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Items: 1 to 20 of 44

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Cleavage of the V-ATPase associated prorenin receptor is mediated by PACE4 and is essential for growth of prostate cancer cells
Amro H. Mohammad, Frédéric Couture, Isabelle Gamache, Owen Chen, Wissal El-Assaad, Nelly Abdel-Malak, Anna Kwiatkowska, William Muller, Robert Day, Jose G. Teodoro
PLoS One. 2023; 18(7): e0288622. Published online 2023 Jul 18. doi: 10.1371/journal.pone.0288622
PMCID:
PMC10353799
AbstractArticlePDF–3.3M
3.
PCSK6 mediates Th1 differentiation and promotes chronic colitis progression and mucosal barrier injury via STAT1
Xiaoping Mei, Hongkun Zhou, Zhengwei Song, Xiaodan Yang, Xiaorong Liu, Jianguo Fei, Yiyu Shen, Xiaoguang Wang
Aging (Albany NY) 2023 May 31; 15(10): 4363–4373. Published online 2023 May 20. doi: 10.18632/aging.204739
PMCID:
PMC10258034
AbstractArticlePDF–962K
4.
Proprotein Convertase Subtilisin/Kexin 6 in Cardiovascular Biology and Disease
Qingyu Wu, Shenghan Chen
Int J Mol Sci. 2022 Nov; 23(21): 13429. Published online 2022 Nov 3. doi: 10.3390/ijms232113429
PMCID:
PMC9656567
AbstractArticlePDF–823K
5.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
6.
Lack of PCSK6 Increases Flow-Mediated Outward Arterial Remodeling in Mice
Samuel Röhl, Bianca E. Suur, Mariette Lengquist, Till Seime, Kenneth Caidahl, Ulf Hedin, Anders Arner, Ljubica Matic, Anton Razuvaev
Cells. 2020 Apr; 9(4): 1009. Published online 2020 Apr 18. doi: 10.3390/cells9041009
PMCID:
PMC7225991
AbstractArticlePDF–2.4M
7.
Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse
Sebastian J. Arnold, Ulf K. Hofmann, Elizabeth K. Bikoff, Elizabeth J. Robertson
Development. Author manuscript; available in PMC 2020 Nov 18.
Published in final edited form as: Development. 2008 Feb 1; 135(3): 501–11. Published online 2008 Jan 2. doi: 10.1242/dev.014357
PMCID:
PMC7116389
AbstractArticlePDF–2.8M
8.
A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis
Matthew R. Jones, Salma Dilai, Arun Lingampally, Cho-Ming Chao, Soula Danopoulos, Gianni Carraro, Regina Mukhametshina, Jochen Wilhelm, Eveline Baumgart-Vogt, Denise Al Alam, Chengshui Chen, Parviz Minoo, Jin San Zhang, Saverio Bellusci
Front Genet. 2018; 9: 746. Published online 2019 Jan 23. doi: 10.3389/fgene.2018.00746
PMCID:
PMC6351499
AbstractArticlePDF–5.6M
9.
A new mouse model of ARX dup24 recapitulates the patients’ behavioral and fine motor alterations
Aline Dubos, Hamid Meziane, Giovanni Iacono, Aurore Curie, Fabrice Riet, Christelle Martin, Nadège Loaëc, Marie-Christine Birling, Mohammed Selloum, Elisabeth Normand, Guillaume Pavlovic, Tania Sorg, Henk G Stunnenberg, Jamel Chelly, Yann Humeau, Gaëlle Friocourt, Yann Hérault
Hum Mol Genet. 2018 Jun 15; 27(12): 2138–2153. Published online 2018 Apr 5. doi: 10.1093/hmg/ddy122
PMCID:
PMC5985730
AbstractArticlePDF–1.5M
10.
The epigenetic modifier Fam208a is required to maintain epiblast cell fitness
Shohag Bhargava, Brian Cox, Christiana Polydorou, Veronika Gresakova, Vladimir Korinek, Hynek Strnad, Radislav Sedlacek, Trevor Allan Epp, Kallayanee Chawengsaksophak
Sci Rep. 2017; 7: 9322. Published online 2017 Aug 24. doi: 10.1038/s41598-017-09490-w
Correction in:
Sci Rep. 2018; 8: 5762.
PMCID:
PMC5570896
AbstractArticlePDF–7.4M
11.
Increased dosage of the imprinted Ascl2 gene restrains two key endocrine lineages of the mouse Placenta
S.J. Tunster, G.I. McNamara, H.D.J. Creeth, R.M. John
Dev Biol. 2016 Oct 1; 418(1): 55–65. doi: 10.1016/j.ydbio.2016.08.014
PMCID:
PMC5040514
AbstractArticle
12.
The ability of inner cell mass cells to self-renew as embryonic stem cells is acquired upon epiblast specification
Thorsten Boroviak, Remco Loos, Paul Bertone, Austin Smith, Jennifer Nichols
Nat Cell Biol. Author manuscript; available in PMC 2016 May 24.
Published in final edited form as: Nat Cell Biol. 2014 Jun; 16(6): 516–528. Published online 2014 May 25. doi: 10.1038/ncb2965
PMCID:
PMC4878656
AbstractArticlePDF–7.9M
13.
Gene network and familial analyses uncover a gene network involving Tbx5/Osr1/Pcsk6 interaction in the second heart field for atrial septation
Ke K. Zhang, Menglan Xiang, Lun Zhou, Jielin Liu, Nathan Curry, Damian Heine Suñer, Pablo Garcia-Pavia, Xiaohua Zhang, Qin Wang, Linglin Xie
Hum Mol Genet. 2016 Mar 15; 25(6): 1140–1151. Published online 2016 Jan 6. doi: 10.1093/hmg/ddv636
PMCID:
PMC4764195
AbstractArticlePDF–972K
14.
PCSK6-mediated corin activation is essential for normal blood pressure
Shenghan Chen, Pengxiu Cao, Ningzheng Dong, Jianhao Peng, Chunyi Zhang, Hao Wang, Tiantian Zhou, Junhua Yang, Yue Zhang, Elizabeth E Martelli, Sathyamangla V Naga Prasad, Rachel E Miller, Anne-Marie Malfait, Yiqing Zhou, Qingyu Wu
Nat Med. Author manuscript; available in PMC 2016 Sep 1.
Published in final edited form as: Nat Med. 2015 Sep; 21(9): 1048–1053. Published online 2015 Aug 10. doi: 10.1038/nm.3920
PMCID:
PMC4710517
AbstractArticlePDF–438K
15.
Collaborative cross mice in a genetic association study reveal new candidate genes for bone microarchitecture
Roei Levy, Richard F. Mott, Fuad A. Iraqi, Yankel Gabet
BMC Genomics. 2015; 16: 1013. Published online 2015 Nov 26. doi: 10.1186/s12864-015-2213-x
PMCID:
PMC4661944
AbstractArticlePDF–1.6M
16.
Global genetic analysis in mice unveils central role for cilia in congenital heart disease
You Li, Nikolai T. Klena, George C Gabriel, Xiaoqin Liu, Andrew J. Kim, Kristi Lemke, Yu Chen, Bishwanath Chatterjee, William Devine, Rama Rao Damerla, Chien-fu Chang, Hisato Yagi, Jovenal T. San Agustin, Mohamed Thahir, Shane Anderton, Caroline Lawhead, Anita Vescovi, Herbert Pratt, Judy Morgan, Leslie Haynes, Cynthia L. Smith, Janan T. Eppig, Laura Reinholdt, Richard Francis, Linda Leatherbury, Madhavi K. Ganapathiraju, Kimimasa Tobita, Gregory J. Pazour, Cecilia W. Lo
Nature. Author manuscript; available in PMC 2015 Nov 28.
Published in final edited form as: Nature. 2015 May 28; 521(7553): 520–524. Published online 2015 Mar 25. doi: 10.1038/nature14269
PMCID:
PMC4617540
AbstractArticlePDF–518K
17.
PC7 and the related proteases Furin and Pace4 regulate E-cadherin function during blastocyst formation
Sylvain Bessonnard, Daniel Mesnard, Daniel B. Constam
J Cell Biol. 2015 Sep 28; 210(7): 1185–1197. doi: 10.1083/jcb.201503042
PMCID:
PMC4586756
AbstractArticlePDF–6.1M
18.
Enhanced aggressiveness of benzopyrene-induced squamous carcinomas in transgenic mice overexpressing the proprotein convertase PACE4 (PCSK6)
Daniel E. Bassi, Jonathan Cenna, Jirong Zhang, Edna Cukierman, Andres J. Klein-Szanto
Mol Carcinog. Author manuscript; available in PMC 2016 Oct 1.
Published in final edited form as: Mol Carcinog. 2015 Oct; 54(10): 1122–1131. Published online 2014 May 21. doi: 10.1002/mc.22183
PMCID:
PMC4240754
AbstractArticlePDF–1.8M
19.
Furin Is the Primary in Vivo Convertase of Angiopoietin-like 3 and Endothelial Lipase in Hepatocytes
Rachid Essalmani, Delia Susan-Resiga, Ann Chamberland, Marie-Claude Asselin, Maryssa Canuel, Daniel Constam, John W. Creemers, Robert Day, Dany Gauthier, Annik Prat, Nabil G. Seidah
J Biol Chem. 2013 Sep 13; 288(37): 26410–26418. Published online 2013 Aug 5. doi: 10.1074/jbc.M113.501304
PMCID:
PMC3772187
AbstractArticlePDF–1.1M
20.
A Role for PACE4 in Osteoarthritis Pain: Evidence from Human Genetic Association and Null Mutant Phenotype
Anne-Marie Malfait, Albert B. Seymour, Feng Gao, Micky D. Tortorella, Marie-Pierre Hellio Le Graverand-Gastineau, Linda S. Wood, Michael Doherty, Sally Doherty, Weiya Zhang, Nigel K. Arden, Frances L. Vaughn, Paul L. Leaverton, Tim D. Spector, Deborah J. Hart, Rose A. Maciewicz, Kenneth R. Muir, Rosalina Das, Robert E. Sorge, Susanna G. Sotocinal, Ara Schorscher-Petcu, Ana M. Valdes, Jeffrey S. Mogil
Ann Rheum Dis. Author manuscript; available in PMC 2013 Jun 1.
Published in final edited form as: Ann Rheum Dis. 2012 Jun; 71(6): 1042–1048. Published online 2012 Mar 22. doi: 10.1136/annrheumdis-2011-200300
PMCID:
PMC3603144
AbstractArticlePDF–1.2M

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