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Select item 105455941.

Intracellular FGF1 protects cells from apoptosis through direct interaction with p53

Agata Lampart, Daniel Krowarsch, Martyna Biadun, Vigdis Sorensen, Jakub Szymczyk, Katarzyna Sluzalska, Antoni Wiedlocha, Jacek Otlewski, Malgorzata Zakrzewska

Cell Mol Life Sci. 2023 Oct; 80(10): 311. Published online 2023 Oct 2. doi: 10.1007/s00018-023-04964-9

PMCID:: PMC10545594

Abstract Article PDF–4.5M

Select item 88339432.

Nuclear Localization Sequence of FGF1 Is Not Required for Its Intracellular Anti-Apoptotic Activity in Differentiated Cells

Agata Lampart, Katarzyna Dominika Sluzalska, Aleksandra Czyrek, Aleksandra Szerszen, Jacek Otlewski, Antoni Wiedlocha, Malgorzata Zakrzewska

Cells. 2022 Feb; 11(3): 522. Published online 2022 Feb 2. doi: 10.3390/cells11030522

PMCID:: PMC8833943

Abstract Article PDF–2.2M

Select item 83919773.

Functional Roles of FGF Signaling in Early Development of Vertebrate Embryos

Vijay Kumar, Ravi Shankar Goutam, Soochul Park, Unjoo Lee, Jaebong Kim

Cells. 2021 Aug; 10(8): 2148. Published online 2021 Aug 20. doi: 10.3390/cells10082148

PMCID:: PMC8391977

Abstract Article PDF–1.4M

Select item 83291564.

Characterization of the structural forces governing the reversibility of the thermal unfolding of the human acidic fibroblast growth factor

Shilpi Agrawal, Vivek Govind Kumar, Ravi Kumar Gundampati, Mahmoud Moradi, Thallapuranam Krishnaswamy Suresh Kumar

Sci Rep. 2021; 11: 15579. Published online 2021 Aug 2. doi: 10.1038/s41598-021-95050-2

PMCID:: PMC8329156

Abstract Article PDF–1.4M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79033516.

Stress-induced NEDDylation promotes cytosolic protein aggregation through HDAC6 in a p62-dependent manner

Soyeon Kim, Mira Kwon, Yiseul Hwang, Junghyun Yoon, Sangwook Park, Ho Chul Kang

iScience. 2021 Mar 19; 24(3): 102146. Published online 2021 Feb 6. doi: 10.1016/j.isci.2021.102146

PMCID:: PMC7903351

Abstract Article PDF–49M

Select item 74840587.

Lineage‐specific differentiation of osteogenic progenitors from pluripotent stem cells reveals the FGF1‐RUNX2 association in neural crest‐derived osteoprogenitors

Fahad Kidwai, Byron W. H. Mui, Deepika Arora, Kulsum Iqbal, Madison Hockaday, Luis Fernandez de Castro Diaz, Natasha Cherman, Daniel Martin, Vamsee D. Myneni, Moaz Ahmad, Katarzyna Futrega, Sania Ali, Randall K. Merling, Dan S. Kaufman, Janice Lee, Pamela G. Robey

Stem Cells. 2020 Sep; 38(9): 1107–1123. Published online 2020 Jun 9. doi: 10.1002/stem.3206

PMCID:: PMC7484058

Abstract Article PDF–14M

Select item 74681618.

FGF/FGFR signaling in health and disease

Yangli Xie, Nan Su, Jing Yang, Qiaoyan Tan, Shuo Huang, Min Jin, Zhenhong Ni, Bin Zhang, Dali Zhang, Fengtao Luo, Hangang Chen, Xianding Sun, Jian Q. Feng, Huabing Qi, Lin Chen

Signal Transduct Target Ther. 2020; 5: 181. Published online 2020 Sep 2. doi: 10.1038/s41392-020-00222-7

PMCID:: PMC7468161

Abstract Article PDF–3.4M

Select item 73981679.

Acidic fibroblast growth factor underlies microenvironmental regulation of MYC in pancreatic cancer

Sohinee Bhattacharyya, Chet Oon, Aayush Kothari, Wesley Horton, Jason Link, Rosalie C. Sears, Mara H. Sherman

J Exp Med. 2020 Aug 3; 217(8): e20191805. Published online 2020 May 20. doi: 10.1084/jem.20191805

PMCID:: PMC7398167

Abstract Article PDF–5.6M

Select item 717143210.

Fibroblast Growth Factor (FGF) Signaling Protects Against Acute Pancreatitis-Induced Damage by Modulating Inflammatory Responses

Hai-Jian Tu, Cheng-Fei Zhao, Zhi-wei Chen, Wei Lin, Yu-Cai Jiang

Med Sci Monit. 2020; 26: e920684-1–e920684-10. Prepublished online 2020 Feb 17. Published online 2020 Apr 13. doi: 10.12659/MSM.920684

PMCID:: PMC7171432

Abstract Article PDF–975K

Select item 716998311.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 689119312.

Adaptive Resistance to Dual BRAF/MEK Inhibition in BRAF-Driven Tumors Through Autocrine FGFR Pathway Activation

Victoria E. Wang, Jenny Y. Xue, Dennie T. Frederick, Yi Cao, Eva Lin, Catherine Wilson, Anatoly Urisman, David P. Carbone, Keith T. Flaherty, Rene Bernards, Piro Lito, Jeff Settleman, Frank McCormick

Clin Cancer Res. Author manuscript; available in PMC 2020 Jun 1.

Published in final edited form as: Clin Cancer Res. 2019 Dec 1; 25(23): 7202–7217. Published online 2019 Sep 12. doi: 10.1158/1078-0432.CCR-18-2779

PMCID:: PMC6891193

Abstract Article PDF–2.1M

Select item 672165713.

Low Stability of Integrin-Binding Deficient Mutant of FGF1 Restricts Its Biological Activity

Anna Szlachcic, Martyna Sochacka, Aleksandra Czyrek, Lukasz Opalinski, Daniel Krowarsch, Jacek Otlewski, Malgorzata Zakrzewska

Cells. 2019 Aug; 8(8): 899. Published online 2019 Aug 15. doi: 10.3390/cells8080899

PMCID:: PMC6721657

Abstract Article PDF–4.5M

Select item 667066414.

Synaptic Function for the Nogo-66 Receptor NgR1: Regulation of Dendritic Spine Morphology and Activity-Dependent Synaptic Strength

Hakjoo Lee, Stephen J. Raiker, Karthik Venkatesh, Rebecca Geary, Laurie A. Robak, Yu Zhang, Hermes H. Yeh, Peter Shrager, Roman J. Giger

J Neurosci. 2008 Mar 12; 28(11): 2753–2765. doi: 10.1523/JNEUROSCI.5586-07.2008

PMCID:: PMC6670664

Abstract Article PDF–802K

Select item 653347515.

miRNA‐210‐3p regulates trophoblast proliferation and invasiveness through fibroblast growth factor 1 in selective intrauterine growth restriction

Lin Li, Xuan Huang, Zhiming He, Yuanyan Xiong, Qun Fang

J Cell Mol Med. 2019 Jun; 23(6): 4422–4433. Published online 2019 Apr 16. doi: 10.1111/jcmm.14335

PMCID:: PMC6533475

Abstract Article PDF–1.9M

Select item 607772216.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 598012917.

Humanization of fibroblast growth factor 1 single‐chain antibody and validation for its antitumorigenic efficacy in breast cancer and glioma cells

Xiao‐Xiao He, Shuang Du, Shi‐Qian Gao, Jing‐Ying Chen, Ran‐Juan Cao, Zhen‐Kai Xing, Alia Rizvi Syeda Kazim, Hua‐Li Yu, Qing‐Chuan Zheng, Xiao‐Juan Zhu

J Cell Mol Med. 2018 Jun; 22(6): 3259–3263. Published online 2018 Mar 24. doi: 10.1111/jcmm.13547

PMCID:: PMC5980129

Abstract Article PDF–1.0M

Select item 585262718.

A novel fibroblast growth factor-1 ligand with reduced heparin binding protects the heart against ischemia-reperfusion injury in the presence of heparin co-administration

Chahua Huang, Yang Liu, Andrew Beenken, Lin Jiang, Xiang Gao, Zhifeng Huang, Anna Hsu, Garrett J. Gross, Yi-Gang Wang, Moosa Mohammadi, Jo El J. Schultz

Cardiovasc Res. 2017 Nov; 113(13): 1585–1602. Published online 2017 Sep 7. doi: 10.1093/cvr/cvx165

PMCID:: PMC5852627

Abstract Article PDF–1.8M

Select item 583009119.

Long non-coding RNA Gas5 regulates proliferation and apoptosis in HCS-2/8 cells and growth plate chondrocytes by controlling FGF1 expression via miR-21 regulation

Xiong Liu, Yuqi She, Hongrong Wu, Da Zhong, Jian Zhang

J Biomed Sci. 2018; 25: 18. Published online 2018 Feb 28. doi: 10.1186/s12929-018-0424-6

PMCID:: PMC5830091

Abstract Article PDF–2.8M

Select item 559658520.

FGF1 protects neuroblastoma SH-SY5Y cells from p53-dependent apoptosis through an intracrine pathway regulated by FGF1 phosphorylation

Caroline Pirou, Fatemeh Montazer-Torbati, Nadège Jah, Elisabeth Delmas, Christelle Lasbleiz, Bernard Mignotte, Flore Renaud

Cell Death Dis. 2017 Aug; 8(8): e3023. Published online 2017 Aug 31. doi: 10.1038/cddis.2017.404

PMCID:: PMC5596585

Abstract Article PDF–1.0M

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