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Items: 1 to 20 of 30

1.
Craniofacial studies in chicken embryos confirm the pathogenicity of human FZD2 variants associated with Robinow syndrome
Shruti S. Tophkhane, Katherine Fu, Esther M. Verheyen, Joy M. Richman
Dis Model Mech. 2024 Jun 1; 17(6): dmm050584. Published online 2024 Jul 5. doi: 10.1242/dmm.050584
PMCID:
PMC11247504
AbstractArticle
2.
A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins
Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux
Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611
PMCID:
PMC8951556
AbstractArticlePDF–4.4M
3.
Integrated weighted gene coexpression network analysis identifies Frizzled 2 (FZD2) as a key gene in invasive malignant pleomorphic adenoma
Zhenyuan Han, Huiping Ren, Jingjing Sun, Lihui Jin, Qin Wang, Chuanbin Guo, Zhen Tian
J Transl Med. 2022; 20: 15. Published online 2022 Jan 5. doi: 10.1186/s12967-021-03204-7
PMCID:
PMC8734245
AbstractArticlePDF–6.1M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability
Divya Achuthankutty, Roshan Singh Thakur, Peter Haahr, Saskia Hoffmann, Alexandros P. Drainas, Anna H. Bizard, Joachim Weischenfeldt, Ian D. Hickson, Niels Mailand
J Cell Biol. 2019 Dec 2; 218(12): 3943–3953. Published online 2019 Oct 15. doi: 10.1083/jcb.201905064
PMCID:
PMC6891097
AbstractArticlePDF–2.7M
6.
FZD2 regulates cell proliferation and invasion in tongue squamous cell carcinoma
Li Huang, Er-Ling Luo, Jing Xie, Rui-Huan Gan, Lin-Can Ding, Bo-Hua Su, Yong Zhao, Li-Song Lin, Da-Li Zheng, You-Guang Lu
Int J Biol Sci. 2019; 15(11): 2330–2339. Published online 2019 Aug 24. doi: 10.7150/ijbs.33881
PMCID:
PMC6775310
AbstractArticlePDF–1.8M
7.
Frizzled 2‐induced epithelial‐mesenchymal transition correlates with vasculogenic mimicry, stemness, and Hippo signaling in hepatocellular carcinoma
Huohui Ou, Zhanjun Chen, Leyang Xiang, Yinghao Fang, Yuyan Xu, Qin Liu, Zhigang Hu, Xianghong Li, Yu Huang, Dinghua Yang
Cancer Sci. 2019 Apr; 110(4): 1169–1182. Published online 2019 Mar 6. doi: 10.1111/cas.13949
PMCID:
PMC6447835
AbstractArticlePDF–1.7M
8.
Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B
Peng Chen, Liang Tao, Tianyu Wang, Jie Zhang, Aina He, Kwok-ho Lam, Zheng Liu, Xi He, Kay Perry, Min Dong, Rongsheng Jin
Science. Author manuscript; available in PMC 2019 May 11.
Published in final edited form as: Science. 2018 May 11; 360(6389): 664–669. doi: 10.1126/science.aar1999
PMCID:
PMC6231499
AbstractArticlePDF–2.3M
9.
WNT Signaling Perturbations Underlie the Genetic Heterogeneity of Robinow Syndrome
Janson J. White, Juliana F. Mazzeu, Zeynep Coban-Akdemir, Yavuz Bayram, Vahid Bahrambeigi, Alexander Hoischen, Bregje W.M. van Bon, Alper Gezdirici, Elif Yilmaz Gulec, Francis Ramond, Renaud Touraine, Julien Thevenon, Marwan Shinawi, Erin Beaver, Jennifer Heeley, Julie Hoover-Fong, Ceren D. Durmaz, Halil Gurhan Karabulut, Ebru Marzioglu-Ozdemir, Atilla Cayir, Mehmet B. Duz, Mehmet Seven, Susan Price, Barbara Merfort Ferreira, Angela M. Vianna-Morgante, Sian Ellard, Andrew Parrish, Karen Stals, Josue Flores-Daboub, Shalini N. Jhangiani, Richard A. Gibbs, Baylor-Hopkins Center for Mendelian Genomics, Han G. Brunner, V. Reid Sutton, James R. Lupski, Claudia M.B. Carvalho
Am J Hum Genet. 2018 Jan 4; 102(1): 27–43. Published online 2017 Dec 21. doi: 10.1016/j.ajhg.2017.10.002
PMCID:
PMC5777383
AbstractArticlePDF–1.4M
10.
Down-regulation of miR-30a-3p/5p promotes esophageal squamous cell carcinoma cell proliferation by activating the Wnt signaling pathway
Bo Qi, Yan Wang, Zhi-Jun Chen, Xiang-Nan Li, Yu Qi, Yang Yang, Guang-Hui Cui, Hai-Zhou Guo, Wei-Hao Li, Song Zhao
World J Gastroenterol. 2017 Dec 7; 23(45): 7965–7977. Published online 2017 Dec 7. doi: 10.3748/wjg.v23.i45.7965
PMCID:
PMC5725291
AbstractArticlePDF–1.5M
11.
Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families
Oksana Voloshanenko, Philipp Gmach, Jan Winter, Dominique Kranz, Michael Boutros
FASEB J. 2017 Nov; 31(11): 4832–4844. Published online 2017 Jul 21. doi: 10.1096/fj.201700144R
PMCID:
PMC5636703
AbstractArticle
12.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
13.
Frizzled are colonic epithelial receptors for Clostridium difficile toxin B
Liang Tao, Jie Zhang, Paul Meraner, Alessio Tovaglieri, Xiaoqian Wu, Ralf Gerhard, Xinjun Zhang, William B. Stallcup, Ji Miao, Xi He, Julian G. Hurdle, David T. Breault, Abraham L. Brass, Min Dong
Nature. Author manuscript; available in PMC 2017 Jul 20.
Published in final edited form as: Nature. 2016 Oct 20; 538(7625): 350–355. Published online 2016 Sep 28. doi: 10.1038/nature19799
PMCID:
PMC5519134
AbstractArticlePDF–4.1M
14.
Frizzled2 signaling regulates growth of high-risk neuroblastomas by interfering with β-catenin-dependent and β-catenin-independent signaling pathways
Karin Zins, Romana Schäfer, Patrick Paulus, Silvia Dobler, Nazak Fakhari, Mouldy Sioud, Seyedhossein Aharinejad, Dietmar Abraham
Oncotarget. 2016 Jul 19; 7(29): 46187–46202. Published online 2016 Jun 15. doi: 10.18632/oncotarget.10070
PMCID:
PMC5216790
AbstractArticlePDF–9.0M
15.
A mutation in FRIZZLED2 impairs Wnt signaling and causes autosomal dominant omodysplasia
Howard M. Saal, Cynthia A. Prows, Iris Guerreiro, Milene Donlin, Luke Knudson, Kristen L. Sund, Ching-Fang Chang, Samantha A. Brugmann, Rolf W. Stottmann
Hum Mol Genet. 2015 Jun 15; 24(12): 3399–3409. Published online 2015 Mar 10. doi: 10.1093/hmg/ddv088
PMCID:
PMC4834928
AbstractArticlePDF–645K
16.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
17.
miR-203 Inhibits Frizzled-2 Expression via CD82/KAI1 Expression in Human Lung Carcinoma Cells
Mariko Mine, Kojiro Yamaguchi, Tsuyoshi Sugiura, Satomi Chigita, Naoya Yoshihama, Rumi Yoshihama, Naomi Hiyake, Yosuke Kobayashi, Yoshihide Mori
PLoS One. 2015; 10(7): e0131350. Published online 2015 Jul 1. doi: 10.1371/journal.pone.0131350
PMCID:
PMC4488846
AbstractArticlePDF–3.4M
18.
A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis
Taranjit S. Gujral, Marina Chan, Leonid Peshkin, Peter K. Sorger, Marc W. Kirschner, Gavin MacBeath
Cell. Author manuscript; available in PMC 2015 Nov 6.
Published in final edited form as: Cell. 2014 Nov 6; 159(4): 844–856. doi: 10.1016/j.cell.2014.10.032
PMCID:
PMC4243058
AbstractArticlePDF–2.8M
19.
Interpreting cancer genomes using systematic host perturbations by tumour virus proteins
Orit Rozenblatt-Rosen, Rahul C. Deo, Megha Padi, Guillaume Adelmant, Michael A. Calderwood, Thomas Rolland, Miranda Grace, Amélie Dricot, Manor Askenazi, Maria Tavares, Sam Pevzner, Fieda Abderazzaq, Danielle Byrdsong, Anne-Ruxandra Carvunis, Alyce A. Chen, Jingwei Cheng, Mick Correll, Melissa Duarte, Changyu Fan, Mariet C. Feltkamp, Scott B. Ficarro, Rachel Franchi, Brijesh K. Garg, Natali Gulbahce, Tong Hao, Amy M. Holthaus, Robert James, Anna Korkhin, Larisa Litovchick, Jessica C. Mar, Theodore R. Pak, Sabrina Rabello, Renee Rubio, Yun Shen, Saurav Singh, Jennifer M. Spangle, Murat Tasan, Shelly Wanamaker, James T. Webber, Jennifer Roecklein-Canfield, Eric Johannsen, Albert-László Barabási, Rameen Beroukhim, Elliott Kieff, Michael E. Cusick, David E. Hill, Karl Münger, Jarrod A. Marto, John Quackenbush, Frederick P. Roth, James A. DeCaprio, Marc Vidal
Nature. Author manuscript; available in PMC 2013 Jan 26.
Published in final edited form as: Nature. 2012 Jul 26; 487(7408): 491–495. doi: 10.1038/nature11288
PMCID:
PMC3408847
AbstractArticlePDF–937K
20.
Analysis of the myosinII-responsive focal adhesion proteome reveals a role for ß-Pix in negative regulation of focal adhesion maturation
Jean-Cheng Kuo, Xuemei Han, Cheng-Te Hsiao, John R. Yates, III, Clare M. Waterman
Nat Cell Biol. Author manuscript; available in PMC 2012 Feb 14.
Published in final edited form as: Nat Cell Biol. 2011 Apr; 13(4): 383–393. Published online 2011 Mar 20. doi: 10.1038/ncb2216
PMCID:
PMC3279191
AbstractArticlePDF–2.8M

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