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Items: 1 to 20 of 29

1.
The guanine nucleotide exchange factor RapGEF2 is required for ERK-dependent immediate-early gene (Egr1) activation during fear memory formation
Sunny Zhihong Jiang, Meishar Shahoha, Hai-Ying Zhang, William Brancaleone, Abdel Elkahloun, Hugo A. Tejeda, Uri Ashery, Lee E. Eiden
Cell Mol Life Sci. 2024 Dec; 81(1): 48. Published online 2024 Jan 18. doi: 10.1007/s00018-023-04999-y
PMCID:
PMC11071968
AbstractArticlePDF–6.6M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
RAPGEF2 mediates oligomeric Aβ‐induced synaptic loss and cognitive dysfunction in the 3xTg‐AD mouse model of Alzheimer’s disease
You‐Na Jang, HoChung Jang, Gyu Hyun Kim, Jeong‐Eun Noh, Keun‐A Chang, Kea Joo Lee
Neuropathol Appl Neurobiol. 2021 Aug; 47(5): 625–639. Published online 2021 Jan 6. doi: 10.1111/nan.12686
PMCID:
PMC8359155
AbstractArticlePDF–1.9M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
5.
Cocaine-Dependent Acquisition of Locomotor Sensitization and Conditioned Place Preference Requires D1 Dopaminergic Signaling through a Cyclic AMP, NCS-Rapgef2, ERK, and Egr-1/Zif268 Pathway
Sunny Zhihong Jiang, Sean Sweat, Sam P. Dahlke, Kathleen Loane, Gunner Drossel, Wenqin Xu, Hugo A. Tejeda, Charles R. Gerfen, Lee E. Eiden
J Neurosci. 2021 Jan 27; 41(4): 711–725. doi: 10.1523/JNEUROSCI.1497-20.2020
PMCID:
PMC7842751
AbstractArticlePDF–6.8M
6.
DSCAM regulates delamination of neurons in the developing midbrain
Nariko Arimura, Mako Okada, Shinichiro Taya, Ken-ichi Dewa, Akiko Tsuzuki, Hirotomo Uetake, Satoshi Miyashita, Koichi Hashizume, Kazumi Shimaoka, Saki Egusa, Tomoki Nishioka, Yuchio Yanagawa, Kazuhiro Yamakawa, Yukiko U. Inoue, Takayoshi Inoue, Kozo Kaibuchi, Mikio Hoshino
Sci Adv. 2020 Sep; 6(36): eaba1693. Published online 2020 Sep 2. doi: 10.1126/sciadv.aba1693
PMCID:
PMC7467692
AbstractArticlePDF–3.1M
7.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
8.
Phosphatidic acid-dependent localization and basal de-phosphorylation of RA-GEFs regulate lymphocyte trafficking
Sayaka Ishihara, Tsuyoshi Sato, Guangwei Du, Daniele Guardavaccaro, Akihiko Nakajima, Satoshi Sawai, Tohru Kataoka, Koko Katagiri
BMC Biol. 2020; 18: 75. Published online 2020 Jun 29. doi: 10.1186/s12915-020-00809-0
PMCID:
PMC7325102
AbstractArticlePDF–2.1M
9.
Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant
Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely
Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089
PMCID:
PMC7295033
AbstractArticlePDF–2.7M
10.
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics
Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea
Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253
PMCID:
PMC6692770
AbstractArticlePDF–7.7M
11.
PSD-Zip70 Deficiency Causes Prefrontal Hypofunction Associated with Glutamatergic Synapse Maturation Defects by Dysregulation of Rap2 Activity
Taira Mayanagi, Hiroki Yasuda, Kenji Sobue
J Neurosci. 2015 Oct 21; 35(42): 14327–14340. doi: 10.1523/JNEUROSCI.2349-15.2015
PMCID:
PMC6605419
AbstractArticlePDF–3.5M
12.
Comprehensive behavioral analysis of mice deficient in Rapgef2 and Rapgef6, a subfamily of guanine nucleotide exchange factors for Rap small GTPases possessing the Ras/Rap-associating domain
Kazuhiro Maeta, Satoko Hattori, Junji Ikutomo, Hironori Edamatsu, Shymaa E. Bilasy, Tsuyoshi Miyakawa, Tohru Kataoka
Mol Brain. 2018; 11: 27. Published online 2018 May 10. doi: 10.1186/s13041-018-0370-y
PMCID:
PMC5946393
AbstractArticlePDF–3.3M
13.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
14.
NCS-Rapgef2, the Protein Product of the Neuronal Rapgef2 Gene, Is a Specific Activator of D1 Dopamine Receptor-Dependent ERK Phosphorylation in Mouse Brain
Sunny Zhihong Jiang, Wenqin Xu, Andrew C. Emery, Charles R. Gerfen, Maribeth V. Eiden, Lee E. Eiden
eNeuro. 2017 Sep-Oct; 4(5): ENEURO.0248-17.2017. Prepublished online 2017 Sep 11. Published online 2017 Sep 25. doi: 10.1523/ENEURO.0248-17.2017
Correction in:
eNeuro. 2018 Sep-Oct; 5(5): ENEURO.0379-18.2018.
PMCID:
PMC5611689
AbstractArticlePDF–6.1M
15.
Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling
Brent Wilkinson, Jing Li, Marcelo P. Coba
Sci Rep. 2017; 7: 5272. Published online 2017 Jul 13. doi: 10.1038/s41598-017-05588-3
PMCID:
PMC5509740
AbstractArticlePDF–4.6M
16.
Crucial Role of Rapgef2 and Rapgef6, a Family of Guanine Nucleotide Exchange Factors for Rap1 Small GTPase, in Formation of Apical Surface Adherens Junctions and Neural Progenitor Development in the Mouse Cerebral Cortex
Kazuhiro Maeta, Hironori Edamatsu, Kaori Nishihara, Junji Ikutomo, Shymaa E. Bilasy, Tohru Kataoka
eNeuro. 2016 May-Jun; 3(3): ENEURO.0142-16.2016. Prepublished online 2016 Jun 13. Published online 2016 Jun 23. doi: 10.1523/ENEURO.0142-16.2016
PMCID:
PMC4917737
AbstractArticlePDF–6.3M
17.
Rapgef2 Connects GPCR-Mediated cAMP Signals to ERK Activation in Neuronal and Endocrine Cells
Andrew C. Emery, Maribeth V. Eiden, Tomris Mustafa, Lee E. Eiden
Sci Signal. Author manuscript; available in PMC 2014 Feb 22.
Published in final edited form as: Sci Signal. 2013 Jun 25; 6(281): ra51. Published online 2013 Jun 25. doi: 10.1126/scisignal.2003993
PMCID:
PMC3932028
AbstractArticlePDF–2.6M
18.
JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function
Ana C. Monteiro, Ronen Sumagin, Carl R. Rankin, Giovanna Leoni, Michael J. Mina, Dirk M. Reiter, Thilo Stehle, Terence S. Dermody, Stacy A. Schaefer, Randy A. Hall, Asma Nusrat, Charles A. Parkos
Mol Biol Cell. 2013 Sep 15; 24(18): 2849–2860. doi: 10.1091/mbc.E13-06-0298
PMCID:
PMC3771947
AbstractArticlePDF–1.6M
19.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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