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Select item 108724771.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102333683.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 99845324.

Genetic requirements for repair of lesions caused by single genomic ribonucleotides in S phase

Natalie Schindler, Matthias Tonn, Vanessa Kellner, Jia Jun Fung, Arianna Lockhart, Olga Vydzhak, Thomas Juretschke, Stefanie Möckel, Petra Beli, Anton Khmelinskii, Brian Luke

Nat Commun. 2023; 14: 1227. Published online 2023 Mar 3. doi: 10.1038/s41467-023-36866-6

PMCID:: PMC9984532

Abstract Article PDF–3.0M

Select item 92098115.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 91175466.

Nej1 interacts with Sae2 at DNA double-stranded breaks to inhibit DNA resection

Aditya Mojumdar, Nancy Adam, Jennifer A. Cobb

J Biol Chem. 2022 Jun; 298(6): 101937. Published online 2022 Apr 13. doi: 10.1016/j.jbc.2022.101937

PMCID:: PMC9117546

Abstract Article PDF–2.7M

Select item 84833527.

Antagonistic relationship of NuA4 with the non-homologous end-joining machinery at DNA damage sites

Salar Ahmad, Valérie Côté, Xue Cheng, Gaëlle Bourriquen, Vasileia Sapountzi, Mohammed Altaf, Jacques Côté

PLoS Genet. 2021 Sep; 17(9): e1009816. Published online 2021 Sep 20. doi: 10.1371/journal.pgen.1009816

PMCID:: PMC8483352

Abstract Article PDF–2.7M

Select item 82196818.

Inhibition of MRN activity by a telomere protein motif

Freddy Khayat, Elda Cannavo, Majedh Alshmery, William R. Foster, Charly Chahwan, Martino Maddalena, Christopher Smith, Antony W. Oliver, Adam T. Watson, Antony M. Carr, Petr Cejka, Alessandro Bianchi

Nat Commun. 2021; 12: 3856. Published online 2021 Jun 22. doi: 10.1038/s41467-021-24047-2

PMCID:: PMC8219681

Abstract Article PDF–3.3M

Select item 81155999.

Mechanism of MRX inhibition by Rif2 at telomeres

Florian Roisné-Hamelin, Sabrina Pobiega, Kévin Jézéquel, Simona Miron, Jordane Dépagne, Xavier Veaute, Didier Busso, Marie-Hélène Le Du, Isabelle Callebaut, Jean-Baptiste Charbonnier, Philippe Cuniasse, Sophie Zinn-Justin, Stéphane Marcand

Nat Commun. 2021; 12: 2763. Published online 2021 May 12. doi: 10.1038/s41467-021-23035-w

PMCID:: PMC8115599

Abstract Article PDF–3.9M

Select item 811281710.

A role for the Mre11–Rad50–Xrs2 complex in gene expression and chromosome organization

Romain Forey, Antoine Barthe, Mireille Tittel-Elmer, Maxime Wery, Marie-Bénédicte Barrault, Cécile Ducrot, Andrew Seeber, Nils Krietenstein, Ugo Szachnowski, Magdalena Skrzypczak, Krzysztof Ginalski, Maga Rowicka, Jennifer Cobb, Oliver J. Rando, Julie Soutourina, Michel Werner, Karine Dubrana, Susan M. Gasser, Antonin Morillon, Philippe Pasero, Armelle Lengronne, Jérôme Poli

Mol Cell. Author manuscript; available in PMC 2021 May 11.

Published in final edited form as: Mol Cell. 2021 Jan 7; 81(1): 183–197.e6. Published online 2020 Dec 4. doi: 10.1016/j.molcel.2020.11.010

PMCID:: PMC8112817

Abstract Article PDF–2.5M

Select item 804059811.

Modeling DNA trapping of anticancer therapeutic targets using missense mutations identifies dominant synthetic lethal interactions

Akil Hamza, Leanne Amitzi, Lina Ma, Maureen R. M. Driessen, Nigel J. O'Neil, Philip Hieter

Proc Natl Acad Sci U S A. 2021 Apr 6; 118(14): e2100240118. Published online 2021 Mar 29. doi: 10.1073/pnas.2100240118

PMCID:: PMC8040598

Abstract Article PDF–1.5M

Select item 788674612.

Participation of the HIM1 gene of yeast Saccharomyces cerevisiae in the error-free branch of post-replicative repair and role Polη in him1-dependent mutagenesis

E. A. Alekseeva, T. A. Evstyukhina, V. T. Peshekhonov, V. G. Korolev

Curr Genet. 2021; 67(1): 141–151. Published online 2020 Oct 31. doi: 10.1007/s00294-020-01115-6

PMCID:: PMC7886746

Abstract Article PDF–2.1M

Select item 732543513.

A genetic interaction map centered on cohesin reveals auxiliary factors involved in sister chromatid cohesion in S. cerevisiae

Su Ming Sun, Amandine Batté, Mireille Elmer, Sophie C. van der Horst, Tibor van Welsem, Gordon Bean, Trey Ideker, Fred van Leeuwen, Haico van Attikum

J Cell Sci. 2020 May 15; 133(10): jcs237628. Published online 2020 May 22. doi: 10.1242/jcs.237628

PMCID:: PMC7325435

Abstract Article

Select item 689338014.

Tel1 Activation by the MRX Complex Is Sufficient for Telomere Length Regulation but Not for the DNA Damage Response in Saccharomyces cerevisiae

Rebecca Keener, Carla J. Connelly, Carol W. Greider

Genetics. 2019 Dec; 213(4): 1271–1288. Published online 2019 Oct 23. doi: 10.1534/genetics.119.302713

PMCID:: PMC6893380

Abstract Article PDF–2.0M

Select item 679691215.

Structural basis of allosteric regulation of Tel1/ATM kinase

Jiyu Xin, Zhu Xu, Xuejuan Wang, Yanhua Tian, Zhihui Zhang, Gang Cai

Cell Res. 2019 Aug; 29(8): 655–665. Published online 2019 May 16. doi: 10.1038/s41422-019-0176-1

PMCID:: PMC6796912

Abstract Article PDF–4.2M

Select item 675347116.

Rad5 dysregulation drives hyperactive recombination at replication forks resulting in cisplatin sensitivity and genome instability

Eric E Bryant, Ivana Šunjevarić, Luke Berchowitz, Rodney Rothstein, Robert J D Reid

Nucleic Acids Res. 2019 Sep 26; 47(17): 9144–9159. Published online 2019 Jul 27. doi: 10.1093/nar/gkz631

PMCID:: PMC6753471

Abstract Article PDF–6.0M

Select item 666418217.

Activation of Tel1^ATM kinase requires Rad50 ATPase and long nucleosome-free DNA but no DNA ends

Sarem Hailemariam, Sandeep Kumar, Peter M. Burgers

J Biol Chem. 2019 Jun 28; 294(26): 10120–10130. Published online 2019 May 9. doi: 10.1074/jbc.RA119.008410

PMCID:: PMC6664182

Abstract Article PDF–2.1M

Select item 661490418.

Tolerance of DNA Replication Stress Is Promoted by Fumarate Through Modulation of Histone Demethylation and Enhancement of Replicative Intermediate Processing in Saccharomyces cerevisiae

Faeze Saatchi, Ann L. Kirchmaier

Genetics. 2019 Jul; 212(3): 631–654. Published online 2019 May 13. doi: 10.1534/genetics.119.302238

PMCID:: PMC6614904

Abstract Article PDF–2.0M

Select item 646824719.

The ATP-bound conformation of the Mre11–Rad50 complex is essential for Tel1/ATM activation

Corinne Cassani, Jacopo Vertemara, Matteo Bassani, Antonio Marsella, Renata Tisi, Giuseppe Zampella, Maria Pia Longhese

Nucleic Acids Res. 2019 Apr 23; 47(7): 3550–3567. Published online 2019 Jan 30. doi: 10.1093/nar/gkz038

PMCID:: PMC6468247

Abstract Article PDF–18M

Select item 643118020.

Stepwise 5′ DNA end-specific resection of DNA breaks by the Mre11-Rad50-Xrs2 and Sae2 nuclease ensemble

Elda Cannavo, Giordano Reginato, Petr Cejka

Proc Natl Acad Sci U S A. 2019 Mar 19; 116(12): 5505–5513. Published online 2019 Feb 28. doi: 10.1073/pnas.1820157116

PMCID:: PMC6431180

Abstract Article PDF–1.8M

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