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Select item 111094831.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 109215812.

CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation

Yongxin Zhang, Xiaofeng Wang, Wenwei Liu, Tianxiang Lei, Tang Qiao, Wei Feng, Wu Song

J Transl Med. 2024; 22: 251. Published online 2024 Mar 8. doi: 10.1186/s12967-023-04625-2

PMCID:: PMC10921581

Abstract Article PDF–13M

Select item 107898273.

Pathogenic monoallelic variants in GLIS3 increase type 2 diabetes risk and identify a subgroup of patients sensitive to sulfonylureas

Sarah Meulebrouck, Victoria Scherrer, Raphaël Boutry, Bénédicte Toussaint, Emmanuel Vaillant, Aurélie Dechaume, Hélène Loiselle, Beverley Balkau, Guillaume Charpentier, Sylvia Franc, Michel Marre, Morgane Baron, Martine Vaxillaire, Mehdi Derhourhi, Mathilde Boissel, Philippe Froguel, Amélie Bonnefond

Diabetologia. 2024; 67(2): 327–332. Published online 2023 Dec 5. doi: 10.1007/s00125-023-06035-x

PMCID:: PMC10789827

Abstract Article PDF–1.1M

Select item 103338844.

Large‐scale phosphomimetic screening identifies phospho‐modulated motif‐based protein interactions

Johanna Kliche, Dimitriya Hristoforova Garvanska, Leandro Simonetti, Dilip Badgujar, Doreen Dobritzsch, Jakob Nilsson, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2023 Jul; 19(7): e11164. Published online 2023 May 23. doi: 10.15252/msb.202211164

PMCID:: PMC10333884

Abstract Article PDF–5.0M

Select item 94792685.

A circular RNA derived from GLIS3 accelerates the proliferation of glioblastoma cells through competitively binding with miR-449c-5p to upregulate CAPG and GLIS3

Qingjiu Zhou, Mahati Shaya, Yalikun Kugeluke, Qiang Fu, Shaoshan Li, Yisireyili Dilimulati

BMC Neurosci. 2022; 23: 53. Published online 2022 Sep 16. doi: 10.1186/s12868-022-00736-6

PMCID:: PMC9479268

Abstract Article PDF–7.2M

Select item 87690726.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

Select item 87005247.

GLIS3: A Critical Transcription Factor in Islet β-Cell Generation

David W. Scoville, Anton M. Jetten

Cells. 2021 Dec; 10(12): 3471. Published online 2021 Dec 9. doi: 10.3390/cells10123471

PMCID:: PMC8700524

Abstract Article PDF–931K

Select item 81699768.

Case Report: Neonatal Diabetes Mellitus Caused by a Novel GLIS3 Mutation in Twins

Shira London, Elisa De Franco, Ghadir Elias-Assad, Marie Noufi Barhoum, Clari Felszer, Marina Paniakov, Scott A. Weiner, Yardena Tenenbaum-Rakover

Front Endocrinol (Lausanne) 2021; 12: 673755. Published online 2021 May 18. doi: 10.3389/fendo.2021.673755

PMCID:: PMC8169976

Abstract Article PDF–848K

Select item 80521869.

Neonatal diabetes mutations disrupt a chromatin pioneering function that activates the human insulin gene

Ildem Akerman, Miguel Angel Maestro, Elisa De Franco, Vanessa Grau, Sarah Flanagan, Javier García-Hurtado, Gerhard Mittler, Philippe Ravassard, Lorenzo Piemonti, Sian Ellard, Andrew T. Hattersley, Jorge Ferrer

Cell Rep. 2021 Apr 13; 35(2): 108981. Published online 2021 Apr 13. doi: 10.1016/j.celrep.2021.108981

PMCID:: PMC8052186

Abstract Article

Select item 767912110.

Oncogenic properties and signaling basis of the PAX8-GLIS3 fusion gene

Thais Basili, Higinio Dopeso, Sarah H. Kim, Lorenzo Ferrando, Fresia Pareja, Arnaud Da Cruz Paula, Edaise M. da Silva, Anthe Stylianou, Ana Maroldi, Caterina Marchiò, Brian P. Rubin, Mauro Papotti, Britta Weigelt, Carlos Gil Moreira Ferreira, José Roberto Lapa e Silva, Jorge S. Reis-Filho

Int J Cancer. Author manuscript; available in PMC 2021 Oct 15.

Published in final edited form as: Int J Cancer. 2020 Oct 15; 147(8): 2253–2264. Published online 2020 May 21. doi: 10.1002/ijc.33040

PMCID:: PMC7679121

Abstract Article PDF–2.1M

Select item 760655011.

Transcription factor GLIS3: critical roles in thyroid hormone biosynthesis, hypothyroidism, pancreatic beta cells and diabetes

David W. Scoville, Hong Soon Kang, Anton M. Jetten

Pharmacol Ther. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Pharmacol Ther. 2020 Nov; 215: 107632. Published online 2020 Jul 18. doi: 10.1016/j.pharmthera.2020.107632

PMCID:: PMC7606550

Abstract Article PDF–1.7M

Select item 744203512.

PAX8-GLIS3 gene fusion is a pathognomonic genetic alteration of hyalinizing trabecular tumors of the thyroid

Caterina Marchiò, Arnaud Da Cruz Paula, Rodrigo Gularte-Merida, Thais Basili, Alissa Brandes, Edaise M. da Silva, Catarina Silveira, Lorenzo Ferrando, Jasna Metovic, Francesca Maletta, Laura Annaratone, Fresia Pareja, Brian P. Rubin, Aaron P. Hoschar, Giovanni De Rosa, Stefano La Rosa, Massimo Bongiovanni, Bibianna Purgina, Simonetta Piana, Marco Volante, Britta Weigelt, Jorge S. Reis-Filho, Mauro Papotti

Mod Pathol. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Mod Pathol. 2019 Dec; 32(12): 1734–1743. Published online 2019 Jul 4. doi: 10.1038/s41379-019-0313-x

PMCID:: PMC7442035

Abstract Article PDF–2.3M

Select item 732206713.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 729072114.

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation

Danielle G. May, Kelsey L. Scott, Alexandre R. Campos, Kyle J. Roux

Cells. 2020 May; 9(5): 1070. Published online 2020 Apr 25. doi: 10.3390/cells9051070

PMCID:: PMC7290721

Abstract Article PDF–9.2M

Select item 716998315.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 669510216.

Sequencing reveals protective and pathogenic effects on development of diabetes of rare GLIS3 variants

Jihua Sun, Christian Theil Have, Mette Hollensted, Niels Grarup, Allan Linneberg, Oluf Pedersen, Jens Steen Nielsen, Jørgen Rungby, Cramer Christensen, Ivan Brandslund, Karsten Kristiansen, Wang Jun, Torben Hansen, Anette P. Gjesing

PLoS One. 2019; 14(8): e0220805. Published online 2019 Aug 15. doi: 10.1371/journal.pone.0220805

PMCID:: PMC6695102

Abstract Article PDF–494K

Select item 638977317.

GLIS Rearrangement is a Genomic Hallmark of Hyalinizing Trabecular Tumor of the Thyroid Gland

Marina N. Nikiforova, Alyaksandr V. Nikitski, Federica Panebianco, Cihan Kaya, Linwah Yip, Michelle Williams, Simion I. Chiosea, Raja R. Seethala, Somak Roy, Vincenzo Condello, Lucas Santana-Santos, Abigail I. Wald, Sally E. Carty, Robert L. Ferris, Adel K. El-Naggar, Yuri E. Nikiforov

Thyroid. 2019 Feb 1; 29(2): 161–173. Published online 2019 Feb 11. doi: 10.1089/thy.2018.0791

PMCID:: PMC6389773

Abstract Article PDF–1.8M

Select item 636887618.

GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells into Posterior Neural Progenitors

Kilsoo Jeon, Dhirendra Kumar, Amanda E. Conway, Kyeyoon Park, Raja Jothi, Anton M. Jetten

Stem Cells. Author manuscript; available in PMC 2020 Feb 1.

Published in final edited form as: Stem Cells. 2019 Feb; 37(2): 202–215. Published online 2018 Dec 2. doi: 10.1002/stem.2941

PMCID:: PMC6368876

Abstract Article PDF–3.5M

Select item 621979519.

Genotype-ocular biometry correlation analysis of eight primary angle closure glaucoma susceptibility loci in a cohort from Northern China

Wenjuan Zhuang, Shaolin Wang, Juan Hao, Manyun Xu, Hao Chi, Shunyu Piao, Jianqing Ma, Xiaolong Zhang, Shaoping Ha

PLoS One. 2018; 13(11): e0206935. Published online 2018 Nov 6. doi: 10.1371/journal.pone.0206935

PMCID:: PMC6219795

Abstract Article PDF–1.6M

Select item 615500020.

Discovering human diabetes-risk gene function with genetics and physiological assays

Heshan Peiris, Sangbin Park, Shreya Louis, Xueying Gu, Jonathan Y. Lam, Olof Asplund, Gregory C. Ippolito, Rita Bottino, Leif Groop, Haley Tucker, Seung K. Kim

Nat Commun. 2018; 9: 3855. Published online 2018 Sep 21. doi: 10.1038/s41467-018-06249-3

PMCID:: PMC6155000

Abstract Article PDF–2.2M

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