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Select item 86400371.

Atlas of RNA editing events affecting protein expression in aged and Alzheimer’s disease human brain tissue

Yiyi Ma, Eric B. Dammer, Daniel Felsky, Duc M. Duong, Hans-Ulrich Klein, Charles C. White, Maotian Zhou, Benjamin A. Logsdon, Cristin McCabe, Jishu Xu, Minghui Wang, Thomas S. Wingo, James J. Lah, Bin Zhang, Julie Schneider, Mariet Allen, Xue Wang, Nilüfer Ertekin-Taner, Nicholas T. Seyfried, Allan I. Levey, David A. Bennett, Philip L. De Jager

Nat Commun. 2021; 12: 7035. Published online 2021 Dec 2. doi: 10.1038/s41467-021-27204-9

PMCID:: PMC8640037

Abstract Article PDF–4.8M

Select item 76542832.

Distinct pharmacological profiles of ORAI1, ORAI2, and ORAI3 channels

Xuexin Zhang, Ping Xin, Ryan E. Yoast, Scott M. Emrich, Martin T. Johnson, Trayambak Pathak, J. Cory Benson, Iman Azimi, Donald L. Gill, Gregory R. Monteith, Mohamed Trebak

Cell Calcium. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Cell Calcium. 2020 Nov; 91: 102281. Published online 2020 Aug 29. doi: 10.1016/j.ceca.2020.102281

PMCID:: PMC7654283

Abstract Article PDF–2.4M

Select item 74323743.

ORAI2 Down-Regulation Potentiates SOCE and Decreases Aβ42 Accumulation in Human Neuroglioma Cells

Elena Scremin, Mario Agostini, Alessandro Leparulo, Tullio Pozzan, Elisa Greotti, Cristina Fasolato

Int J Mol Sci. 2020 Aug; 21(15): 5288. Published online 2020 Jul 25. doi: 10.3390/ijms21155288

PMCID:: PMC7432374

Abstract Article PDF–4.2M

Select item 72291784.

The native ORAI channel trio underlies the diversity of Ca²⁺ signaling events

Ryan E. Yoast, Scott M. Emrich, Xuexin Zhang, Ping Xin, Martin T. Johnson, Adam J. Fike, Vonn Walter, Nadine Hempel, David I. Yule, James Sneyd, Donald L. Gill, Mohamed Trebak

Nat Commun. 2020; 11: 2444. Published online 2020 May 15. doi: 10.1038/s41467-020-16232-6

PMCID:: PMC7229178

Abstract Article PDF–3.9M

Select item 68550035.

Identification of Key Pathways and Genes in the Orai2 Mediated Classical and Mesenchymal Subtype of Glioblastoma by Bioinformatic Analyses

Feng Yuan, Li Yi, Long Hai, Yingshuai Wang, Yihan Yang, Tao Li, Luqing Tong, Haiwen Ma, Peidong Liu, Haolang Ming, Bingcheng Ren, Shengping Yu, Yu Lin, Xuejun Yang

Dis Markers. 2019; 2019: 7049294. Published online 2019 Oct 20. doi: 10.1155/2019/7049294

PMCID:: PMC6855003

Abstract Article PDF–3.7M

Select item 58269266.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 57149467.

ORAI channels are critical for receptor-mediated endocytosis of albumin

Bo Zeng, Gui-Lan Chen, Eliana Garcia-Vaz, Sunil Bhandari, Nikoleta Daskoulidou, Lisa M. Berglund, Hongni Jiang, Thomas Hallett, Lu-Ping Zhou, Li Huang, Zi-Hao Xu, Viji Nair, Robert G. Nelson, Wenjun Ju, Matthias Kretzler, Stephen L. Atkin, Maria F. Gomez, Shang-Zhong Xu

Nat Commun. 2017; 8: 1920. Published online 2017 Dec 4. doi: 10.1038/s41467-017-02094-y

PMCID:: PMC5714946

Abstract Article PDF–3.5M

Select item 56636398.

CRACM1, CRACM2, and CRACM3 Are Store-Operated Ca²⁺ Channels with Distinct Functional Properties

Annette Lis, Christine Peinelt, Andreas Beck, Suhel Parvez, Mahealani Monteilh-Zoller, Andrea Fleig, Reinhold Penner

Curr Biol. Author manuscript; available in PMC 2017 Oct 31.

Published in final edited form as: Curr Biol. 2007 May 1; 17(9): 794–800. Published online 2007 Apr 19. doi: 10.1016/j.cub.2007.03.065

PMCID:: PMC5663639

Abstract Article PDF–657K

Select item 39463869.

Enhanced Expression of Stim, Orai, and TRPC Transcripts and Proteins in Endothelial Progenitor Cells Isolated from Patients with Primary Myelofibrosis

Silvia Dragoni, Umberto Laforenza, Elisa Bonetti, Marta Reforgiato, Valentina Poletto, Francesco Lodola, Cinzia Bottino, Daniele Guido, Alessandra Rappa, Sumedha Pareek, Mario Tomasello, Maria Rosa Guarrera, Maria Pia Cinelli, Adele Aronica, Germano Guerra, Giovanni Barosi, Franco Tanzi, Vittorio Rosti, Francesco Moccia

PLoS One. 2014; 9(3): e91099. Published online 2014 Mar 6. doi: 10.1371/journal.pone.0091099

PMCID:: PMC3946386

Abstract Article PDF–1.2M

Select item 376930410.

The Contribution of Orai(CRACM)1 and Orai(CRACM)2 Channels in Store-Operated Ca²⁺ Entry and Mediator Release in Human Lung Mast Cells

Ian Ashmole, S. Mark Duffy, Mark L. Leyland, Peter Bradding

PLoS One. 2013; 8(9): e74895. Published online 2013 Sep 10. doi: 10.1371/journal.pone.0074895

PMCID:: PMC3769304

Abstract Article PDF–632K

Select item 317805911.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 287586512.

A novel EF-hand protein, CRACR2A, is a cytosolic Ca²⁺ sensor that stabilizes CRAC channels in T cells

Sonal Srikanth, Hea-Jin Jung, Kyun-Do Kim, Puneet Souda, Julian Whitelegge, Yousang Gwack

Nat Cell Biol. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: Nat Cell Biol. 2010 May; 12(5): 436–446. Published online 2010 Apr 25. doi: 10.1038/ncb2045

PMCID:: PMC2875865

Abstract Article PDF–2.9M

Select item 275589213.

Molecular Determinants of the Coupling between STIM1 and Orai Channels: DIFFERENTIAL ACTIVATION OF Orai1–3 CHANNELS BY A STIM1 COILED-COIL MUTANT

Irene Frischauf, Martin Muik, Isabella Derler, Judith Bergsmann, Marc Fahrner, Rainer Schindl, Klaus Groschner, Christoph Romanin

J Biol Chem. 2009 Aug 7; 284(32): 21696–21706. Published online 2009 Jun 8. doi: 10.1074/jbc.M109.018408

PMCID:: PMC2755892

Abstract Article PDF–3.9M

Select item 273284114.

Molecular determinants of fast Ca²⁺-dependent inactivation and gating of the Orai channels

Kyu Pil Lee, Joseph P. Yuan, Weizhong Zeng, Insuk So, Paul F. Worley, Shmuel Muallem

Proc Natl Acad Sci U S A. 2009 Aug 25; 106(34): 14687–14692. Published online 2009 Aug 12. doi: 10.1073/pnas.0904664106

PMCID:: PMC2732841

Abstract Article PDF–1.6M

Select item 266338515.

SOAR and the polybasic STIM1 domains gate and regulate the Orai channels

Joseph P. Yuan, Weizhong Zeng, Michael R. Dorwart, Young-Jin Choi, Paul F. Worley, Shmuel Muallem

Nat Cell Biol. Author manuscript; available in PMC 2009 Sep 1.

Published in final edited form as: Nat Cell Biol. 2009 Mar; 11(3): 337–343. Published online 2009 Feb 1. doi: 10.1038/ncb1842

PMCID:: PMC2663385

Abstract Article PDF–2.2M

Select item 253877816.

2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels

Christine Peinelt, Annette Lis, Andreas Beck, Andrea Fleig, Reinhold Penner

J Physiol. 2008 Jul 1; 586(Pt 13): 3061–3073. Published online 2008 Apr 10. doi: 10.1113/jphysiol.2008.151365

PMCID:: PMC2538778

Abstract Article PDF–1.3M

Select item 163382217.

LARGE STORE-OPERATED CALCIUM-SELECTIVE CURRENTS DUE TO CO-EXPRESSION OF ORAI1 OR ORAI2 WITH THE INTRACELLULAR CALCIUM SENSOR, STIM1

Jason C. Mercer, Wayne I. DeHaven, Jeremy T. Smyth, Barbara Wedel, Rebecca R. Boyles, Gary S. Bird, James W. Putney, Jr.

J Biol Chem. Author manuscript; available in PMC 2007 Aug 25.

Published in final edited form as: J Biol Chem. 2006 Aug 25; 281(34): 24979–24990. Published online 2006 Jun 28. doi: 10.1074/jbc.M604589200

PMCID:: PMC1633822

Abstract Article PDF–2.9M

Select item 135612918.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 52892819.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

Select item 52484220.

Large-scale cDNA transfection screening for genes related to cancer development and progression

Dafang Wan, Yi Gong, Wenxin Qin, Pingping Zhang, Jinjun Li, Lin Wei, Xiaomei Zhou, Hongnian Li, Xiaokun Qiu, Fei Zhong, Liping He, Jian Yu, Genfu Yao, Huiqiu Jiang, Lianfang Qian, Ye Yu, Huiqun Shu, Xianlian Chen, Huili Xu, Minglei Guo, Zhimei Pan, Yan Chen, Chao Ge, Shengli Yang, Jianren Gu

Proc Natl Acad Sci U S A. 2004 Nov 2; 101(44): 15724–15729. Published online 2004 Oct 21. doi: 10.1073/pnas.0404089101

Correction in:: Proc Natl Acad Sci U S A. 2004 Dec 14; 101(50): 17565.

PMCID:: PMC524842

Abstract Article PDF–245K

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