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Select item 112194371.

Asymmetric post-translational modifications regulate the nuclear translocation of STAT3 homodimers in response to leukemia inhibitory factor

Mickael Diallo, Constança Pimenta, Fernanda Murtinheira, Daniela Martins-Alves, Francisco R. Pinto, André Abrantes da Costa, Ricardo Letra-Vilela, Vanesa Martin, Carmen Rodriguez, Mário S. Rodrigues, Federico Herrera

Cell Oncol (Dordr) 2024; 47(3): 1065–1070. Published online 2023 Dec 27. doi: 10.1007/s13402-023-00911-9

PMCID:: PMC11219437

Abstract Article PDF–1.0M

Select item 110909362.

The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer

Cristina Di Giorgio, Rachele Bellini, Antonio Lupia, Carmen Massa, Ginevra Urbani, Martina Bordoni, Silvia Marchianò, Rosalinda Rosselli, Rosa De Gregorio, Pasquale Rapacciuolo, Valentina Sepe, Elva Morretta, Maria Chiara Monti, Federica Moraca, Luigi Cari, Khan Rana Sami Ullah, Nicola Natalizi, Luigina Graziosi, Eleonora Distrutti, Michele Biagioli, Bruno Catalanotti, Annibale Donini, Angela Zampella, Stefano Fiorucci

Cell Oncol (Dordr) 2024; 47(2): 695–710. Published online 2023 Nov 9. doi: 10.1007/s13402-023-00893-8

PMCID:: PMC11090936

Abstract Article PDF–13M

Select item 97934233.

The Pleiotropic role, functions and targeted therapies of LIF/LIFR axis in cancer: Old spectacles with new insights

Sushanta Halder, Seema Parte, Prakash Kshirsagar, Sakthivel Muniyan, Hareesh B. Nair, Surinder K. Batra, Parthasarathy Seshacharyulu

Biochim Biophys Acta Rev Cancer. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: Biochim Biophys Acta Rev Cancer. 2022 Jul; 1877(4): 188737. Published online 2022 Jun 6. doi: 10.1016/j.bbcan.2022.188737

PMCID:: PMC9793423

Abstract Article PDF–2.0M

Select item 88887534.

PCK1 regulates neuroendocrine differentiation in a positive feedback loop of LIF/ZBTB46 signalling in castration-resistant prostate cancer

Yu-Ching Wen, Chien-Liang Liu, Hsiu-Lien Yeh, Wei-Hao Chen, Kuo-Ching Jiang, Van Thi Ngoc Tram, Michael Hsiao, Jiaoti Huang, Wei-Yu Chen, Yen-Nien Liu

Br J Cancer. 2022 Mar 23; 126(5): 778–790. Published online 2021 Nov 24. doi: 10.1038/s41416-021-01631-3

PMCID:: PMC8888753

Abstract Article PDF–3.2M

Select item 87442115.

Endometrial injury concurrent with hysteroscopy increases the expression of Leukaemia inhibitory factor: a preliminary study

Suat Suphan Ersahin, Aynur Ersahin

Reprod Biol Endocrinol. 2022; 20: 11. Published online 2022 Jan 10. doi: 10.1186/s12958-021-00877-z

PMCID:: PMC8744211

Abstract Article PDF–685K

Select item 87430006.

Myeloid cell-mediated targeting of LIF to dystrophic muscle causes transient increases in muscle fiber lesions by disrupting the recruitment and dispersion of macrophages in muscle

Ivan Flores, Steven S Welc, Michelle Wehling-Henricks, James G Tidball

Hum Mol Genet. 2022 Jan 15; 31(2): 189–206. Published online 2021 Aug 14. doi: 10.1093/hmg/ddab230

PMCID:: PMC8743000

Abstract Article PDF–2.3M

Select item 83498787.

Mutant KRAS Downregulates the Receptor for Leukemia Inhibitory Factor (LIF) to Enhance a Signature of Glycolysis in Pancreatic Cancer and Lung Cancer

Suhu Liu, Helen I. Gandler, Isidora Tošić, Darwin Q. Ye, Zachary T. Giaccone, David A. Frank

Mol Cancer Res. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Mol Cancer Res. 2021 Aug; 19(8): 1283–1295. Published online 2021 Apr 30. doi: 10.1158/1541-7786.MCR-20-0633

PMCID:: PMC8349878

Abstract Article PDF–1.6M

Select item 81974178.

Induced Pluripotent Stem Cell-Derived Conditioned Medium Promotes Endogenous Leukemia Inhibitory Factor to Attenuate Endotoxin-Induced Acute Lung Injury

Vincent Yi-Fong Su, Shih-Hwa Chiou, Wei-Chih Chen, Wen-Kuang Yu, Huai-Hsuan Wu, Hao Chen, Kuang-Yao Yang

Int J Mol Sci. 2021 Jun; 22(11): 5554. Published online 2021 May 24. doi: 10.3390/ijms22115554

PMCID:: PMC8197417

Abstract Article PDF–5.4M

Select item 78411999.

Leukemia Inhibitory Factor Promotes Aggressiveness of Chordoma

Sukru Gulluoglu, Mesut Sahin, Emre Can Tuysuz, Cumhur Kaan Yaltirik, Aysegul Kuskucu, Ferda Ozkan, Fikrettin Sahin, Ugur Ture, Omer Faruk Bayrak

Oncol Res. 2017; 25(7): 1177–1188. Published online 2017 Aug 7. doi: 10.3727/096504017X14874349473815

PMCID:: PMC7841199

Abstract Article PDF–31M

Select item 716998310.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 704648211.

Retinal blood vessel‐origin yes‐associated protein (YAP) governs astrocytic maturation via leukaemia inhibitory factor (LIF)

Li‐Qian‐Yu Ai, Rong‐Di Yuan, Xi Chen, Yun‐Jia Liu, Wen‐Yi Liu, Jing‐Yi Zhu, Zhou Zhang, Jun Yan, Chun‐Lin Chen, Sen Lin, Jian Ye

Cell Prolif. 2020 Feb; 53(2): e12757. Published online 2020 Jan 8. doi: 10.1111/cpr.12757

PMCID:: PMC7046482

Abstract Article PDF–2.3M

Select item 662426012.

Blockade of leukemia inhibitory factor as a therapeutic approach to KRAS driven pancreatic cancer

Man-Tzu Wang, Nicole Fer, Jacqueline Galeas, Eric A. Collisson, Sung Eun Kim, Jeremy Sharib, Frank McCormick

Nat Commun. 2019; 10: 3055. Published online 2019 Jul 11. doi: 10.1038/s41467-019-11044-9

PMCID:: PMC6624260

Abstract Article PDF–1.5M

Select item 656537013.

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

Yu Shi, Weina Gao, Nikki K. Lytle, Peiwu Huang, Xiao Yuan, Amanda M. Dann, Maya Ridinger-Saison, Kathleen E. DelGiorno, Corina E. Antal, Gaoyang Liang, Annette R. Atkins, Galina Erikson, Huaiyu Sun, Jill Meisenhelder, Elena Terenziani, Gyunghwi Woo, Linjing Fang, Thom P. Santisakultarm, Uri Manor, Ruilian Xu, Carlos R. Becerra, Erkut Borazanci, Daniel D. Von Hoff, Paul M. Grandgenett, Michael A. Hollingsworth, Mathias Leblanc, Sarah E. Umetsu, Eric A. Collisson, Miriam Scadeng, Andrew M. Lowy, Timothy R. Donahue, Tannishtha Reya, Michael Downes, Ronald M. Evans, Geoffrey M. Wahl, Tony Pawson, Ruijun Tian, Tony Hunter

Nature. Author manuscript; available in PMC 2019 Oct 17.

Published in final edited form as: Nature. 2019 May; 569(7754): 131–135. Published online 2019 Apr 17. doi: 10.1038/s41586-019-1130-6

Correction in:: Nature. 2021 Nov 30

PMCID:: PMC6565370

Abstract Article PDF–6.7M

Select item 639208914.

Expression and effects of leukemia inhibitory factor on nucleus pulposus degeneration

Qiang Xiao, Ji-Huan Zeng, Hao Zhou, Quan-He Qiu, Bo Ke, Liang Deng, Zhen-Ming Hu, Jeffrey Roh, Min Dai

Mol Med Rep. 2019 Mar; 19(3): 2377–2385. Published online 2019 Jan 17. doi: 10.3892/mmr.2019.9874

PMCID:: PMC6392089

Abstract Article PDF–1.9M

Select item 637418615.

Leukemia Inhibitory Factor Functions in Parallel with Interleukin-6 to Promote Ovarian Cancer Growth

Karen McLean, Lijun Tan, Danielle E. Bolland, Lan G. Coffman, Luke F. Peterson, Moshe Talpaz, Nouri Neamati, Ronald J. Buckanovich

Oncogene. Author manuscript; available in PMC 2019 Apr 10.

Published in final edited form as: Oncogene. 2019 Feb; 38(9): 1576–1584. Published online 2018 Oct 10. doi: 10.1038/s41388-018-0523-6

PMCID:: PMC6374186

Abstract Article PDF–1.6M

Select item 581024416.

Effect of leukocyte inhibitory factor on neuron differentiation from human induced pluripotent stem cell-derived neural precursor cells

Liping Xu, Jingyi Long, Chun Shi, Nianping Zhang, Ying Lv, Junda Feng, Aiguo Xuan, Xiaosong He, Qingqing Li, Yinshan Bai, Shanshan Liu, Dahong Long

Int J Mol Med. 2018 Apr; 41(4): 2037–2049. Published online 2018 Jan 23. doi: 10.3892/ijmm.2018.3418

PMCID:: PMC5810244

Abstract Article PDF–2.4M

Select item 545757917.

Activating transcription factor 3 promotes embryo attachment via up-regulation of leukemia inhibitory factor in vitro

Xi Cheng, Jingyu Liu, Huizhi Shan, Lihua Sun, Chenyang Huang, Qiang Yan, Ruiwei Jiang, Lijun Ding, Yue Jiang, Jianjun Zhou, Guijun Yan, Haixiang Sun

Reprod Biol Endocrinol. 2017; 15: 42. Published online 2017 Jun 2. doi: 10.1186/s12958-017-0260-7

PMCID:: PMC5457579

Abstract Article PDF–3.7M

Select item 542790018.

ZEB1 regulates glioma stemness through LIF repression

Lincoln A. Edwards, Aiguo Li, Dror Berel, Mecca Madany, Nam-Ho Kim, Minzhi Liu, Mitch Hymowitz, Benjamin Uy, Rachel Jung, Minlin Xu, Keith L. Black, Altan Rentsendorj, Xuemo Fan, Wei Zhang, John S. Yu

Sci Rep. 2017; 7: 69. Published online 2017 Feb 28. doi: 10.1038/s41598-017-00106-x

PMCID:: PMC5427900

Abstract Article PDF–2.0M

Select item 490921419.

Integrative Analyses of Uterine Transcriptome and MicroRNAome Reveal Compromised LIF-STAT3 Signaling and Progesterone Response in the Endometrium of Patients with Recurrent/Repeated Implantation Failure (RIF)

Youngsok Choi, Hye-Ryun Kim, Eun Jin Lim, Miseon Park, Jung Ah Yoon, Yeon Sun Kim, Eun-Kyung Kim, Ji-Eun Shin, Ji Hyang Kim, Hwang Kwon, Haengseok Song, Dong-Hee Choi

PLoS One. 2016; 11(6): e0157696. Published online 2016 Jun 15. doi: 10.1371/journal.pone.0157696

PMCID:: PMC4909214

Abstract Article PDF–2.2M

Select item 486916920.

MLL1 and MLL1 fusion proteins have distinct functions in regulating leukemic transcription program

Jing Xu, Li Li, Jie Xiong, Aaron denDekker, Andrew Ye, Hacer Karatas, Liu Liu, He Wang, Zhaohui S Qin, Shaomeng Wang, Yali Dou

Cell Discov. 2016; 2: 16008. Published online 2016 May 17. doi: 10.1038/celldisc.2016.8

PMCID:: PMC4869169

Abstract Article PDF–2.0M

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