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Select item 111301441.

FNDC5 prevents oxidative stress and neuronal apoptosis after traumatic brain injury through SIRT3-dependent regulation of mitochondrial quality control

Yufeng Ge, Xun Wu, Yaning Cai, Qing Hu, Jin Wang, Shenghao Zhang, Baocheng Zhao, Wenxing Cui, Yang Wu, Qiang Wang, Tian Feng, Haixiao Liu, Yan Qu, Shunnan Ge

Cell Death Dis. 2024 May; 15(5): 364. Published online 2024 May 27. doi: 10.1038/s41419-024-06748-w

Correction in:: Cell Death Dis. 2024 Jul; 15(7): 527.

PMCID:: PMC11130144

Abstract Article PDF–7.2M

Select item 111137152.

A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels

Alessia Peserico, Fulvio Chiacchiera, Valentina Grossi, Antonio Matrone, Dominga Latorre, Marta Simonatto, Aurora Fusella, James G. Ryall, Lydia W. S. Finley, Marcia C. Haigis, Gaetano Villani, Pier Lorenzo Puri, Vittorio Sartorelli, Cristiano Simone

Cell Mol Life Sci. 2013 Jun; 70(11): 2015–2029. Published online 2013 Jan 3. doi: 10.1007/s00018-012-1244-6

PMCID:: PMC11113715

Abstract Article PDF–1.3M

Select item 110206833.

SIRT3 regulates cardiolipin biosynthesis in pressure overload-induced cardiac remodeling by PPARγ-mediated mechanism

Ling-Xin Liu, Xue-Hui Zheng, Jing-Han Hai, Chun-Mei Zhang, Yun Ti, Tong-Shuai Chen, Pei-Li Bu

PLoS One. 2024; 19(4): e0301990. Published online 2024 Apr 16. doi: 10.1371/journal.pone.0301990

PMCID:: PMC11020683

Abstract Article PDF–3.7M

Select item 110121194.

Gene Expression Profiling Reveals Fundamental Sex-Specific Differences in SIRT3-Mediated Redox and Metabolic Signaling in Mouse Embryonic Fibroblasts

Robert Belužić, Ena Šimunić, Iva I. Podgorski, Marija Pinterić, Marijana Popović Hadžija, Tihomir Balog, Sandra Sobočanec

Int J Mol Sci. 2024 Apr; 25(7): 3868. Published online 2024 Mar 30. doi: 10.3390/ijms25073868

PMCID:: PMC11012119

Abstract Article PDF–3.4M

Select item 109665445.

Role of Argininosuccinate Synthase 1 ‐Dependent L‐Arginine Biosynthesis in the Protective Effect of Endothelial Sirtuin 3 Against Atherosclerosis

Xiaoyun Cao, Vivian Wei Yan Wu, Yumeng Han, Huiling Hong, Yalan Wu, Alice Pik Shan Kong, Kathy O Lui, Xiao Yu Tian

Adv Sci (Weinh) 2024 Mar; 11(12): 2307256. Published online 2024 Jan 17. doi: 10.1002/advs.202307256

PMCID:: PMC10966544

Abstract Article PDF–8.6M

Select item 109176606.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108300867.

Sirtuin3 promotes the degradation of hepatic Z alpha-1 antitrypsin through lipophagy

Brittney Poole, Regina Oshins, Zhiguang Huo, Alek Aranyos, Jesse West, Sergio Duarte, Virginia C. Clark, Thiago Beduschi, Ali Zarrinpar, Mark Brantly, Nazli Khodayari

Hepatol Commun. 2024 Feb; 8(2): e0370. Published online 2024 Jan 29. doi: 10.1097/HC9.0000000000000370

Correction in:: Hepatol Commun. 2024 Jun; 8(6): e0439.

PMCID:: PMC10830086

Abstract Article PDF–1.4M

Select item 108230658.

Sirt6 regulates the proliferation of neural precursor cells and cortical neurogenesis in mice

Yufei Wei, Xinhuan Wang, Zhihua Ma, Pan Xiang, Gaoao Liu, Bin Yin, Lin Hou, Pengcheng Shu, Wei Liu, Xiaozhong Peng

iScience. 2024 Feb 16; 27(2): 108706. Published online 2023 Dec 9. doi: 10.1016/j.isci.2023.108706

PMCID:: PMC10823065

Abstract Article PDF–8.1M

Select item 107976909.

The SIRT3-ATAD3A axis regulates MAM dynamics and mitochondrial calcium homeostasis in cardiac hypertrophy

Zeyu Li, Ou Hu, Suowen Xu, Chenjia Lin, Wenjing Yu, Dinghu Ma, Jing Lu, Peiqing Liu

Int J Biol Sci. 2024; 20(3): 831–847. Published online 2024 Jan 1. doi: 10.7150/ijbs.89253

PMCID:: PMC10797690

Abstract Article PDF–8.8M

Select item 1077788410.

Sirtuin 3 is required for the dexmedetomidine‐mediated alleviation of inflammation and oxidative stress in nephritis

Kai Lu, Xinlong Li, Jie Wu

Immun Inflamm Dis. 2024 Jan; 12(1): e1135. Published online 2024 Jan 10. doi: 10.1002/iid3.1135

PMCID:: PMC10777884

Abstract Article PDF–3.0M

Select item 1066369111.

Exogenous NADPH exerts a positive inotropic effect and enhances energy metabolism via SIRT3 in pathological cardiac hypertrophy and heart failure

Ke Qian, Jie Tang, Yue-Juan Ling, Ming Zhou, Xin-Xin Yan, Yu Xie, Lu-Jia Zhu, Koju Nirmala, Kang-Yun Sun, Zheng-Hong Qin, Rui Sheng

eBioMedicine. 2023 Dec; 98: 104863. Published online 2023 Nov 9. doi: 10.1016/j.ebiom.2023.104863

PMCID:: PMC10663691

Abstract Article PDF–4.9M

Select item 1056416312.

Sirt3 deficiency promotes endothelial dysfunction and aggravates renal injury

Anna Pezzotta, Luca Perico, Daniela Corna, Marina Morigi, Giuseppe Remuzzi, Ariela Benigni, Barbara Imberti

PLoS One. 2023; 18(10): e0291909. Published online 2023 Oct 10. doi: 10.1371/journal.pone.0291909

PMCID:: PMC10564163

Abstract Article PDF–3.1M

Select item 1049887213.

SIRT3 Regulates Clearance of Apoptotic Cardiomyocytes by Deacetylating Frataxin

Jing Gao, Chenglin Huang, Linghui Kong, Wugang Zhou, Mengwei Sun, Tong Wei, Weili Shen

Circ Res. 2023 Sep 15; 133(7): 631–647. Published online 2023 Aug 30. doi: 10.1161/CIRCRESAHA.123.323160

PMCID:: PMC10498872

Abstract Article PDF–14M

Select item 1049650514.

Sirtuin-3 activates the mitochondrial unfolded protein response and reduces cerebral ischemia/reperfusion injury

Xie Xiaowei, Xu Qian, Zhou Dingzhou

Int J Biol Sci. 2023; 19(13): 4327–4339. Published online 2023 Aug 21. doi: 10.7150/ijbs.86614

PMCID:: PMC10496505

Abstract Article PDF–12M

Select item 1043301315.

Increased SIRT3 combined with PARP inhibition rescues motor function of SBMA mice

David R. Garcia Castro, Joseph R. Mazuk, Erin M. Heine, Daniel Simpson, R. Seth Pinches, Caroline Lozzi, Kathryn Hoffman, Phillip Morrin, Dylan Mathis, Maria V. Lebedev, Elyse Nissley, Kang Hoo Han, Tyler Farmer, Diane E. Merry, Qiang Tong, Maria Pennuto, Heather L. Montie

iScience. 2023 Aug 18; 26(8): 107375. Published online 2023 Jul 22. doi: 10.1016/j.isci.2023.107375