir Larkem, Amir Ben Mansour, Thomas Botzanowski, Christina S. Müller, Ludovic Pecqueur, Gwenaelle Le Pavec, Agnès Delaunay-Moisan, Omar Brun, Jordi Agramunt, Anna Grandas, Marc Fontecave, Volker Schünemann, Sarah Cianférani, Christina Sizun, Michel B. Tolédano, Benoit D’Autréaux
Nat Commun. 2019; 10: 3566. Published online 2019 Aug 8. doi: 10.1038/s41467-019-11470-9
PMCID:
PMC6687725
AbstractArticlePDF–1.8M
8.
A novel complex neurological phenotype due to a homozygous mutation in FDX2
Juliana Gurgel-Giannetti, David S Lynch, Anderson Rodrigues Brandão de Paiva, Leandro Tavares Lucato, Guilherme Yamamoto, Christer Thomsen, Somsuvro Basu, Fernando Freua, Alexandre Varella Giannetti, Bruno Della Ripa de Assis, Mara Dell Ospedale Ribeiro, Isabella Barcelos, Katiane Sayão Souza, Fernanda Monti, Uirá Souto Melo, Simone Amorim, Leonardo G L Silva, Lúcia Inês Macedo-Souza, Angela M Vianna-Morgante, Michio Hirano, Marjo S Van der Knaap, Roland Lill, Mariz Vainzof, Anders Oldfors, Henry Houlden, Fernando Kok
Brain. 2018 Aug; 141(8): 2289–2298. Published online 2018 Jul 13. doi: 10.1093/brain/awy172
PMCID:
PMC6061701
AbstractArticlePDF–711K
9.
Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex
Michal T. Boniecki, Sven A. Freibert, Ulrich Mühlenhoff, Roland Lill, Miroslaw Cygler
Nat Commun. 2017; 8: 1287. Published online 2017 Nov 3. doi: 10.1038/s41467-017-01497-1
PMCID:
PMC5668364
AbstractArticlePDF–3.2M
10.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
11.
Human Mitochondrial Ferredoxin 1 (FDX1) and Ferredoxin 2 (FDX2) Both Bind Cysteine Desulfurase and Donate Electrons for Iron–Sulfur Cluster Biosynthesis
Kai Cai, Marco Tonelli, Ronnie O. Frederick, John L. Markley
Biochemistry. 2017 Jan 24; 56(3): 487–499. Published online 2016 Dec 21. doi: 10.1021/acs.biochem.6b00447
PMCID:
PMC5267338
AbstractArticlePDF–5.1M
12.
Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery
Oleksandr Gakh, Wasantha Ranatunga, Douglas Y. Smith, IV, Eva-Christina Ahlgren, Salam Al-Karadaghi, James R. Thompson, Grazia Isaya
J Biol Chem. 2016 Sep 30; 291(40): 21296–21321. Published online 2016 Aug 12. doi: 10.1074/jbc.M116.738542
PMCID:
PMC5076535
AbstractArticlePDF–11M
13.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
14.
Deleterious mutation in FDX1L gene is associated with a novel mitochondrial muscle myopathy
Ronen Spiegel, Ann Saada, Jonatan Halvardson, Devorah Soiferman, Avraham Shaag, Simon Edvardson, Yoseph Horovitz, Morad Khayat, Stavit A Shalev, Lars Feuk, Orly Elpeleg
Eur J Hum Genet. 2014 Jul; 22(7): 902–906. Published online 2013 Nov 27. doi: 10.1038/ejhg.2013.269
PMCID:
PMC4060119
AbstractArticlePDF–659K
15.
Human Ferredoxin-2 Displays a Unique Conformational Change
Wenbin Qi, Jingwei Li, J. A. Cowan
Dalton Trans. Author manuscript; available in PMC 2014 Mar 7.
Published in final edited form as: Dalton Trans. 2013 Mar 7; 42(9): 3088–3091. Published online 2012 Dec 3. doi: 10.1039/c2dt32018e
PMCID:
PMC3622203
AbstractArticlePDF–1.7M
16.
Both human ferredoxins 1 and 2 and ferredoxin reductase are important for iron-sulfur cluster biogenesis
Yanbo Shi, Manik Ghosh, Gennadiy Kovtunovych, Daniel R. Crooks, Tracey A. Rouault
Biochim Biophys Acta. Author manuscript; available in PMC 2013 Jan 16.
Published in final edited form as: Biochim Biophys Acta. 2012 Feb; 1823(2): 484–492. Published online 2011 Nov 10. doi: 10.1016/j.bbamcr.2011.11.002
PMCID:
PMC3546607
AbstractArticlePDF–2.5M
17.
Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN
Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi
J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907
PMCID:
PMC3190826
AbstractArticlePDF–5.7M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Genetic Variants in Nuclear-Encoded Mitochondrial Genes Influence AIDS Progression
Sher L. Hendrickson, James A. Lautenberger, Leslie Wei Chinn, Michael Malasky, Efe Sezgin, Lawrence A. Kingsley, James J. Goedert, Gregory D. Kirk, Edward D. Gomperts, Susan P. Buchbinder, Jennifer L. Troyer, Stephen J. O'Brien
PLoS One. 2010; 5(9): e12862. Published online 2010 Sep 21. doi: 10.1371/journal.pone.0012862
PMCID:
PMC2943476
AbstractArticlePDF–461K
20.
Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis
Alex D. Sheftel, Oliver Stehling, Antonio J. Pierik, Hans-Peter Elsässer, Ulrich Mühlenhoff, Holger Webert, Anna Hobler, Frank Hannemann, Rita Bernhardt, Roland Lill
Proc Natl Acad Sci U S A. 2010 Jun 29; 107(26): 11775–11780. Published online 2010 Jun 14. doi: 10.1073/pnas.1004250107
PMCID:
PMC2900682
AbstractArticlePDF–1.2M

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