PMC Links for GEO Profiles (Select 65092416) - PMC

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 82675664.

Human GPR17 missense variants identified in metabolic disease patients have distinct downstream signaling profiles

Jason M. Conley, Hongmao Sun, Kristin L. Ayers, Hu Zhu, Rong Chen, Min Shen, Matthew D. Hall, Hongxia Ren

J Biol Chem. 2021 Jul; 297(1): 100881. Published online 2021 Jun 16. doi: 10.1016/j.jbc.2021.100881

PMCID:: PMC8267566

Abstract Article PDF–3.7M

Select item 81977645.

G-protein-coupled receptor GPR17 inhibits glioma development by increasing polycomb repressive complex 1-mediated ROS production

Huiqing Liu, Rui Xing, Zhimin Ou, Junying Zhao, Guolin Hong, Tong-Jin Zhao, Ying Han, Ying Chen

Cell Death Dis. 2021 Jun; 12(6): 610. Published online 2021 Jun 12. doi: 10.1038/s41419-021-03897-0

PMCID:: PMC8197764

Abstract Article PDF–6.7M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81238497.

The Distribution of GPR17-Expressing Cells Correlates with White Matter Inflammation Status in Brain Tissues of Multiple Sclerosis Patients

Jacopo Angelini, Davide Marangon, Stefano Raffaele, Davide Lecca, Maria P. Abbracchio

Int J Mol Sci. 2021 May; 22(9): 4574. Published online 2021 Apr 27. doi: 10.3390/ijms22094574

PMCID:: PMC8123849

Abstract Article PDF–2.9M

Select item 80584328.

Microglial vesicles improve post-stroke recovery by preventing immune cell senescence and favoring oligodendrogenesis

Stefano Raffaele, Paolo Gelosa, Elisabetta Bonfanti, Marta Lombardi, Laura Castiglioni, Mauro Cimino, Luigi Sironi, Maria P. Abbracchio, Claudia Verderio, Marta Fumagalli

Mol Ther. 2021 Apr 7; 29(4): 1439–1458. Published online 2020 Dec 10. doi: 10.1016/j.ymthe.2020.12.009

PMCID:: PMC8058432

Abstract Article PDF–7.6M

Select item 53717309.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 433073710.

GPR17 gene disruption does not alter food intake or glucose homeostasis in mice

Jason Mastaitis, Soo Min, Ralf Elvert, Aimo Kannt, Yurong Xin, Francisca Ochoa, Nicholas W. Gale, David M. Valenzuela, Andrew J. Murphy, George D. Yancopoulos, Jesper Gromada

Proc Natl Acad Sci U S A. 2015 Feb 10; 112(6): 1845–1849. Published online 2015 Jan 26. doi: 10.1073/pnas.1424968112

PMCID:: PMC4330737

Abstract Article PDF–858K

Select item 411401811.

Decoding Signaling and Function of the Orphan G Protein–Coupled Receptor GPR17 with a Small-Molecule Agonist

Stephanie Hennen, Haibo Wang, Lucas Peters, Nicole Merten, Katharina Simon, Andreas Spinrath, Stefanie Blättermann, Rhalid Akkari, Ramona Schrage, Ralf Schröder, Daniel Schulz, Celine Vermeiren, Katrin Zimmermann, Stefan Kehraus, Christel Drewke, Alexander Pfeifer, Gabriele M. König, Klaus Mohr, Michel Gillard, Christa E. Müller, Q. Richard Lu, Jesus Gomeza, Evi Kostenis

Sci Signal. Author manuscript; available in PMC 2014 Jul 29.

Published in final edited form as: Sci Signal. 2013 Oct 22; 6(298): ra93. Published online 2013 Oct 22. doi: 10.1126/scisignal.2004350

PMCID:: PMC4114018

Abstract Article PDF–1.6M

Select item 378141512.

Is GPR17 a P2Y/Leukotriene Receptor? Examination of Uracil Nucleotides, Nucleotide Sugars, and Cysteinyl Leukotrienes as Agonists of GPR17

Ai-Dong Qi, T. Kendall Harden, Robert A. Nicholas

J Pharmacol Exp Ther. 2013 Oct; 347(1): 38–46. Published online 2013 Oct. doi: 10.1124/jpet.113.207647

PMCID:: PMC3781415

Abstract Article PDF–1.1M

Select item 375714913.

Changes of the GPR17 receptor, a new target for neurorepair, in neurons and glial cells in patients with traumatic brain injury

Heike Franke, Chiara Parravicini, Davide Lecca, Elisa R. Zanier, Claudia Heine, Kristina Bremicker, Marta Fumagalli, Patrizia Rosa, Luca Longhi, Nino Stocchetti, Maria-Grazia De Simoni, Marco Weber, Maria P. Abbracchio

Purinergic Signal. 2013 Sep; 9(3): 451–462. Published online 2013 Jun 26. doi: 10.1007/s11302-013-9366-3

PMCID:: PMC3757149

Abstract Article PDF–1.4M

Select item 357612814.

The Regulated Expression, Intracellular Trafficking, and Membrane Recycling of the P2Y-like Receptor GPR17 in Oli-neu Oligodendroglial Cells

Alessandra Fratangeli, Elena Parmigiani, Marta Fumagalli, Davide Lecca, Roberta Benfante, Maria Passafaro, Annalisa Buffo, Maria P. Abbracchio, Patrizia Rosa

J Biol Chem. 2013 Feb 15; 288(7): 5241–5256. Published online 2013 Jan 3. doi: 10.1074/jbc.M112.404996

PMCID:: PMC3576128

Abstract Article PDF–3.7M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 283926716.

Distinct expression and ligand-binding profiles of two constitutively active GPR17 splice variants

T Benned-Jensen, MM Rosenkilde

Br J Pharmacol. 2010 Mar; 159(5): 1092–1105. Published online 2010 Feb 8. doi: 10.1111/j.1476-5381.2009.00633.x

PMCID:: PMC2839267

Abstract Article PDF–854K

Select item 244381317.

GPR17: Molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors

Chiara Parravicini, Graziella Ranghino, Maria P Abbracchio, Piercarlo Fantucci

BMC Bioinformatics. 2008; 9: 263. Published online 2008 Jun 4. doi: 10.1186/1471-2105-9-263

PMCID:: PMC2443813

Abstract Article PDF–879K

Select item 158999118.

The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor

Paolo Ciana, Marta Fumagalli, Maria Letizia Trincavelli, Claudia Verderio, Patrizia Rosa, Davide Lecca, Silvia Ferrario, Chiara Parravicini, Valérie Capra, Paolo Gelosa, Uliano Guerrini, Silvia Belcredito, Mauro Cimino, Luigi Sironi, Elena Tremoli, G Enrico Rovati, Claudia Martini, Maria P Abbracchio

EMBO J. 2006 Oct 4; 25(19): 4615–4627. Published online 2006 Sep 21. doi: 10.1038/sj.emboj.7601341

PMCID:: PMC1589991

Abstract Article PDF–535K

Select item 135612919.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 52892820.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

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