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Items: 1 to 20 of 31

1.
Effect of TGF-β1 on eosinophils to induce cysteinyl leukotriene E4 production in aspirin-exacerbated respiratory disease
Youngwoo Choi, Soyoon Sim, Dong-Hyun Lee, Hee-Ra Lee, Ga-Young Ban, Yoo Seob Shin, Yoon-Keun Kim, Hae-Sim Park
PLoS One. 2021; 16(8): e0256237. Published online 2021 Aug 26. doi: 10.1371/journal.pone.0256237
PMCID:
PMC8389430
AbstractArticlePDF–1.2M
2.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
3.
Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions
Kyuho Han, Edwin E. Jeng, Gaelen T. Hess, David W. Morgens, Amy Li, Michael C. Bassik
Nat Biotechnol. Author manuscript; available in PMC 2017 Sep 20.
Published in final edited form as: Nat Biotechnol. 2017 May; 35(5): 463–474. Published online 2017 Mar 20. doi: 10.1038/nbt.3834
PMCID:
PMC5557292
AbstractArticlePDF–3.4M
4.
Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages
Jesmond Dalli, Iliyan Vlasakov, Ian R. Riley, Ana R. Rodriguez, Bernd W. Spur, Nicos A. Petasis, Nan Chiang, Charles N. Serhan
Proc Natl Acad Sci U S A. 2016 Oct 25; 113(43): 12232–12237. Published online 2016 Oct 6. doi: 10.1073/pnas.1607003113
PMCID:
PMC5087052
AbstractArticlePDF–1.0M
5.
Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity
Shabbir Ahmad, A. Jimmy Ytterberg, Madhuranayaki Thulasingam, Fredrik Tholander, Tomas Bergman, Roman Zubarev, Anders Wetterholm, Agnes Rinaldo-Matthis, Jesper Z. Haeggström
J Biol Chem. 2016 Aug 26; 291(35): 18410–18418. Published online 2016 Jun 30. doi: 10.1074/jbc.M116.735647
PMCID:
PMC5000086
AbstractArticlePDF–1.3M
6.
Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM
Damian Niegowski, Thea Kleinschmidt, Ulrika Olsson, Shabbir Ahmad, Agnes Rinaldo-Matthis, Jesper Z. Haeggström
J Biol Chem. 2014 Feb 21; 289(8): 5199–5207. Published online 2013 Dec 23. doi: 10.1074/jbc.M113.534628
PMCID:
PMC3931076
AbstractArticlePDF–1.8M
7.
Elevated levels of leukotriene C4 synthase mRNA distinguish a subpopulation of eosinophilic oesophagitis patients
Willem S. Lexmond, Michael Pardo, Katharine Rooney, Jeremy A. Goettel, Scott B. Snapper, Elizabeth H. Yen, Eleonora Dehlink, Samuel Nurko, Edda Fiebiger
Clin Exp Allergy. Author manuscript; available in PMC 2014 Aug 1.
Published in final edited form as: Clin Exp Allergy. 2013 Aug; 43(8): 902–913. doi: 10.1111/cea.12146
PMCID:
PMC3728707
AbstractArticlePDF–1.9M
8.
Seleno-detergent MAD phasing of leukotriene C4 synthase in complex with dodecyl-β-d-selenomaltoside
Hiromichi Saino, Hideo Ago, Yoko Ukita, Masashi Miyano
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1; 67(Pt 12): 1666–1673. Published online 2011 Nov 29. doi: 10.1107/S1744309111042345
PMCID:
PMC3232166
AbstractArticlePDF–1.5M
9.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
10.
The Catalytic Architecture of Leukotriene C4 Synthase with Two Arginine Residues
Hiromichi Saino, Yoko Ukita, Hideo Ago, Daisuke Irikura, Atsushi Nisawa, Go Ueno, Masaki Yamamoto, Yoshihide Kanaoka, Bing K. Lam, K. Frank Austen, Masashi Miyano
J Biol Chem. 2011 May 6; 286(18): 16392–16401. Published online 2011 Mar 16. doi: 10.1074/jbc.M110.150177
PMCID:
PMC3091245
AbstractArticlePDF–1.8M
11.
Arginine 104 Is a Key Catalytic Residue in Leukotriene C4 Synthase
Agnes Rinaldo-Matthis, Anders Wetterholm, Daniel Martinez Molina, Johanna Holm, Damian Niegowski, Eva Ohlson, Pär Nordlund, Ralf Morgenstern, Jesper Z. Haeggström
J Biol Chem. 2010 Dec 24; 285(52): 40771–40776. Published online 2010 Oct 27. doi: 10.1074/jbc.M110.105940
PMCID:
PMC3003377
AbstractArticlePDF–617K
12.
Increased expression of leukotriene C4 synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm
Antonio Di Gennaro, Dick Wågsäter, Mikko I. Mäyränpää, Anders Gabrielsen, Jesper Swedenborg, Anders Hamsten, Bengt Samuelsson, Per Eriksson, Jesper Z. Haeggström
Proc Natl Acad Sci U S A. 2010 Dec 7; 107(49): 21093–21097. Published online 2010 Nov 15. doi: 10.1073/pnas.1015166107
PMCID:
PMC3000261
AbstractArticlePDF–363K
13.
Fulfilling the Promise of Personalized Medicine? Systematic Review and Field Synopsis of Pharmacogenetic Studies
Michael V. Holmes, Tina Shah, Christine Vickery, Liam Smeeth, Aroon D. Hingorani, Juan P. Casas
PLoS One. 2009; 4(12): e7960. Published online 2009 Dec 2. doi: 10.1371/journal.pone.0007960
PMCID:
PMC2778625
AbstractArticlePDF–768K
14.
A Meta-Analysis of Candidate Gene Polymorphisms and Ischemic Stroke in Six Study Populations: Association of Lymphotoxin-alpha in Non-hypertensive Patients
Xingyu Wang, Suzanne Cheng, Victoria H. Brophy, Henry A. Erlich, Christine Mannhalter, Klaus Berger, Wolfgang Lalouschek, Warren S. Browner, Yu Shi, Ernst B. Ringelstein, Christof Kessler, Jan Luedemann, Klaus Lindpaintner, Lisheng Liu, Paul M. Ridker, Robert Y.L. Zee, Nancy R. Cook
Stroke. Author manuscript; available in PMC 2010 Mar 1.
Published in final edited form as: Stroke. 2009 Mar; 40(3): 683–695. Published online 2009 Jan 8. doi: 10.1161/STROKEAHA.108.524587
PMCID:
PMC2757095
AbstractArticlePDF–484K
15.
5-lipoxygenase Pharmacogenetics in Asthma: Overlap with CystLTR1 Loci
K.G. Tantisira, J. Lima, J. Sylvia, B. Klanderman, S.T. Weiss
Pharmacogenet Genomics. Author manuscript; available in PMC 2010 Mar 1.
Published in final edited form as: Pharmacogenet Genomics. 2009 Mar; 19(3): 244–247. doi: 10.1097/FPC.0b013e328326e0b1
PMCID:
PMC2731688
AbstractArticlePDF–438K
16.
Polymorphic variation in NFKB1 and other aspirin-related genes and risk of Hodgkin lymphoma
Ellen T. Chang, Brenda M. Birmann, Julie L. Kasperzyk, David V. Conti, Peter Kraft, Richard F. Ambinder, Tongzhang Zheng, Nancy E. Mueller
Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2010 Mar 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2009 Mar; 18(3): 976–986. Published online 2009 Feb 17. doi: 10.1158/1055-9965.EPI-08-1130
PMCID:
PMC2720066
AbstractArticlePDF–346K
17.
A Candidate Gene Association Study of 77 Polymorphisms in Migraine
Markus Schürks, Tobias Kurth, Julie E. Buring, Robert Y.L. Zee
J Pain. Author manuscript; available in PMC 2010 Jul 1.
Published in final edited form as: J Pain. 2009 Jul; 10(7): 759–766. doi: 10.1016/j.jpain.2009.01.326
PMCID:
PMC2704575
AbstractArticlePDF–316K
18.
Genetic Risk Factors in Recurrent Venous Thromboembolism: A Multilocus, Population-Based, Prospective Approach
Robert YL Zee, Vadim Bubes, Sanjay Shrivastava, Paul M Ridker, Robert J Glynn
Clin Chim Acta. Author manuscript; available in PMC 2010 Apr 1.
Published in final edited form as: Clin Chim Acta. 2009 Apr; 402(1-2): 189–192. doi: 10.1016/j.cca.2009.01.011
PMCID:
PMC2693946
AbstractArticlePDF–72K
19.
Influence of Leukotriene Pathway Polymorphisms on Response to Montelukast in Asthma
John J. Lima, Shu Zhang, Audrey Grant, Lianhe Shao, Kelan G. Tantisira, Hooman Allayee, Jianwei Wang, James Sylvester, Janet Holbrook, Robert Wise, Scott T. Weiss, Kathleen Barnes
Am J Respir Crit Care Med. 2006 Feb 15; 173(4): 379–385. Published online 2005 Nov 17. doi: 10.1164/rccm.200509-1412OC
PMCID:
PMC2662939
AbstractArticlePDF–118K
20.
Identification of Novel Single Nucleotide Polymorphisms in Inflammatory Genes as Risk Factors Associated with Trachomatous Trichiasis
Berna Atik, Troy A. Skwor, Ram Prasad Kandel, Bassant Sharma, Him Kant Adhikari, Lori Steiner, Henry Erlich, Deborah Dean
PLoS One. 2008; 3(10): e3600. Published online 2008 Oct 31. doi: 10.1371/journal.pone.0003600
PMCID:
PMC2572999
AbstractArticlePDF–304K

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