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Items: 1 to 20 of 27

1.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
2.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential
Leena Yadav, Elina Pietilä, Tiina Öhman, Xiaonan Liu, Arun K. Mahato, Yulia Sidorova, Kaisa Lehti, Mart Saarma, Markku Varjosalo
iScience. 2020 Feb 21; 23(2): 100871. Published online 2020 Jan 31. doi: 10.1016/j.isci.2020.100871
PMCID:
PMC7021549
AbstractArticlePDF–8.1M
5.
Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions
Kyuho Han, Edwin E. Jeng, Gaelen T. Hess, David W. Morgens, Amy Li, Michael C. Bassik
Nat Biotechnol. Author manuscript; available in PMC 2017 Sep 20.
Published in final edited form as: Nat Biotechnol. 2017 May; 35(5): 463–474. Published online 2017 Mar 20. doi: 10.1038/nbt.3834
PMCID:
PMC5557292
AbstractArticlePDF–3.4M
6.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
7.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
8.
Histone-binding of DPF2 mediates its repressive role in myeloid differentiation
Ferdinand M. Huber, Sarah M. Greenblatt, Andrew M. Davenport, Concepcion Martinez, Ye Xu, Ly P. Vu, Stephen D. Nimer, André Hoelz
Proc Natl Acad Sci U S A. 2017 Jun 6; 114(23): 6016–6021. Published online 2017 May 22. doi: 10.1073/pnas.1700328114
PMCID:
PMC5468650
AbstractArticlePDF–1.3M
9.
Hepatitis C virus infection inhibits a Src-kinase regulatory phosphatase and reduces T cell activation in vivo
Nirjal Bhattarai, James H. McLinden, Jinhua Xiang, M. Meleah Mathahs, Warren N. Schmidt, Thomas M. Kaufman, Jack T. Stapleton
PLoS Pathog. 2017 Feb; 13(2): e1006232. Published online 2017 Feb 24. doi: 10.1371/journal.ppat.1006232
PMCID:
PMC5342304
AbstractArticlePDF–2.2M
10.
Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family
Xu Li, Kim My Tran, Kathryn E. Aziz, Alexey V. Sorokin, Junjie Chen, Wenqi Wang
Mol Cell Proteomics. 2016 Sep; 15(9): 3030–3044. Published online 2016 Jul 18. doi: 10.1074/mcp.M116.060277
PMCID:
PMC5013315
AbstractArticlePDF–3.2M
11.
Linkage and association analysis of obesity traits reveals novel loci and interactions with dietary n-3 fatty acids in an Alaska Native (Yup’ik) population
Laura Kelly Vaughan, Howard W. Wiener, Stella Aslibekyan, David B. Allison, Peter J. Havel, Kimber L. Stanhope, Diane M. O’Brien, Scarlett E. Hopkins, Dominick J. Lemas, Bert B. Boyer, Hemant K. Tiwari
Metabolism. Author manuscript; available in PMC 2016 Jun 1.
Published in final edited form as: Metabolism. 2015 Jun; 64(6): 689–697. Published online 2015 Mar 5. doi: 10.1016/j.metabol.2015.02.008
PMCID:
PMC4408244
AbstractArticlePDF–396K
12.
Genome-Wide Association Study of d-Amphetamine Response in Healthy Volunteers Identifies Putative Associations, Including Cadherin 13 (CDH13)
Amy B. Hart, Barbara E. Engelhardt, Margaret C. Wardle, Greta Sokoloff, Matthew Stephens, Harriet de Wit, Abraham A. Palmer
PLoS One. 2012; 7(8): e42646. Published online 2012 Aug 28. doi: 10.1371/journal.pone.0042646
PMCID:
PMC3429486
AbstractArticlePDF–711K
13.
Epidermal Growth Factor Receptor (EGFR)-mediated Positive Feedback of Protein-tyrosine Phosphatase ϵ (PTPϵ) on ERK1/2 and AKT Protein Pathways Is Required for Survival of Human Breast Cancer Cells
Caroline E. Nunes-Xavier, Ari Elson, Rafael Pulido
J Biol Chem. 2012 Jan 27; 287(5): 3433–3444. Published online 2011 Nov 23. doi: 10.1074/jbc.M111.293928
PMCID:
PMC3270997
AbstractArticlePDF–3.3M
14.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
15.
Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score
Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl
Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159
Correction in:
Mol Med. 2012; 18(1): 729.
PMCID:
PMC2896464
AbstractArticlePDF–2.4M
16.
Novel HIV-1 Knockdown Targets Identified by an Enriched Kinases/Phosphatases shRNA Library Using a Long-Term Iterative Screen in Jurkat T-Cells
Sylvie Rato, Sara Maia, Paula M. Brito, Leonor Resende, Carina F. Pereira, Catarina Moita, Rui P. Freitas, José Moniz-Pereira, Nir Hacohen, Luis Ferreira Moita, Joao Goncalves
PLoS One. 2010; 5(2): e9276. Published online 2010 Feb 17. doi: 10.1371/journal.pone.0009276
PMCID:
PMC2822867
AbstractArticlePDF–1.2M
17.
Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome
Alastair J. Barr, Emilie Ugochukwu, Wen Hwa Lee, Oliver N.F. King, Panagis Filippakopoulos, Ivan Alfano, Pavel Savitsky, Nicola A. Burgess-Brown, Susanne Müller, Stefan Knapp
Cell. 2009 Jan 23; 136(2): 352–363. doi: 10.1016/j.cell.2008.11.038
PMCID:
PMC2638020
AbstractArticle
18.
Genes to Diseases (G2D) Computational Method to Identify Asthma Candidate Genes
Karine Tremblay, Mathieu Lemire, Camille Potvin, Alexandre Tremblay, Gary M. Hunninghake, Benjamin A. Raby, Thomas J. Hudson, Carolina Perez-Iratxeta, Miguel A. Andrade-Navarro, Catherine Laprise
PLoS One. 2008; 3(8): e2907. Published online 2008 Aug 6. doi: 10.1371/journal.pone.0002907
PMCID:
PMC2488373
AbstractArticlePDF–291K
19.
Genome-wide association with select biomarker traits in the Framingham Heart Study
Emelia J Benjamin, Josée Dupuis, Martin G Larson, Kathryn L Lunetta, Sarah L Booth, Diddahally R Govindaraju, Sekar Kathiresan, John F Keaney, Jr, Michelle J Keyes, Jing-Ping Lin, James B Meigs, Sander J Robins, Jian Rong, Renate Schnabel, Joseph A Vita, Thomas J Wang, Peter WF Wilson, Philip A Wolf, Ramachandran S Vasan
BMC Med Genet. 2007; 8(Suppl 1): S11. Published online 2007 Sep 19. doi: 10.1186/1471-2350-8-S1-S11
PMCID:
PMC1995615
AbstractArticlePDF–356K
20.
A Scan of Chromosome 10 Identifies a Novel Locus Showing Strong Association with Late-Onset Alzheimer Disease
Andrew Grupe, Yonghong Li, Charles Rowland, Petra Nowotny, Anthony L. Hinrichs, Scott Smemo, John S. K. Kauwe, Taylor J. Maxwell, Sara Cherny, Lisa Doil, Kristina Tacey, Ryan van Luchene, Amanda Myers, Fabienne Wavrant-De Vrièze, Mona Kaleem, Paul Hollingworth, Luke Jehu, Catherine Foy, Nicola Archer, Gillian Hamilton, Peter Holmans, Chris M. Morris, Joseph Catanese, John Sninsky, Thomas J. White, John Powell, John Hardy, Michael O’Donovan, Simon Lovestone, Lesley Jones, John C. Morris, Leon Thal, Michael Owen, Julie Williams, Alison Goate
Am J Hum Genet. 2006 Jan; 78(1): 78–88. Published online 2005 Nov 15. doi: 10.1086/498851
PMCID:
PMC1380225
AbstractArticlePDF–329K

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