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Select item 105768131.

KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors

Bo Zhang, Chen Zhao, Wenchen Shen, Wei Li, Yue Zheng, Xiangfei Kong, Junbao Wang, Xudong Wu, Tao Zeng, Ying Liu, Yan Zhou

Nat Commun. 2023; 14: 6489. Published online 2023 Oct 14. doi: 10.1038/s41467-023-42322-2

PMCID:: PMC10576813

Abstract Article PDF–13M

Select item 88000192.

Impaired KDM2B-mediated PRC1 recruitment to chromatin causes defective neural stem cell self-renewal and ASD/ID-like behaviors

Yuen Gao, Natalia Duque-Wilckens, Mohammad B. Aljazi, Adam J. Moeser, George I. Mias, Alfred J. Robison, Yi Zhang, Jin He

iScience. 2022 Feb 18; 25(2): 103742. Published online 2022 Jan 7. doi: 10.1016/j.isci.2022.103742

PMCID:: PMC8800019

Abstract Article PDF–3.4M

Select item 83338713.

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice

Feng Zhang, Xiong Zhao, Runmin Jiang, Yuying Wang, Xinli Wang, Yu Gu, Longyong Xu, Jing Ye, Charlie Degui Chen, Shuangping Guo, Dawei Zhang, Daqing Zhao

Front Cell Dev Biol. 2021; 9: 642931. Published online 2021 Jul 21. doi: 10.3389/fcell.2021.642931

PMCID:: PMC8333871

Abstract Article PDF–1.4M

Select item 83132394.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 73957666.

KDM2B promotes IL-6 production and inflammatory responses through Brg1-mediated chromatin remodeling

Qingqing Zhou, Yunkai Zhang, Bo Wang, Wenhui Zhou, Yong Bi, Wanwan Huai, Xi Chen, Yihan Chen, Zhongmin Liu, Xingguang Liu, Zhenzhen Zhan

Cell Mol Immunol. 2020 Aug; 17(8): 834–842. Published online 2019 Jun 13. doi: 10.1038/s41423-019-0251-z

PMCID:: PMC7395766

Abstract Article PDF–2.1M

Select item 70262497.

Long non-coding RNA LncKdm2b regulates cortical neuronal differentiation by cis-activating Kdm2b

Wei Li, Wenchen Shen, Bo Zhang, Kuan Tian, Yamu Li, Lili Mu, Zhiyuan Luo, Xiaoling Zhong, Xudong Wu, Ying Liu, Yan Zhou

Protein Cell. 2020 Mar; 11(3): 161–186. Published online 2019 Jul 17. doi: 10.1007/s13238-019-0650-z

PMCID:: PMC7026249

Abstract Article PDF–3.3M

Select item 67534928.

KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity

Anne H Turberfield, Takashi Kondo, Manabu Nakayama, Yoko Koseki, Hamish W King, Haruhiko Koseki, Robert J Klose

Nucleic Acids Res. 2019 Sep 26; 47(17): 9005–9023. Published online 2019 Jul 31. doi: 10.1093/nar/gkz607

PMCID:: PMC6753492

Abstract Article PDF–5.3M

Select item 67374099.

KDM2B in polycomb repressive complex 1.1 functions as a tumor suppressor in the initiation of T-cell leukemogenesis

Yusuke Isshiki, Yaeko Nakajima-Takagi, Motohiko Oshima, Kazumasa Aoyama, Mohamed Rizk, Shuhei Kurosawa, Atsunori Saraya, Takashi Kondo, Emiko Sakaida, Chiaki Nakaseko, Koutaro Yokote, Haruhiko Koseki, Atsushi Iwama

Blood Adv. 2019 Sep 10; 3(17): 2537–2549. Published online 2019 Aug 30. doi: 10.1182/bloodadvances.2018028522

PMCID:: PMC6737409

Abstract Article PDF–1.7M

Select item 628366310.

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition

John Arne Dahl, Inkyung Jung, Håvard Aanes, Gareth D. Greggains, Adeel Manaf, Mads Lerdrup, Guoqiang Li, Samantha Kuan, Bin Li, Ah Young Lee, Sebastian Preissl, Ingunn Jermstad, Mads Haugland Haugen, Rajikala Suganthan, Magnar Bjørås, Klaus Hansen, Knut Tomas Dalen, Peter Fedorcsak, Bing Ren, Arne Klungland

Nature. Author manuscript; available in PMC 2018 Dec 6.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 548–552. Published online 2016 Sep 14. doi: 10.1038/nature19360

PMCID:: PMC6283663

Abstract Article PDF–4.9M

Select item 561195511.

Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development

Elisabeth A. Rutledge, Jean-Denis Benazet, Andrew P. McMahon

Development. 2017 Sep 1; 144(17): 3177–3188. doi: 10.1242/dev.149112

PMCID:: PMC5611955

Abstract Article

Select item 506531512.

RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes

Nathan R Rose, Hamish W King, Neil P Blackledge, Nadezda A Fursova, Katherine JI Ember, Roman Fischer, Benedikt M Kessler, Robert J Klose

eLife. 2016; 5: e18591. Published online 2016 Oct 5. doi: 10.7554/eLife.18591

PMCID:: PMC5065315

Abstract Article PDF–4.5M

Select item 488866213.

Abnormal X chromosome inactivation and sex-specific gene dysregulation after ablation of FBXL10

Mathieu Boulard, John R. Edwards, Timothy H. Bestor

Epigenetics Chromatin. 2016; 9: 22. Published online 2016 May 31. doi: 10.1186/s13072-016-0069-1

PMCID:: PMC4888662

Abstract Article PDF–2.6M

Select item 476736114.

Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis

Jaclyn Andricovich, Yan Kai, Weiqun Peng, Adlen Foudi, Alexandros Tzatsos

J Clin Invest. 2016 Mar 1; 126(3): 905–920. Published online 2016 Jan 25. doi: 10.1172/JCI84014

PMCID:: PMC4767361

Abstract Article PDF–4.4M

Select item 470047915.

Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium

Andrei N. Mardaryev, Bo Liu, Valentina Rapisarda, Krzysztof Poterlowicz, Igor Malashchuk, Jana Rudolf, Andrey A. Sharov, Colin A. Jahoda, Michael Y. Fessing, Salvador A. Benitah, Guo-Liang Xu, Vladimir A. Botchkarev

J Cell Biol. 2016 Jan 4; 212(1): 77–89. doi: 10.1083/jcb.201506065

PMCID:: PMC4700479

Abstract Article PDF–2.4M

Select item 444786016.

Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2

Takeshi Ueda, Akiko Nagamachi, Keiyo Takubo, Norimasa Yamasaki, Hirotaka Matsui, Akinori Kanai, Yuichiro Nakata, Kenichiro Ikeda, Takaaki Konuma, Hideaki Oda, Linda Wolff, Zen-ichiro Honda, Xudong Wu, Kristian Helin, Atsushi Iwama, Toshio Suda, Toshiya Inaba, Hiroaki Honda

Blood. 2015 May 28; 125(22): 3437–3446. Prepublished online 2015 Apr 14. doi: 10.1182/blood-2014-03-562694

PMCID:: PMC4447860

Abstract Article

Select item 407878817.

Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes

Jin He, Li Shen, Ma Wan, Olena Taranova, Hao Wu, Yi Zhang

Nat Cell Biol. Author manuscript; available in PMC 2014 Jul 2.

Published in final edited form as: Nat Cell Biol. 2013 Apr; 15(4): 373–384. Published online 2013 Mar 17. doi: 10.1038/ncb2702

PMCID:: PMC4078788

Abstract Article PDF–2.5M

Select item 407349418.

The Central Role of EED in the Orchestration of Polycomb Group Complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Nat Commun. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127

PMCID:: PMC4073494

Abstract Article PDF–2.1M

Select item 404846419.

Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation

Neil P. Blackledge, Anca M. Farcas, Takashi Kondo, Hamish W. King, Joanna F. McGouran, Lars L.P. Hanssen, Shinsuke Ito, Sarah Cooper, Kaori Kondo, Yoko Koseki, Tomoyuki Ishikura, Hannah K. Long, Thomas W. Sheahan, Neil Brockdorff, Benedikt M. Kessler, Haruhiko Koseki, Robert J. Klose

Cell. 2014 Jun 5; 157(6): 1445–1459. doi: 10.1016/j.cell.2014.05.004

PMCID:: PMC4048464

Abstract Article PDF–4.1M

Select item 356179720.

KDM2B promotes pancreatic cancer via Polycomb-dependent and -independent transcriptional programs

Alexandros Tzatsos, Polina Paskaleva, Francesco Ferrari, Vikram Deshpande, Svetlana Stoykova, Gianmarco Contino, Kwok-Kin Wong, Fei Lan, Patrick Trojer, Peter J. Park, Nabeel Bardeesy

J Clin Invest. 2013 Feb 1; 123(2): 727–739. Published online 2013 Jan 16. doi: 10.1172/JCI64535

PMCID:: PMC3561797

Abstract Article PDF–2.8M

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