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Items: 1 to 20 of 36

1.
CBX7 silencing promoted liver regeneration by interacting with BMI1 and activating the Nrf2/ARE signaling pathway
Zhimin Dou, Fei Lu, Jinjing Hu, Bin Li, Xun Li
Sci Rep. 2024; 14: 11008. Published online 2024 May 14. doi: 10.1038/s41598-024-58248-8
PMCID:
PMC11094083
AbstractArticlePDF–8.3M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Polycomb group protein CBX7 represses cardiomyocyte proliferation via modulation of the TARDBP/RBM38 axis
Kyu-Won Cho, Mark Andrade, Seongho Bae, Sangsung Kim, Jin Eyun Kim, Er Yearn Jang, Sangho Lee, Ahsan Husain, Roy L. Sutliff, John W. Calvert, Changwon Park, Young-sup Yoon
Circulation. Author manuscript; available in PMC 2024 Jun 13.
Published in final edited form as: Circulation. 2023 Jun 13; 147(24): 1823–1842. Published online 2023 May 9. doi: 10.1161/CIRCULATIONAHA.122.061131
PMCID:
PMC10330362
AbstractArticlePDF–1.6M
4.
CBX7 Rejuvenates Late Passage Dental Pulp Stem Cells by Maintaining Stemness and Pro-angiogenic Ability
Yu Wu, Bing Li, Dandan Yu, Zhixuan Zhou, Ming Shen, Fei Jiang
Tissue Eng Regen Med. 2023 Jun; 20(3): 473–488. Published online 2023 Mar 15. doi: 10.1007/s13770-023-00521-4
PMCID:
PMC10219923
AbstractArticlePDF–4.5M
5.
A Polycomb domain found in committed cells impairs differentiation when introduced into PRC1 in pluripotent cells
Elizabeth S. Jaensch, Jinjin Zhu, Jesse C. Cochrane, Sharon K. Marr, Theresa A. Oei, Manashree Damle, Ethan Z. McCaslin, Robert E. Kingston
Mol Cell. Author manuscript; available in PMC 2022 Nov 18.
Published in final edited form as: Mol Cell. 2021 Nov 18; 81(22): 4677–4691.e8. Published online 2021 Oct 11. doi: 10.1016/j.molcel.2021.09.018
PMCID:
PMC8966356
AbstractArticlePDF–2.4M
6.
Mammalian CBX7 isoforms p36 and p22 exhibit differential responses to serum, varying functions for proliferation, and distinct subcellular localization
Kyu-Won Cho, Mark Andrade, Yu Zhang, Young-sup Yoon
Sci Rep. 2020; 10: 8061. Published online 2020 May 15. doi: 10.1038/s41598-020-64908-2
PMCID:
PMC7228926
AbstractArticlePDF–2.9M
7.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
8.
Polycomb protein family member CBX7 regulates intrinsic axon growth and regeneration
Run-Shan Duan, Gang-Bin Tang, Hong-Zhen Du, Yi-Wen Hu, Pei-Pei Liu, Ya-Jie Xu, Yu-Qiang Zeng, Shuang-Feng Zhang, Rui-Ying Wang, Zhao-Qian Teng, Chang-Mei Liu
Cell Death Differ. 2018 Sep; 25(9): 1598–1611. Published online 2018 Feb 19. doi: 10.1038/s41418-018-0064-0
PMCID:
PMC6143612
AbstractArticlePDF–4.7M
9.
USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components
Bo Ning, Wei Zhao, Chen Qian, Pinghua Liu, Qingtian Li, Wenyuan Li, Rong-Fu Wang
Nat Commun. 2017; 8: 349. Published online 2017 Aug 24. doi: 10.1038/s41467-017-00301-4
PMCID:
PMC5571198
AbstractArticlePDF–1.5M
10.
Live-cell single-molecule tracking reveals co-recognition of H3K27me3 and DNA targets polycomb Cbx7-PRC1 to chromatin
Chao Yu Zhen, Roubina Tatavosian, Thao Ngoc Huynh, Huy Nguyen Duc, Raibatak Das, Marko Kokotovic, Jonathan B Grimm, Luke D Lavis, Jun Lee, Frances J Mejia, Yang Li, Tingting Yao, Xiaojun Ren
eLife. 2016; 5: e17667. Published online 2016 Oct 10. doi: 10.7554/eLife.17667
PMCID:
PMC5056789
AbstractArticlePDF–6.3M
11.
CBX7 gene expression plays a negative role in adipocyte cell growth and differentiation
Floriana Forzati, Antonella Federico, Pierlorenzo Pallante, Marianna Colamaio, Francesco Esposito, Romina Sepe, Sara Gargiulo, Antonio Luciano, Claudio Arra, Giuseppe Palma, Giulia Bon, Stefania Bucher, Rita Falcioni, Arturo Brunetti, Sabrina Battista, Monica Fedele, Alfredo Fusco
Biol Open. 2014 Sep 15; 3(9): 871–879. Published online 2014 Sep 4. doi: 10.1242/bio.20147872
PMCID:
PMC4163664
AbstractArticlePDF–909K
12.
KAP1 Represses Differentiation-Inducible Genes in Embryonic Stem Cells through Cooperative Binding with PRC1 and Derepresses Pluripotency-Associated Genes
Bo Cheng, Xiaojun Ren, Tom K. Kerppola
Mol Cell Biol. 2014 Jun; 34(11): 2075–2091. doi: 10.1128/MCB.01729-13
PMCID:
PMC4019052
AbstractArticlePDF–2.2M
13.
Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen
Kifayathullah Liakath-Ali, Valerie E. Vancollie, Emma Heath, Damian P. Smedley, Jeanne Estabel, David Sunter, Tia DiTommaso, Jacqueline K. White, Ramiro Ramirez-Solis, Ian Smyth, Karen P. Steel, Fiona M. Watt
Nat Commun. 2014 Apr 11; 5: 3540. Published online 2014 Apr 11. doi: 10.1038/ncomms4540
PMCID:
PMC3996542
AbstractArticlePDF–4.0M
14.
Mitogen-activated Protein Kinase Signaling Mediates Phosphorylation of Polycomb Ortholog Cbx7
Hsan-au Wu, Jeremy L. Balsbaugh, Hollie Chandler, Athena Georgilis, Hayley Zullow, Jeffrey Shabanowitz, Donald F. Hunt, Jesus Gil, Gordon Peters, Emily Bernstein
J Biol Chem. 2013 Dec 20; 288(51): 36398–36408. Published online 2013 Nov 5. doi: 10.1074/jbc.M113.486266
PMCID:
PMC3868753
AbstractArticlePDF–2.1M
15.
Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes
Jacqueline K. White, Anna-Karin Gerdin, Natasha A. Karp, Ed Ryder, Marija Buljan, James N. Bussell, Jennifer Salisbury, Simon Clare, Neil J. Ingham, Christine Podrini, Richard Houghton, Jeanne Estabel, Joanna R. Bottomley, David G. Melvin, David Sunter, Niels C. Adams, The Sanger Institute Mouse Genetics Project, David Tannahill, Darren W. Logan, Daniel G. MacArthur, Jonathan Flint, Vinit B. Mahajan, Stephen H. Tsang, Ian Smyth, Fiona M. Watt, William C. Skarnes, Gordon Dougan, David J. Adams, Ramiro Ramirez-Solis, Allan Bradley, Karen P. Steel
Cell. 2013 Jul 18; 154(2): 452–464. doi: 10.1016/j.cell.2013.06.022
PMCID:
PMC3717207
AbstractArticlePDF–3.4M
16.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
17.
RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3
Lígia Tavares, Emilia Dimitrova, David Oxley, Judith Webster, Raymond Poot, Jeroen Demmers, Karel Bezstarosti, Stephen Taylor, Hiroki Ura, Hiroshi Koide, Anton Wutz, Miguel Vidal, Sarah Elderkin, Neil Brockdorff
Cell. 2012 Feb 17; 148(4): 664–678. doi: 10.1016/j.cell.2011.12.029
Correction in:
Cell. 2012 Jun 22; 149(7): 1647–1648.
PMCID:
PMC3281992
AbstractArticlePDF–1.9M
18.
MicroRNA Regulation of Cbx7 Mediates a Switch of Polycomb Orthologs during ESC Differentiation
Ana O'Loghlen, Ana M. Muñoz-Cabello, Alexandre Gaspar-Maia, Hsan-Au Wu, Ana Banito, Natalia Kunowska, Tomas Racek, Helen N. Pemberton, Patrizia Beolchi, Fabrice Lavial, Osamu Masui, Michiel Vermeulen, Thomas Carroll, Johannes Graumann, Edith Heard, Niall Dillon, Veronique Azuara, Ambrosius P. Snijders, Gordon Peters, Emily Bernstein, Jesus Gil
Cell Stem Cell. 2012 Jan 6; 10(1-5): 33–46. doi: 10.1016/j.stem.2011.12.004
PMCID:
PMC3277884
AbstractArticle
19.
CBX7 is a tumor suppressor in mice and humans
Floriana Forzati, Antonella Federico, Pierlorenzo Pallante, Adele Abbate, Francesco Esposito, Umberto Malapelle, Romina Sepe, Giuseppe Palma, Giancarlo Troncone, Marzia Scarfò, Claudio Arra, Monica Fedele, Alfredo Fusco
J Clin Invest. 2012 Feb 1; 122(2): 612–623. Published online 2012 Jan 3. doi: 10.1172/JCI58620
Correction in:
J Clin Invest. 2013 Feb 1; 123(2): 934.
PMCID:
PMC3266782
AbstractArticlePDF–3.6M
20.
An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment
Magnus D Lynch, Andrew J H Smith, Marco De Gobbi, Maria Flenley, Jim R Hughes, Douglas Vernimmen, Helena Ayyub, Jacqueline A Sharpe, Jacqueline A Sloane-Stanley, Linda Sutherland, Stephen Meek, Tom Burdon, Richard J Gibbons, David Garrick, Douglas R Higgs
EMBO J. 2012 Jan 18; 31(2): 317–329. Published online 2011 Nov 4. doi: 10.1038/emboj.2011.399
PMCID:
PMC3261560
AbstractArticlePDF–1.4M

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