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Select item 89179351.

A murine model of hereditary pulmonary alveolar proteinosis caused by homozygous Csf2ra gene disruption

Kenjiro Shima, Paritha Arumugam, Anthony Sallese, Yuko Horio, Yan Ma, Cole Trapnell, Matthew Wessendarp, Claudia Chalk, Cormac McCarthy, Brenna C. Carey, Bruce C. Trapnell, Takuji Suzuki

Am J Physiol Lung Cell Mol Physiol. 2022 Mar 1; 322(3): L438–L448. Published online 2022 Jan 19. doi: 10.1152/ajplung.00175.2021

PMCID:: PMC8917935

Abstract Article

Select item 87596082.

CD116⁺ fetal precursors migrate to the perinatal lung and give rise to human alveolar macrophages

Elza Evren, Emma Ringqvist, Jean-Marc Doisne, Anna Thaller, Natalie Sleiers, Richard A. Flavell, James P. Di Santo, Tim Willinger

J Exp Med. 2022 Feb 7; 219(2): e20210987. Published online 2022 Jan 12. doi: 10.1084/jem.20210987

PMCID:: PMC8759608

Abstract Article PDF–9.6M

Select item 68507003.

Neutrophil GM‐CSF receptor dynamics in acute lung injury

Silvia De Alessandris, G. John Ferguson, Alison J. Dodd, Jatinder K. Juss, Abhinandan Devaprasad, Siân Piper, Owen Wyatt, Helen Killick, Dominic J. Corkill, E. Suzanne Cohen, Aridaman Pandit, Timothy R.D.J. Radstake, Rosalind Simmonds, Alison M. Condliffe, Matthew A. Sleeman, Andrew S. Cowburn, Donna K. Finch, Edwin R. Chilvers

J Leukoc Biol. 2019 Jun; 105(6): 1183–1194. Published online 2019 Apr 3. doi: 10.1002/JLB.3MA0918-347R

PMCID:: PMC6850700

Abstract Article PDF–659K

Select item 63918464.

Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte–Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn’s Disease

Lee A Denson, Ingrid Jurickova, Rebekah Karns, Kelly A Shaw, David J Cutler, David Okou, C Alexander Valencia, Anne Dodd, Kajari Mondal, Bruce J Aronow, Yael Haberman, Aaron Linn, Adam Price, Ramona Bezold, Kathleen Lake, Kimberly Jackson, Thomas D Walters, Anne Griffiths, Robert N Baldassano, Joshua D Noe, Jeffrey S Hyams, Wallace V Crandall, Barbara S Kirschner, Melvin B Heyman, Scott Snapper, Stephen L Guthery, Marla C Dubinsky, Neal S Leleiko, Anthony R Otley, Ramnik J Xavier, Christine Stevens, Mark J Daly, Michael E Zwick, Subra Kugathasan

Inflamm Bowel Dis. 2019 Mar; 25(3): 547–560. Published online 2018 Aug 13. doi: 10.1093/ibd/izy265

PMCID:: PMC6391846

Abstract Article PDF–1.5M

Select item 56472605.

Targeting the GM-CSF receptor for the treatment of CNS autoimmunity

Igal Ifergan, Todd S. Davidson, Hania Kebir, Dan Xu, Daphne Palacios-Macapagal, Jennifer Cann, Jane M. Rodgers, Zoe N. Hunter, Camille L. Pittet, Sara Beddow, Clare A. Jones, Alexandre Prat, Matthew A. Sleeman, Stephen D. Miller

J Autoimmun. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: J Autoimmun. 2017 Nov; 84: 1–11. Published online 2017 Jun 20. doi: 10.1016/j.jaut.2017.06.005

PMCID:: PMC5647260

Abstract Article PDF–3.5M

Select item 55593066.

A genome-wide CRISPR screen identifies genes critical for resistance to FLT3 inhibitor AC220

Panpan Hou, Chao Wu, Yuchen Wang, Rui Qi, Dheeraj Bhavanasi, Zhixiang Zuo, Cedric Dos Santos, Shuliang Chen, Yu Chen, Hong Zheng, Hong Wang, Alexander Perl, Deyin Guo, Jian Huang

Cancer Res. Author manuscript; available in PMC 2018 Aug 15.

Published in final edited form as: Cancer Res. 2017 Aug 15; 77(16): 4402–4413. Published online 2017 Jun 16. doi: 10.1158/0008-5472.CAN-16-1627

PMCID:: PMC5559306

Abstract Article PDF–885K

Select item 53240647.

Whole-Genome Sequencing of a Family with Hereditary Pulmonary Alveolar Proteinosis Identifies a Rare Structural Variant Involving CSF2RA/CRLF2/IL3RA Gene Disruption

Chih-Yung Chiu, Shih-Chi Su, Wen-Lang Fan, Shen-Hao Lai, Ming-Han Tsai, Shih-Hsiang Chen, Kin-Sun Wong, Wen-Hung Chung

Sci Rep. 2017; 7: 43469. Published online 2017 Feb 24. doi: 10.1038/srep43469

PMCID:: PMC5324064

Abstract Article PDF–1.0M

Select item 42665888.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 42542589.

Characterization of CSF2RA mutation related juvenile pulmonary alveolar proteinosis

Jenna Hildebrandt, Ebru Yalcin, Hans-Georg Bresser, Guzin Cinel, Monika Gappa, Alireza Haghighi, Nural Kiper, Soheila Khalilzadeh, Karl Reiter, John Sayer, Nicolaus Schwerk, Anke Sibbersen, Sabine Van Daele, Georg Nübling, Peter Lohse, Matthias Griese

Orphanet J Rare Dis. 2014; 9: 171. Published online 2014 Nov 26. doi: 10.1186/s13023-014-0171-z

PMCID:: PMC4254258

Abstract Article PDF–778K

Select item 374693210.

Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein

Tory P. Johnson, Karan Patel, Kory R. Johnson, Dragan Maric, Peter A. Calabresi, Rodrigo Hasbun, Avindra Nath

Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33): 13588–13593. Published online 2013 Jul 29. doi: 10.1073/pnas.1308673110

PMCID:: PMC3746932

Abstract Article PDF–1002K

Select item 347831211.

Identification of a novel function of the clathrin-coated structure at the plasma membrane in facilitating GM-CSF receptor-mediated activation of JAK2

Ping-Hung Chen, Fan-Ching Chien, Sue-Ping Lee, Woan-Eng Chan, I-Hsuan Lin, Chun-Shan Liu, Fang-Jen Lee, Jiann-Shiun Lai, Peilin Chen, Hsin-Fang Yang-Yen, Jeffrey Jong-Young Yen

Cell Cycle. 2012 Oct 1; 11(19): 3611–3626. doi: 10.4161/cc.21920

PMCID:: PMC3478312

Abstract Article PDF–6.8M

Select item 336220712.

Defective Leukocyte GM-CSF Receptor (CD116) Expression and Function in Inflammatory Bowel Disease

Jonathan I. Goldstein, Douglas J. Kominsky, Nicole Jacobson, Brittelle Bowers, Kirsten Regalia, Gregory L. Austin, Melinda Yousefi, Michael T. Falta, Andrew P. Fontenot, Mark E. Gerich, Lucy Golden-Mason, Sean P. Colgan

Gastroenterology. Author manuscript; available in PMC 2012 Jul 1.

Published in final edited form as: Gastroenterology. 2011 Jul; 141(1): 208–216. Published online 2011 Apr 7. doi: 10.1053/j.gastro.2011.03.060

PMCID:: PMC3362207

Abstract Article PDF–2.0M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 258585114.

Pulmonary alveolar proteinosis caused by deletion of the GM-CSFRα gene in the X chromosome pseudoautosomal region 1

Margarita Martinez-Moczygemba, Minh L. Doan, Okan Elidemir, Leland L. Fan, Sau Wai Cheung, Jonathan T. Lei, James P. Moore, Ghamartaj Tavana, Lora R. Lewis, Yiming Zhu, Donna M. Muzny, Richard A. Gibbs, David P. Huston

J Exp Med. 2008 Nov 24; 205(12): 2711–2716. doi: 10.1084/jem.20080759

PMCID:: PMC2585851

Abstract Article PDF–1.7M

Select item 258584515.

Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA

Takuji Suzuki, Takuro Sakagami, Bruce K. Rubin, Lawrence M. Nogee, Robert E. Wood, Sarah L. Zimmerman, Teresa Smolarek, Megan K. Dishop, Susan E. Wert, Jeffrey A. Whitsett, Gregory Grabowski, Brenna C. Carey, Carrie Stevens, Johannes C.M. van der Loo, Bruce C. Trapnell

J Exp Med. 2008 Nov 24; 205(12): 2703–2710. doi: 10.1084/jem.20080990