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Items: 1 to 20 of 357

1.
New mechanistic understanding of osteoclast differentiation and bone resorption mediated by P2X7 receptors and PI3K-Akt-GSK3β signaling
Jiajia Lu, Xiaojian Shi, Qiang Fu, Yaguang Han, Lei Zhu, Zhibin Zhou, Yongchuan Li, Nan Lu
Cell Mol Biol Lett. 2024; 29: 100. Published online 2024 Jul 8. doi: 10.1186/s11658-024-00614-5
PMCID:
PMC11232284
AbstractArticlePDF–2.7M
2.
Different localization of P2X4 and P2X7 receptors in native mouse lung - lack of evidence for a direct P2X4-P2X7 receptor interaction
Juan Sierra-Marquez, Lena Schaller, Lukas Sassenbach, Antonio Ramírez-Fernández, Philipp Alt, Björn Rissiek, Béla Zimmer, Johann Schredelseker, Julia Hector, Tobias Stähler, Friedrich Koch-Nolte, Claudia A. Staab-Weijnitz, Alexander Dietrich, Robin Kopp, Annette Nicke
Front Immunol. 2024; 15: 1425938. Published online 2024 Jun 17. doi: 10.3389/fimmu.2024.1425938
PMCID:
PMC11215518
AbstractArticlePDF–3.8M
3.
Behavioral and cortical arousal from sleep, muscimol-induced coma, and anesthesia by direct optogenetic stimulation of cortical neurons
Rong Mao, Matias Lorenzo Cavelli, Graham Findlay, Kort Driessen, Michael J. Peterson, William Marshall, Giulio Tononi, Chiara Cirelli
iScience. 2024 Jun 21; 27(6): 109919. Published online 2024 May 7. doi: 10.1016/j.isci.2024.109919
PMCID:
PMC11134913
AbstractArticlePDF–9.5M
4.
P2X7R and P2X4R expression of mice submandibular gland in high-fat diet/streptozotocin-induced type 2 diabetes
Jiratchaya Srisutha, Ippei Watari, Masato Akakura, Minami Watanabe, Chidsanu Changsiripun, Takashi Ono
Sci Rep. 2024; 14: 10855. Published online 2024 May 13. doi: 10.1038/s41598-024-60519-3
PMCID:
PMC11091137
AbstractArticlePDF–17M
5.
The purinergic receptor P2X7 as a modulator of viral vector-mediated antigen cross-presentation
Ylenia Longo, Sara Moreno Mascaraque, Giuseppe Andreacchio, Julia Werner, Ichiro Katahira, Elena De Marchi, Anna Pegoraro, Robert Jan Lebbink, Karl Köhrer, Patrick Petzsch, Ronny Tao, Francesco Di Virgilio, Elena Adinolfi, Ingo Drexler
Front Immunol. 2024; 15: 1360140. Published online 2024 Apr 22. doi: 10.3389/fimmu.2024.1360140
PMCID:
PMC11070468
AbstractArticlePDF–3.0M
6.
Angiotension II directly bind P2X7 receptor to induce myocardial ferroptosis and remodeling by activating human antigen R
Xin Zhong, Kangwei Wang, Yonghua Wang, Luya Wang, Sudan Wang, Weijian Huang, Zhuyin Jia, Shan-Shan Dai, Zhouqing Huang
Redox Biol. 2024 Jun; 72: 103154. Published online 2024 Apr 9. doi: 10.1016/j.redox.2024.103154
PMCID:
PMC11035111
AbstractArticlePDF–19M
7.
Adaptation of sequential action benefits from timing variability related to lateral basal ganglia circuitry
Lachlan A. Ferguson, Miriam Matamales, Christopher Nolan, Bernard W. Balleine, Jesus Bertran-Gonzalez
iScience. 2024 Mar 15; 27(3): 109274. Published online 2024 Feb 20. doi: 10.1016/j.isci.2024.109274
PMCID:
PMC10943431
AbstractArticlePDF–28M
8.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
9.
Time-resolved role of P2X4 and P2X7 during CD8+ T cell activation
Valerie J. Brock, Niels Christian Lory, Franziska Möckl, Melina Birus, Tobias Stähler, Lena-Marie Woelk, Michelle Jaeckstein, Joerg Heeren, Friedrich Koch-Nolte, Björn Rissiek, Hans-Willi Mittrücker, Andreas H. Guse, René Werner, Björn-Philipp Diercks
Front Immunol. 2024; 15: 1258119. Published online 2024 Feb 15. doi: 10.3389/fimmu.2024.1258119
PMCID:
PMC10902106
AbstractArticlePDF–3.8M
10.
T cell-specific P2RX7 favors lung parenchymal CD4+ T cell accumulation in response to severe lung infections
Igor Santiago-Carvalho, Gislane Almeida-Santos, Bruna Gois Macedo, Caio Cesar Barbosa-Bomfim, Fabricio Moreira Almeida, Marcos Vinícios Pinheiro Cione, Trupti Vardam-Kaur, Mia Masuda, Sarah Van Dijk, Bruno Marcel Melo, Rogério Silva do Nascimento, Rebeka da Conceição Souza, Alba Lucínia Peixoto-Rangel, Robson Coutinho-Silva, Mario Hiroyuki Hirata, José Carlos Alves-Filho, José Maria Álvarez, Elena Lassounskaia, Henrique Borges da Silva, Maria Regina D’Império-Lima
Cell Rep. Author manuscript; available in PMC 2024 Feb 5.
Published in final edited form as: Cell Rep. 2023 Nov 28; 42(11): 113448. Published online 2023 Nov 15. doi: 10.1016/j.celrep.2023.113448
PMCID:
PMC10841667
AbstractArticlePDF–3.2M
11.
Intestinal transit-amplifying cells require METTL3 for growth factor signaling and cell survival
Charles H. Danan, Kaitlyn E. Naughton, Katharina E. Hayer, Sangeevan Vellappan, Emily A. McMillan, Yusen Zhou, Rina Matsuda, Shaneice K. Nettleford, Kay Katada, Louis R. Parham, Xianghui Ma, Afrah Chowdhury, Benjamin J. Wilkins, Premal Shah, Matthew D. Weitzman, Kathryn E. Hamilton
JCI Insight. 2023 Dec 8; 8(23): e171657. Published online 2023 Dec 8. doi: 10.1172/jci.insight.171657
PMCID:
PMC10795831
AbstractArticlePDF–5.8M
12.
P2Y2-P2X7 receptors cross-talk in primed mesenteric endothelial cells upregulates NF-κB signaling favoring mononuclear cell adhesion in schistosomiasis
Nathália Ferreira Oliveira, Matheus Macedo L. V. Monteiro, Nathália Santos Mainieri, Augusto Shuiti Tamura, Letícia Massimo Pereira, Leticia Diniz Crepaldi, Robson Coutinho-Silva, Luiz Eduardo Baggio Savio, Claudia Lucia Martins Silva
Front Immunol. 2023; 14: 1328897. Published online 2024 Jan 4. doi: 10.3389/fimmu.2023.1328897
PMCID:
PMC10794548
AbstractArticlePDF–6.1M
13.
P2X7 receptor activation awakes a dormant stem cell niche in the adult spinal cord
María Victoria Falco, Gabriela Fabbiani, Cecilia Maciel, Spring Valdivia, Nathalia Vitureira, Raúl E. Russo
Front Cell Neurosci. 2023; 17: 1288676. Published online 2023 Dec 18. doi: 10.3389/fncel.2023.1288676
PMCID:
PMC10757934
AbstractArticlePDF–2.6M
14.
δ-Catenin controls astrocyte morphogenesis via layer-specific astrocyte–neuron cadherin interactions
Christabel Xin Tan, Dhanesh Sivadasan Bindu, Evelyn J. Hardin, Kristina Sakers, Ryan Baumert, Juan J. Ramirez, Justin T. Savage, Cagla Eroglu
J Cell Biol. 2023 Nov 6; 222(11): e202303138. Published online 2023 Sep 14. doi: 10.1083/jcb.202303138
PMCID:
PMC10501387
AbstractArticlePDF–8.5M
15.
P2X7 purinergic receptor modulates dentate gyrus excitatory neurotransmission and alleviates schizophrenia-like symptoms in mouse
Lumei Huang, Paula Mut-Arbona, Bernadett Varga, Bibiana Török, János Brunner, Antonia Arszovszki, András Iring, Máté Kisfali, E. Sylvester Vizi, Beáta Sperlágh
iScience. 2023 Sep 15; 26(9): 107560. Published online 2023 Aug 7. doi: 10.1016/j.isci.2023.107560
PMCID:
PMC10462828
AbstractArticlePDF–7.4M
16.
P2X7 Receptor Regulates Collagen Expression in Human Intestinal Fibroblasts: Relevance in Intestinal Fibrosis
Lluis Lis-López, Cristina Bauset, Marta Seco-Cervera, Dulce Macias-Ceja, Francisco Navarro, Ángeles Álvarez, Juan Vicente Esplugues, Sara Calatayud, Maria Dolores Barrachina, Dolores Ortiz-Masià, Jesús Cosín-Roger
Int J Mol Sci. 2023 Aug; 24(16): 12936. Published online 2023 Aug 18. doi: 10.3390/ijms241612936
PMCID:
PMC10454509
AbstractArticlePDF–3.6M
17.
Study of the roles of caspase-3 and nuclear factor kappa B in myenteric neurons in a P2X7 receptor knockout mouse model of ulcerative colitis
Henrique Inhauser Riceti Magalhães, Felipe Alexandre Machado, Roberta Figueiroa Souza, Marcos Antônio Ferreira Caetano, Vanessa Ribeiro Figliuolo, Robson Coutinho-Silva, Patricia Castelucci
World J Gastroenterol. 2023 Jun 14; 29(22): 3440–3468. Published online 2023 Jun 14. doi: 10.3748/wjg.v29.i22.3440
PMCID:
PMC10303518
AbstractArticlePDF–57M
18.
The Pannexin 1 Channel and the P2X7 Receptor Are in Complex Interplay to Regulate the Release of Soluble Ectonucleotidases in the Murine Bladder Lamina Propria
Mafalda S. L. Aresta Branco, Alejandro Gutierrez Cruz, Lauren E. Peri, Violeta N. Mutafova-Yambolieva
Int J Mol Sci. 2023 Jun; 24(12): 9964. Published online 2023 Jun 9. doi: 10.3390/ijms24129964
PMCID:
PMC10298213
AbstractArticlePDF–4.7M
19.
P2X7 receptor inhibition ameliorates ubiquitin–proteasome system dysfunction associated with Alzheimer’s disease
Carolina Bianchi, Beatriz Alvarez-Castelao, Álvaro Sebastián-Serrano, Caterina Di Lauro, Lucia Soria-Tobar, Annette Nicke, Tobias Engel, Miguel Díaz-Hernández
Alzheimers Res Ther. 2023; 15: 105. Published online 2023 Jun 7. doi: 10.1186/s13195-023-01258-x
PMCID:
PMC10245610
AbstractArticlePDF–10M
20.
Upregulation of P2X7 Exacerbates Myocardial Ischemia–Reperfusion Injury through Enhancing Inflammation and Apoptosis in Diabetic Mice
Fancan Wu, Hong Wei, Yingxin Hu, Jiahong Gao, Shiyuan Xu
J Immunol. 2023 Jun 15; 210(12): 1962–1973. Published online 2023 May 5. doi: 10.4049/jimmunol.2200838
PMCID:
PMC10235857
AbstractArticlePDF–4.7M

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