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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 103904922.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 99382163.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Abstract Article PDF–5.3M

Select item 98033604.

Tbx2 is a master regulator of inner versus outer hair cell differentiation

Jaime García-Añoveros, John C. Clancy, Chuan Zhi Foo, Ignacio García-Gómez, Yingjie Zhou, Kazuaki Homma, Mary Ann Cheatham, Anne Duggan

Nature. Author manuscript; available in PMC 2022 Dec 30.

Published in final edited form as: Nature. 2022 May; 605(7909): 298–303. Published online 2022 May 4. doi: 10.1038/s41586-022-04668-3

PMCID:: PMC9803360

Abstract Article PDF–4.3M

Select item 96038605.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 94819336.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 90145597.

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat

Nature. Author manuscript; available in PMC 2022 Apr 18.

Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2

PMCID:: PMC9014559

Abstract Article PDF–6.6M

Select item 83905178.

SRC3 acetylates calmodulin in the mouse brain to regulate synaptic plasticity and fear learning

Hai-Long Zhang, Wei Han, Yin-Quan Du, Bing Zhao, Pin Yang, Dong-Min Yin

J Biol Chem. 2021 Sep; 297(3): 101044. Published online 2021 Aug 4. doi: 10.1016/j.jbc.2021.101044

PMCID:: PMC8390517

Abstract Article PDF–2.7M

Select item 83831149.

Acetylation of calmodulin regulates synaptic plasticity and fear learning

Hai-Long Zhang, Bing Zhao, Wei Han, Yi-Bei Sun, Pin Yang, Yongjun Chen, Duan Ni, Jian Zhang, Dong-Min Yin

J Biol Chem. 2021 Sep; 297(3): 101034. Published online 2021 Jul 31. doi: 10.1016/j.jbc.2021.101034

PMCID:: PMC8383114

Abstract Article PDF–3.4M

Select item 801271010.

Enhancing calmodulin binding to ryanodine receptor is crucial to limit neuronal cell loss in Alzheimer disease

Yoshihide Nakamura, Takeshi Yamamoto, Xiaojuan Xu, Shigeki Kobayashi, Shinji Tanaka, Masaki Tamitani, Takashi Saito, Takaomi C. Saido, Masafumi Yano

Sci Rep. 2021; 11: 7289. Published online 2021 Mar 31. doi: 10.1038/s41598-021-86822-x

PMCID:: PMC8012710

Abstract Article PDF–4.5M

Select item 794908511.

Calmodulin binds and modulates K⁺-dependent Na⁺/Ca²⁺-exchanger isoform 4, NCKX4

Stephanie Thibodeau, Weidong Yang, Sunita Sharma, Jonathan Lytton

J Biol Chem. 2021 Jan-Jun; 296: 100092. Published online 2020 Nov 23. doi: 10.1074/jbc.RA120.015037

PMCID:: PMC7949085

Abstract Article PDF–3.6M

Select item 786711812.

Complex Arrhythmia Syndrome in a Knock-In Mouse Model Carrier of the N98S Calm1 Mutation

Wen-Chin Tsai, Shuai Guo, Michael A. Olaopa, Loren J. Field, Jin Yang, Changyu Shen, Ching-Pin Chang, Peng-Sheng Chen, Michael Rubart

Circulation. Author manuscript; available in PMC 2021 Nov 17.

Published in final edited form as: Circulation. 2020 Nov 17; 142(20): 1937–1955. Published online 2020 Sep 15. doi: 10.1161/CIRCULATIONAHA.120.046450

PMCID:: PMC7867118

Abstract Article PDF–3.4M

Select item 779567913.

Calmodulin Supports TRPA1 Channel Association with Opioid Receptors and Glutamate NMDA Receptors in the Nervous Tissue

Elsa Cortés-Montero, María Rodríguez-Muñoz, M. Carmen Ruiz-Cantero, Enrique J. Cobos, Pilar Sánchez-Blázquez, Javier Garzón-Niño

Int J Mol Sci. 2021 Jan; 22(1): 229. Published online 2020 Dec 28. doi: 10.3390/ijms22010229

PMCID:: PMC7795679

Abstract Article PDF–1.9M

Select item 749801914.

The calmodulin redox sensor controls myogenesis

Alex W. Steil, Jacob W. Kailing, Cade J. Armstrong, Daniel G. Walgenbach, Jennifer C. Klein

PLoS One. 2020; 15(9): e0239047. Published online 2020 Sep 17. doi: 10.1371/journal.pone.0239047

PMCID:: PMC7498019

Abstract Article PDF–2.0M

Select item 749132715.

Elimination of Calm1 long 3′-UTR mRNA isoform by CRISPR–Cas9 gene editing impairs dorsal root ganglion development and hippocampal neuron activation in mice

Bongmin Bae, Hannah N. Gruner, Maebh Lynch, Ting Feng, Kevin So, Daniel Oliver, Grant S. Mastick, Wei Yan, Simon Pieraut, Pedro Miura

RNA. 2020 Oct; 26(10): 1414–1430. doi: 10.1261/rna.076430.120

PMCID:: PMC7491327

Abstract Article PDF–8.2M

Select item 688046416.

Protein Kinase C and Calmodulin Serve As Calcium Sensors for Calcium-Stimulated Endocytosis at Synapses

Ying-Hui Jin, Xin-Sheng Wu, Bo Shi, Zhen Zhang, Xiaoli Guo, Lin Gan, Zhongqing Chen, Ling-Gang Wu

J Neurosci. 2019 Nov 27; 39(48): 9478–9490. doi: 10.1523/JNEUROSCI.0182-19.2019

PMCID:: PMC6880464

Abstract Article PDF–2.8M

Select item 675807117.

Calmodulin Is an Auxiliary Subunit of KCNQ2/3 Potassium Channels

Hua Wen, Irwin B. Levitan

J Neurosci. 2002 Sep 15; 22(18): 7991–8001. doi: 10.1523/JNEUROSCI.22-18-07991.2002

PMCID:: PMC6758071

Abstract Article PDF–429K

Select item 665555118.

WDFY4 is required for cross-presentation in response to viral and tumor antigens

Derek J. Theisen, Jesse T. Davidson, IV, Carlos G. Briseño, Marco Gargaro, Elvin J. Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R. Brickner, Wandy L. Beatty, Herbert W. Virgin, William E. Gillanders, Nima Mosammaparast, Michael S. Diamond, L. David Sibley, Wayne Yokoyama, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy

Science. Author manuscript; available in PMC 2019 Jul 24.

Published in final edited form as: Science. 2018 Nov 9; 362(6415): 694–699. doi: 10.1126/science.aat5030

PMCID:: PMC6655551

Abstract Article PDF–1020K

Select item 664824019.

The Axonal Motor Neuropathy-Related HINT1 Protein Is a Zinc- and Calmodulin-Regulated Cysteine SUMO Protease

Elsa Cortés-Montero, María Rodríguez-Muñoz, Pilar Sánchez-Blázquez, Javier Garzón

Antioxid Redox Signal. 2019 Sep 1; 31(7): 503–520. Published online 2019 Jul 17. doi: 10.1089/ars.2019.7724

PMCID:: PMC6648240

Abstract Article PDF–1.8M

Select item 661835520.

Calcineurin Interacts with the Serotonin Transporter C-Terminus to Modulate Its Plasma Membrane Expression and Serotonin Uptake

Mathieu Seimandi, Pascal Seyer, C. Sehwan Park, Franck Vandermoere, Benjamin Chanrion, Joël Bockaert, Isabelle M. Mansuy, Philippe Marin

J Neurosci. 2013 Oct 9; 33(41): 16189–16199. doi: 10.1523/JNEUROSCI.0076-13.2013

PMCID:: PMC6618355

Abstract Article PDF–1.4M

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