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Select item 110146691.

Complement C3 and marginal zone B cells promote IgG-mediated enhancement of RBC alloimmunization in mice

Arijita Jash, Thomas Pridmore, James B. Collins, Ariel M. Hay, Krystalyn E. Hudson, Chance John Luckey, James C. Zimring

J Clin Invest. 2024 Apr 15; 134(8): e167665. Published online 2024 Apr 15. doi: 10.1172/JCI167665

PMCID:: PMC11014669

Abstract Article PDF–2.3M

Select item 108416672.

T cell-specific P2RX7 favors lung parenchymal CD4⁺ T cell accumulation in response to severe lung infections

Igor Santiago-Carvalho, Gislane Almeida-Santos, Bruna Gois Macedo, Caio Cesar Barbosa-Bomfim, Fabricio Moreira Almeida, Marcos Vinícios Pinheiro Cione, Trupti Vardam-Kaur, Mia Masuda, Sarah Van Dijk, Bruno Marcel Melo, Rogério Silva do Nascimento, Rebeka da Conceição Souza, Alba Lucínia Peixoto-Rangel, Robson Coutinho-Silva, Mario Hiroyuki Hirata, José Carlos Alves-Filho, José Maria Álvarez, Elena Lassounskaia, Henrique Borges da Silva, Maria Regina D’Império-Lima

Cell Rep. Author manuscript; available in PMC 2024 Feb 5.

Published in final edited form as: Cell Rep. 2023 Nov 28; 42(11): 113448. Published online 2023 Nov 15. doi: 10.1016/j.celrep.2023.113448

PMCID:: PMC10841667

Abstract Article PDF–3.2M

Select item 107925163.

ThPOK is a critical multifaceted regulator of myeloid lineage development

Jayati Basu, Andre Olsson, Kyle Ferchen, Elizaveta K. Titerina, Kashish Chetal, Emmanuelle Nicolas, Philip Czyzewicz, Dmitry Levchenko, Lu Ge, Xiang Hua, H. Leighton Grimes, Nathan Salomonis, Dietmar J. Kappes

Nat Immunol. Author manuscript; available in PMC 2024 Jan 17.

Published in final edited form as: Nat Immunol. 2023 Aug; 24(8): 1295–1307. Published online 2023 Jul 20. doi: 10.1038/s41590-023-01549-3

PMCID:: PMC10792516

Abstract Article PDF–6.7M

Select item 106767544.

Lung cDC1 and cDC2 dendritic cells priming naive CD8⁺ T cells in situ prior to migration to draining lymph nodes

Youhui Si, Yihan Wang, Qiaomu Tian, Qiang Wang, Jared M. Pollard, Pramod K. Srivastava, Aaron P. Esser-Kahn, Joel H. Collier, Anne I. Sperling, Anita S. Chong

Cell Rep. Author manuscript; available in PMC 2023 Nov 26.

Published in final edited form as: Cell Rep. 2023 Oct 31; 42(10): 113299. doi: 10.1016/j.celrep.2023.113299

PMCID:: PMC10676754

Abstract Article PDF–2.3M

Select item 105859195.

A Cryptosporidium parvum vaccine candidate effect on immunohistochemical profiling of CD4⁺, CD8⁺, Caspase-3 and NF-κB in mice

Dina Aboelsoued, Nagwa I. Toaleb, Sally Ibrahim, Raafat M. Shaapan, Kadria N. Abdel Megeed

BMC Vet Res. 2023; 19: 216. Published online 2023 Oct 19. doi: 10.1186/s12917-023-03699-w

PMCID:: PMC10585919

Abstract Article PDF–3.6M

Select item 105781416.

Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control

Mengdi Guo, Diala Abd-Rabbo, Bruna C. Bertol, Madeleine Carew, Sabelo Lukhele, Laura M. Snell, Wenxi Xu, Giselle M. Boukhaled, Heidi Elsaesser, Marie Jo Halaby, Naoto Hirano, Tracy L. McGaha, David G. Brooks

Cell Rep. Author manuscript; available in PMC 2023 Oct 16.

Published in final edited form as: Cell Rep. 2023 Sep 26; 42(9): 113047. Published online 2023 Aug 30. doi: 10.1016/j.celrep.2023.113047

PMCID:: PMC10578141

Abstract Article PDF–3.5M

Select item 105566687.

Antigen-driven T cell-macrophage interactions mediate the interface between innate and adaptive immunity in histidyl-tRNA synthetase-induced myositis

Daniel P. Reay, Tracy Tabib, Ying Wang, Timothy B. Oriss, Nicholas A. Young, Robert A. Lafyatis, Wael N. Jarjour, Paula R. Clemens, Dana P. Ascherman

Front Immunol. 2023; 14: 1238221. Published online 2023 Sep 22. doi: 10.3389/fimmu.2023.1238221

PMCID:: PMC10556668

Abstract Article PDF–9.6M

Select item 104804778.

Notch and retinoic acid signals regulate macrophage formation from endocardium downstream of Nkx2-5

Norika Liu, Naofumi Kawahira, Yasuhiro Nakashima, Haruko Nakano, Akiyasu Iwase, Yasunobu Uchijima, Mei Wang, Sean M. Wu, Susumu Minamisawa, Hiroki Kurihara, Atsushi Nakano

Nat Commun. 2023; 14: 5398. Published online 2023 Sep 5. doi: 10.1038/s41467-023-41039-6

PMCID:: PMC10480477

Abstract Article PDF–2.4M

Select item 101105019.

Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling

Dhwani N. Rupani, Fredrik I. Thege, Vidhi Chandra, Hajar Rajaei, Robert W. Cowan, Sonja M. Wörmann, Olivereen Le Roux, Prerna Malaney, Sara L. Manning, Jack Hashem, Jennifer Bailey-Lundberg, Andrew D. Rhim, Florencia McAllister

Development. 2023 Jan 15; 150(2): dev201097. Published online 2023 Jan 16. doi: 10.1242/dev.201097

PMCID:: PMC10110501

Abstract Article

Select item 1004077310.

P2RX7 signaling drives the differentiation of Th1 cells through metabolic reprogramming for aerobic glycolysis

Érika Machado de Salles, Paulo Lisboa Raeder, Claudia Blanes Angeli, Verônica Feijoli Santiago, Cristiane Naffah de Souza, Theresa Ramalho, Niels Olsen Saraiva Câmara, Giuseppe Palmisano, José Maria Álvarez, Maria Regina D'Império Lima

Front Immunol. 2023; 14: 1140426. Published online 2023 Mar 13. doi: 10.3389/fimmu.2023.1140426

PMCID:: PMC10040773

Abstract Article PDF–3.9M

Select item 987541911.

Transfer of mesenchymal stem cell mitochondria to CD4⁺ T cells contributes to repress Th1 differentiation by downregulating T-bet expression

Waseem Akhter, Jean Nakhle, Loïc Vaillant, Geneviève Garcin, Cécile Le Saout, Matthieu Simon, Carole Crozet, Farida Djouad, Christian Jorgensen, Marie-Luce Vignais, Javier Hernandez

Stem Cell Res Ther. 2023; 14: 12. Published online 2023 Jan 24. doi: 10.1186/s13287-022-03219-x

PMCID:: PMC9875419

Abstract Article PDF–1.3M

Select item 976094812.

Citrullinated glucose-regulated protein 78 is a candidate target for melanoma immunotherapy

Victoria Anne Brentville, Peter Symonds, JiaXin Chua, Anne Skinner, Ian Daniels, Katherine Wendy Cook, Sasa Koncarevic, Roxana Martinez-Pinna, Sabaria Shah, Ruhul Hasan Choudhury, Poonam Vaghela, Daisy Weston, Abdullah Al-Omari, James Davis, Lindy G. Durrant

Front Immunol. 2022; 13: 1066185. Published online 2022 Dec 5. doi: 10.3389/fimmu.2022.1066185

PMCID:: PMC9760948

Abstract Article PDF–2.4M

Select item 966588513.

Mapping Brain Gene Coexpression in Daytime Transcriptomes Unveils Diurnal Molecular Networks and Deciphers Perturbation Gene Signatures

Nan Wang, Peter Langfelder, Matthew Stricos, Lalini Ramanathan, Jeffrey B. Richman, Raymond Vaca, Mary Plascencia, Xiaofeng Gu, Shasha Zhang, T. Katherine Tamai, Liguo Zhang, Fuying Gao, Koliane Ouk, Xiang Lu, Leonya Ivanov, Tom Vogt, Qing Richard Lu, A. Jennifer Morton, Christopher Colwell, Jeffrey S. Aaronson, Jim Rosinski, Steve Horvath, X. William Yang

Neuron. Author manuscript; available in PMC 2023 Oct 19.

Published in final edited form as: Neuron. 2022 Oct 19; 110(20): 3318–3338.e9. doi: 10.1016/j.neuron.2022.09.028

PMCID:: PMC9665885

Abstract Article PDF–4.5M

Select item 961368414.

Targeting vasoactive intestinal peptide-mediated signaling enhances response to immune checkpoint therapy in pancreatic ductal adenocarcinoma

Sruthi Ravindranathan, Tenzin Passang, Jian-Ming Li, Shuhua Wang, Rohan Dhamsania, Michael Brandon Ware, Mohammad Y. Zaidi, Jingru Zhu, Maria Cardenas, Yuan Liu, Sanjeev Gumber, Brian Robinson, Anish Sen-Majumdar, Hanwen Zhang, Shanmuganathan Chandrakasan, Haydn Kissick, Alan B. Frey, Susan N. Thomas, Bassel F. El-Rayes, Gregory B. Lesinski, Edmund K. Waller

Nat Commun. 2022; 13: 6418. Published online 2022 Oct 27. doi: 10.1038/s41467-022-34242-4

PMCID:: PMC9613684

Abstract Article PDF–2.4M

Select item 948904315.

Induction of tumor cell autosis by myxoma virus-infected CAR-T and TCR-T cells to overcome primary and acquired resistance

Ningbo Zheng, Jing Fang, Gang Xue, Ziyu Wang, Xiaoyin Li, Mengshi Zhou, Guangxu Jin, Masmudur M. Rahman, Grant McFadden, Yong Lu

Cancer Cell. Author manuscript; available in PMC 2023 Sep 12.

Published in final edited form as: Cancer Cell. 2022 Sep 12; 40(9): 973–985.e7. Published online 2022 Aug 25. doi: 10.1016/j.ccell.2022.08.001

PMCID:: PMC9489043

Abstract Article PDF–3.1M

Select item 939232416.

Human induced pluripotent stem cell engineering establishes a humanized mouse platform for pediatric low-grade glioma modeling

Corina Anastasaki, Jit Chatterjee, Olivia Cobb, Shilpa Sanapala, Suzanne M. Scheaffer, Amanda De Andrade Costa, Anna F. Wilson, Chloe M. Kernan, Ameera H. Zafar, Xia Ge, Joel R. Garbow, Fausto J. Rodriguez, David H. Gutmann

Acta Neuropathol Commun. 2022; 10: 120. Published online 2022 Aug 19. doi: 10.1186/s40478-022-01428-2

PMCID:: PMC9392324

Abstract Article PDF–13M

Select item 935142417.

T Cell activation and IFNγ modulate organ dysfunction in lipopolysaccharide-mediated inflammation

Matthew D. Taylor, Tiago D. Fernandes, Omar Yaipen, Cassidy E. Higgins, Christine A. Capone, Daniel E. Leisman, Ana Nedeljkovic-Kurepa, Mabel N. Abraham, Mariana R. Brewer, Clifford S. Deutschman

J Leukoc Biol. Author manuscript; available in PMC 2023 Aug 1.

Published in final edited form as: J Leukoc Biol. 2022 Aug; 112(2): 221–232. Published online 2022 Feb 9. doi: 10.1002/JLB.4HI0921-492R

PMCID:: PMC9351424

Abstract Article PDF–2.5M

Select item 909838718.

Reversal of the T cell immune system reveals the molecular basis for T cell lineage fate determination in the thymus

Miho Shinzawa, E. Ashley Moseman, Selamawit Gossa, Yasuko Mano, Abhisek Bhattacharya, Terry Guinter, Amala Alag, Xiongfong Chen, Maggie Cam, Dorian B. McGavern, Batu Erman, Alfred Singer

Nat Immunol. 2022; 23(5): 731–742. Published online 2022 Apr 29. doi: 10.1038/s41590-022-01187-1

PMCID:: PMC9098387

Abstract Article PDF–13M

Select item 908116919.

Survival motor neuron protein deficiency alters microglia reactivity

Guzal Khayrullina, Zaida A. Alipio‐Gloria, Marc‐Olivier Deguise, Sabrina Gagnon, Lucia Chehade, Matthew Stinson, Natalya Belous, Elizabeth M. Bergman, Fritz W. Lischka, Jeremy Rotty, Clifton L. Dalgard, Rashmi Kothary, Kristen A. Johnson, Barrington G. Burnett

Glia. 2022 Jul; 70(7): 1337–1358. Published online 2022 Apr 4. doi: 10.1002/glia.24177

PMCID:: PMC9081169

Abstract Article PDF–21M

Select item 902876720.

Vaccine Can Induce CD4-Mediated Responses to Homocitrullinated Peptides via Multiple HLA-Types and Confer Anti-Tumor Immunity

Katherine Cook, Wei Xue, Suha Atabani, Peter Symonds, Abdullah Al Omari, Ian Daniels, Sabaria Shah, Ruhul Hasan Choudhury, Daisy Weston, Rachael Metheringham, Victoria Brentville, Lindy Durrant

Front Immunol. 2022; 13: 873947. Published online 2022 Apr 8. doi: 10.3389/fimmu.2022.873947

PMCID:: PMC9028767

Abstract Article PDF–7.3M

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