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Select item 98679821.

Hematopoietic cytoplasmic adaptor protein Hem1 promotes osteoclast fusion and bone resorption in mice

Xiaoyan Wang, Lijian Shao, Kimberly K. Richardson, Wen Ling, Aaron Warren, Kimberly Krager, Nukhet Aykin-Burns, Robert Hromas, Daohong Zhou, Maria Almeida, Ha-Neui Kim

J Biol Chem. 2023 Feb; 299(2): 102841. Published online 2022 Dec 24. doi: 10.1016/j.jbc.2022.102841

PMCID:: PMC9867982

Abstract Article PDF–2.3M

Select item 90902612.

Hem-1 regulates protective humoral immunity and limits autoantibody production in a B cell–specific manner

Alan Avalos, Jacob T. Tietsort, Nutthakarn Suwankitwat, Jonathan D. Woods, Shaun W. Jackson, Alexandra Christodoulou, Christopher Morrill, H. Denny Liggitt, Chengsong Zhu, Quan-Zhen Li, Kevin K. Bui, Heon Park, Brian M. Iritani

JCI Insight. 2022 May 9; 7(9): e153597. Published online 2022 May 9. doi: 10.1172/jci.insight.153597

PMCID:: PMC9090261

Abstract Article PDF–2.1M

Select item 78940473.

The actin-regulatory protein Hem-1 is essential for alveolar macrophage development

Nutthakarn Suwankitwat, Stephen Libby, H. Denny Liggitt, Alan Avalos, Alanna Ruddell, Jason W. Rosch, Heon Park, Brian M. Iritani

J Exp Med. 2021 Apr 5; 218(4): e20200472. Published online 2021 Feb 17. doi: 10.1084/jem.20200472

PMCID:: PMC7894047

Abstract Article PDF–5.4M

Select item 71167564.

The cytoskeletal regulator HEM1 governs B-cell development and prevents autoimmunity

Elisabeth Salzer, Samaneh Zoghi, Máté G. Kiss, Frieda Kage, Christina Rashkova, Stephanie Stahnke, Matthias Haimel, René Platzer, Michael Caldera, Rico Chandra Ardy, Birgit Hoeger, Jana Block, David Medgyesi, Celine Sin, Sepideh Shahkarami, Renate Kain, Vahid Ziaee, Peter Hammerl, Christoph Bock, Jörg Menche, Loïc Dupré, Johannes B. Huppa, Michael Sixt, Alexis Lomakin, Klemens Rottner, Christoph J. Binder, Theresia E.B. Stradal, Nima Rezaei, Kaan Boztug

Sci Immunol. Author manuscript; available in PMC 2021 Feb 15.

Published in final edited form as: Sci Immunol. 2020 Jul 10; 5(49): eabc3979. Published online 2020 Jul 10. doi: 10.1126/sciimmunol.abc3979

PMCID:: PMC7116756

Abstract Article PDF–2.7M

Select item 62627775.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow

Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher

J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214

PMCID:: PMC6262777

Abstract Article

Select item 60061466.

The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow

Lijian Shao, Jianhui Chang, Wei Feng, Xiaoyan Wang, Elizabeth A. Williamson, Ying Li, Amir Schajnovitz, David Scadden, Luke J. Mortensen, Charles P. Lin, Linheng Li, Ariel Paulson, James Downing, Daohong Zhou, Robert A. Hromas

Nat Commun. 2018; 9: 2377. Published online 2018 Jun 18. doi: 10.1038/s41467-018-04716-5

PMCID:: PMC6006146

Abstract Article PDF–1.1M

Select item 56606077.

A functional genomics predictive network model identifies regulators of inflammatory bowel disease

Lauren A Peters, Jacqueline Perrigoue, Arthur Mortha, Alina Iuga, Won-min Song, Eric M Neiman, Sean R Llewellyn, Antonio Di Narzo, Brian A Kidd, Shannon E Telesco, Yongzhong Zhao, Aleksandar Stojmirovic, Jocelyn Sendecki, Khader Shameer, Riccardo Miotto, Bojan Losic, Hardik Shah, Eunjee Lee, Minghui Wang, Jeremiah J Faith, Andrew Kasarskis, Carrie Brodmerkel, Mark Curran, Anuk Das, Joshua R Friedman, Yoshinori Fukui, Mary Beth Humphrey, Brian M Iritani, Nicholas Sibinga, Teresa K Tarrant, Carmen Argmann, Ke Hao, Panos Roussos, Jun Zhu, Bin Zhang, Radu Dobrin, Lloyd F Mayer, Eric E Schadt

Nat Genet. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Nat Genet. 2017 Oct; 49(10): 1437–1449. Published online 2017 Sep 11. doi: 10.1038/ng.3947

PMCID:: PMC5660607

Abstract Article PDF–1.6M

Select item 53812268.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 53082189.

The Proximal Signaling Network of the BCR-ABL1 Oncogene Shows a Modular Organization

Björn Titz, Tracey Low, Evangelia Komisopoulou, Sharon S Chen, Liudmilla Rubbi, Thomas G Graeber

Oncogene. Author manuscript; available in PMC 2017 Feb 14.

Published in final edited form as: Oncogene. 2010 Nov 4; 29(44): 5895–5910. Published online 2010 Aug 9. doi: 10.1038/onc.2010.331

PMCID:: PMC5308218

Abstract Article PDF–3.8M

Select item 479636510.

Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments

Hawa-Racine Thiam, Pablo Vargas, Nicolas Carpi, Carolina Lage Crespo, Matthew Raab, Emmanuel Terriac, Megan C. King, Jordan Jacobelli, Arthur S. Alberts, Theresia Stradal, Ana-Maria Lennon-Dumenil, Matthieu Piel

Nat Commun. 2016; 7: 10997. Published online 2016 Mar 15. doi: 10.1038/ncomms10997

PMCID:: PMC4796365

Abstract Article PDF–2.5M

Select item 357241011.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 357053112.

Hematopoietic Protein-1 Regulates the Actin Membrane Skeleton and Membrane Stability in Murine Erythrocytes

Maia M. Chan, Jason M. Wooden, Mark Tsang, Diana M. Gilligan, Dinesh K. Hirenallur-S, Greg L. Finney, Eric Rynes, Michael MacCoss, Julita A. Ramirez, Heon Park, Brian M. Iritani

PLoS One. 2013; 8(2): e54902. Published online 2013 Feb 12. doi: 10.1371/journal.pone.0054902

PMCID:: PMC3570531

Abstract Article PDF–1.3M

Select item 344801213.

Transcription factor Foxp3 and its protein partners form a complex regulatory network

Dipayan Rudra, Paul deRoos, Ashutosh Chaudhry, Rachel Niec, Aaron Arvey, Robert M. Samstein, Christina Leslie, Scott A. Shaffer, David R. Goodlett, Alexander Y. Rudensky

Nat Immunol. Author manuscript; available in PMC 2013 Apr 1.

Published in final edited form as: Nat Immunol. 2012 Oct; 13(10): 1010–1019. Published online 2012 Aug 26. doi: 10.1038/ni.2402

PMCID:: PMC3448012

Abstract Article PDF–2.6M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253415.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 258584016.

A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic Protein 1 in lymphopoiesis and innate immunity

Heon Park, Karen Staehling-Hampton, Mark W. Appleby, Mary E. Brunkow, Tania Habib, Yi Zhang, Fred Ramsdell, H. Denny Liggitt, Brian Freie, Mark Tsang, George Carlson, Sherree Friend, Charles Frevert, Brian M. Iritani

J Exp Med. 2008 Nov 24; 205(12): 2899–2913. doi: 10.1084/jem.20080340

PMCID:: PMC2585840

Abstract Article PDF–9.2M

Select item 31111917.

Construction of Long-Transcript Enriched cDNA Libraries from Submicrogram Amounts of Total RNAs by a Universal PCR Amplification Method

Yulan Piao, Naomi T. Ko, Meng K. Lim, Minoru S.H. Ko

Genome Res. 2001 Sep; 11(9): 1553–1558. doi: 10.1101/gr.185501

PMCID:: PMC311119

Abstract Article PDF–743K

Select item 31099218.

RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki

Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600

PMCID:: PMC310992

Abstract Article PDF–3.4M

Select item 31098019.

Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes

Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki

Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100

PMCID:: PMC310980

Abstract Article PDF–1.4M

Select item 13924120.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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